Brain & spine最新文献

{"title":"Radiosurgery in the treatment of Cavernous Sinus Meningiomas: A retrospective long-term outcome evaluationa","authors":"Mr Patrick Schreiner , Mr Lukas Kohlmaier , Dr. Anna Cho , Dr. Philippe Dodier , Dr. Christian Dorfer (Prof.) , Dr. Brigitte Gatterbauer , Dr. Karl Rössler (Prof.) , Dr. Christian Matula (Prof.) , Priv-Doz. Dr. Mario Mischkulnig , Dr. Josa M. Frischer (Prof.)","doi":"10.1016/j.bas.2025.104964","DOIUrl":"10.1016/j.bas.2025.104964","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104964"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Quality of Life and Mortality in Patients with Chronic Subdural Hematoma: 10-year follow-up of the TOSCAN trial.","authors":"Dr. Thomas Petutschnigg , Samuel Aschwanden , Dr. Danial Nasiri , Dr. David Bervini , Dr. Michael Murek , Dr. Levin Häni , Dr. Christopher Marvin Jesse , Dr. Werner Josef Z'Graggen , Dr. Andreas Raabe , Dr. Philippe Schucht , Dr. Johannes Goldberg","doi":"10.1016/j.bas.2025.104969","DOIUrl":"10.1016/j.bas.2025.104969","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104969"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CpG sites of WDFY3-AS2 and WDFY3 are hypermethylated in oligodendrogliomas compared to glioblastomas. Is there evidence for epigenetic regulation of a WDFY3-AS2/ WDFY3 axis?","authors":"Dr. Max Braune , Dr. Alonso-Barrantes Freer , Dr. Tim Wende , Johannes Wach (Assistant Professor) , Erdem Güresir (Professor) , Dr. Alim Emre Basaran","doi":"10.1016/j.bas.2025.104923","DOIUrl":"10.1016/j.bas.2025.104923","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104923"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Biopsy Combined with Same-session MR-guided LITT Versus Biopsy Alone in Patients with Primary Irresectable Glioblastoma: Results of a Multicenter Randomized Controlled Trial","authors":"Ms Celine Neutel , Dr. Christiaan Overduin , Dr. Anne Rijpma , Dr. Janneke Grutters (Prof.) , Dr. Gerjon Hannink , Dr. Pieter van Eijsden , Dr. Hilko Ardon , Dr. Rutger Balvers , Dr. Philip de Witt Hamer (Prof.) , Dr. Koos Hovinga , Dr. Michiel Wagemakers , Dr. Pierre Robe (Prof.) , Dr. Maroeska Rovers (Prof.) , Dr. Mark ter Laan","doi":"10.1016/j.bas.2025.104936","DOIUrl":"10.1016/j.bas.2025.104936","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104936"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote Ischemic Preconditioning To Prevent Delayed Cerebral Ischemia Due To Vasospasm In The Treatment Of Patients With Aneurysmal Subarachnoid Hemorrhage","authors":"Mrs Carolin Albrecht , Mrs. Teresa Silvestri , Maria Wostrack (Prof.) , Dr. Christian Maegerlein , Bernhard Meyer (Prof.) , Dr. Arthur Wagner , Jens Gempt (Prof.)","doi":"10.1016/j.bas.2025.104944","DOIUrl":"10.1016/j.bas.2025.104944","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104944"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transnasal adenomectomy with medial cavernous sinus wall resection for hormone-secreting pituitary adenomas: safety and short-term outcome","authors":"Dr. Michel Roethlisberger , Dr. Rachel Cottier , Dr. Simona Negoias , Jürgen Hench , Stephan Frank , Dr. Emanuel Christ , Mirjam Christ-Crain (Prof.) , Luigi Mariani (Prof.)","doi":"10.1016/j.bas.2025.104950","DOIUrl":"10.1016/j.bas.2025.104950","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104950"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting response to ventriculoperitoneal shunt in NPH with TMS-EEG neurophysiological markers","authors":"Dr. Tal Davidi , Dr. Saar Anis , Dr. Jacob Zauberman , Dr. Tzvia Fey-karmon , Dr. Adi Saar , Sharon Hassin-Baer (Prof.) , Dr. Hilla Fogel , Dr. Orit Lesman , Sharon Hassin-Baer (Prof.)","doi":"10.1016/j.bas.2025.104997","DOIUrl":"10.1016/j.bas.2025.104997","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104997"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in hemorrhage