Advanced Powder Technology最新文献_第10页

Selective pharmaceutical sensitization design based on amino acid metabolism: 5-fluorouracil-sarcosine cocrystal prepared by wet powder grinding method 基于氨基酸代谢的选择性药敏设计：湿粉研磨法制备的 5-氟尿嘧啶-肌氨酸共晶体

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-13 DOI: 10.1016/j.apt.2024.104514

Han Hao , Tiantian Ren , Cuilu Quan, Wei Guo, Jing Wang

{"title":"Selective pharmaceutical sensitization design based on amino acid metabolism: 5-fluorouracil-sarcosine cocrystal prepared by wet powder grinding method","authors":"Han Hao , Tiantian Ren , Cuilu Quan, Wei Guo, Jing Wang","doi":"10.1016/j.apt.2024.104514","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104514","url":null,"abstract":"<div><p>Pharmaceutical cocrystal is an emerging strategy not only to improve physicochemical properties, but also to generate synergistic effects. In this work, a novel cocrystal composed by 5-fluorouracil (5-FU) and sarcosine (SAR) was successfully assembled by wet powder grinding method. The cocrystal was characterized by single crystal X-ray diffraction (SCXRD), powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) and Raman spectra. The differences of <sup>1</sup>H NMR spectroscopy between 5-FU/SAR physical mixture (PM) and cocrystal hinted the existence of supramolecular interactions between 5-FU and SAR in solid and solution. Bioavailability of cocrystal was increased than 5-FU. Most importantly, the weak interactions between 5-FU and SAR in cocrystal solution induced the superior cellar inhibition activity on 4T1 and BEL-7402 cells compared than 5-FU and PM. Cocrystal can interfere with the stability of methionine cycle and tetrahydrofolate (FH<sub>4</sub>) level through the SAR-Gly-Met pathway, enhance the inhibition of thymidylate synthase (TS) compared to 5-FU, thereby interfering with cell cycle and inducing cell apoptosis. The results provided the novel strategy to develop the cocrystal drugs using bioactive amino acids as precursors to enhance the efficacy.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141326096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolution of sulfur species on malachite surfaces in the presence of calcium and magnesium ions and implications for xanthate flotation 钙镁离子存在时孔雀石表面硫物种的演变及其对黄原酸盐浮选的影响

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-13 DOI: 10.1016/j.apt.2024.104538

Xingcai Yu , Bin Yu , Han Wang , Peilun Shen , Dianwen Liu

{"title":"Evolution of sulfur species on malachite surfaces in the presence of calcium and magnesium ions and implications for xanthate flotation","authors":"Xingcai Yu , Bin Yu , Han Wang , Peilun Shen , Dianwen Liu","doi":"10.1016/j.apt.2024.104538","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104538","url":null,"abstract":"<div><p>The depletion of mining resources has led to a sharp increase in gangue minerals. The use of flotation technology with seawater, which is rich in Ca<sup>2+</sup> and Mg<sup>2+</sup>, has gradually increased. However, these ions may affect the flotation process. Herein, we study the effects of the addition of Ca<sup>2+</sup> and Mg<sup>2+</sup> on the process and products of malachite sulfidization. Analysis of the S layer on the mineral surface indicates that the quantities of S components generated on the malachite surface decrease in the presence of Ca<sup>2+</sup> and Mg<sup>2+</sup>. Additionally, Ca<sup>2+</sup> and Mg<sup>2+</sup> induce the excessive generation of oxidized S species (SO<sub>n</sub><sup>2−</sup>) during sulfidization, which inhibits the formation of Cu<sub>2</sub>S. Furthermore, both the solubility of malachite and the consumption of collector ions in the solution increase in the presence of Ca<sup>2+</sup> and Mg<sup>2+</sup>. Microflotation experiments confirm that Ca<sup>2+</sup> and Mg<sup>2+</sup> result in insufficient sulfidization properties on the malachite surface and reductions in the activity of the sulfidization products, leading to a decrease in sample floatability.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141326097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing large porous mannitol-leucine microparticles via spray drying technique 通过喷雾干燥技术优化大孔甘露醇-亮氨酸微颗粒

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-12 DOI: 10.1016/j.apt.2024.104512

