Seongsik Son, Kil-Byung Lim, Jeehyun Yoo, Pamela Song, Jiyong Kim
{"title":"Cognitive Impairment in a Child With Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report.","authors":"Seongsik Son, Kil-Byung Lim, Jeehyun Yoo, Pamela Song, Jiyong Kim","doi":"10.12786/bn.2023.16.e12","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e12","url":null,"abstract":"<p><p>Anti-N-methyl-D-aspartate-receptor encephalitis is a complex autoimmune inflammatory neurological disorder that presents with epileptic seizures and rapid functional deterioration, including movement disorders and cognitive impairment, especially in young patients. Despite aggressive initial treatment with immune therapy, such as corticosteroids, intravenous immunoglobulin, and plasmapheresis, patients often need intensive rehabilitative therapies for their long-lasting deficits. We report a pediatric case of anti-N-methyl-D-aspartate receptor encephalitis in Korea that presented with symptoms of muscle weakness of the four extremities, dysarthria, dysphagia, and cognitive impairment in the acute phase. The patient underwent 4 weeks of comprehensive rehabilitative treatment, including physical therapy, occupational therapy, swallowing rehabilitation therapy, cognitive rehabilitation therapy, and speech therapy. At the follow-up evaluation after 4 weeks of treatment, she showed significant improvements in limb muscle strength, balance ability, swallowing, language function, and the ability to perform activities of daily living. However, when assessed using the Korean Wechsler Intelligence Scale for Children-IV, there was little improvement in cognitive function, particularly in working memory. While only a few cases have reported the progression of cognitive function using a standardized cognitive evaluation tool in patients with anti-N-methyl-D-aspartate receptor encephalitis, this present case report adds to the accumulation of evidence of neurocognitive deficits in these patients.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 2","pages":"e12"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/71/bn-16-e12.PMC10404809.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9965185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seong-Yeol Kim, Choong-Hee Roh, Da-Sol Kim, Gi-Wook Kim, Yu Hui Won, Myoung-Hwan Ko, Jeong-Hwan Seo, Sung-Hee Park
{"title":"Ipsilateral Motor Evoked Potentials in a Preschool-age Child With Traumatic Brain Injury: A Case Report.","authors":"Seong-Yeol Kim, Choong-Hee Roh, Da-Sol Kim, Gi-Wook Kim, Yu Hui Won, Myoung-Hwan Ko, Jeong-Hwan Seo, Sung-Hee Park","doi":"10.12786/bn.2023.16.e20","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e20","url":null,"abstract":"<p><p>To the best of our knowledge, the upper age limit at which post-neonatal cerebral palsy (CP) can manifest remains uncertain. This uncertainty is attributed to the lack of objective parameters for assessing the developing brain. In a previous study, we reported that an ipsilateral corticospinal projection associated with brain injury, as manifested in the paretic hand of a CP patient, had never been observed in individuals aged > 2 years. In this case report, we present an instance of ipsilateral motor evoked potential (iMEP) in a girl whose traumatic brain injury occurred at the age of 4 years. This case is the oldest in which brain injury occurred and iMEP was maintained. In conclusion, iMEP can be a valuable indicator of motor system plasticity in the developing brain.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 2","pages":"e20"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cd/8f/bn-16-e20.PMC10404811.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9965181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brandon J Goodwin, Rahyan Mahmud, Saumya TomThundyil, Gerardo Rivera-Colon, Victoria Wong Murray, Kelly O'Donnell
{"title":"The Efficacy of Spinal Cord Stimulators in the Reduction of Multiple Sclerosis Spasticity: A Narrative Systematic Review.","authors":"Brandon J Goodwin, Rahyan Mahmud, Saumya TomThundyil, Gerardo Rivera-Colon, Victoria Wong Murray, Kelly O'Donnell","doi":"10.12786/bn.2023.16.e19","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e19","url":null,"abstract":"<p><p>A systematic review was employed utilizing Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, to analyze all primary clinical data on the efficacy of spinal cord stimulation (SCS) in the treatment of multiple sclerosis (MS) induced spasticity. Databases include: Embase, PubMed, Scopus, Cochrane, and Web of Science. The review included case series, case studies, and clinical trials. Outcomes of interest were spasticity reduction. Grading of Recommendations Assessment, Development and Evaluation criteria was utilized to grade the certainty of evidence. Five hundred thirty-two articles were retrieved following database systematic review. One hundred eighty-eight articles were removed as duplicates utilizing the \"Detect Duplicates\" function on Rayyan.ai. A further 344 articles were excluded following abstract and title appraisal. As a result, 16 articles were subjected to full text appraisal. The dates of publication ranged from 1973 to 2019. Although a unique modality, there is not enough evidence to support the employment of SCS over current medical standard of care. Further high-quality randomized control trials are required to elucidate SCS's role in MS induced spasticity algorithm.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 2","pages":"e19"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fd/98/bn-16-e19.PMC10404813.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9956240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Woosik Choi, So Jung Lee, Sung-Hwa Ko, Yong-Il Shin, Ji Hong Min
