Brain & spine最新文献

{"title":"Posterior reversible enzephalopathie syndrome (PRES) following vestibular schwannoma surgery – Case report and review of the current theories on pathophysiology of PRES","authors":"Solveig Stadsholt ,&nbsp;Aivars Strauss ,&nbsp;Jenny Kintzel ,&nbsp;Stefan Schob ,&nbsp;Erck Elolf ,&nbsp;Mareike Rutenkröger ,&nbsp;Christian Strauss ,&nbsp;Christian Scheller ,&nbsp;Sandra Leisz ,&nbsp;Julian Prell ,&nbsp;Maximilian Scheer","doi":"10.1016/j.bas.2024.104167","DOIUrl":"10.1016/j.bas.2024.104167","url":null,"abstract":"<div><h3>Introduction</h3><div>Posterior reversible encephalopathy syndrome (PRES) is an acute form of encephalopathy. Main characteristic of this syndrome is the development of subcortical/cortical edema in the occipital lobes. The most common causes are diseases such as pre-eclampsia, autoimmune diseases, allogeneic stem cell transplantation and after treatment with immunosuppressants or cytostatics. However, PRES is also occasionally observed in connection with neurosurgical procedures, particularly in the posterior fossa in pediatric patients.</div></div><div><h3>Research question</h3><div>PRES in adults is extremely rare. After cranial surgery, the impaired consciousness caused by this syndrome may be misdiagnosed.</div></div><div><h3>Material and methods</h3><div>We present a rare case of PRES associated with vestibular schwannoma (VS) surgery and metronidazole use and have conducted a literature review.</div></div><div><h3>Results</h3><div>We found only two cases of PRES after surgery of a VS in the literature and three cases in connection with the administration of metronidazole. All cases involved women but the onset of symptoms was highly variable. The constellation of surgery and administration of metronidazole has not yet been described.</div></div><div><h3>Discussion and conclusion</h3><div>The purpose of this review is to raise awareness of a very rare complication such as PRES in this setting. Antibiotics should be chosen carefully after such an operation, as this syndrome can be triggered by certain substances.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104167"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The morphological, clinical, and prognostic factors in the management of giant anterior communicating artery aneurysms: A systematic review of cases","authors":"Roua Nasir ,&nbsp;Midhat e Zahra Naqvi ,&nbsp;Salaar Ahmed ,&nbsp;Maarij ul Hassan ,&nbsp;Rabeet Tariq ,&nbsp;Saad Akhter Khan ,&nbsp;Pia Koeskemeier ,&nbsp;Rajiv K. Khajuria ,&nbsp;Mohammad Hamza Bajwa ,&nbsp;Sajjad Muhammad","doi":"10.1016/j.bas.2025.104189","DOIUrl":"10.1016/j.bas.2025.104189","url":null,"abstract":"<div><h3>Introduction</h3><div>Giant intracranial aneurysms (GIAs) of the anterior communicating artery (AComm) are rare and challenging to treat due to their distinct angioarchitecture.</div></div><div><h3>Research question</h3><div>To review demographic, morphological, clinical, and prognostic factors in the treatment of giant AComm aneurysms to inform decision-making.</div></div><div><h3>Materials and methods</h3><div>Medline, Scopus, and Cochrane databases were searched for records examining cases diagnosed with giant AComm aneurysms. The study type, sample size, patient age, aneurysm site, aneurysm size, presenting complaints, and treatment modality were tabulated, and methodological quality was assessed. Additionally, two cases from our institution were included.</div></div><div><h3>Results</h3><div>The data from 24 retrieved records, including 45 cases (60% treated with direct clipping/clip reconstruction, 20% with surgical bypass±trapping, and 16% with endovascular/combined methods) were obtained. The mean age was 52 years with an overall male preponderance (3:1). 73% presented with symptoms; mostly visual impairment/loss and subarachnoid hemorrhage. 82% had favorable outcomes (mRS 0–2). 56% had a mean maximum diameter between 25 and 30 mm. Cases treated by direct clipping/reconstruction were primarily ruptured, while cases treated by surgical bypass/trapping were unruptured or asymptomatic. Endovascular/combined methods were utilized for only few cases.