Brain & NeuroRehabilitation最新文献

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Classification and Diagnosis of Adult Glioma: A Scoping Review. 成人胶质瘤的分类和诊断:范围综述。
Brain & NeuroRehabilitation Pub Date : 2022-11-22 eCollection Date: 2022-11-01 DOI: 10.12786/bn.2022.15.e23
Yoon Hwan Byun, Chul-Kee Park
{"title":"Classification and Diagnosis of Adult Glioma: A Scoping Review.","authors":"Yoon Hwan Byun, Chul-Kee Park","doi":"10.12786/bn.2022.15.e23","DOIUrl":"10.12786/bn.2022.15.e23","url":null,"abstract":"<p><p>Gliomas are primary central nervous system tumors that arise from glial progenitor cells. Gliomas have been classically classified morphologically based on their histopathological characteristics. However, with recent advances in cancer genomics, molecular profiles have now been integrated into the classification and diagnosis of gliomas. In this review article, we discuss the clinical features, imaging findings, and molecular profiles of adult-type diffuse gliomas based on the new 2021 World Health Organization Classifications of Tumors of the central nervous system.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e23"},"PeriodicalIF":0.0,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/1e/bn-15-e23.PMC9833487.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9229765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gene Expression Profile Changes in the Stimulated Rat Brain Cortex After Repetitive Transcranial Magnetic Stimulation. 重复经颅磁刺激后大鼠大脑皮层基因表达谱的变化。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e27
Wonjae Hwang, Joong Kyung Choi, Moon Suk Bang, Woong-Yang Park, Byung-Mo Oh
{"title":"Gene Expression Profile Changes in the Stimulated Rat Brain Cortex After Repetitive Transcranial Magnetic Stimulation.","authors":"Wonjae Hwang,&nbsp;Joong Kyung Choi,&nbsp;Moon Suk Bang,&nbsp;Woong-Yang Park,&nbsp;Byung-Mo Oh","doi":"10.12786/bn.2022.15.e27","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e27","url":null,"abstract":"<p><p>Repetitive transcranial magnetic stimulation (rTMS) is gaining popularity as a research tool in neuroscience; however, little is known about its molecular mechanisms of action. The present study aimed to investigate the rTMS-induced transcriptomic changes; we performed microarray messenger RNA, micro RNA, and integrated analyses to explore these molecular events. Eight adult male Sprague-Dawley rats were subjected to a single session of unilateral rTMS at 1 Hz (n = 4) or sham (n = 4). The left hemisphere was stimulated for 20 minutes. To evaluate the cumulative effect of rTMS, eight additional rats were assigned to the 1-Hz (n = 4) or sham (n = 4) rTMS groups. The left hemisphere was stimulated for 5 consecutive days using the same protocol. Microarray analysis revealed differentially expressed genes in the rat cortex after rTMS treatment. The overrepresented gene ontology categories included the positive regulation of axon extension, axonogenesis, intracellular transport, and synaptic plasticity after repeated sessions of rTMS. A single session of rTMS primarily induced changes in the early genes, and several miRNAs were significantly related to the mRNAs. Future studies are required to validate the functional significance of selected genes and refine the therapeutic use of rTMS.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e27"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/95/bn-15-e27.PMC9833481.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9214093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Erratum: Assessment of Upper Extremity Function in People With Stroke Based on the Framework of the ICF: A Narrative Review. 勘误:基于ICF框架的中风患者上肢功能评估:叙述性回顾。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e33
Hanna Kim, Joon-Ho Shin
{"title":"Erratum: Assessment of Upper Extremity Function in People With Stroke Based on the Framework of the ICF: A Narrative Review.","authors":"Hanna Kim,&nbsp;Joon-Ho Shin","doi":"10.12786/bn.2022.15.e33","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e33","url":null,"abstract":"<p><p>[This corrects the article e16 in vol. 15.].</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e33"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/b5/bn-15-e33.PMC9833486.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10644525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Cortical Cerebral Microinfarcts on Functional Outcomes in Patients With Ischemic Stroke. 脑皮质微梗死对缺血性脑卒中患者功能预后的影响
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e30
Jeong A Ham, Yoon Jeong Jeong, Min Kyeong Ma, Hyun Im Moon