{"title":"Erratum: Peduncular Hallucinosis 7 Months After Pontine Hemorrhage With Hypertrophic Olivary Degeneration: A Case Report.","authors":"Woosik Choi, So Jung Lee, Sung-Hwa Ko, Yong-Il Shin, Ji Hong Min","doi":"10.12786/bn.2023.16.e2","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e2","url":null,"abstract":"<p><p>[This corrects the article e31 in vol. 15, PMID: 36742085.].</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e2"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/57/bn-16-e2.PMC10079475.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9265214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myeong Sun Kim, Ha Yeon Kim, Gyulee Park, Tae-Lim Kim, Joon-Ho Shin
{"title":"Cardiopulmonary Response to Robot-Assisted Tilt Table With Regard to Its Components.","authors":"Myeong Sun Kim, Ha Yeon Kim, Gyulee Park, Tae-Lim Kim, Joon-Ho Shin","doi":"10.12786/bn.2023.16.e9","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e9","url":null,"abstract":"<p><p>Cardiopulmonary function is exceptionally critical during the early stages of rehabilitation after neurological disorders such as stroke, spinal cord injury and Parkinson's disease. This study aimed to demonstrate how robot-assisted and tilt table exercises affect cardiopulmonary function. In this study, ten healthy young adults performed six combinations of conditions according to robot-assisted mode (on/off), angle of tilt table (20°/60°), and functional electrical stimulation (FES) mode (on/off). Four conditions had FES mode off with combinations of robot-assisted mode (on/off) and tilt angle (20°/60°) and two conditions had robot-assisted mode and FES on with tilt angle (20°/60°). Cardiopulmonary effects (oxygen uptake [VO<sub>2</sub>], peak oxygen uptake [VO<sub>2</sub>peak], metabolic energy cost [MET], rate pressure product [RPP], heart rate [HR], maximum heart rate [%HRmax], and minute ventilation [VE]) were compared in each condition. As a result, in the angle and FES mode effect, VO<sub>2</sub>, VO<sub>2</sub>peak, MET, RPP, HR, and %HRmax, unlike that for VE, showed major effects in angle. In addition, in the robot-assisted mode and angle effect, when the FES was switched off, VO<sub>2</sub>, METs, and VE values showed major effects in the robot-assisted mode, whereas all other values showed major effects in angle. Compared to earlier reported findings, we can expect that robot-assisted tilt table training can lead to changes in the cardiopulmonary function.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e9"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/29/bn-16-e9.PMC10079472.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9277925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to Letter to the Editor: Effects of Cognitive-Physical Dual-Task Training on Executive Function and Activity in the Prefrontal Cortex of Older Adults With Mild Cognitive Impairment.","authors":"Jin-Hyuck Park","doi":"10.12786/bn.2023.16.e6","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e6","url":null,"abstract":"Thajus Asirvatham raises important points. The first concern is about an outcome measurement used in the study to assess executive function. As he indicated, the Trail Making Test Part B (TMT-B) is one of conventional neuropsychological assessments, focusing on evaluating executive function itself rather than functionally assessing it. Nevertheless, the reason why the TMT-B was used is that one of the purposes of the study was to measure cerebral blood flow during executive functioning. The Korean version of the Executive Function Performance Test (EFPT-K) is a top-down performance assessment [3]. Since the EFPT-K requires participants to complete some tasks, measurements of cerebral blood flow using a functional near-infrared spectroscopy during the tasks might be inappropriate due to noise [4].","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e6"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/62/bn-16-e6.PMC10079473.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9277926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seung-Min Baek, Seung-Bok Lee, Eun-Ae Yoo, Yeong-Il Na, Kwang-Jae Lee
{"title":"Isolated Oculomotor Nerve Palsy After Temporoparietal Lobar Hemorrhage With a Mass Effect: A Case Report.","authors":"Seung-Min Baek, Seung-Bok Lee, Eun-Ae Yoo, Yeong-Il Na, Kwang-Jae Lee","doi":"10.12786/bn.2023.16.e1","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e1","url":null,"abstract":"<p><p>We report a case of a patient who presented with ipsilateral oculomotor nerve palsy after a spontaneous left temporoparietal lobar hemorrhage with mass effect. Primary symptomatology included ipsilateral ptosis, dilated fixed pupil, and a lack of superior and medial movement with limited inferior left eye movements. Brain imaging revealed compression of the left upper midbrain due to subtentorial herniation of the hemorrhage, and susceptibility-weighted images sequences showed cerebral microbleed in the left midbrain substantia nigra. Based on our observation from this case, physicians should consider temporoparietal lobar hemorrhage with mass effect as an attributable factor in the etiologic cause of ipsilateral oculomotor nerve palsy.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/7b/bn-16-e1.PMC10079481.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9272427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soo Hoon Yoon, Jae Ik Lee, Mun Jeong Kang, Hae In Lee, Sung-Bom Pyun
