Biological psychiatry global open science最新文献

{"title":"The Role of Awe and Other Psychological Factors in Ketamine’s Mechanism of Antidepressant Action","authors":"Mina Ansari, Gerard Sanacora","doi":"10.1016/j.bpsgos.2024.100353","DOIUrl":"10.1016/j.bpsgos.2024.100353","url":null,"abstract":"","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 5","pages":"Article 100353"},"PeriodicalIF":4.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667174324000661/pdfft?md5=924fa03072b6fb44d861a5f3b5ba472c&pid=1-s2.0-S2667174324000661-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142242523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Board Page","authors":"","doi":"10.1016/S2667-1743(24)00091-0","DOIUrl":"10.1016/S2667-1743(24)00091-0","url":null,"abstract":"","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 5","pages":"Article 100378"},"PeriodicalIF":4.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667174324000910/pdfft?md5=6a74f031fb574bfb7000fd1611e85e4f&pid=1-s2.0-S2667174324000910-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142242520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting Deep Structures to Noninvasively Modulate Fear and Anxiety","authors":"Odile A. van den Heuvel","doi":"10.1016/j.bpsgos.2024.100363","DOIUrl":"10.1016/j.bpsgos.2024.100363","url":null,"abstract":"","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 5","pages":"Article 100363"},"PeriodicalIF":4.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667174324000764/pdfft?md5=43def89ddc2febe61c7dd1e0fcdf8600&pid=1-s2.0-S2667174324000764-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142238736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subscribers Page","authors":"","doi":"10.1016/S2667-1743(24)00092-2","DOIUrl":"10.1016/S2667-1743(24)00092-2","url":null,"abstract":"","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 5","pages":"Article 100379"},"PeriodicalIF":4.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667174324000922/pdfft?md5=8a2165ec857ba0671393b030659b1bd9&pid=1-s2.0-S2667174324000922-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurobiological Underpinnings of Adolescent Susceptibility to Stress","authors":"Patricio O’Donnell","doi":"10.1016/j.bpsgos.2024.100364","DOIUrl":"10.1016/j.bpsgos.2024.100364","url":null,"abstract":"","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 5","pages":"Article 100364"},"PeriodicalIF":4.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667174324000776/pdfft?md5=1d3fff78f9f4487e8d581b0ac1ca8851&pid=1-s2.0-S2667174324000776-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142238737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative Schizotypy: Now That We Know What It Is, Should We Do Something About It?","authors":"Philip D. Harvey","doi":"10.1016/j.bpsgos.2024.100354","DOIUrl":"10.1016/j.bpsgos.2024.100354","url":null,"abstract":"","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 5","pages":"Article 100354"},"PeriodicalIF":4.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667174324000673/pdfft?md5=cb5e1b98eb5d0e69b1f2617a23648720&pid=1-s2.0-S2667174324000673-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142238734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guide for Authors","authors":"","doi":"10.1016/S2667-1743(24)00094-6","DOIUrl":"10.1016/S2667-1743(24)00094-6","url":null,"abstract":"","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 5","pages":"Article 100381"},"PeriodicalIF":4.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667174324000946/pdfft?md5=e4c107b2955882d1f85d260b960e176f&pid=1-s2.0-S2667174324000946-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142242521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Borderline Personality Disorder Symptoms and Stressful Life Events: An Evaluation of Gene-Environment Interplay","authors":"Vilde Sofie Arneberg ,&nbsp;Vilde Sundsvold ,&nbsp;Ludvig Daae Bjørndal ,&nbsp;Eivind Ystrom","doi":"10.1016/j.bpsgos.2024.100390","DOIUrl":"10.1016/j.bpsgos.2024.100390","url":null,"abstract":"<div><h3>Background</h3><div>Borderline personality disorder (BPD) is associated with high rates of stressful life events (SLEs). It is unclear whether people who experience SLEs have more BPD symptoms after accounting for the effects of familial risk factors. Our aims in the current study were to 1) create a predictive model of BPD using stressors across age and contexts and 2) examine whether SLEs resulted in higher levels of BPD symptoms beyond the effects of genetic and environmental risk factors.</div></div><div><h3>Methods</h3><div>The sample comprised 2801 twins from the Norwegian Institute of Public Health Twin Panel. Poisson regression was used to explore which SLEs predicted BPD symptoms. Elastic net penalized regression was conducted to develop a predictive model for SLEs and BPD symptoms. Co-twin control analyses were performed to differentiate between environmental and genetic factors.</div></div><div><h3>Results</h3><div>SLEs experienced during childhood and adulthood were associated with BPD symptoms. A weighted polyevent risk score explained 22% of the total variation in symptoms. Shared environmental and heritable factors explained 31% and 47% of individual differences in BPD symptomatology, respectively. Measured SLEs explained 42% of the shared environmental risk for BPD. The predictive risk of SLEs for BPD was reduced when shared environmental and genetic factors were accounted for. However, SLEs increased risk of BPD symptoms beyond the effects of shared genetic and environmental factors.