{"title":"The Impact of Cortical Cerebral Microinfarcts on Functional Outcomes in Patients With Ischemic Stroke.","authors":"Jeong A Ham,&nbsp;Yoon Jeong Jeong,&nbsp;Min Kyeong Ma,&nbsp;Hyun Im Moon","doi":"10.12786/bn.2022.15.e30","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e30","url":null,"abstract":"<p><p>The present study examined cortical cerebral microinfarcts (CMIs) on a 3T magnetic resonance imaging and investigated the impact of CMIs on the comprehensive functional outcomes during the post-stroke rehabilitation period. Patients with acute phase of first-ever ischemic stroke were retrospectively recruited (n = 62) and divided into 2 groups with and without CMIs. Clinical parameters including age, sex, stroke lesion laterality, location, the National Institutes of Health Stroke Scale score, as well as history of hypertension, dyslipidemia, diabetes mellitus, and smoking were obtained. Functional outcomes were assessed twice at baseline and one month later with the Korean version of the Mini-Mental State Examination, the Berg balance scale (BBS), and the functional independence measure. Partial correlation and multiple linear regression analyses were used to examine the relationship between the presence of CMIs and the change in functional outcomes. At least one CMI was reported in 27 patients, who were older (p = 0.043). The presence of CMIs was significantly associated with functional impairment in all 3 functional outcomes, after controlling for confounding factors (p < 0.05). CMIs might contribute to poor functional outcomes during the post-stroke rehabilitation period. These results suggest that CMIs should be considered when establishing rehabilitation treatment strategies or making a prognosis.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e30"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ce/81/bn-15-e30.PMC9833484.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9214096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Peduncular Hallucinosis 7 Months After Pontine Hemorrhage With Hypertrophic Olivary Degeneration: A Case Report. 脑桥出血并发肥厚性橄榄变性7个月后出现足跖幻觉1例。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e31
Woosik Choi, So Jung Lee, Sung-Hwa Ko, Yong-Il Shin, Ji Hong Min
{"title":"Peduncular Hallucinosis 7 Months After Pontine Hemorrhage With Hypertrophic Olivary Degeneration: A Case Report.","authors":"Woosik Choi,&nbsp;So Jung Lee,&nbsp;Sung-Hwa Ko,&nbsp;Yong-Il Shin,&nbsp;Ji Hong Min","doi":"10.12786/bn.2022.15.e31","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e31","url":null,"abstract":"<p><p>Peduncular hallucinosis is a rare type of hallucination, wherein patients see colorful and vivid images. It usually appears after damage to the midbrain, pons, or thalamus. We report the case of a 56-year-old man with peduncular hallucinosis after conservative care for spontaneous pontine hemorrhage, 7 months prior to presentation. He was treated with atypical antipsychotics, which resolved the symptoms. We suggest that it is important to consider peduncular hallucinosis in patients after injuries in subcortical areas and the brainstem. Additionally, we found changes in the hypertrophic olivary degeneration using magnetic resonance imaging, and we suggest the possibility of their correlation with peduncular hallucinosis.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e31"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b1/84/bn-15-e31.PMC9833485.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9263078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Adult Gliomas: A Current Update. 成人胶质瘤的治疗:最新进展。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e24
Joo Ho Lee, Chan Woo Wee
{"title":"Treatment of Adult Gliomas: A Current Update.","authors":"Joo Ho Lee,&nbsp;Chan Woo Wee","doi":"10.12786/bn.2022.15.e24","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e24","url":null,"abstract":"<p><p>Gliomas are the most common type of primary brain tumor in adults. Glioma treatment requires a multidisciplinary approach involving surgery, radiotherapy, and chemotherapy. Multiple trials have been conducted to establish the appropriate choice of treatment to achieve long-term survival and better quality of life. This review provides up-to-date evidence regarding treatment strategies for gliomas.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e24"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/11/bn-15-e24.PMC9833488.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The Relationship Between Visuoconstructive Abilities and Language Performance in Patients With Aphasia After Stroke. 脑卒中后失语症患者视觉建构能力与语言表现的关系。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e28
Yu Mi Hwang, Hoyoung Yi, Jae-Ik Lee, Sung-Bom Pyun
{"title":"The Relationship Between Visuoconstructive Abilities and Language Performance in Patients With Aphasia After Stroke.","authors":"Yu Mi Hwang,&nbsp;Hoyoung Yi,&nbsp;Jae-Ik Lee,&nbsp;Sung-Bom Pyun","doi":"10.12786/bn.2022.15.e28","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e28","url":null,"abstract":"<p><p>This study aimed to investigate the visuoconstructive abilities and the relationship between visuoconstructive function and language performance in aphasic patients. Right-handed 24 aphasic patients (males 14, females 10) with at least 3 months post-stroke and 32 age-matched healthy controls participated in this study. Visuoconstructive function was assessed by 3 levels of task difficulty: simple (drawing objects), intermediate (clock drawing), and complex (copy subtest of Rey complex figure test and block construction). Aphasic patients were divided into 3 sub-groups (mild, moderate to severe, and very severe group) according to severity of aphasia and compared with the control group, respectively. We analyzed the relation all levels of visuoconstructive tasks to aphasia quotient (AQ) and sub-domain scores of K-WAB. Moderate to severe aphasia group demonstrated no significant differences in scores of simple drawing objects compared to controls, but clock drawing, Rey complex figure copy and block design showed significantly decreased scores. Very severe group showed significantly lower scores in all levels of visuoconstructive tasks than the control. Correlation between all levels of visuoconstructive tasks except drawing objects and AQ were found to be statistically significant. Among the tasks, the clock drawing test revealed the highest correlation with language performance. Visuoconstructive abilities varied according to the severity of aphasia and the level of visuoconstructive tasks. Therefore, a thorough individual assessment of visuoconstructive function is needed to plan and predict the treatment and prognosis of aphasia and the clock drawing test may be a useful screening tool to evaluate this function.