Karnkamol Trisopon, Ornanong Suwannapakul Kittipongpatana, Phennapha Saokham

{"title":"Optimizing large porous mannitol-leucine microparticles via spray drying technique","authors":"Karnkamol Trisopon, Ornanong Suwannapakul Kittipongpatana, Phennapha Saokham","doi":"10.1016/j.apt.2024.104512","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104512","url":null,"abstract":"<div><p>The development of large porous microparticles (LPPs) has gained attention for dry powder in-halation (DPI) formulations due to their potential to enhance the efficiency of drug delivery into the lungs. In this work, large porous mannitol-leucine microparticles (MALs) were developed using a spray drying technique. Mannitol was co-spray dried with ammonium bicarbonate (0–50 % w/w) and leucine (1–20 % w/w). The morphology of MAL particles was spherical hollow with corrugated surface. The MAL with 10 % leucine (MAL-10) showed the lowest bulk density (0.08 g/cm<sup>3</sup>) with the highest surface area (7.85 m<sup>2</sup>/g), while the aerodynamic diameter (D<sub>aer</sub>) was within 1–5 μm, indicating the suitability to penetrate the lung. The DSC and XRD results indicated that the MALs exhibited a mixture of β- and α-polymorphs, while the FT-IR spectra con-firmed that no chemical interaction during co-processing. The leucine co-processing significantly improved powder flowability of the MAL-10 (28.33° for angle of repose). In addition, the co-processing with high leucine concentration (10–20 %) significantly reduced moisture sorption, while the polymorph of MALs did not change after 30 days of hygroscopicity study that indicated good stability. According to all results, the MALs could potentially be applied as drug carriers for DPI formulations.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-component mixing and demixing model for predictive finite element modelling of pharmaceutical powder compaction 用于药粉压实有限元预测建模的多组分混合和脱混模型

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-12 DOI: 10.1016/j.apt.2024.104513

Dingeman L.H. van der Haven , Maria Mikoroni , Andrew Megarry , Ioannis S. Fragkopoulos , James A. Elliott

{"title":"Multi-component mixing and demixing model for predictive finite element modelling of pharmaceutical powder compaction","authors":"Dingeman L.H. van der Haven , Maria Mikoroni , Andrew Megarry , Ioannis S. Fragkopoulos , James A. Elliott","doi":"10.1016/j.apt.2024.104513","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104513","url":null,"abstract":"<div><p>A set of numerical methods is described that allows predictive finite element method (FEM) simulations of the compaction of multi-component pharmaceutical powder formulations across the entire range of compositions. An automated parametrisation procedure was used to extract density-dependent Drucker-Prager Cap (dDPC) model parameters from experimental data. Subsequently, these parameters were interpolated (mixed) or extrapolated (demixed) to predict dDPC model parameters of unseen powder formulations. Pure, binary, and ternary formulations of micro-crystalline cellulose (MCC, plastic), dibasic calcium phosphate dihydrate (DCPD, brittle), and pre-gelatinised starch (STA, elastic) powders were used to validate the parametrisation and mixing/demixing methodologies. FEM simulations were capable of reproducing compaction curves with errors only marginally greater than the experimental variability. Using only pure component data, FEM simulations with mixing rules were capable of predicting the compaction curves of mixtures as well as their shear stress distributions. Moreover, with data of only two or three powder formulations, a new demixing methodology was able to predict the behaviour of the constituent powders. The combination of these methodologies provides a powerful tool to rapidly explore powder formulations anywhere within the composition phase diagram, providing compaction curves but also stress profiles that are essential to early-stage formulation process development and tooling design.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0921883124001894/pdfft?md5=345f2c8e3bcf89595a6d777990744a74&pid=1-s2.0-S0921883124001894-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of hydrochloric acid corrosion pretreatment on the flotation performance of hematite and its surface acid corrosion mechanism 盐酸腐蚀预处理对赤铁矿浮选性能的影响及其表面酸腐蚀机理

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-11 DOI: 10.1016/j.apt.2024.104515

Yu Xie , Xiaoqi Ban , Wanzhong Yin , Jin Yao

{"title":"The influence of hydrochloric acid corrosion pretreatment on the flotation performance of hematite and its surface acid corrosion mechanism","authors":"Yu Xie , Xiaoqi Ban , Wanzhong Yin , Jin Yao","doi":"10.1016/j.apt.2024.104515","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104515","url":null,"abstract":"<div><p>This study systematically investigated the impact of Hydrochloric acid (HCl) corrosion pretreatment on hematite flotation within the NaOL system, analyzing the influence of varying HCl concentrations (measured as pH) on hematite acid corrosion. The results showed that at pH = 1, after 4 min of acid corrosion, hematite exhibited optimal floatability, achieving a recovery rate of 82.49 %, significantly surpassing the original ore. Conversely, at pH = 5, after the same duration of acid corrosion, hematite’s flotation is inhibited, yielding a recovery rate of 59.38 %, lower than the original ore. Through contact angle, adsorption amount measurements, and AFM detection, it is observed that after corrosion in pH = 1 HCl solution, hematite surface roughness increases, more NaOL collector is adsorbed, leading to significant hydrophobicity enhancement. After corrosion in pH 5 weak acid environment, despite increased surface roughness, hematite surface was coated with particulate matter, greatly reducing NaOL adsorption and further decreasing hydrophobicity. Further analysis using FTIR, XPS, and hydrolysis component calculation indicated that after acid corrosion in HCl at pH = 1, hematite exposed more active Fe sites, enhancing flotation performance. Conversely, at pH = 5, surface-dissolved Fe<sup>3+</sup> transformed into hydrophilic Fe(OH)<sub>3</sub>, inhibiting flotation by covering the hematite surface.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141303327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental study on the influence of water immersion on the wettability of coal dust 浸水对煤尘润湿性影响的实验研究

