Brain & NeuroRehabilitation最新文献_第7页

Effects of Home Based Serious Game Training (Brain Talk™) in the Elderly With Mild Cognitive Impairment: Randomized, a Single-Blind, Controlled Trial. 基于家庭的严肃游戏训练(Brain Talk™)对轻度认知障碍老年人的影响:随机、单盲、对照试验。

Brain & NeuroRehabilitation Pub Date : 2023-03-01 DOI: 10.12786/bn.2023.16.e4

Eun Hee Lim, Da-Sol Kim, Yu-Hui Won, Sung-Hee Park, Jeong-Hwan Seo, Myoung-Hwan Ko, Gi-Wook Kim

{"title":"Effects of Home Based Serious Game Training (Brain Talk™) in the Elderly With Mild Cognitive Impairment: Randomized, a Single-Blind, Controlled Trial.","authors":"Eun Hee Lim, Da-Sol Kim, Yu-Hui Won, Sung-Hee Park, Jeong-Hwan Seo, Myoung-Hwan Ko, Gi-Wook Kim","doi":"10.12786/bn.2023.16.e4","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e4","url":null,"abstract":"Mild cognitive impairment (MCI) increases with aging society. Serious games may be effective in improving cognitive function in patients with MCI; however, research on their effects remains insufficient. This study aimed to confirm the efficacy and safety of cognitive rehabilitation training using a serious game (Brain Talk™) for the elderly with MCI. Twenty-four elderly individuals with MCI were randomized into study and control groups. The study group received 12 training sessions (30 min/session, 3 times/week), whereas the control group did not receive training. Blinded evaluations were conducted before and after the training and four weeks after the training. The primary outcome measures were the Korean Mini-Mental State Examination (K-MMSE) and K-MoCA (Korean Montreal Cognitive Assessment). Secondary outcome measures were the Semantic Verbal Fluency Task (SVFT), Trail-Making Test-B, and 2-back test. In the study group, the K-MMSE, K-MoCA, and SVFT scores after finishing the training and 4 weeks after training showed a significant increase; however, there was no significant change in the control group. No significant differences were observed between the two groups. Cognitive function significantly improved in the study group after training. Home-based serious games are considered helpful in improving cognitive function.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d5/2b/bn-16-e4.PMC10079474.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9272572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Urodynamic Study in Multiple System Atrophy: A Retrospective Observational Study. 多系统萎缩的尿动力学研究:一项回顾性观察研究。

Brain & NeuroRehabilitation Pub Date : 2023-03-01 DOI: 10.12786/bn.2023.16.e7

Woosik Choi, Kyoung-Hyeon Cha, Haeri Park, Sungchul Huh, Sung-Hwa Ko, Yong-Il Shin, Ji Hong Min

引用次数: 0

Letter to the Editor: Effects of Cognitive-Physical Dual-Task Training on Executive Function and Activity in the Prefrontal Cortex of Older Adults with Mild Cognitive Impairment. 致编辑的信:认知-物理双任务训练对轻度认知障碍老年人前额皮质执行功能和活动的影响。

Brain & NeuroRehabilitation Pub Date : 2023-03-01 DOI: 10.12786/bn.2023.16.e5

Thajus Asirvatham

引用次数: 1

Classification and Diagnosis of Adult Glioma: A Scoping Review. 成人胶质瘤的分类和诊断：范围综述。

Brain & NeuroRehabilitation Pub Date : 2022-11-22 eCollection Date: 2022-11-01 DOI: 10.12786/bn.2022.15.e23

Yoon Hwan Byun, Chul-Kee Park

引用次数: 0

Gene Expression Profile Changes in the Stimulated Rat Brain Cortex After Repetitive Transcranial Magnetic Stimulation. 重复经颅磁刺激后大鼠大脑皮层基因表达谱的变化。

Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e27

Wonjae Hwang, Joong Kyung Choi, Moon Suk Bang, Woong-Yang Park, Byung-Mo Oh

{"title":"Gene Expression Profile Changes in the Stimulated Rat Brain Cortex After Repetitive Transcranial Magnetic Stimulation.","authors":"Wonjae Hwang, Joong Kyung Choi, Moon Suk Bang, Woong-Yang Park, Byung-Mo Oh","doi":"10.12786/bn.2022.15.e27","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e27","url":null,"abstract":"Repetitive transcranial magnetic stimulation (rTMS) is gaining popularity as a research tool in neuroscience; however, little is known about its molecular mechanisms of action. The present study aimed to investigate the rTMS-induced transcriptomic changes; we performed microarray messenger RNA, micro RNA, and integrated analyses to explore these molecular events. Eight adult male Sprague-Dawley rats were subjected to a single session of unilateral rTMS at 1 Hz (n = 4) or sham (n = 4). The left hemisphere was stimulated for 20 minutes. To evaluate the cumulative effect of rTMS, eight additional rats were assigned to the 1-Hz (n = 4) or sham (n = 4) rTMS groups. The left hemisphere was stimulated for 5 consecutive days using the same protocol. Microarray analysis revealed differentially expressed genes in the rat cortex after rTMS treatment. The overrepresented gene ontology categories included the positive regulation of axon extension, axonogenesis, intracellular transport, and synaptic plasticity after repeated sessions of rTMS. A single session of rTMS primarily induced changes in the early genes, and several miRNAs were significantly related to the mRNAs. Future studies are required to validate the functional significance of selected genes and refine the therapeutic use of rTMS.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e27"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/95/bn-15-e27.PMC9833481.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9214093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Erratum: Assessment of Upper Extremity Function in People With Stroke Based on the Framework of the ICF: A Narrative Review. 勘误:基于ICF框架的中风患者上肢功能评估:叙述性回顾。

Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e33

Hanna Kim, Joon-Ho Shin

引用次数: 0

The Impact of Cortical Cerebral Microinfarcts on Functional Outcomes in Patients With Ischemic Stroke. 脑皮质微梗死对缺血性脑卒中患者功能预后的影响

Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e30

Jeong A Ham, Yoon Jeong Jeong, Min Kyeong Ma, Hyun Im Moon

{"title":"The Impact of Cortical Cerebral Microinfarcts on Functional Outcomes in Patients With Ischemic Stroke.","authors":"Jeong A Ham, Yoon Jeong Jeong, Min Kyeong Ma, Hyun Im Moon","doi":"10.12786/bn.2022.15.e30","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e30","url":null,"abstract":"The present study examined cortical cerebral microinfarcts (CMIs) on a 3T magnetic resonance imaging and investigated the impact of CMIs on the comprehensive functional outcomes during the post-stroke rehabilitation period. Patients with acute phase of first-ever ischemic stroke were retrospectively recruited (n = 62) and divided into 2 groups with and without CMIs. Clinical parameters including age, sex, stroke lesion laterality, location, the National Institutes of Health Stroke Scale score, as well as history of hypertension, dyslipidemia, diabetes mellitus, and smoking were obtained. Functional outcomes were assessed twice at baseline and one month later with the Korean version of the Mini-Mental State Examination, the Berg balance scale (BBS), and the functional independence measure. Partial correlation and multiple linear regression analyses were used to examine the relationship between the presence of CMIs and the change in functional outcomes. At least one CMI was reported in 27 patients, who were older (p = 0.043). The presence of CMIs was significantly associated with functional impairment in all 3 functional outcomes, after controlling for confounding factors (p < 0.05). CMIs might contribute to poor functional outcomes during the post-stroke rehabilitation period. These results suggest that CMIs should be considered when establishing rehabilitation treatment strategies or making a prognosis.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e30"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ce/81/bn-15-e30.PMC9833484.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9214096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Peduncular Hallucinosis 7 Months After Pontine Hemorrhage With Hypertrophic Olivary Degeneration: A Case Report. 脑桥出血并发肥厚性橄榄变性7个月后出现足跖幻觉1例。

Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e31

Woosik Choi, So Jung Lee, Sung-Hwa Ko, Yong-Il Shin, Ji Hong Min

引用次数: 0

Treatment of Adult Gliomas: A Current Update. 成人胶质瘤的治疗:最新进展。

Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e24

Joo Ho Lee, Chan Woo Wee

引用次数: 3

The Relationship Between Visuoconstructive Abilities and Language Performance in Patients With Aphasia After Stroke. 脑卒中后失语症患者视觉建构能力与语言表现的关系。

Brain & NeuroRehabilitation Pub Date : 2022-11-01 DOI: 10.12786/bn.2022.15.e28

Yu Mi Hwang, Hoyoung Yi, Jae-Ik Lee, Sung-Bom Pyun

{"title":"The Relationship Between Visuoconstructive Abilities and Language Performance in Patients With Aphasia After Stroke.","authors":"Yu Mi Hwang, Hoyoung Yi, Jae-Ik Lee, Sung-Bom Pyun","doi":"10.12786/bn.2022.15.e28","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e28","url":null,"abstract":"This study aimed to investigate the visuoconstructive abilities and the relationship between visuoconstructive function and language performance in aphasic patients. Right-handed 24 aphasic patients (males 14, females 10) with at least 3 months post-stroke and 32 age-matched healthy controls participated in this study. Visuoconstructive function was assessed by 3 levels of task difficulty: simple (drawing objects), intermediate (clock drawing), and complex (copy subtest of Rey complex figure test and block construction). Aphasic patients were divided into 3 sub-groups (mild, moderate to severe, and very severe group) according to severity of aphasia and compared with the control group, respectively. We analyzed the relation all levels of visuoconstructive tasks to aphasia quotient (AQ) and sub-domain scores of K-WAB. Moderate to severe aphasia group demonstrated no significant differences in scores of simple drawing objects compared to controls, but clock drawing, Rey complex figure copy and block design showed significantly decreased scores. Very severe group showed significantly lower scores in all levels of visuoconstructive tasks than the control. Correlation between all levels of visuoconstructive tasks except drawing objects and AQ were found to be statistically significant. Among the tasks, the clock drawing test revealed the highest correlation with language performance. Visuoconstructive abilities varied according to the severity of aphasia and the level of visuoconstructive tasks. Therefore, a thorough individual assessment of visuoconstructive function is needed to plan and predict the treatment and prognosis of aphasia and the clock drawing test may be a useful screening tool to evaluate this function.","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e28"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/a3/bn-15-e28.PMC9833482.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0