Brain & spine最新文献

{"title":"Utility of ct hounsfield unit and mri vertebral bone quality score in assessing the risk of adjacent vertebral fracture following balloon kyphoplasty","authors":"H. Taniwaki , S. Takahashi , M. Hoshino , K. Tamai , H. Toyoda , A. Suzuki , M. Kato , H. Nakamura , H. Terai","doi":"10.1016/j.bas.2025.104891","DOIUrl":"10.1016/j.bas.2025.104891","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104891"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145324646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FREE-HAND INSERTION OF S2AI SCREW: WHAT CAN WE LEARN FROM O-ARM NAVIGATION?","authors":"F. CHANGSHENG , K. SUN , J. LI , L. ZHEN , Z. ZEZHANG , Q. YONG","doi":"10.1016/j.bas.2025.104797","DOIUrl":"10.1016/j.bas.2025.104797","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104797"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145324655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lumbar disc space height in relation to neural foraminal dimensions and patient characteristics: A morphometric analysis from L1-S1 using computed tomography","authors":"David Shin ,&nbsp;Ethan Vyhmeister ,&nbsp;Daniel Im ,&nbsp;Andrew Fay ,&nbsp;Owen Faehner ,&nbsp;Andrew Cabrera ,&nbsp;Alexander Bouterse ,&nbsp;Lauren Seo ,&nbsp;Derran Bedward ,&nbsp;Mei Carter ,&nbsp;Davis Carter ,&nbsp;Jacob Razzouk ,&nbsp;Omar Ramos ,&nbsp;Nathaniel Wycliffe ,&nbsp;Wayne Cheng ,&nbsp;Olumide Danisa","doi":"10.1016/j.bas.2024.104162","DOIUrl":"10.1016/j.bas.2024.104162","url":null,"abstract":"<div><h3>Introduction</h3><div>The normative relationship between lumbar intervertebral disc space height (DSH) and neuroforaminal dimensions (NFD) has yet to be defined.</div></div><div><h3>Research question</h3><div>The purpose of this study was to investigate the relationship between lumbar DSH and NFD using computed tomography (CT), accounting for influences of patient demographic and anthropometric characteristics.</div></div><div><h3>Materials and methods</h3><div>We analyzed CT imaging of 350 female and 350 male patients. Anterior, middle, and posterior DSH were measured. NFD were defined as sagittal anterior-to-posterior (AP) width, axial AP width, foraminal height, and area. Statistical analyses were performed to assess associations among DSH, NFD, and patient height, weight, body mass index, sex, and ethnicity.</div></div><div><h3>Results</h3><div>Irrespective of disc level, mean anterior, middle, and posterior DSH were 7.98 mm (n = 3500), 8.16 mm (n = 3500), and 4.09 mm (n = 3500). DSH measurements demonstrated increasing, linear trends moving caudally from L1-L2 to L5-S1, while NFD demonstrated a unimodal distribution pattern with largest NFD at L3-L4 and smallest NFD at L1-2 and L5-S1. Male patients demonstrated larger DSH compared to female patients from L1-S1. Asian patients demonstrated taller DSH across all levels L1-S1.</div></div><div><h3>Discussion and conclusion</h3><div>This study describes 38,500 CT-based L1-S1 DSH and NFD in young patients without spinal pathology. DSH follows an increasing trend moving caudally from L1-S1, while NFD demonstrate a unimodal distribution clustered at L3-L4. NFD are not moderately or strongly associated with DSH. DSH is influenced by sex and ethnicity but is not moderately or strongly influenced by patient height, weight, and BMI.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104162"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11700277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinematic limitations during stair ascent and descent in patients with adult spinal deformity","authors":"Marc Fakhoury ,&nbsp;Rami Rachkidi ,&nbsp;Karl Semaan ,&nbsp;Krystel Abi Karam ,&nbsp;Maria Saadé ,&nbsp;Elma Ayoub ,&nbsp;Celine Chaaya ,&nbsp;Ali Rteil ,&nbsp;Elena Jaber ,&nbsp;Elio Mekhael ,&nbsp;Nabil Nassim ,&nbsp;Mohamad Karam ,&nbsp;Julien Abinahed ,&nbsp;Ismat Ghanem ,&nbsp;Abir Massaad ,&nbsp;Ayman Assi","doi":"10.1016/j.bas.2024.104153","DOIUrl":"10.1016/j.bas.2024.104153","url":null,"abstract":"<div><h3>Background</h3><div>Adults with spinal deformity (ASD) are known to have spinal malalignment, which can impact their quality of life and their autonomy in daily life activities. Among these tasks, ascending and descending stairs is a common activity of daily life that might be affected.