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-10 DOI: 10.1016/j.apt.2024.104504

Lingfeng Wang , Shixun Ding , Zhengdong Liu , Kaiwen Sun , Zhiyang Zhang , Chang Li , Chunmiao Yuan

{"title":"Experimental study on the influence of water immersion on the wettability of coal dust","authors":"Lingfeng Wang , Shixun Ding , Zhengdong Liu , Kaiwen Sun , Zhiyang Zhang , Chang Li , Chunmiao Yuan","doi":"10.1016/j.apt.2024.104504","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104504","url":null,"abstract":"<div><p>In order to enhance the understanding of the wetting mechanism of coal dust and explore additional approaches to improve the wettability of hydrophobic coal dust. Two coal dust samples with different particle sizes were selected and subjected to water immersion treatments. The wetting behavior of coal dust was investigated through a sinking experiment, focusing on the effects of the water immersion process, immersion time, and particle size. Fourier-transform infrared spectroscopy was employed to analyze the changes in functional groups of coal dust during the water immersion process. The results indicated a significant improvement in the wettability of coal dust after a short-term water immersion treatment, and this enhancement effect can be synergistic with the action of surfactants. The increase in hydroxyl content was identified as a crucial factor in enhancing the wettability of coal dust after water immersion. Moreover, the limitations of using the fractal dimension of particle size distribution to characterize the wettability of coal were explored. The results indicated that coal dust with similar fractal dimensions could exhibit significant differences in wettability, suggesting the need for further investigation into the effects of particle size polydispersity and other particle size parameters on coal dust wettability.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141303326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Separate recycling of iron and aluminum from iron-rich red mud by coal gangue reduction to realize solid waste utilization 通过煤矸石还原从富铁赤泥中分离回收铁和铝，实现固体废弃物利用

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-08 DOI: 10.1016/j.apt.2024.104506

Bai Zhe , Han Chang , Yuan Shuai , Li Xinyu

{"title":"Separate recycling of iron and aluminum from iron-rich red mud by coal gangue reduction to realize solid waste utilization","authors":"Bai Zhe , Han Chang , Yuan Shuai , Li Xinyu","doi":"10.1016/j.apt.2024.104506","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104506","url":null,"abstract":"<div><p>Iron-rich red mud is a typical solid waste in the aluminum industry. And coal gangue is generated during the coal selection process. The efficient treatment of these two kinds of large reserves of solid waste has important resource value and environmental value. In this study, the co-roasting of iron-rich red mud with coal gangue for iron and aluminum recycling was explored. The optimum conditions were 850 °C, 30 min, 30 % coal gangue, −37 μm accounts for 85.88 %, and magnetic intensity of 132 × 10<sup>3</sup>A/m. Then the iron recovery, TFe grade, iron yield, Al<sub>2</sub>O<sub>3</sub> content of iron concentrate were 70.14 %, 59.77 %, 49.14 %, and 8.26 %, separately. the Al<sub>2</sub>O<sub>3</sub> content and recovery rate in Al-containing products were 16.90 %, and 64.35 %, separately. Based on the analysis of materials, hematite was transformed to magnetite, and diaspore was transformed into Al<sub>2</sub>O<sub>3</sub> through co-roasting. Its saturation magnetization strength increased from nearly 0 A·m<sup>2</sup>·kg<sup>−1</sup> to 7.23 A·m<sup>2</sup>·kg<sup>−1</sup>. Meanwhile, the sample changed from compact to porous honeycomb structure, and the newly formed small magnetite particles were densely distributed on the surface. Therefore, the co-roasting achieved tailings-free resource utilization of two types of solid waste, as well as co-roasting to effectively separate iron and aluminum from red mud and coal gangue.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141292104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental study on the distribution of multi-size sinter and void fraction in the sinter vertical tank 烧结垂直罐中多尺寸烧结矿分布和空隙率的实验研究

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-08 DOI: 10.1016/j.apt.2024.104501

