BMC primary care最新文献

{"title":"Time is health: management of Parkinson's disease in primary care: a retrospective quantitative study of diagnostic and therapeutic timelines.","authors":"Sabine Bayen, Xavier Lagon, Charles Cauet, Marc Bayen, Teddy Richebe, Nassir Messaadi, Matthieu Calafiore","doi":"10.1186/s12875-025-02911-0","DOIUrl":"10.1186/s12875-025-02911-0","url":null,"abstract":"","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"217"},"PeriodicalIF":2.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12226921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A proposed algorithm for early autism screening in Polish primary care settings - a pilot study.","authors":"Patryk Domarecki, Katarzyna Plata-Nazar, Wojciech Nazar","doi":"10.1186/s12875-025-02914-x","DOIUrl":"10.1186/s12875-025-02914-x","url":null,"abstract":"<p><strong>Background: </strong>The rising rate of autism spectrum disorder (ASD) prevalence worldwide demands new screening algorithms to make the process of diagnosis more effective. General practitioners and pediatricians are well-positioned to screen all children aged 16 to 30 months during regular check-ups. In the research, the original algorithm for early autism screening in Polish primary care settings was proposed and tested.</p><p><strong>Methods: </strong>Based on the literature review, the original algorithm of early autism screening employing observational tool was developed and tested. Personal data and M-CHAT-R/F were collected online. In the second phase, chosen patients participated in the Screening Tool for Autism in Toddlers and Young Children (STAT). Children who scored positive were referred for the comprehensive ASD evaluation. Normal distribution was analyzed with the use of the Shapiro-Wilk test. Chosen variables were compared using the U-Mann Whitney (nonparametric data) or Student's t-test (parametric data). The Spearman's rank correlation coefficient was calculated to analyze the strength of association between selected continuous variables. The threshold of the two-sided statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>Of 187 parents invited to the project, 159 filled the form in the first phase. According to the protocol, 29 children were chosen for the second stage. 10 children scored positive in the STAT session and were referred for comprehensive evaluation. 5 children out of the seven who attended the evaluation received a final diagnosis of ASD. Parental concerns were found the strongest predictor of M-CHAT-R/F results. Fear of having a child with ASD diagnosis was the most common reason for withdrawal from further steps of the protocol.</p><p><strong>Conclusions: </strong>The proposed algorithm for early developmental screening in the Polish primary care settings is a promising pathway with the potential to be implemented in clinical practice. It contributes to the early detection of developmental difficulties and therefore results in positive therapeutic outcomes. Further research is needed.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"216"},"PeriodicalIF":2.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STEPWISE management of clinically apparent resistant hypertension in primary care: a cluster randomised controlled trial.","authors":"Birsen Kiliç, Marion C J Biermans, Michiel L Bots, Mark van der Wel, Wim J C de Grauw, Frans H Rutten, Monika Hollander","doi":"10.1186/s12875-025-02885-z","DOIUrl":"10.1186/s12875-025-02885-z","url":null,"abstract":"<p><strong>Background: </strong>Clinically apparent resistant hypertension (CARH) is common and a major health problem because it increases the risk of cardiovascular events. We aim to assess whether a stepwise work-up management strategy for patients with CARH in primary care would result in better blood pressure control compared to usual care.</p><p><strong>Methods: </strong>A pragmatic, cluster-randomised controlled trial (cRCT). General practitioners (GPs) from 22 practices (10 intervention arm; 12 usual care) recruited 106 patients aged 18-80 years who had an office blood pressure (BP) > 140/90 mmHg and were prescribed three or more antihypertensive drugs from different therapeutic classes for three or more months in an adequate dose. This study was conducted between October 2018 and June 2021. The intervention was a stepwise approach comprising of (i) 24-hour blood pressure measurements, (ii) dedicated attention on intake of blood pressure raising compounds, (iii) on lifestyle and on compliance to and (iv) optimalisation of medication, and (v) referral to specialist care, when appropriate. The control group received usual care. Primary outcome was the difference in 24-hours systolic BP between intervention and usual care measured at 8 months after baseline.