</div></div><div><h3>Discussion and conclusion</h3><div>Immediate suspicion is warranted for visual impairment with headaches in adults or seizures in the elderly. Direct clipping is the first-line treatment for ruptured cases closely followed by surgical bypass and trapping for unruptured cases. There is limited data on endovascular/combined methods. Evidence from case reports/series should be interpreted with caution. Both inter-modality and intra-modality nuances exist.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104189"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of cranial implants compared with autologous bone grafts","authors":"Vita M. Klieverik ,&nbsp;Pierre A. Robe ,&nbsp;Marvick S.M. Muradin ,&nbsp;Peter A. Woerdeman","doi":"10.1016/j.bas.2025.104217","DOIUrl":"10.1016/j.bas.2025.104217","url":null,"abstract":"<div><h3>Introduction</h3><div>Autografts are considered more cost-effective than cranial implants due to the use of the patient's own bone. However, autografts are associated with a higher revision surgery rate because of their intrinsic risk of resorption. As revision surgeries imply additional hospital stays and therefore higher costs, autografts may be less cost-effective than cranial implants.</div></div><div><h3>Research question</h3><div>To analyze the cost-effectiveness of cranial implants compared with autografts.</div></div><div><h3>Material and methods</h3><div>We performed a retrospective cohort study of patients who underwent cranioplasty between 2014 and 2020. We collected data on the costs of cranioplasty using each patient's diagnosis and treatment combination (DBC) code. We used the incremental cost-effectiveness ratio (ICER) to assess cost-effectiveness, which was calculated as the ratio of incremental cost and incremental effect of using a cranial implant instead of an autograft.</div></div><div><h3>Results</h3><div>A total of 168 patients were included (mean age 43.0 ± 20.0 years). The median cost of the first cranioplasty procedure was €6249.37 (IQR €5250.64 – €8551.36) for cranial implants and €6261.36 (IQR €5189.14 – €7792.10) for autografts (p = 0.094). The median total cost of all health care related to the cranioplasty procedure was €6460.64 (IQR €6039.68 – €9533.03) for cranial implants and €12,075.01 (IQR €6409.63 – €16,420.71) for autografts (p &lt; 0.001). The ICER of cranial implants compared with autografts was –€7663.22 per revision surgery avoided.</div></div><div><h3>Discussion and conclusion</h3><div>This study found that the use of cranial implants is at a lower cost and more clinically effective than the use of autologous bone grafts.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104217"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the learning curve and operative time of interlaminar and transforaminal endoscopic lumbar discectomy","authors":"Youssef Jamaleddine ,&nbsp;Ahmad Haj Hussein ,&nbsp;Mohamad Omar Honeine ,&nbsp;Elio Daccache ,&nbsp;Sarah El Hajjar ,&nbsp;Ramzi Moucharafieh ,&nbsp;Nizar Natout ,&nbsp;Mohammad Badra","doi":"10.1016/j.bas.2025.104225","DOIUrl":"10.1016/j.bas.2025.104225","url":null,"abstract":"<div><h3>Introduction</h3><div>Lumbar disc herniation is common in spine surgery, and endoscopic lumbar discectomy (ELD) offers a minimally invasive alternative with reduced complications. However, the learning curve of ELD, particularly between interlaminar and transforaminal techniques, remains a challenge.</div></div><div><h3>Research question</h3><div>To determine the learning curve for both interlaminar and transforaminal ELD in terms of operative time, and analyze factors that affect it.</div></div><div><h3>Materials and methods</h3><div>Single-center retrospective study of 376 patients who underwent ELD between January 2013 and March 2024. In the cohort, 319 were in the interlaminar group and 57 in the transforaminal group. The learning curves were analyzed by CUSUM. The data regarding surgical technique, operative time, and postoperative outcome were analyzed.</div></div><div><h3>Results</h3><div>The learning curve reached a plateau at 50 cases for the interlaminar technique and 23 cases for the transforaminal technique. Operative time was significantly lower for the transforaminal approach compared to the interlaminar approach: 69.18 ± 28.85 min versus 78.71 ± 28.86 min, p = 0.022. A second learning curve could not be demonstrated for the interlaminar approach in the long term. Operative time was influenced variably by factors such as age, gender, and level of herniated disc between the two techniques.