Shuo Wang , Baokuan Li , Shaopei Duan , Wenjie Rong

{"title":"Experimental study on the distribution of multi-size sinter and void fraction in the sinter vertical tank","authors":"Shuo Wang , Baokuan Li , Shaopei Duan , Wenjie Rong","doi":"10.1016/j.apt.2024.104501","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104501","url":null,"abstract":"<div><p>Sinter segregation leading to non-uniform distribution of multi-size sinter and void fraction is a common problem during the operation of the sinter vertical tank. In order to study the segregation of sinter in the vertical tank and the distribution of void fraction when the sinter was not uniformly distributed, a experimental apparatus with a ratio of 1:10 to the field apparatus was established. In this paper, a self-made spacing plate was used to measure the segregation and void fraction distribution more accurately for large, medium, and small grain sizes sinter in vertical tank at three height levels. It was found that the distribution of 15 ∼ 20 mm sinter was more at the corners of the vertical tank, and less under the feeding ducts. And the distribution of 0 ∼ 1.5 mm sinter was opposite to 15 ∼ 20 mm sinter. While 5 ∼ 8 mm sinter was more uniformly distributed. In addition, the void fraction gradually increased with the height of the sinter layer. In the horizontal direction, the largest void fraction was found at the corners of the vertical tank, while the smallest under the feeding ducts. The results of the study help to validate different mathematical models.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141292102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An experimental investigation on oleaster (Elaeagnus angustifolia L.) low-fibrous extract drying kinetic with maltodextrin 麦芽糊精对油桐（Elaeagnus angustifolia L.）低纤维提取物干燥动力学的实验研究

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-08 DOI: 10.1016/j.apt.2024.104509

Sajad Jabari Neek , Hojat Ghassemi , Mohammad Javad Ziabakhsh Ganji , Mohammad Kamalinejad

{"title":"An experimental investigation on oleaster (Elaeagnus angustifolia L.) low-fibrous extract drying kinetic with maltodextrin","authors":"Sajad Jabari Neek , Hojat Ghassemi , Mohammad Javad Ziabakhsh Ganji , Mohammad Kamalinejad","doi":"10.1016/j.apt.2024.104509","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104509","url":null,"abstract":"<div><p>The escalating demand for oleaster in the food and pharmaceutical industries has intensified research on the drying process of oleaster low-fibrous extract (OLFE). This study focuses on preventing sticky particle formation during drying by incorporating maltodextrin (MD) as a drying aid, elevating the glass transition temperature of particles. Different OLFE:MD blends were synthesized under glass transition temperatures analysis, and the drying process was explored using the single droplet drying method at different environmental temperatures. Additionally, water-MD mixtures without OLFE were examined to unravel the solo MD’s drying kinetics. The optimal OLFE:MD ratio of 1:3 or higher resulted in non-sticky dried particles, exhibiting a reduced drying time compared to pure OLFE. Remarkably, initial solid concentration minimally affected drying at 150 °C, while at 200 °C, highly concentrated droplets encountered delays due to crust quality. Notably, the final particle size aligned with the initial droplet diameter.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141294127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on induced airflow law of grab unloading based on CFD-DEM 基于 CFD-DEM 的抓斗卸荷诱导气流规律研究

IF 5.2 2区工程技术

Advanced Powder Technology Pub Date : 2024-06-08 DOI: 10.1016/j.apt.2024.104510

Yuechang Song, Mingxu Wang

{"title":"Study on induced airflow law of grab unloading based on CFD-DEM","authors":"Yuechang Song, Mingxu Wang","doi":"10.1016/j.apt.2024.104510","DOIUrl":"https://doi.org/10.1016/j.apt.2024.104510","url":null,"abstract":"<div><p>Grab bucket unloading is an important link in the process of grain transportation in ports, and the airflow changes caused by particle movement are a key influencing factor causing dust overflow. At present, there are few studies on the induced airflow changes during grab unloading. This article uses the CFD-DEM coupling method to study the effects of two major factors, mass flow rate and drop height, on the induced airflow. The results show that under this model, the induced airflow velocity increases with the increase of mass flow rate and drop height, and the power exponents of the fitting curve are about 0.25 and 0.44, respectively. Among the two major factors, the drop height plays a dominant role, When the mass flow rate is small (model 2.14 Kg/s in this article), the impact of the change in drop height on the induced airflow velocity is relatively small. As the mass flow rate increases, the impact of drop height increases. Based on the dimensional analysis method and combined with the simulation results, the empirical formula of the induced airflow velocity is established, which can provide a reference for the structural design of the port dust funnel.</p></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":null,"pages":null},"PeriodicalIF":5.2,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141292103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0