Advanced Powder Technology最新文献

{"title":"Mangifera indica phytochemical enriched ZnO-Amphotericin B Nanoconjugates: Enhanced hydrophilicity, reduced toxicity and pH-sensitive release for targeted anti-Candida therapy","authors":"Divya Mathew ,&nbsp;Benny Thomas ,&nbsp;N.M. Sudheep ,&nbsp;Surya Nair ,&nbsp;E.K. Radhakrishnan","doi":"10.1016/j.apt.2025.104895","DOIUrl":"10.1016/j.apt.2025.104895","url":null,"abstract":"<div><div>Amphotericin B (AmB) faces limitations in antifungal applications due to toxicity and poor solubility. This study developed AmB conjugate with green-synthesized zinc oxide nanoparticles (gZnONPs) using <em>Mangifera indica</em> leaf extract (MLE) to enhance pH sensitivity and hydrophilicity. FTIR analysis confirmed AmB conjugation and MLE phytocore on the surface of the gZnONPs, while UV–Vis spectroscopy showed a red shift from 362 to 394 nm after AmB conjugation, indicating successful binding. The conjugate showed increased solubility from 0.31 to 125 µg/mL and enhanced hydrophilicity (contact angle reduced from 53° to 34°). The enhanced saturation solubility might be due to NP size effects, reduced crystallinity, phytochemical-induced hydrophilicity, and effective drug encapsulation, collectively improving the bioavailability and therapeutic efficacy of AmB at the target site. The AmB release profile showed pH-sensitive, sustained release, with higher rates at infection-site (pH 5.5), ensuring prolonged therapeutic effects. Antifungal tests demonstrated significant zone of inhibition for the conjugate (47 mm) against <em>Candida albicans</em>, outperforming MLE (34 mm), AmB (41 mm) and ZnONPs (37 mm) alone. The conjugate showed 2.4-fold higher LC₅₀ (446.51 μg/mL) over AmB (186.39 μg/mL), suggesting reduced toxicity, likely due to phytochemical capping minimizing non-specific interactions with healthy cells and pH-sensitive, targeted release. Further, the hemolysis study demonstrated that ZnONPs significantly reduced AmB-induced RBC lysis (4.1 % at 24 h vs. 18.1 % for pure AmB), outperforming lipid-based formulations (9–14 %), highlighting their potential as a safer nanocarrier for AmB delivery while mitigating dose-dependent hemolysis. These findings highlight the potential of gZnONPs as an effective nanocarrier for AmB, offering enhanced solubility, targeted antifungal activity, and reduced toxicity, making it a promising alternative to conventional formulations.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104895"},"PeriodicalIF":4.2,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double perovskite of Ca3WO6 supported Ni-based catalysts for hydrogen production via auto-thermal reforming of acetic acid","authors":"Jianhong Li ,&nbsp;Qi Chen ,&nbsp;Mao Gan ,&nbsp;Jinbo Liu ,&nbsp;Ying Su ,&nbsp;Lihong Huang","doi":"10.1016/j.apt.2025.104888","DOIUrl":"10.1016/j.apt.2025.104888","url":null,"abstract":"<div><div>Acetic acid (HAc) derived from biomass is a rich resource for production of green hydrogen via auto-thermal reforming (ATR), while Ni-based catalysts for ATR of HAc are hindered by concerns of coke deposition, oxidation and sintering of active components. Herein, Ni-Ca-W-O catalysts with double perovskite structure were prepared by the Pechini method and employed in ATR reaction. The characterization results indicated that phase of Ca₃WO₆ with double perovskite structure was formed via introducing W species into CaO phase, while oxygen defect sites and abundant oxygen vacancies were found and effective to constrain coke deposition during ATR. Furthermore, with Ni species entering the Ca₃WO₆ lattice, there was strong interaction within Ni/Ca₃WO₆, forming stable Ni-Ca-W-O active centers with improved resistance to either oxidation or sintering of Ni⁰. As a result, the preferred Ni_0.08Ca_0.32W_0.07O_0.61±δ catalyst maintained high HAc conversion at 100 % and H₂ yield near 2.52 mol-H₂/mol-HAc, showing potential for hydrogen production via ATR of HAc.