</div></div><div><h3>Research question</h3><div>What are the main kinematic alterations in ASD during stair ascent and descent?</div></div><div><h3>Methods</h3><div>112 primary ASD patients and 34 controls filled HRQoL questionnaires and underwent biplanar X-from which spino-pelvic radiographic parameters were calculated. Patients were divided into 3 groups: 44 with sagittal malalignment (ASD-Sag: PT &gt; 25°, SVA&gt;5 cm or PI-LL&gt;10°), 42 with isolated thoracic hyperkyphosis (ASD-HyperTK: TK &gt; 60°), 26 with isolated frontal spine deformity (ASD-Front: Cobb&gt;20°). All participants underwent 3D motion analysis of the whole body while ascending and descending a stair step from which kinematic waveforms were extracted.</div></div><div><h3>Results</h3><div>During stair ascent, ASD-Sag exhibited an increased thorax flexion (20 vs 5°), a decreased lumbar lordosis L1L3-L3L5 (7 vs 14°), and an increased ROM of lumbo-pelvic joint (15 vs 10°, all p &lt; 0.05), compared to controls. Similar compensations were shown while descending the stairstep. ASD-HyperTK had similar kinematic limitations as ASD-Sag but to a lesser extent. ASD-Front had normal kinematic patterns. PCS-SF36 correlated to thorax flexion (r = −0.45) and ODI was correlated to pelvic tilt ROM (r = 0.46).</div></div><div><h3>Discussion and conclusion</h3><div>ASD subjects with sagittal malalignment tend to ascend and descend stairs with increased thorax flexion, making them more prone to falls. Compensation mechanisms occur at the head and lumbo-pelvic levels to maintain balance and avoid falling forward.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104153"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The onco-functional balance in diffuse gliomas: Evolution of the concept over the past decade – And the next steps","authors":"Hugues Duffau","doi":"10.1016/j.bas.2024.104170","DOIUrl":"10.1016/j.bas.2024.104170","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104170"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sagittal changes in the dens significantly slowed after 12 years of age","authors":"Zhi-Jun Sha ,&nbsp;Sheng-Yu Fu ,&nbsp;Zhao-Rui Wang ,&nbsp;Hai-Feng Hang ,&nbsp;Ai-Bing Huang","doi":"10.1016/j.bas.2025.104233","DOIUrl":"10.1016/j.bas.2025.104233","url":null,"abstract":"<div><h3>Introduction</h3><div>The odontoid process is an important component of the upper cervical, and the process of ossification for odontoid does not cease completely until skeletal maturity.</div></div><div><h3>Research question</h3><div>The aim of the study was to obtain the inclination parameters of the dens in many healthy children and to analyze the trends and variations in the inclination of the dens.</div></div><div><h3>Material and methods</h3><div>All the CT data obtained from our hospital was reviewed for next measurement. Posterior edge of odontoid angle (PEOA), anterior edge of odontoid angle (AEOA), odontoid retroflection angle (ORA), posterior dens angulation angle (PDAA), screw insertion angle (SIA), and pB-C2 line were measured and analyzed.</div></div><div><h3>Results</h3><div>A total of 219 patients were divided into 6 groups based on age at an interval of 3 years. The mean values of PEOA and PDAA dropped dramatically with age up to the ten to twelve-year group and then decreased slightly until 18 years old. Moreover, the AEOA and ORA declined gradually from birth to adulthood. These parameters were statistical significance within different age groups. However, the SIA was largely unchanged from birth to 18 years old and appeared to be independent of age. In contrast, the PB-C2 line has a distinguish distribution, with an increase up to the nine to twelve-year age group and then gradually decreased until 18 years old.</div></div><div><h3>Discussion and conclusion</h3><div>The inclination of dens was constantly changing during pediatric growth, but the trends were different. These developmental changes slow down significantly after the age of 12 years.