Biomaterial investigations in dentistry最新文献

{"title":"Incorporation of selenium nanoparticles into mineral trioxide aggregate used as a direct pulp capping material.","authors":"Njwan Fadhel Shehab, Hana Khaleel Ismail, Nadia H Hasan","doi":"10.2340/biid.v13.45749","DOIUrl":"10.2340/biid.v13.45749","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated the histopathological response of the dental pulp following direct pulp capping (DPC) using Mineral Trioxide Aggregate Repair High Plasticity (MTA Repair HP) supplemented with green-synthesized selenium nanoparticles (SeNPs). The objective was to determine how SeNP concentration influences the biological behavior of MTA HP and to identify the dose that best supports pulp healing compared with MTA HP alone.</p><p><strong>Methods: </strong>Twelve male dogs with 132 teeth were included. Twelve teeth served as negative controls, while 120 teeth were assigned to five groups: MTA HP alone or MTA HP combined with 0.5%, 1%, 1.5%, or 2% (w/w) SeNPs (<i>n</i> = 24 per group). Standardized pulp exposures were created and treated according to group allocation. Samples were collected at 7, 14, 30, and 60 days (<i>n</i> = 6 per interval) for histopathological assessment of inflammation, necrosis, and reparative dentine formation.</p><p><strong>Results: </strong>The group treated with 1% SeNP had the best results. They displayed very little inflammation, no signs of tissue necrosis, and started forming reparative dentine as early as day 14. While inflammation diminished over time in all the groups, the statistical analysis showed that the different SeNP levels made a difference in how much inflammation occurred, how much tissue necrosis there was, and the quality of the new dentine.</p><p><strong>Conclusion: </strong>Adding SeNP to MTA HP depended on the amount used. The 1% version presented the best biocompatibility and assisted pulp tissue heal better. On the other hand, higher amounts triggered more inflammation. Overall, these results recommend that 1% SeNP-enhanced MTA HP could be a choice for direct pulp capping, offering better healing and clinical results.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45749"},"PeriodicalIF":0.0,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of an angio-osseo inductive bone ceramic versus demineralised freeze-dried bone allograft in the treatment of periodontal intrabony defects: a randomised controlled clinical trial.","authors":"Vidya Sagar S, Uday Kiran Roopavath, Navatha Sattar, Raja Babu P, Athmuri Durga Nandini, Neema Kumari, Subha Narayan Rath","doi":"10.2340/biid.v13.45748","DOIUrl":"10.2340/biid.v13.45748","url":null,"abstract":"<p><strong>Introduction: </strong>Periodontal intrabony defects (IBDs) respond favourably to regenerative periodontal therapy. Various graft and non-graft materials have been used, with non-allogenic bone substitutes offering the potential to enhance clinical outcomes and radiographic defect resolution. Angio-Osseo Inductive Bone Ceramic (ABC), a novel ion-doped biphasic calcium phosphate graft, has shown promise due to its osteogenic and angiogenic potential.</p><p><strong>Aim: </strong>The study aimed to compare the clinical and radiographic outcomes of ABC and demineralised freeze-dried bone allograft (DFDBA) in the surgical management of periodontal IBDs.</p><p><strong>Materials & methods: </strong>A parallel-group, examiner- and statistician-blinded, randomised controlled clinical trial was conducted on 30 IBDs (one per patient), randomly assigned to ABC (test, <i>n</i> = 15) or DFDBA (control, <i>n</i> = 15). Clinical parameters, including Plaque Index (PI), Gingival Index (GI), probing pocket depth (PPD), and clinical attachment level (CAL), were recorded at baseline, 3 months, and 6 months. Radiographic bone fill was assessed at 3 and 6 months using standardised digital radiovisiography.</p><p><strong>Results: </strong>In both groups, mean IBD scores were significantly different at all time intervals (<i>p</i> < 0.05). Intergroup differences in PPD reduction and CAL gain were not statistically significant. Radiographic analysis demonstrated significantly greater bone fill in the test group (68.63%) compared with the control group (45.48%) at 6 months (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Both ABC and DFDBA were effective in the treatment of periodontal IBDs. However, ABC demonstrated statistically significant improvement in defect fill, supporting its potential as a novel alloplastic alternative to conventional allograft.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45748"},"PeriodicalIF":0.0,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of nano silver fluoride pre-treatment on the microtensile bond strength of a universal adhesive to dentin: an in vitro study.","authors":"Larissa Alexsandra Dos Santos Silva, Anna Caroline Lima Dos Santos, Luis Felipe Espíndola-Castro, Ana Luísa Cassiano Alves, Márcia de Almeida Durão, Maria Clara Müller de Andrade, André Galembeck, Gabriela Queiroz de Melo Monteiro","doi":"10.2340/biid.v13.45648","DOIUrl":"10.2340/biid.v13.45648","url":null,"abstract":"<p><strong>Objective: </strong>The study aims to evaluate the effect of Nano Silver Fluoride (NSF) pre-treatment at two concentrations on the microtensile bond strength (µTBS) of a universal adhesive to dentin.