</div></div><div><h3>Discussion and conclusion</h3><div>Both the interlaminar and transforaminal ELD are minimally invasive techniques with different learning curves. The transforaminal approach shows a steeper learning curve and shorter operative time. The interlaminar approach did not show a second learning curve in the long term.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104225"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic subdural hematoma with mild to moderate symptoms: The effect of initial treatment approach on clinical outcome","authors":"Merijn Foppen ,&nbsp;Roger Lodewijkx ,&nbsp;Mariam Slot ,&nbsp;William P. Vandertop ,&nbsp;Dagmar Verbaan","doi":"10.1016/j.bas.2025.104219","DOIUrl":"10.1016/j.bas.2025.104219","url":null,"abstract":"<div><h3>Background</h3><div>The effect of a conservative (wait-and-watch) approach in chronic subdural hematoma (cSDH) patients with mild to moderate symptoms, is poorly studied. Surgical evacuation is effective, but inherently carries the risk of surgical or anesthetic complications.</div></div><div><h3>Research question</h3><div>To assess the effect of conservative or operative (burrhole craniostomy) treatment on clinical outcome, in cSDH patients with mild to moderate symptoms.</div></div><div><h3>Methods</h3><div>This single center, retrospective cohort study included 444 cSDH patients with a Markwalder Grading Scale score 1 or 2, treated between 2012 and 2022. The primary outcomes were complication rate, length of hospital stay and 30-days’ mortality. The results were analyzed using both intention-to-treat and as-treated approaches. Propensity score techniques were applied to adjust for clinical and radiological baseline differences.</div></div><div><h3>Results</h3><div>Of the 114 conservatively treated patients, 49 (43%) crossed-over to surgery. The 330 remaining patients were treated surgically. In the intention-to-treat and as-treated analysis, initial surgery was associated with a higher complication rate (OR 2.02, 95% CI 1.04–3.94; OR 2.87, 95% CI 1.04–7.91) and longer hospital stay (β 2.34, 95% CI 0.15–4.52; β 6.62, 95% CI 3.60–9.64). Conservative treatment was associated with higher 30-day mortality (as-treated OR 0.19, 95% CI 0.06–0.66, favoring surgery), but this was unrelated to cSDH.</div></div><div><h3>Conclusion</h3><div>In this selected cohort of cSDH patients with mild to moderate symptoms, a conservative approach was associated with less complications and hospital stay. For these patients, a ‘conservative treatment first’ regimen may therefore be considered. Corroboration in a prospective cohort with neurological and functional outcomes is warranted.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104219"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143535132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatoid arthritis-associated cervical spine deformity and flares in disease activity","authors":"Anna B. Lebouille-Veldman ,&nbsp;Dylan Spenkelink ,&nbsp;Tom W.J. Huizinga ,&nbsp;Carmen L.A. Vleggeert-Lankamp","doi":"10.1016/j.bas.2025.104235","DOIUrl":"10.1016/j.bas.2025.104235","url":null,"abstract":"<div><h3>Introduction</h3><div>While rheumatoid arthritis (RA)-associated cervical spine deformity seems to be less prevalent following the introduction of the medication regimen to suppress inflammation in RA in an early stage, identifying patients at risk for atlantoaxial subluxation (AAS) or subaxial subluxation (SAS) remains challenging.</div></div><div><h3>Research question</h3><div>The aim of the current study is to evaluate the association of the frequency of flares in systemic disease activity (DAS) and RA-associated cervical spine deformity.</div></div><div><h3>Materials and methods</h3><div>This is a sub-analysis of the BeSt Study, where patients were treated to target DAS≤2.4. Lateral X-rays at 5- and 10-years follow-up were assessed for AAS and SAS.