pattern on consecutive non-contrast CT scans in non-aneurysmal subarachnoid hemorrhage patients","authors":"René van den Berg ,&nbsp;Wouter Dronkers ,&nbsp;Olvert Berkhemer ,&nbsp;Arian Karbe ,&nbsp;Menno Germans ,&nbsp;W. Peter Vandertop ,&nbsp;Bart J. Emmer ,&nbsp;Dagmar Verbaan","doi":"10.1016/j.bas.2025.105603","DOIUrl":"10.1016/j.bas.2025.105603","url":null,"abstract":"<div><h3>Introduction</h3><div>The diagnosis perimesencephalic subarachnoid hemorrhage (PMSAH) is based on a specific distribution pattern within 72 h after ictus. However solid evidence is lacking for this time window with the potential risk that blood distribution can change over time, with implications for the management of these patients.</div></div><div><h3>Research question</h3><div>To study cisternal and intraventricular blood pattern changes on initial and follow-up non-contrast CT scans (NCCTs) during the first 72 h.</div></div><div><h3>Materials and methods</h3><div>This retrospective study included consecutive PMSAH and non-perimesencephalic (NPSAH) patients in whom at least two NCCTs were performed within the first 72 h. Presence and changes in the distribution of cisternal and intraventricular blood was independently assessed by three observers.</div></div><div><h3>Results</h3><div>135 patients (62 PMSAH and 73 NPSAH) were included. The distribution of SAH remained unchanged within the first 72-h in 63 (47 %) patients (PMSAH: 38 (61 %), NPSAH: 25 (39 %))(p &lt; 0.01). An increase in SAH distribution from 0 to 6 h was seen in 7/47 PMSAH (15 %) versus 24/47 (51 %) in NPSAH patients (p &lt; 0.01). A decrease in SAH distribution from 0 to 6 h was seen in 6/47 (13 %) PMSAH patients versus 2/47 (4 %) NPSAH patients (p &lt; 0.01). Between 6 and 24 h, a 72 % decrease (10/14) was only seen in NPSAH patients. The diagnosis PMSAH never changed to NPSAH or vice versa due to SAH redistribution.</div></div><div><h3>Discussion and conclusion</h3><div>Within the first 72 h after ictus, redistribution of cisternal and intraventricular blood is seen more often in NPSAH than in PMSAH patients but did not change the specific diagnosis.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 105603"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of surgical exoscope versus operating microscope in spine surgery: A Surgeon's perspective","authors":"Charlize Du Preez ,&nbsp;Jake M. McDonnell ,&nbsp;Aubrie M. Sowa ,&nbsp;Keith Synnott ,&nbsp;Marcus Timlin ,&nbsp;Seamus Morris ,&nbsp;Stacey Darwish ,&nbsp;Joseph S. Butler","doi":"10.1016/j.bas.2025.104906","DOIUrl":"10.1016/j.bas.2025.104906","url":null,"abstract":"<div><h3>Introduction</h3><div>A newly developed surgical visualization tool, the exoscope, has emerged as an alternative to the widely used operating microscope (OM). Through a qualitative survey, this study aimed to assess surgeons' perspectives on the exoscope compared to the OM, identifying its advantages, limitations, and barriers to widespread adoption.</div></div><div><h3>Research question</h3><div>What are surgeons’ perspectives of the exoscope compared to the OM?</div></div><div><h3>Materials and methods</h3><div>A 29-question survey, designed by the authors, was used to compare the exoscope and the OM. The survey addressed key comparative aspects of both systems and included demographic information about participants and their institutions. Surgeons were recruited from internationally recognized organizations of expert spinal surgeons, with invitations sent via email. Responses were submitted anonymously, ensuring unbiased and authentic data collection.</div></div><div><h3>Results</h3><div>Surgeons reported using the exoscope in a total of 1517 cases. Most surgeons found the exoscope comparable to or superior to the OM in many different parameters. 