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104233"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Scandinavian neurotrauma committee guidelines – A retrospective study in region Örebro county","authors":"Samuel Jara Josefsson ,&nbsp;Dhanisha Trivedi ,&nbsp;Patrick Vigren ,&nbsp;András Büki","doi":"10.1016/j.bas.2025.104231","DOIUrl":"10.1016/j.bas.2025.104231","url":null,"abstract":"<div><h3>Introduction</h3><div>Traumatic Brain Injury (TBI) is a global health concern and a leading cause of trauma-related death worldwide. Computed tomography (CT) scan is the gold standard for screening for intracranial bleeding following TBI. Most cases of TBI are mild, with negative CT scans. Different instruments and guidelines are employed to better predict which patients need a CT scan and to minimise unnecessary radiation exposure and save resources. One such instrument is the Scandinavian Neurotrauma Committee guidelines.</div></div><div><h3>Research question</h3><div>To validate and examine adherence to the Scandinavian Neurotrauma Committee guidelines in Region Örebro County.</div></div><div><h3>Material and methods</h3><div>We executed a retrospective study with review of patient records and data analysis. Descriptive and comparative statistics were used, along with binary logistic regression analysis to account for confounding factors.</div></div><div><h3>Results</h3><div>A total of 505 cases were reviewed. Sensitivity of the guidelines was measured at 95% with specificity at 29%. The positive and negative predictive values were 0.77 and 0.69, respectively. A total of 17 false negative cases were found. One case required surgery, during which a chronic subdural hematoma was identified. Adherence to guidelines was 56%, with the lack of analysis of S100B primarily accounting for non-adherence. A total of 54 CT scans were performed outside of guideline indications.</div></div><div><h3>Discussion and conclusions</h3><div>The guidelines can effectively predict which patients need a CT scan. Increased adherence could potentially decrease the number of CT scans, while inclusion of older age limit as an independent rule-in law for CT scans would increase patient safety.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104231"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional outcome after surgical treatment for spontaneous intracerebral hemorrhages: Development of the HeMAtOma score","authors":"Magnus Sættem ,&nbsp;Ola Lønn Jenssen ,&nbsp;Øystein Vesterli Tveiten ,&nbsp;Stephanie Schipmann ,&nbsp;Rupavathana Mahesparan","doi":"10.1016/j.bas.2025.104240","DOIUrl":"10.1016/j.bas.2025.104240","url":null,"abstract":"<div><h3>Background</h3><div>Spontaneous intracerebral hemorrhage (sICH) is a critical medical emergency associated with significant morbidity and mortality. The role of surgical intervention in improving functional outcomes remains a subject of debate.</div></div><div><h3>Objective</h3><div>This study evaluates the functional outcomes of patients undergoing surgical treatment for sICH and identifies risk factors predictive of poor outcomes.</div></div><div><h3>Methods</h3><div>A retrospective analysis of 100 patients treated surgically for sICH at Haukeland University Hospital between 2013 and 2022 was conducted. Baseline characteristics and clinical outcomes were collected. Functional outcomes were assessed using the modified Rankin Scale (mRS) at three months post-surgery. Independent risk factors for unfavorable outcomes (mRS ≥4) were identified through logistic regression.</div></div><div><h3>Results</h3><div>The mean age was 65.5 years (56 % males). At three months, 54 % of patients had an unfavorable outcome, including a 23 % mortality rate. Independent risk factors for poor outcomes included age ≥60 years (OR 7.8, 95 % CI 1.684–36.3, p = 0.009), oral anticoagulant use (OR 10.4, 95 % CI 1.495–72.665, p = 0.018), and hemorrhage location in the basal ganglia (OR 18.5, 95 % CI 3.398–100.717, p &lt; 0.001) or motor cortex (OR 8.6, 95 % CI 2.134–34.973, p = 0.003). These factors formed the basis of a new scoring system—the HeMAtOma score—which demonstrated good discriminatory ability (AUC 0.688) for predicting outcomes.</div></div><div><h3>Conclusion</h3><div>Functional outcomes following surgical treatment for sICH remain poor in many cases. The HeMAtOma score provides a practical tool for predicting surgical outcomes, aiding clinical decision-making in emergency settings. Future prospective studies are needed to validate the score.