</p><p><strong>Results: </strong>Neither 24-hour nor office systolic BP 8 months after baseline significantly differed between intervention and usual care arm: 136.9 mmHg versus 132.6 mmHg (p = 0.15) and 146.1 mmHg versus 147.6 mmHg (p = 0.51), respectively. No significant differences across groups were seen in number of prescribed BP lowering medication: 2.98 versus 3.11, or controlled hypertension after 8 months: 22% versus 28%.</p><p><strong>Conclusions: </strong>Our results suggest that a pragmatic, structured stepwise approach of CARH does not result in lower 24 h or office BP values compared to usual primary care.</p><p><strong>Trial registration: </strong>NTR7304 (www.trialregister.nl/trial/7099), May 4th, 2018.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"212"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12218076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of the physical activity counseling practices scale in health professionals: a validity and reliability study.","authors":"Musa Çankaya, Serdar Arslan, Gökmen Yapalı","doi":"10.1186/s12875-025-02909-8","DOIUrl":"10.1186/s12875-025-02909-8","url":null,"abstract":"<p><strong>Objective: </strong>The aim is to develop the scale of Physical Activity Counseling Practices (PACPS) in Turkish and validate it among health professionals.</p><p><strong>Methods: </strong>PACPS test-retest was applied to 162 health professionals (physician, physiotherapist, dietician, nurse) with a 1-week interval. Construct validity, correlations of PACPS with other scales were evaluated with the International Physical Activity Questionnaire short form (IPAQ), Conscious Behavioral Physical Activity Questionnaire (CBAPQ).</p><p><strong>Results: </strong>The content validity index value of the scale was found to be 0.76. The overall internal consistency of the scale (Cronbach α:0.917) was high. The item-total correlations of the scale are between 0.45 and 0.76.</p><p><strong>Conclusion: </strong>This study, it was determined that the PACPS scale has good internal consistency, test-retest validity and sufficient construct validity when compared with the IPAQ and CBAPQ.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"209"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12219883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of digital platform in reducing unintentional medication discrepancies at transition of care from hospital discharge to primary healthcare settings: a randomised controlled trial.","authors":"Yen Yen Phang, Jew Win Kuan, Ai Ling Oh, Chuo Yew Ting, Nor Anizah Osman, Stephen Moses","doi":"10.1186/s12875-025-02904-z","DOIUrl":"10.1186/s12875-025-02904-z","url":null,"abstract":"<p><strong>Background: </strong>Modifications to medication regimens during transitions of care between different healthcare settings often lead to unintentional medication discrepancies (UMDs). The MedBook Portal, a simple digital platform that enables the sharing of patient medication records among healthcare facilities under Ministry of Health, was developed to facilitate medication reconciliation at primary health clinic (PHC) after hospital discharge. This study aimed to determine the effectiveness of MedBook Portal in reducing UMDs in the first prescription during the first PHC visit after hospital discharge.</p><p><strong>Methods: </strong>This two-arm, parallel, non-blinded, randomised controlled trial was conducted at four public hospitals and ten public PHCs in Sarawak, Malaysia, from May 2023 to July 2024. Adult patients aged ≥ 18 years in general medical wards, discharged from hospitals, and referred to selected PHCs were recruited. In the Standard Care group, PHC doctors performed standard medication reconciliation by reviewing patients' medical records on their home-based medical cards and discharge notes, if available. In the MedBook Portal group, in addition to this process, PHC doctors logged into MedBook Portal to access the discharge prescription before issuing a new prescription.</p><p><strong>Results: </strong>Among the 339 eligible subjects randomised into MedBook Portal group and Standard Care group, 307 participants (147 MedBook Portal, 160 Standard Care) were analysed after excluding those for whom the intervention was not performed (n = 11) and those with no prescription (n = 21). The incidence rate of prescription with UMDs was significantly lower in the MedBook Portal group (5/147, 3.4%) compared to the Standard Care group (30/160, 18.8%) (p < 0.001). The most common UMD was drug omission (54.4%). Multivariable logistic regression showed that the presence of MedBook Portal reduced the odds of UMDs by 87% (adjusted OR 0.134, 95% CI 0.049-0.336, p < 0.001), whereas each additional comorbidity increased the odds by 52% (adjusted OR 1.520, 95% CI 1.158-2.020, p = 0.003).</p><p><strong>Conclusions: </strong>Medication reconciliation using the MedBook Portal effectively reduces UMDs during the transition of care from hospital discharge to PHCs, enhancing patient safety across the continuum of care.