{"title":"Treatment of Adult Gliomas: A Current Update.","authors":"Joo Ho Lee, Chan Woo Wee","doi":"10.12786/bn.2022.15.e24","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e24","url":null,"abstract":"<p><p>Gliomas are the most common type of primary brain tumor in adults. Glioma treatment requires a multidisciplinary approach involving surgery, radiotherapy, and chemotherapy. Multiple trials have been conducted to establish the appropriate choice of treatment to achieve long-term survival and better quality of life. This review provides up-to-date evidence regarding treatment strategies for gliomas.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e24"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/11/bn-15-e24.PMC9833488.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu Mi Hwang, Hoyoung Yi, Jae-Ik Lee, Sung-Bom Pyun
{"title":"The Relationship Between Visuoconstructive Abilities and Language Performance in Patients With Aphasia After Stroke.","authors":"Yu Mi Hwang, Hoyoung Yi, Jae-Ik Lee, Sung-Bom Pyun","doi":"10.12786/bn.2022.15.e28","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e28","url":null,"abstract":"<p><p>This study aimed to investigate the visuoconstructive abilities and the relationship between visuoconstructive function and language performance in aphasic patients. Right-handed 24 aphasic patients (males 14, females 10) with at least 3 months post-stroke and 32 age-matched healthy controls participated in this study. Visuoconstructive function was assessed by 3 levels of task difficulty: simple (drawing objects), intermediate (clock drawing), and complex (copy subtest of Rey complex figure test and block construction). Aphasic patients were divided into 3 sub-groups (mild, moderate to severe, and very severe group) according to severity of aphasia and compared with the control group, respectively. We analyzed the relation all levels of visuoconstructive tasks to aphasia quotient (AQ) and sub-domain scores of K-WAB. Moderate to severe aphasia group demonstrated no significant differences in scores of simple drawing objects compared to controls, but clock drawing, Rey complex figure copy and block design showed significantly decreased scores. Very severe group showed significantly lower scores in all levels of visuoconstructive tasks than the control. Correlation between all levels of visuoconstructive tasks except drawing objects and AQ were found to be statistically significant. Among the tasks, the clock drawing test revealed the highest correlation with language performance. Visuoconstructive abilities varied according to the severity of aphasia and the level of visuoconstructive tasks. Therefore, a thorough individual assessment of visuoconstructive function is needed to plan and predict the treatment and prognosis of aphasia and the clock drawing test may be a useful screening tool to evaluate this function.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e28"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/a3/bn-15-e28.PMC9833482.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brain Tumor Rehabilitation: Symptoms, Complications, and Treatment Strategy.","authors":"Jinyoung Park, Yoon Ghil Park","doi":"10.12786/bn.2022.15.e25","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e25","url":null,"abstract":"<p><p>Brain tumors are receiving increasing attention in cancer rehabilitation due to their high rate of neurological deterioration. Motor dysfunction, cognitive deterioration, and emotional problems are commonly present in patients with brain tumors. Other medical complications, such as seizures, headache, and dysphagia are also common. An individualized multidisciplinary rehabilitation intervention is necessary to treat functional impairment due to the tumor itself and/or treatment-related dysfunction. Herein, we discuss rehabilitation treatment strategies in relation to the neurological and functional complications that commonly occur in patients with brain tumors.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e25"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/88/bn-15-e25.PMC9833490.