</p><p><strong>Methods: </strong>Flat deep coronal dentin surfaces from sound human molars were treated with NSF at 600 or 1500 ppm, or left untreated (control). A universal adhesive (Single Bond Universal; 3M ESPE/now Solventum) was applied in self-etch (SE) mode, followed by placement of a bulk-fill resin composite (Filtek Bulk Fill; 3M ESPE / now Solventum). Specimens were sectioned to obtain sticks (~1 mm²) and tested for µTBS using a universal testing machine (500 N load cell; 5 mm/min crosshead speed), considering the tooth as the experimental unit (<i>n</i> = 8). Group comparisons were performed using Welch's one-way Analysis of Variance (ANOVA). Weibull analysis was conducted on stick-level data (<i>n</i> = 56 per group) to assess bond strength reliability. Failure modes were evaluated under stereomicroscopy, and dentin morphology and silver nanoparticle distribution were qualitatively assessed using Scanning Electron Microscopy (SEM).</p><p><strong>Results: </strong>No statistically significant differences were detected among groups (<i>p</i> = 0.074). Mean µTBS values were 33.0 ± 10.2 MPa (control), 35.6 ± 8.7 MPa (NSF 600), and 21.4 ± 11.7 MPa (NSF 1500). Effect size analysis indicated a large effect associated with NSF concentration. Weibull analysis showed lower characteristic strength and Weibull modulus for the NSF 1500 group, indicating reduced bond reliability. Adhesive failures predominated in all groups.</p><p><strong>Conclusion: </strong>Although no statistically significant differences were detected, higher NSF concentration (1500 ppm) was associated with lower bond strength reliability, whereas the lower concentration (600 ppm) maintained favorable bonding performance. Greater accumulation of silver nanoparticles on the dentin surface may interfere with resin infiltration and hybrid layer formation.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45648"},"PeriodicalIF":0.0,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147625123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of plant fiber reinforcement on mechanical properties of PMMA denture base resin: a systematic review.","authors":"Muhammad Khawaja Hammad Uddin, Nazrah Mehar, Muhammad Ammar Khan, Muhammad Hassan Khoso, Bilquess Saba, Muneeb Ahmed Lone, Ayesha Akram, Syeda Mamoona Mateen, Muhammad Amber Fareed, Muhammad Sohail Zafar","doi":"10.2340/biid.v13.45632","DOIUrl":"10.2340/biid.v13.45632","url":null,"abstract":"<p><strong>Introduction: </strong>To improve the clinical outcomes and long-term durability of polymethyl methacrylate (PMMA) denture-based resins, they have undergone several developments and changes in their chemical composition to enhance their mechanical properties, including reinforcing them with natural fibers.</p><p><strong>Aim: </strong>This systematic review aimed to explore the influence of plant fiber reinforcement on the mechanical characteristics of PMMA denture resins.</p><p><strong>Material and methods: </strong>For this purpose, the formulated focus question was 'Does incorporating plant fibers in PMMA denture resins improve their mechanical strength?' Using the PRISMA protocol, three electronic databases (Google Scholar, Pub Med, and Science Direct) were searched using the specific keywords: (plant fibers, natural fibers, and PMMA denture base resins) between 2014 and 2024. After evaluating the papers against the inclusion criteria, only those that met all requirements were included in the study. Additionally, all articles were screened for quality assessment, with particular attention to potential bias arising from experimental design and methodological reporting.</p><p><strong>Results: </strong>This review included eight experimental laboratory-based studies that met the inclusion criteria. All studies had low risk of bias, except one, which had moderate risk of bias. The evaluation of reinforced resins' flexural strength was a noticeable trend observed in studies, with the maximum weight percentage utilized in the studies being 10 wt%. While flexural strength was primarily assessed by the majority of studies, other mechanical properties - including hardness, impact strength, tensile strength, and compressive strength - were also evaluated.</p><p><strong>Conclusions: </strong>The analysis revealed that the flexural strength and surface hardness of PMMA denture resins were significantly enhanced through the addition of plant fiber reinforcement. However, limited and inconclusive data are present for other mechanical properties (impact, compressive, and tensile strength). Extended experimental studies related to aging and various storage protocols, as well as clinical trials, are essential to determine its clinical relevance and longevity.