</p><p><strong>Trial registration: </strong>ClinicalTrials.Gov (NCT06517160) was registered retrospectively on 19 September 2024.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"206"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12219133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-designing a shared digital decision aid for HPV vaccination in French general practice.","authors":"Dragos-Paul Hagiu, Arthur Tron, Minghui Zuo, Marie Ecollan, Juliette Pinot, Henri Partouche, Serge Gilberg, Josselin Le Bel, Louise Rossignol, Aurélie Gauchet, Amandine Gagneux-Brunon, Morgane Michel, Judith E Mueller, Nathalie Thilly, Sébastien Bruel","doi":"10.1186/s12875-025-02910-1","DOIUrl":"10.1186/s12875-025-02910-1","url":null,"abstract":"<p><strong>Background: </strong>Human papillomavirus (HPV) is responsible for the most common sexually transmitted infection in the world and persistent infection of oncogenic types is associated with an increased risk of cancers. This infection could be prevented by vaccination. However, in a time of vaccine hesitancy, the decision to get vaccinated or to have a child vaccinated is the result of a complex process and decision aids are tools that may be of help in this context.</p><p><strong>Objective: </strong>The aim of this article is to present the development of a shared decision aid for HPV vaccination in France, destined to be used during general practice consultations.</p><p><strong>Methods: </strong>In order to develop the shared decision aid, we followed the steps recommended by the International Patient Decision Aids Standard (IPDAS), i.e. scoping and defining the objectives, assembling the steering group, designing (carrying out two focus groups and a narrative review of the literature) and testing in a alpha test phase (carrying out three focus groups and 11 individual interviews). The tool was co-constructed with adolescents, parents and general practitioners.</p><p><strong>Results: </strong>We created an online shared decision aid which included the definition of HPV, epidemiological data, the mode of contamination, the different locations of the disease, the development of cancer, the importance of Pap smears, the effectiveness of the vaccination as well as the possible side effects. The various focus groups as well as individual interviews made it possible to determine the values and expectations of patients and physicians thus improving the decision aid. This development also made it possible to confirm an existing need for this type of tool for both patients and physicians.</p><p><strong>Conclusions: </strong>We have developed a shared decision aid that could help general practitioners communicate about HPV vaccination and get more patients vaccinated. The impact of its use during the consultation will be evaluated on criteria such as the resolution of the decision-making conflict and ultimately on the vaccination coverage, as part of the PrevHPV study.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"215"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12225063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General practitioners' management of occupational diseases: a qualitative study in French-speaking Switzerland.","authors":"Gaubicher Coline, Staeger Philippe, Danuser Brigitta, Abderhalden-Zellweger Alessia, Krief Peggy, Mediouni Zakia","doi":"10.1186/s12875-025-02888-w","DOIUrl":"10.1186/s12875-025-02888-w","url":null,"abstract":"<p><strong>Background: </strong>Work-related health problems are a frequent reason for consultation with primary care physicians; however, few studies report on the way general practitioners' (GPs) approach work-related health issues with their patients.</p><p><strong>Aim: </strong>To investigate the practices of Swiss GPs in regarding work-related health issues presented by their patients, and to identify the resources and difficulties they faced.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 12 GPs, transcribed, and analyzed thematically.</p><p><strong>Results: </strong>GPs do explore their patients' occupational field. However, the data collected are limited, even though doctors recognize that a high proportion of mental and musculoskeletal disorders may be work-related. Work-related disease insurance issues are a frequent concern in GPs everyday practice, often causing a discomfort regarding these issues. Exchanges between GPs and employers regarding work-related health issues are relatively uncommon but can yield positive outcomes when they occur. Occupational risk prevention is confined to certain high-risk exposures. When asked to express their difficulties in dealing with work-related issues, GPs mention the lack of dedicated time, insurance issues, contact with employers or the lack of it and lack of training. As for resources, GPs mainly identify specialist doctors, but still, only few of them mention occupational physicians.