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e28"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/a3/bn-15-e28.PMC9833482.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain Tumor Rehabilitation: Symptoms, Complications, and Treatment Strategy. 脑肿瘤康复:症状、并发症和治疗策略。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e25
Jinyoung Park, Yoon Ghil Park
{"title":"Brain Tumor Rehabilitation: Symptoms, Complications, and Treatment Strategy.","authors":"Jinyoung Park,&nbsp;Yoon Ghil Park","doi":"10.12786/bn.2022.15.e25","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e25","url":null,"abstract":"<p><p>Brain tumors are receiving increasing attention in cancer rehabilitation due to their high rate of neurological deterioration. Motor dysfunction, cognitive deterioration, and emotional problems are commonly present in patients with brain tumors. Other medical complications, such as seizures, headache, and dysphagia are also common. An individualized multidisciplinary rehabilitation intervention is necessary to treat functional impairment due to the tumor itself and/or treatment-related dysfunction. Herein, we discuss rehabilitation treatment strategies in relation to the neurological and functional complications that commonly occur in patients with brain tumors.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e25"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/88/bn-15-e25.PMC9833490.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9229769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Use of Machine Learning in Stroke Rehabilitation: A Narrative Review. 机器学习在中风康复中的应用:述评。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e26
Yoo Jin Choo, Min Cheol Chang
{"title":"Use of Machine Learning in Stroke Rehabilitation: A Narrative Review.","authors":"Yoo Jin Choo,&nbsp;Min Cheol Chang","doi":"10.12786/bn.2022.15.e26","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e26","url":null,"abstract":"<p><p>A narrative review was conducted of machine learning applications and research in the field of stroke rehabilitation. The machine learning models commonly used in medical research include random forest, logistic regression, and deep neural networks. Convolutional neural networks (CNNs), a type of deep neural network, are typically used for image analysis. Machine learning has been used in stroke rehabilitation to predict recovery of motor function using a large amount of clinical data as input. Recent studies on predicting motor function have trained CNN models using magnetic resonance images as input data together with clinical data to increase the accuracy of motor function prediction models. Additionally, a model interpreting videofluoroscopic swallowing studies was developed and investigated. In the future, we anticipate that machine learning will be actively used to treat stroke patients, such as predicting the occurrence of depression and the recovery of language, cognitive, and sensory function, as well as prescribing appropriate rehabilitation treatments.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e26"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/81/bn-15-e26.PMC9833483.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9214094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Progressive Multifocal Leukoencephalopathy With Hyper-IgM Syndrome in a 6-Year-Old Boy. 进行性多灶性白质脑病伴高igm综合征1例6岁男孩。
Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e32
Han Su Kim, Hyun Woo Cho, Yeon Jun Kim, Soo Jin Jung
{"title":"Progressive Multifocal Leukoencephalopathy With Hyper-IgM Syndrome in a 6-Year-Old Boy.","authors":"Han Su Kim,&nbsp;Hyun Woo Cho,&nbsp;Yeon Jun Kim,&nbsp;Soo Jin Jung","doi":"10.12786/bn.2022.15.e32","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e32","url":null,"abstract":"<p><p>Hyper-immunoglobulin (Ig) M syndrome is a congenital immunodeficiency disorder characterized by increased serum IgM with low serum IgG, IgA, and IgE. We report the case of a 6-year-old boy with hyper-IgM syndrome as an underlying disease who showed progressive multifocal leukoencephalopathy findings on brain magnetic resonance imaging after visiting the hospital due to left upper extremity muscle weakness, gait disturbance, and speech impairment. At the time of hospitalization, he was treated with steroids and intravenous immunoglobulin, and his condition improved somewhat, but 6 months later, he visited the hospital with rapid deterioration.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e32"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/f1/bn-15-e32.PMC9833491.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9229762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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