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45632"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13044905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147625161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of cold atmospheric plasma alone or combined with conventional surface treatments on shear bond strength of 3Y-TZP and 5YSZ ceramics bonded with composite resin.","authors":"Ahmad Abdulkareem Alnazzawi, Mohamed F Aldamaty, Mohammed H AbdElaziz, Ahmed Yaseen Alqutaibi, Ahmed E Farghal, Jamal Qernas Almarashi, Abdel-Aleam H Mohamed, Muhammad Sohail Zafar","doi":"10.2340/biid.v13.45567","DOIUrl":"10.2340/biid.v13.45567","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the role of cold atmospheric plasma (CAP), alone or in combination with conventional surface treatments, on the shear bond strength (SBS) and failure mode of 3Y-TZP and 5YSZ ceramics bonded to composite resin using two adhesive protocols.</p><p><strong>Materials and methods: </strong>A total of 200 zirconia specimens (3Y-TZP and 5YSZ) were assigned to five surface-treatment groups: No treatment (control), airborne-particle abrasion (APA), CAP, APA + CAP, and hydrofluoric acid (HF) + CAP. Each group was further divided according to the use of a primer. The zirconia specimens were bonded to composite resin using a self-adhesive cement. After artificial aging, SBS testing and failure-mode analysis were performed. Data were analyzed using appropriate parametric tests (α = 0.05).</p><p><strong>Results: </strong>Compared with the control group, surface treatments significantly improved SBS (<i>p</i> < 0.001). Applying self-adhesive cement with surface primer further improved SBS (<i>p</i> < 0.001). Different yttria contents of zirconia materials did not impact SBS (<i>p</i> > 0.05). There was no benefit to combining APA and CAP or CAP and HF. Failure modes were predominantly adhesive in the control group and mixed on treated zirconia surfaces.</p><p><strong>Conclusions: </strong>CAP provides bond strength comparable to APA while potentially minimizing surface damage, supporting its use as a conservative surface-treatment option. Additional combined or aggressive surface treatments do not offer further clinical benefit for bonding zirconia restorations.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45567"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13044903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147625216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of HCl concentration and immersion time on physicochemical properties, BMP-2 detection, degradation, and osteoblast response of human demineralized tooth matrix.","authors":"Anupong Jeerachaipansakul, Narit Leepong, Srisurang Suttapreyasri","doi":"10.2340/biid.v13.45645","DOIUrl":"10.2340/biid.v13.45645","url":null,"abstract":"<p><strong>Objective: </strong>Human demineralized tooth matrix (hDTM) is a promising tooth-derived graft material; however, demineralization protocols vary widely and may alter matrix structure, degradation behavior, and growth factor detectability. This study investigates the combined effects of hydrochloric acid (HCl) concentration (0.5 vs 1.0M) and immersion time (10 vs 20 min) on the physicochemical characteristics, Bone Morphogenetic Protein-2 (BMP-2) detection, degradation behavior and osteoblast response of hDTM.</p><p><strong>Methods: </strong>Caries-free permanent teeth (particle size 500-1000 μm) were demineralized using four HCl protocols: 0.5M/10 min, 0.5M/20 min, 1M/10 min, and 1M/20 min. Morphology, crystallinity, and surface features were characterized by scanning electron microscopy (SEM), X-ray diffraction, X-ray fluorescence, and Brunauer-Emmett-Teller analysis. Total protein and BMP-2 were quantified using Bradford and enzyme-linked immunosorbent assay (ELISA) assays. In-vitro degradation was monitored for 60 days in simulated body fluid. MC3T3-E1 osteoblast adhesion and proliferation were evaluated using the SEM and PrestoBlue^® assay. Two-way analysis of variance was performed to assess main and interaction effects of concentration and time.</p><p><strong>Results: </strong>Both HCl concentration and immersion time significantly influenced hDTM properties. Lower concentration enlarged dentinal tubules and collagen exposure, whereas higher concentration produced surface microcracking and reduced collagen exposure. Higher HCl concentration increased degradation (1M/20 min: 23.76 ± 3.23% vs. 0.5M/20 min: 9.02 ± 0.63%, p < 0.01), while longer immersion increased ELISA-detected BMP-2 levels (1M/20 min: 11.8 ± 1.9 ng/g; 0.5M/20 min: 5.3 ± 1.6 ng/g vs. control: 0.1 ng/g, <i>p</i> < 0.001). Significant independent and interactive effects of HCl concentration and immersion time were observed (<i>p</i> < 0.001). Among the test conditions, a 0.5M/20 min protocol demonstrated balanced collagen preservation, controlled degradation, and favorable osteoblast proliferation.