</div></div><div><h3>Conclusions</h3><div>BPD symptomatology following SLEs cannot fully be explained by genetic and shared environmental factors. The SLE-BPD symptoms associations were primarily due to selection by family environments. It is important to identify familial factors that lead to both SLEs and BPD symptoms. SLEs remained associated with BPD symptoms beyond genetic and environmental confounding.</div></div>","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 6","pages":"Article 100390"},"PeriodicalIF":4.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142423051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Meta-Analysis of Anxiety- and Depressive-Like Behaviors in Rodent Models of Neuropathic Pain","authors":"Tomás de la Rosa ,&nbsp;Meritxell Llorca-Torralba ,&nbsp;Adrián Martínez-Cortés ,&nbsp;Cristina Romero-López-Alberca ,&nbsp;Esther Berrocoso","doi":"10.1016/j.bpsgos.2024.100388","DOIUrl":"10.1016/j.bpsgos.2024.100388","url":null,"abstract":"<div><h3>Background</h3><div>Epidemiological studies have frequently shown the concurrence of chronic pain with symptoms of anxiety and depression, particularly in women. Animal models are useful to understand the complex mechanisms underlying comorbidities, but the wide range of methods employed and the wealth of evidence sometimes impedes effective translation and reproducibility. In this systematic review and meta-analysis, we aimed to synthesize the evidence regarding the influence of variables such as sex and species on anxiety- and depressive-like behaviors in rodent models of neuropathic pain.</div></div><div><h3>Methods</h3><div>Following PROSPERO registration, we searched EMBASE, Scopus, and the Web of Science from their inception to November 24, 2023, identifying 126 studies that met the inclusion criteria. The Hedges’ <em>g</em> value for each experiment and study was calculated, and further subgroup and meta-regression analyses were performed.</div></div><div><h3>Results</h3><div>Neuropathic pain significantly reduced the time that rats and mice spent in the open arms of the elevated plus and zero mazes (<em>g</em> = −1.14), time spent in the center of the open field (<em>g</em> = −1.12), sucrose consumption in the sucrose preference test (<em>g</em> = −1.43), and grooming time in the splash test (<em>g</em> = −1.37) while increasing latency to feed in the novelty-suppressed feeding test (<em>g</em> = 1.59) and immobility in the forced swimming (<em>g</em> = 1.85) and tail suspension (<em>g</em> = 1.91) tests. Sex differences were observed, with weaker effects in female than in male rodents for several behavioral paradigms, and funnel plots identified positive publication bias in the literature.</div></div><div><h3>Conclusions</h3><div>This meta-analysis emphasizes the effect of neuropathic pain on anxiety- and depressive-like behaviors in rodents, highlighting the importance of investigating sex differences in future experimental studies.</div></div>","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 6","pages":"Article 100388"},"PeriodicalIF":4.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142422722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Mental Disorders in Donors and Matched Recipients of Hematopoietic Stem Cell Transplants: A Population-Based Cohort Study","authors":"Troels Boldt Rømer ,&nbsp;Henrik Sengeløv ,&nbsp;Rune Haubo Bojesen Christensen ,&nbsp;Michael Eriksen Benros","doi":"10.1016/j.bpsgos.2024.100389","DOIUrl":"10.1016/j.bpsgos.2024.100389","url":null,"abstract":"<div><h3>Background</h3><div>Immunological mechanisms have been implicated in the development of mental disorders, and interestingly, case reports have suggested that hematopoietic stem cell transplantation (HSCT) can both transmit and cure psychotic disorders by replacing immune progenitor cells.</div></div><div><h3>Methods</h3><div>Using Danish registers, we followed patients who received HSCT from donors with a psychiatric diagnosis or psychotropic medication use. We assessed risk of incident mental disorders or psychotropic medication use compared with recipients with unaffected donors. We identified 464 donor-recipient pairs (51.3% male recipients). All donor-recipient pairs were related.</div></div><div><h3>Results</h3><div>Receiving HSCT from a donor with a psychiatric history was not significantly associated with incident psychiatric diagnoses (hazard rate ratio [HRR] 2.79, 95% CI, 0.83–9.39; <em>p</em> = .098) or incident use of psychotropics (HRR 1.43, 95% CI, 0.91–2.24; <em>p</em> = .118). Subgroup analysis showed an increased risk of antipsychotic use, which remained significant after adjusting for confounders (HRR 4.73, 95% CI, 1.26–17.78; <em>p</em> = .021); however, this was based on a small number of cases. For depression and antidepressant use, data were available to perform a meta-analysis of our and one additional study, which showed no significant difference (HRR 1.24, 95%, CI 0.66–2.35).</div></div><div><h3>Conclusions</h3><div>Receiving HSCT from a donor with a psychiatric history did not affect risk of mental disorders. An increased risk of antipsychotic use was observed only in subgroup analyses; however, the exploratory nature of the study, the limited sample size, and family relationship between donors and recipients do not allow for causal conclusions, and external replication studies are warranted.</div></div>","PeriodicalId":72373,"journal":{"name":"Biological psychiatry global open science","volume":"4 6","pages":"Article 100389"},"PeriodicalIF":4.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142423104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}