</p><p><strong>Conclusions: </strong>Some work-related pathologies, whether frequent or serious, are not systematically investigated by GPs. This raises the question of their detection and probable under-reporting. To improve anamnesis, identification, and referral practices for occupational health issues, we suggest a targeted training for GPs, strengthened networking among stakeholders-such as occupational physicians, employers and insurers- and a revision of medical billing structures to better support the management of work-related diseases for both GPs and occupational physicians.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"207"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12220256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitators and barriers to deferring imaging for acute low back pain: a qualitative study.","authors":"Carly A Robinson, Melissa M Gosdin, Camille S Cipri, Ilona Fridman, Gary Weinberg, Anthony Jerant, Andrew Hudnut, Joshua J Fenton","doi":"10.1186/s12875-025-02902-1","DOIUrl":"10.1186/s12875-025-02902-1","url":null,"abstract":"<p><strong>Background: </strong>Early imaging for uncomplicated acute low back pain has no diagnostic benefit yet is completed after nearly one-quarter of primary care visits for acute back pain. This qualitative study examined patient and clinician perspectives on facilitators and barriers to deferring imaging for acute low back pain, including potential messages regarding a watchful waiting strategy without early imaging.</p><p><strong>Methods: </strong>Qualitative data derived from six patient focus groups (N = 30 patients with recent visits for acute low back pain) in Sacramento, CA and nine semi-structured physician interviews in 2020. Patients were asked about expectations regarding imaging, perceptions of care received for acute low back pain, and perspectives about potential messages encouraging a watchful waiting approach without early imaging. Clinicians were asked about facilitators and barriers to deferring low-value imaging. We used thematic analysis guided by grounded theory to identify and integrate themes.</p><p><strong>Results: </strong>Over half of patients had received early imaging during their recent back pain episode. Patients expected physicians to provide a detailed rationale for ordering imaging or not. Patients were typically not persuaded by information on potential harms of imaging and sometimes thought discussion of imaging harms would undermine their trust in the clinician. Patients would be more willing to defer imaging if provided detailed and empathic guidance on pain management. Physicians expressed confidence in advocating a watchful waiting approach without imaging but acknowledged challenges in building patient trust during time-pressed visits, particularly when seeing patients for the first time.</p><p><strong>Conclusions: </strong>This qualitative study highlights several challenges to deferring early imaging in acute low back pain, as patients typically expect early imaging and were skeptical of clinician messaging about imaging harms. Physicians highlighted lack of a previously established, trustful relationship as a common structural barrier to deferring low-value spinal imaging.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"204"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12220053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural adaptation of the pharmacy services questionnaire (PSQ) to the context of Angola.","authors":"Bernardo Nicodemo Chimbuco, João Rui Pita, Edson Zangiacomi Martinez, Claudia Benedita Dos Santos, Eduardo Ekundi-Valentim","doi":"10.1186/s12875-025-02912-z","DOIUrl":"10.1186/s12875-025-02912-z","url":null,"abstract":"<p><strong>Introduction: </strong>Community pharmacies have been essential in primary health care globally, especially in common health conditions. During the Covid-19 pandemic, it played an important role in rapid testing, managing patients with symptoms, and providing essential medications. This study aims to carry out a cross-cultural adaptation of the Pharmacy Services Questionnaire to obtain a version adapted for use in Angola, ensuring semantic, item, conceptual and operational equivalences between the two versions.</p><p><strong>Method: </strong>The study followed guidelines established in the literature for the cross-cultural adaptation of the instrument. This is a methodological study with a pretesting phase, carried out with a total of 40 participants, being 10 in the adaptation phase and 30 in the pretesting phase. Ten pharmacies were selected by convenience in three cities, Malanje, Cuanza Norte and Luanda in Angola, where data were collected with users selected according to education levels. The process of cultural adaptation was carried out in four stages: 1^st. Translation of Pharmacy Services Questionnaire items, 2^nd. Back-translation of the items, 3^rd Comparison of the original versions, translated and back-translated by a committee of judges and 4^th. Pretesting.