</p><p><strong>Conclusion: </strong>HCl concentration and immersion time independently and interactively modulate hDTM properties. Within the test conditions, 0.5M HCl for 20 minutes provides a practical solution and balances collagen preservation, controlled degradation, and osteoblast proliferation, supporting its use as a feasible approach for fabricating tooth-derived bone graft materials.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45645"},"PeriodicalIF":0.0,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147596139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of acetic acid and citric acid on calcium silicate based cement removal from root canals and their effect on dentine structure - an <i>in vitro</i> study.","authors":"Hanan Alzraikat, Ahmad S Al-Hiyasat, Estabraq Sarya Jamous, Mohammad A Alebrahim","doi":"10.2340/biid.v13.45669","DOIUrl":"10.2340/biid.v13.45669","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the effectiveness of acids on calcium silicate cement surface hardness, perforation, and their impact on root dentine microstructure.</p><p><strong>Materials and methods: </strong>Root dentine discs were exposed to hydrochloric, acetic, and citric acids. Fourier transform infrared spectroscopy (FTIR) assessed dentine microstructure after exposure to these acids. Sixty discs of Biodentine and NeoPUTTY (<i>n</i> = 30 each) were treated with 2% acetic acid, 5% citric acid, or saline (control), then tested for surface microhardness (Vickers hardness number, VHN). Another 60 dentine discs filled with these cements were exposed to the acids or saline and mechanically perforated with a Peeso reamer; perforation time was recorded. Scanning electron microscopy (SEM) examined dentine and cement surfaces.</p><p><strong>Results: </strong>FTIR revealed that hydrochloric acid caused severe demineralization of dentine microstructure, whereas 2% acetic and 5% citric acids had no significant effect on dentine microstructure. Both acids (acetic and citric) significantly reduced VHN compared to controls (<i>p</i> < 0.001). Acid-treated groups were perforated faster, with citric acid showing the greatest time reduction (<i>p</i> < 0.001). NeoPUTTY required less perforation time than Biodentine (<i>p</i> < 0.001). SEM revealed surface cracks in Biodentine and round-shaped defects in NeoPUTTY after acid exposure; citric acid opened dentinal tubules more distinctly than acetic acid.</p><p><strong>Conclusions: </strong>Acetic and citric acids significantly reduced microhardness and facilitated mechanical perforation of calcium silicate cements, with citric acid exerting greater effect.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45669"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13032180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of post-treatment complications of conventional composites versus self-adhering composites: a review.","authors":"Fatemeh Farshad, Erfan Eskandari, Marzieh Rohaninasab","doi":"10.2340/biid.v13.45223","DOIUrl":"10.2340/biid.v13.45223","url":null,"abstract":"<p><p>Self-adhering composites (SACs) are designed to simplify dental procedures by eliminating the need for separate adhesive systems. These materials are indicated for small Class I and Class V cavities, noncarious cervical lesions, and as liners in Class I and II restorations. Despite their advantages, the long-term durability and clinical performance of these composites compared to conventional composites (CCs) is a question. This study aims to compare post-treatment complications, including marginal adaptation, postoperative sensitivity, marginal discoloration, marginal gap, and microleakage, between CCs and SACs. In February 2024, a comprehensive search was conducted using PubMed, Google Scholar, Scopus, and Web of Science databases. No filters were applied during the search. Keywords included 'resin composite restoration', 'post-operative sensitivity', 'marginal adaptation', 'marginal gap', and 'microleakage'. Studies were selected based on inclusion criteria (clinical trials, English-language, focusing on SACs vs. CCs) and exclusion criteria (nonindexed studies, conference abstracts, editorials, case reports, review articles, or pre-2019 studies). From 361 articles, 148 remained after removing duplicates and title screening. Out of 148 records found in databases, six records were selected for this study. Data showed that SACs and CCs have comparable marginal adaptation, postoperative sensitivity, marginal discoloration, and retention in conservative restorations. SACs showed slightly higher microleakage in some cases. Overall, the clinical performance of SACs were comparable to that of CCs. Thus, SACs can be a practical alternative for simplifying restorative procedures. However, their potential for higher microleakage needs further investigation through long-term clinical studies.