60.32 % of surgeons considered the exoscope to offer good learning opportunities, with most perceiving the learning curve as moderate (41.27 %) or mild (30.16 %). However, opinions on manoeuvrability and surgeon fatigue were divided—49.21 % found these aspects slightly better with the exoscope, a significant proportion felt they were worse. The primary drawback was its high cost, with additional concerns about ergonomics and resolution.</div></div><div><h3>Discussion and conclusion</h3><div>From a surgeon's perspective, the exoscope presents several advantages over the OM. However, further improvements are needed, and it remains uncertain whether the exoscope can fully replace the OM in surgical practice.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104906"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing the adoption of innovation in spine surgery: An international survey of AO spine network","authors":"Arun Kumar Viswanadha ,&nbsp;Luca Ambrosio ,&nbsp;Pieter-Paul A. Vergroesen ,&nbsp;Zorica Buser ,&nbsp;Hans Joerg Meisel ,&nbsp;Nancy Santesso ,&nbsp;Jason P.Y. Cheung ,&nbsp;Yabin Wu ,&nbsp;Hai V. Le ,&nbsp;Gianluca Vadalà ,&nbsp;Amit Jain ,&nbsp;Andreas K. Demetriades ,&nbsp;Sam K. Cho ,&nbsp;Patrick C. Hsieh ,&nbsp;Ashish Diwan ,&nbsp;Tim Yoon ,&nbsp;Sathish Muthu ,&nbsp;AO Spine Knowledge Forum Degenerative","doi":"10.1016/j.bas.2025.104206","DOIUrl":"10.1016/j.bas.2025.104206","url":null,"abstract":"<div><h3>Introduction</h3><div>Knowledge translation from research to clinical practice can often be challenging, and practice modification patterns among surgeons may stem from a variety of sources, including personal experience, peer influence, ongoing education, and evolving research findings.</div></div><div><h3>Research question</h3><div>This study aimed to investigate the adoption patterns amongst surgeons for newer innovations and to analyse the factors affecting the implementation of the same in clinical practice. We used the adoption of osteobiologics as a case example.</div></div><div><h3>Methods</h3><div>An international expert survey was conducted among AO Spine users and members. The survey, comprising 30 items, explored surgeons' demographics, risk aversion, and factors influencing practice change. We categorized the innovation-adoptive nature of the surgeons and scored their risk-adoptive behaviour.</div></div><div><h3>Results</h3><div>A total of 458 responses were received from surgeons across 81 countries including 433 male (95%), orthopaedic surgeons (n = 263; 57%) from university-affiliated hospitals (n = 185; 40%). Most were in the early majority phase of the innovation-adoption cycle (n = 174; 38%) with a majority in the ‘high-moderate’ risk-adoption category (n = 396; 86%). This risk adoption behaviour had a significant correlation with their appetite for innovation (r = 0.182,p=&lt;0.001). About 67.9% of respondents preferred scientific literature and conference presentations showcasing solid clinical evidence to be the most influential factor in driving change in their clinical practice. Material logistics (55%) is considered an important barrier to practice modification followed by familiarity (50%) and financial reimbursements (25%).</div></div><div><h3>Discussion &amp; conclusion</h3><div>A complex interplay exists between risk-adoptive behaviour amongst surgeons and the factors influencing a change in their clinical practice. Although most surgeons were in the early adoptive phase in accepting the innovations into their clinical practice, they were also equally noted to be risk tolerant. Hence, a successful adoption of practice-changing innovation hinges on addressing not only logistical and financial challenges but also on providing robust scientific evidence to drive the necessary change in clinical practice.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104206"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143422354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}