</p><p><strong>Results: </strong>In phases 1, 2 and 3, 10 professionals with higher education were included and in phase 4, 30 users selected according to complete levels of education, 6 with higher education, 6 with high school, 6 with secondary education, 6 with primary education and 6 illiterates. Based on the analysis of responses from the DISABKIDS General Sheet, the feedback from participants suggests a high level of satisfaction with the questionnaire. The majority found it clear and easy to understand, and most considered the questions relevant and important. These findings indicate that the Angolan version of the questionnaire (PSQ-A) has been well-received and appears to be suitable for continued use in this context.</p><p><strong>Conclusions: </strong>The Angolan version of the Pharmacy Services Questionnaire was called the Questionnaire on Pharmacy Services (PSQ-A) and showed conceptual, item, semantic and operational equivalence. To ensure the equivalence of PSQ-A measures, a study on psychometric properties will be addressed in the future when policymakers and service providers have information on the performance of pharmaceutical services from the patient's perspective.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"213"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12219692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating a 52-week fresh food prescribing program in Ontario, Canada: A mixed-methods study on food insecurity, fruit and vegetable intake, and health.","authors":"Laura Jane Brubacher, Matthew Little, Ashmita Grewal, Eleah Stringer, Abby Richter, Warren Dodd","doi":"10.1186/s12875-025-02907-w","DOIUrl":"10.1186/s12875-025-02907-w","url":null,"abstract":"<p><strong>Background: </strong>Food insecurity is linked with suboptimal diet and comprises an important risk factor for nutrition-related chronic diseases. Fresh food prescription programs are designed to improve access to healthy foods, but there is limited evidence on the impacts of such programs in the Canadian context. The objective of this mixed methods study was to assess changes in food security, fruit and vegetable intake, and health among adult participants of a fresh food prescribing program in Guelph, Ontario, Canada.</p><p><strong>Methods: </strong>A total of 57 adult participants who were experiencing food insecurity and had ≥ 1 cardio-metabolic condition or micronutrient deficiency received fresh food prescriptions from their healthcare practitioner, which included a nutrition and cooking information package and weekly vouchers ($10 per person in household) for an online produce market for 52 consecutive weeks. Pre-, mid-, and post-intervention surveys, blood pressure measurements, and clinical bloodwork were collected to assess food security, fruit and vegetable intake, self-reported health, and blood biomarkers of cardio-metabolic and nutritional health. We used a single-arm repeated-measures evaluation and paired t-tests and Fisher's exact tests to assess changes. Linear regression models were used to assess factors associated with change in fruit and vegetable intake. Semi-structured interviews were conducted with participants to expand on survey findings. Qualitative data were analyzed thematically using an inductive constant comparative approach.</p><p><strong>Results: </strong>Forty-nine participants completed post-intervention data collection. The proportion of participants experiencing severe food insecurity decreased after the intervention from 38.1% to 23.8%. Intake of fruit, orange vegetables, and 'other' vegetables increased during the intervention (p < 0.05). Mean triglyceride, fasting insulin, and ascorbic acid levels improved (p < 0.05). More severe food insecurity and lower fruit and vegetable intake at baseline, as well as more frequent interaction with healthcare providers, were associated with a greater increase in fruit and vegetable intake from pre- to post-intervention (p < 0.05). In interviews, participants reported that the program increased access to fresh fruits and vegetables, improved mental and physical health, provided social connections, and reduced financial stress.</p><p><strong>Conclusions: </strong>Fresh food prescription programs may improve food security and increase fruit and vegetable intake, but further research is needed to determine their long-term health impacts.</p>","PeriodicalId":72428,"journal":{"name":"BMC primary care","volume":"26 1","pages":"208"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12219258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}