</div></div><div><h3>Results</h3><div>Of 272 RA patients with radiographs of cervical spine that were included, 108 (40 %) had cervical deformity (AAS and/or SAS &gt;2 mm). Although the number of patients with 3 or more flares was low, the majority of these patients did not demonstrate cervical spine deformity. After adjustment for the potential confounders age, gender, ACPA-status and RF-status, the presence of 3 or more flares was associated with a non-significant OR of 0.338 (95 % CI: 0.095–1.207) for the presence of RA-associated cervical spine deformity after 10 years.</div></div><div><h3>Discussion and conclusion</h3><div>A trend towards less RA-associated cervical deformity in patients with more flares was discerned, though no statistically significant differences could be established. It is hypothesized that the occurrence of a flare leads to an increase in medication, which may in turn protect the cervical spine from developing deformities. Future studies should more in detail explore the effect of medication on cervical deformity.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104235"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143680257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing spine surgery: Evaluating the potential for full robotic automation","authors":"Nicolás Samprón ,&nbsp;Jesus Lafuente ,&nbsp;Jorge Presa-Alonso ,&nbsp;Marcel Ivanov ,&nbsp;Roger Hartl ,&nbsp;Florian Ringel","doi":"10.1016/j.bas.2025.104232","DOIUrl":"10.1016/j.bas.2025.104232","url":null,"abstract":"<div><h3>Introduction</h3><div>The use of robotic systems in spine surgery is expanding, with growing interest in the potential for full automation. This review explores current robotic technologies, their limitations, and future automation possibilities, focusing on technical and practical aspects.</div></div><div><h3>Research question</h3><div>What are the current capabilities and limitations of robotic systems in spine surgery, and how might advancements in tracking technologies facilitate a transition toward greater automation?</div></div><div><h3>Material and methods</h3><div>A narrative review of literature on robotic spine surgery systems was conducted, analyzing benefits, accuracy, limitations, and innovations necessary for full automation. Focus was placed on trajectory-guiding technologies, such as optical tracking and alternative tracking methods.</div></div><div><h3>Results</h3><div>Current robotic systems (e.g., Cirq®, Mazor X™, ExcelsiusGPS™) assist in trajectory guidance but lack autonomy. Optical tracking systems present challenges, such as obstruction vulnerability and inaccuracies in complex constructs. Conversely, encoder-based tracking demonstrated superior accuracy, offering a promising pathway toward increased automation. The potential advantages of robotics over conventional navigation, including their nature and clinical relevance, remain a topic of active discussion. However, the inherent complexity of spine surgery and the critical role of human decision-making remain substantial barriers.</div></div><div><h3>Discussion and conclusion</h3><div>While full automation in robotic spine surgery is not yet attainable, advancements in tracking technologies point to a future of enhanced robot-surgeon collaboration, which could optimize clinical outcomes and improve procedural safety.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104232"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143680258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior transpetrosal approach to a suprasellar retroinfundibular pituicytoma: A case report and comprehensive literature review","authors":"Tancredo Alcântara ,&nbsp;Jerold Justo ,&nbsp;Tingting Jiang ,&nbsp;Rosaria Abbritti ,&nbsp;Stefan Lieber ,&nbsp;Thibault Passeri ,&nbsp;Marc-Antoine Labeyrie ,&nbsp;Sébastien Froelich","doi":"10.1016/j.bas.2025.104239","DOIUrl":"10.1016/j.bas.2025.104239","url":null,"abstract":"<div><h3>Introduction</h3><div>Pituicytomas are rare benign glial neoplasms (WHO grade I) located in the sellar or suprasellar regions, arising from the neurohypophysis and infundibular area. They typically present with symptoms due to the slow growth of the tumor, including hormonal changes, visual impairment, and headaches.