{"title":"Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study.","authors":"Soo Hoon Yoon, Jae Ik Lee, Mun Jeong Kang, Hae In Lee, Sung-Bom Pyun","doi":"10.12786/bn.2023.16.e3","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e3","url":null,"abstract":"<p><p>Gerstmann syndrome (GS) is a rare syndrome that occurs when there is a lesion of the dominant inferior parietal lobule (IPL), causing agraphia, acalculia, finger agnosia, and right-left disorientation. A 49-year-old right-handed male was diagnosed as GS after left parieto-occipital lobe hemorrhage. The patient showed mild anomic aphasia with agraphia in the language test and the neuropsychological test revealed acalculia, impaired right-left discrimination, and finger agnosia. In diffusion tensor tractography, the tracts of left superior longitudinal fasciculus (SLF), middle longitudinal fasciculus, U-fibers and posterior corpus callosum (CC) were disrupted around the left IPL. In addition, fractional anisotropy (FA) values were markedly decreased in left SLF, and posterior CC when compared to twelve healthy control subjects. Our clinical and neuroimaging findings support that GS is a disconnection syndrome caused by lesion in the white matter pathway surrounding IPL. In future, more studies of the correlation between the white matter disconnection and the development of GS including high quality imaging technique are needed.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e3"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/e4/bn-16-e3.PMC10079479.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9277924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hee-Mun Cho, Hyunji Kim, Jihee Jang, Seungwoo Cha, Won Kee Chang, Bong-Keun Jung, Dae-Sung Park, Sungju Jee, Sung-Hwa Ko, Joon-Ho Shin, Won-Seok Kim, Nam-Jong Paik
{"title":"Attitude Toward Telerehabilitation Among Physical and Occupational Therapists in Korea: A Brief Descriptive Report.","authors":"Hee-Mun Cho, Hyunji Kim, Jihee Jang, Seungwoo Cha, Won Kee Chang, Bong-Keun Jung, Dae-Sung Park, Sungju Jee, Sung-Hwa Ko, Joon-Ho Shin, Won-Seok Kim, Nam-Jong Paik","doi":"10.12786/bn.2023.16.e8","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e8","url":null,"abstract":"<p><p>The attitude toward telerehabilitation (TR) among therapists (191 physical therapists and 159 occupational therapists) in Korea was surveyed. The survey consisted of 15 questions in the following 8 domains: awareness(AW), attitude (AT), perceived usefulness (PU), perceived behavioral control (PBC), self-efficacy (SE), facilitating conditions (FC), barriers (B), and behavioral intention (BI). Therapists with experience in TR responded with higher scores in all domains except B, regardless of their specialty. The most perceived barriers to TR were unmatched insurance fees and a lack of technical support. Experience with TR was a major factor in attitude and behavior intention toward TR.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e8"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/66/89/bn-16-e8.PMC10079478.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9272570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyemi Hwang, Soohoan Lee, Hae-Yeon Park, Hee Young Lim, Kyung Hyun Park, Geun-Young Park, Sun Im
{"title":"Investigating the Impact of Voice Impairment on Quality of Life in Stroke Patients: The Voice Handicap Index (VHI) Questionnaire Study.","authors":"Hyemi Hwang, Soohoan Lee, Hae-Yeon Park, Hee Young Lim, Kyung Hyun Park, Geun-Young Park, Sun Im","doi":"10.12786/bn.2023.16.e10","DOIUrl":"https://doi.org/10.12786/bn.2023.16.e10","url":null,"abstract":"<p><p>The Voice Handicap Index (VHI) is a patient-centered evaluation tool specifically designed for assessing voice-related quality of life. Although the VHI has been extensively used in patients with voice disorders, its applicability in stroke patients has not been fully established. This prospective cross-sectional study aimed to investigate the feasibility of using the VHI questionnaire in identifying stroke patients with voice problems. The study included a cohort of acute to subacute first-ever stroke patients (n = 48), with or without voice problems, as well as other non-stroke patients (n = 31) who agreed to complete the VHI questionnaire. Stroke patients with self-reported voice problems demonstrated significantly higher VHI scores and poorer life quality scores compared to the control groups. These patients also had lower Mini-Mental State Examination (MMSE), Modified Barthel Index (MBI), and Euro-QoL-5D-5L (EQ-5D-5L) scores. Spearman correlation analysis revealed an inverse association between VHI scores and EQ-5D-5L (rho = -0.77, p < 0.001), Korean Mann Assessment of Swallowing Ability (rho = -0.51, p < 0.001), and other functional parameters, including the National Institutes of Health Stroke Scale, MMSE, and MBI scores. Multiple regression analysis indicated that the VHI score was the biggest contributing factor to EQ scores. This is the first study to demonstrate that stroke patients with voice problems may experience reduced quality of life, even after controlling for other confounding factors such as dysphagia or neurological deficits. Future studies are needed whether addressing these issues by implementing the VHI may facilitate the improvement of patients' quality of life.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"16 1","pages":"e10"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b6/72/bn-16-e10.PMC10079476.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9272571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}