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45223"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13032179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of salivary pH variations on the adhesive performance of Transbond XT and Orthocem in orthodontic bracket bonding.","authors":"Lismory Karina Leiton Narváez, Marjory Elizabeth Vaca Zapata, Mauricio Aguirre Balseca, Karina Maria Salvatore Freitas, Yalil Rodríguez","doi":"10.2340/biid.v13.45568","DOIUrl":"10.2340/biid.v13.45568","url":null,"abstract":"<p><strong>Objective: </strong>This in vitro study aimed to evaluate the shear bond strength of orthodontic brackets bonded to acrylic resin specimens with two adhesive systems, Transbond XT and Orthocem, under different salivary pH levels (4, 5, 6, and 7).</p><p><strong>Materials and methods: </strong>A total of 120 acrylic resin specimens (Brava Block^®, FGM) were prepared and randomly assigned to three groups: control bonded with Transbond XT and Orthocem with no salivary exposure (<i>n</i> = 24), Transbond XT (<i>n</i> = 48), and Orthocem (<i>n</i> = 48). Each adhesive group was subdivided and immersed in artificial saliva at pH 4, 5, 6, or 7 for 30 days. Metal premolar brackets (Vector+ Roth prescription, Aditek^®) were bonded following manufacturers' protocols and subjected to shear bond strength testing using a Universal Testing Machine, following ISO 4049 standards. Data were analyzed with Analysis of Variance (ANOVA), <i>t</i>-test, and Tukey tests at a significance level of <i>p</i> < 0.05.</p><p><strong>Results: </strong>Transbond XT consistently showed higher bond strength than Orthocem across all pH levels. Maximum resistance was observed at pH 7 (21.19 ± 5.06 MPa), followed by the control group (19.64 ± 5.28 MPa). Orthocem demonstrated significantly lower values, ranging from 9.51 ± 3.87 MPa (pH 5) to 4.94 ± 2.15 MPa (pH 6). Acidic conditions reduced the bond strength of both adhesives, but Transbond XT maintained clinically reliable values, while Orthocem was more susceptible to performance decline at moderately acidic levels.</p><p><strong>Conclusions: </strong>Salivary pH directly influenced adhesive performance. Transbond XT demonstrated superior resistance under all conditions, whereas Orthocem showed lower but still clinically acceptable shear bond strength values, except at pH 6, where a marked decrease was observed.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45568"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13019279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of biological properties of bioactive glasses on enamel during artificial erosive tooth wear.","authors":"Dimitrios Dionysopoulos, Petros Mourouzis, Avraam Konstantinidis, Lambrini Papadopoulou, Kosmas Tolidis, Robert G Hill","doi":"10.2340/biid.v13.45670","DOIUrl":"10.2340/biid.v13.45670","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to evaluate the protective effect of air-abrasion with two bioactive glasses (BAGs) on enamel surface against erosion/abrasion challenge.</p><p><strong>Materials and methods: </strong>Thirty human third molars were collected, and enamel specimens were prepared and randomly assigned to three groups (<i>n</i> = 10): control group, where specimens received no treatment and BAG groups, where enamel was air-abraded once for 10 seconds with BioMinF® and ProSylc™, respectively. The operational parameters were: air pressure 20 psi, powder flow rate dial 1 g/min and nozzle-surface distance 5 mm. The samples were submerged in a 0.01 M HCl solution for 2 minutes and then placed in a remineralizing solution for 2 hours (five times daily). At the end of each day, the samples were stored in the remineralizing solution for 14 hours. Thirty minutes after the initial and final erosive challenges of the day, an abrasion challenge was conducted using an electric toothbrush. Erosive tooth wear (ETW) was evaluated by measuring enamel surface loss, while surface hardness and roughness were measured to provide an indirect assessment of ETW-related changes. Additional insights into the bioactivity of the treatments were obtained by analyzing alterations in enamel morphology and composition. The data were statistically analyzed using one-way Analysis of Variance (ANOVA).</p><p><strong>Results: </strong>BAG treatments significantly reduced surface loss (38.7-46.7%) and increased surface hardness (6.3-8.9%) and roughness in enamel (<i>p</i> < 0.05). No significant differences were observed between the two BAG treatments (<i>p</i> > 0.05). Alterations in enamel surface morphology and composition were detected in the BAG groups compared to the control.</p><p><strong>Conclusions: </strong>Air-abrasion treatment with BAGs can provide a protective effect against early ETW, particularly under conditions that simulate gastroesophageal reflux disease (GERD)-related defects. Clinically, this implies that BAG air-abrasion may serve as a minimally invasive preventive treatment for patients at high risk of ETW, such as those with GERD.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"45670"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13019126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}