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9229769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Machine Learning in Stroke Rehabilitation: A Narrative Review.","authors":"Yoo Jin Choo, Min Cheol Chang","doi":"10.12786/bn.2022.15.e26","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e26","url":null,"abstract":"<p><p>A narrative review was conducted of machine learning applications and research in the field of stroke rehabilitation. The machine learning models commonly used in medical research include random forest, logistic regression, and deep neural networks. Convolutional neural networks (CNNs), a type of deep neural network, are typically used for image analysis. Machine learning has been used in stroke rehabilitation to predict recovery of motor function using a large amount of clinical data as input. Recent studies on predicting motor function have trained CNN models using magnetic resonance images as input data together with clinical data to increase the accuracy of motor function prediction models. Additionally, a model interpreting videofluoroscopic swallowing studies was developed and investigated. In the future, we anticipate that machine learning will be actively used to treat stroke patients, such as predicting the occurrence of depression and the recovery of language, cognitive, and sensory function, as well as prescribing appropriate rehabilitation treatments.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e26"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/81/bn-15-e26.PMC9833483.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9214094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Han Su Kim, Hyun Woo Cho, Yeon Jun Kim, Soo Jin Jung
{"title":"Progressive Multifocal Leukoencephalopathy With Hyper-IgM Syndrome in a 6-Year-Old Boy.","authors":"Han Su Kim, Hyun Woo Cho, Yeon Jun Kim, Soo Jin Jung","doi":"10.12786/bn.2022.15.e32","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e32","url":null,"abstract":"<p><p>Hyper-immunoglobulin (Ig) M syndrome is a congenital immunodeficiency disorder characterized by increased serum IgM with low serum IgG, IgA, and IgE. We report the case of a 6-year-old boy with hyper-IgM syndrome as an underlying disease who showed progressive multifocal leukoencephalopathy findings on brain magnetic resonance imaging after visiting the hospital due to left upper extremity muscle weakness, gait disturbance, and speech impairment. At the time of hospitalization, he was treated with steroids and intravenous immunoglobulin, and his condition improved somewhat, but 6 months later, he visited the hospital with rapid deterioration.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e32"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/f1/bn-15-e32.PMC9833491.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9229762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative Measurement of Dysphonia Severity in Patients With Stroke With Unilateral Vocal Cord Palsy.","authors":"Min Kyu Choi, Eo Jin Park, Seung Don Yoo","doi":"10.12786/bn.2022.15.e29","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e29","url":null,"abstract":"<p><p>Unilateral vocal cord palsy (UVCP) is frequently observed in patients with stroke. This study aimed to evaluate the association between objective dysphonia severity and the classification of UVCP in patients with stroke by objectively and quantitatively measuring their phonetic function. We recruited patients with UVCP diagnosed using laryngoscopy after stroke. Subgroups were divided according to UVCP type, and the dysphonia severity index (DSI) and maximum phonation time (MPT) were measured to objectively evaluate dysphonia. The DSI and MPT were compared between subgroups using analysis of variance with Tukey's honest significant difference post hoc test. In total, 103 patients with stroke and UVCP were recruited. We found that a higher UVCP severity possibly had to do with lower DSI and MPT values. We objectively confirmed that phonetic function was worse in patients with stroke with higher UVCP severity, and the DSI and MPT tests can be helpful in determining the severity and need for additional evaluation.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 3","pages":"e29"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/89/bn-15-e29.PMC9833489.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9229766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment and Rehabilitation for Traumatic Brain Injury: Current Update.","authors":"Ji Hong Min, Yong-Il Shin","doi":"10.12786/bn.2022.15.e14","DOIUrl":"10.12786/bn.2022.15.e14","url":null,"abstract":"<p><p>Traumatic brain injury (TBI) is an acquired injury to the brain caused by external mechanical forces, which can cause temporary or permanent disability. TBI and its potential long-term consequences are serious public health concerns. This review seeks to provide updated information on the current methods of management of patients with TBI to improve patient care.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 2","pages":"e14"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/b7/bn-15-e14.PMC9833473.