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104240"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143769256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decompressive craniectomy following subarachnoid hemorrhage: A prospective Swedish multicenter study","authors":"Bryndís Baldvinsdóttir ,&nbsp;Erik Kronvall ,&nbsp;Elisabeth Ronne-Engström ,&nbsp;Per Enblad ,&nbsp;Paula Klurfan ,&nbsp;Johanna Eneling ,&nbsp;Peter Lindvall ,&nbsp;Helena Aineskog ,&nbsp;Steen Friðriksson ,&nbsp;Mikael Svensson ,&nbsp;Peter Alpkvist ,&nbsp;Jan Hillman ,&nbsp;Ola G. Nilsson","doi":"10.1016/j.bas.2025.104218","DOIUrl":"10.1016/j.bas.2025.104218","url":null,"abstract":"<div><h3>Introduction</h3><div>Decompressive craniectomy (DC) in patients with severe aneurysmal subarachnoid hemorrhage (aSAH) can be a life-saving procedure. The aim of this nationwide prospective study was to investigate the use of DC in aSAH patients in Sweden.</div></div><div><h3>Research question</h3><div>To explore the risk factors and functional outcome associated with DC in patients with aSAH.</div></div><div><h3>Material and methods</h3><div>Patients treated for aSAH at all neurosurgical centers in Sweden during a 3.5-year period (2014–2018) were prospectively registered. Clinical, radiological and treatment-related factors with regard to DC were analyzed using Chi-Square and logistic regression analysis. Functional outcome was assessed by the extended Glasgow outcome scale one year after the bleeding.</div></div><div><h3>Results</h3><div>During the study period, 1037 patients were treated for aSAH. Thirty-five patients (3.4%) underwent DC. At one year follow-up, 25 of these (71%) had unfavorable functional outcome. Multivariate logistic regression analysis revealed that poor clinical grade before aneurysm treatment, middle cerebral artery (MCA) aneurysm, edema on the initial computed tomography (CT), and adverse events during aneurysm occlusion were independent and significant risk factors for performing DC.</div></div><div><h3>Discussion and conclusion</h3><div>DC is relatively uncommon in aSAH patients and is related to increased risk of unfavorable outcome. However, favorable functional outcome was seen in 29% of patients with DC. Adverse events during aneurysm occlusion were significant risk factors for DC.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104218"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a weekend effect in severe traumatic brain Injury? An observational, population-based study from the Norwegian Trauma registry","authors":"Joakim Stray Andreassen ,&nbsp;Mattis A. Madsbu ,&nbsp;David Andreas Thomas Werner ,&nbsp;Clemens Weber","doi":"10.1016/j.bas.2025.104263","DOIUrl":"10.1016/j.bas.2025.104263","url":null,"abstract":"<div><h3>Introduction</h3><div>Traumatic brain injury is prevalent and with severe injury the mortality is high. The aim of this study was to explore differences in mortality rates between weekday and weekend admissions for patients with severe traumatic brain injury (TBI) in Norway based on data from the National Trauma Registry of Norway (NTR).</div></div><div><h3>Research question</h3><div>Are mortality rates higher for patients with severe traumatic brain injury admitted on weekends compared to weekdays?</div></div><div><h3>Materials and methods</h3><div>This study is an observational cohort study based on prospectively collected, population-based data from the NTR. The study period was between January 01, 2017 and December 31, 2020 and included all patients with severe TBI registered in the database.</div></div><div><h3>Results</h3><div>During the 4 years-study period 627 patients with severe TBI were identified; the median age was 53.0 years (IQR 32.0-71.0). Weekend admissions involved significantly younger patients with a median age of 50.0 years compared to a median age of 57.0 years on weekdays (p = 0.013). Overall, the 30-day mortality rate was 39 %, with higher mortality observed on weekdays compared to weekends (43 % vs. 34 %; p = 0.025). Logistic regression analysis showed that age and higher AIS head injury severity were significantly associated with 30-day mortality, while admission timing (weekend vs. weekday) showed no association.</div></div><div><h3>Discussion and conclusion</h3><div>Weekend admissions in severe TBI are frequent and involves younger patients compared to weekdays. Our study did not find a weekend effect on the mortality rate for severe TBI in Norway based on data from the NTR.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104263"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}