</div></div><div><h3>Research question</h3><div>This case report evaluates the effectiveness of the posterior transpetrosal approach for the resection of a retroinfundibular suprasellar pituicytoma, focusing on preserving pituitary function and minimizing surgical risks.</div></div><div><h3>Material and methods</h3><div>We present a 59-year-old female with a pituicytoma diagnosed by MRI and digital subtraction angiography (DSA). Preoperative embolization was performed to reduce the tumor’s vascularity. The patient underwent a left posterior transpetrosal approach for tumor resection, with key surgical steps focusing on preserving the pituitary stalk, optic chiasm, and perforating vessels.</div></div><div><h3>Results</h3><div>The posterior transpetrosal approach provided excellent exposure, enabling near-total resection of the tumor. The patient had no new neurological deficits postoperatively, and follow-up MRI at 6 months showed no tumor recurrence.</div></div><div><h3>Discussion and conclusion</h3><div>This case demonstrates the safety and efficacy of the posterior transpetrosal approach for pituicytoma resection. The approach allowed for optimal visualization and preservation of critical structures, particularly the pituitary stalk, leading to a favorable clinical outcome. Our findings, supported by a literature review, suggest that this technique is a valuable option for tumors in retroinfundibular and suprasellar locations.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104239"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143680313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The acute phase management of traumatic spinal cord injury (tSCI) with polytrauma: A narrative review.","authors":"Edoardo Picetti, Nicolò Marchesini, Walter L Biffl, Susan E Biffl, Fausto Catena, Raul Coimbra, Michael G Fehlings, Wilco C Peul, Chiara Robba, Michele Salvagno, Fabio S Taccone, Andreas K Demetriades","doi":"10.1016/j.bas.2024.104146","DOIUrl":"10.1016/j.bas.2024.104146","url":null,"abstract":"<p><strong>Introduction: </strong>Traumatic spinal cord injury (tSCI) is frequently observed in polytrauma patients.</p><p><strong>Research question: </strong>What is the optimal strategy to manage tSCI in the setting of polytrauma?</p><p><strong>Material and methods: </strong>This narrative review focuses on: 1) extraspinal damage control surgery and resuscitation, 2) the perioperative protection of the injured spine during emergency surgery, 3) imaging and timing of spinal surgery in polytrauma, 4) early interventions for skin, bowel and bladder, and 5) the multidisciplinary approach to tSCI polytrauma patients.</p><p><strong>Results: </strong>Damage control resuscitation (DCR) and damage control surgery (DCS), aim to prevent/correct post-traumatic physiological derangements to minimize bleeding until definitive hemostasis is achieved. Spinal protection during emergency surgery is of paramount importance to reduce secondary insults to the injured spine. Imaging, especially magnetic resonance imaging (MRI), is useful for decision-making regarding surgical management of the injured spine. Early decompressive surgery (within 24 h from trauma) is associated with better neurological outcomes. Early consultation with a physical medicine and rehabilitation physician is beneficial to optimize recovery. A close collaboration between different medical specialties involved in the early management of tSCI patients with polytrauma is advisable to improve outcome.</p><p><strong>Discussion and conclusion: </strong>This narrative review aims to collate basic knowledge regarding acute phase management of tSCI patients in the context of polytrauma. More evidence and data form well-powered studies are necessary in this setting.</p>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"4 ","pages":"104146"},"PeriodicalIF":1.9,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to Editor: Fluorescence-guided surgery for high-grade gliomas.","authors":"Diogo Roque, Nida Kalyal, Yasir A Chowdhury, Ali Elhag, Matthew Elliot, Keyoumars Ashkan, Francesco Vergani, Ranjeev Bhangoo, José Pedro Lavrador","doi":"10.1016/j.bas.2024.104147","DOIUrl":"10.1016/j.bas.2024.104147","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"4 ","pages":"104147"},"PeriodicalIF":1.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}