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Update on Stroke Rehabilitation in Motor Impairment.","authors":"Yeong Wook Kim","doi":"10.12786/bn.2022.15.e12","DOIUrl":"10.12786/bn.2022.15.e12","url":null,"abstract":"<p><p>Motor impairment due to stroke limits patients' mobility, activities of daily living, and negatively affects their return to the workplace. It also reduces patients' quality of life and increases the socioeconomic burden of stroke. Therefore, optimizing the recovery of motor impairment after stroke is a very important goal for both individuals and society as a whole. The emergence and improvement of various technologies in the Fourth Industrial Revolution have exerted a major influence on the development of new rehabilitation methods and efficiency enhancements for existing methods. This review categorizes rehabilitation methods that promote the recovery of motor function into upper limb function and lower limb function and summarizes recent advances in stroke rehabilitation. Although debate continues regarding the effects of some rehabilitation therapies, it is hoped that the evidence will be improved through ongoing research so that clinicians can treat patients with a higher level of evidence.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 2","pages":"e12"},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/4a/bn-15-e12.PMC9833472.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Lower Limb Motor Function, Ambulation, and Balance After Stroke.","authors":"Yeun Jie Yoo, Seong Hoon Lim","doi":"10.12786/bn.2022.15.e17","DOIUrl":"10.12786/bn.2022.15.e17","url":null,"abstract":"<p><p>Restoration of ambulation is important for stroke patients. Valid and reliable methods are required for the assessment of lower limb functional status. We reviewed the psychometric properties of methods employed to assess lower extremity motor function, ambulation, and balance, with a focus on stroke patients. We define \"motor function\" as the ability to produce bodily movements when the brain, motor neurons, and muscles interact. \"Ambulation\" is defined as the ability to walk with or without a personal assistive device, and \"balance\" as the ability to maintain stability (without falling) during various physical activities. The Motricity Index and Fugl-Meyer Assessment of Lower Extremities assess the motor function of the lower limbs. The Functional Ambulation Category, 10-m Walk Test, and 6-minute Walk Test assess ambulation. The Berg Balance Scale, Timed Up and Go Test, Functional Reach Test, and Trunk Impairment Scale explore balance. All these tests exhibit high-level validity and have good inter-rater and test-retest reliabilities. However, only 3 methods have been formally translated into Korean. The methods discussed here can be used for standardized assessment, personalized goal setting, rehabilitation planning, and estimation of therapeutic efficacy.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 2","pages":"e17"},"PeriodicalIF":0.0,"publicationDate":"2022-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/3a/bn-15-e17.PMC9833471.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10663202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yang Rok Hur, Woo Sup Song, Kyung Min Kim, Ki Hun Hwang
{"title":"Comparison Between Comprehensive Nursing Care Ward and Private Care Ward on Functional Recovery in Stroke Patients.","authors":"Yang Rok Hur, Woo Sup Song, Kyung Min Kim, Ki Hun Hwang","doi":"10.12786/bn.2022.15.e21","DOIUrl":"https://doi.org/10.12786/bn.2022.15.e21","url":null,"abstract":"<p><p>The need for a comprehensive nursing care service ward (CNCW) is emerging, but few studies have investigated its medical validity. This study aimed to assess the effect of hospitalization on functional recovery and fall incidence in poststroke patients. This retrospective study enrolled 354 patients with subacute stroke between July 2017 and April 2020. CNCW provided full caregiving and nursing to the patient. Baseline demographic and hospital data, including fall occurrence, were collected. Functional outcomes, including the Medical Research Council (MRC), Korean version of the Modified Barthel Index (K-MBI), and Korean version of the Mini-Mental State Examination (K-MMSE), were evaluated upon admission and discharge. One hundred seventy-two patients were hospitalized in CNCW among the 354 stroke patients. Initial and final K-MMSE and K-MBI were significantly higher in the CNCW group. The K-MMSE score gain was significantly lower in the CNCW group (p < 0.05). The fall occurrence was significantly higher in the CNCW group (p < 0.01). Hospitalization in CNCW adversely affected cognitive function after stroke. Falls were detected more frequently and reported in CNCW.</p>","PeriodicalId":72442,"journal":{"name":"Brain & NeuroRehabilitation","volume":"15 2","pages":"e21"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/16/bn-15-e21.PMC9833468.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10663203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}