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104888"},"PeriodicalIF":4.2,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facile synthesis of silver loaded bioactive glass ceramic and reinforced composite scaffold using acrylic polymer for bone tissue engineering applications","authors":"K. Venkatesan ,&nbsp;Kotikalapudi Sreeramachandra Karthik ,&nbsp;Ann Mary Mathew ,&nbsp;P.V. Sreya ,&nbsp;Sarada P Mallick ,&nbsp;Deepak K. Pattanayak","doi":"10.1016/j.apt.2025.104892","DOIUrl":"10.1016/j.apt.2025.104892","url":null,"abstract":"<div><div>Bioactive glasses are mainly used in tissue engineering applications such as fabrication of resorbable scaffolds, bioactive composite bone cements, etc., as they release Na⁺, Ca²⁺, Mg²⁺, PO₄^3- ions, which aid in repairing and regenerating damaged tissues. The inability of fabricated composite scaffolds or bone cements to impart antimicrobial activity may lead to bacterial infection and other inflammatory responses. This work attempted to develop acrylic polymer and bioactive glass composite bone cement with antibacterial activity. Initially, bioactive glass powders were synthesized by a simple sol–gel method with different concentrations of silver (Ag) to induce antibacterial properties. The physicochemical properties, like thermal stability and phase change, etc. with respect to the concentration of Ag loading were evaluated. The results showed that no significant structural and compositional change occurred due to heat treatment and the amorphous phase could be maintained upto 700°C. Electrochemical analysis (Differential Pulse Voltammetry) of bioactive glass in simulated body fluid showed the peak current signifying the gradual release of Ag⁺ ions. The released Ag⁺ ions from the bioactive glass powders showed inhibition against Gram-positive <em>Staphylococcus aureus</em> and Gram-negative <em>Escherichia coli</em> bacterial systems. The cytocompatibility study of Ag-loaded bioactive glasses in MG-63 human osteoblast like cell lines showed no toxic effect for all the concentration ranges attempted. The developed Ag-loaded bioactive glass powder with optimum antimicrobial property and good cell viability was subsequently used as reinforcement in Poly Methyl Methacrylate (PMMA) matrix to develop porous composite scaffold using porogen leaching technique. Mechanical study (compression test) proved that the fabricated scaffolds have sufficient rigidity, and the thermal degradation phenomenon could be controlled by the addition of bioactive glass powders to the PMMA matrix. This interconnected porous scaffold with good bioactivity, antimicrobial property, mechanical rigidity and cell compatibility is expected to be potent in bone tissue engineering applications.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104892"},"PeriodicalIF":4.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of particle compositions on screening performance: Modeling and prediction via data segmentation approach","authors":"Jinpeng Qiao,&nbsp;Yanze Wang,&nbsp;Jinshuo Yang,&nbsp;Wei Wang,&nbsp;Chenlong Duan","doi":"10.1016/j.apt.2025.104901","DOIUrl":"10.1016/j.apt.2025.104901","url":null,"abstract":"<div><div>Variations in particle composition along the screen pose significant challenges for modeling screening dynamics. This study examines the influence of feeding conditions on screening efficiency through a segmental approach and investigates various machine-learning algorithms for predictive modeling. Segmentation and transformation of passing rate curves were clearly observed and discussed. A novel algorithm was developed to predict screening efficiency for screens of varying lengths, and a method for segmenting simulated data for machine learning modeling is proposed. Results show that the mass content of easy-to-sieve particles affects segmental screening efficiency oppositely to that of difficult-to-sieve particles. Specifically, increasing the mass content of easy-to-sieve particles narrows the crowded screening region while enhancing overall screening efficiency. For particles of different sizes, K-Nearest Neighbors Regression, Multilayer Perceptron Regression, and Support Vector Regression provide effective prediction models. For screens of varying lengths, Support Vector Regression outperforms the others, achieving an average deviation of less than 3%.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104901"},"PeriodicalIF":4.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-depth analysis of surface selective adsorption and interfacial mechanisms in the efficient flotation separation of magnesite and dolomite with the environmentally friendly inhibitor baicalin","authors":"Xiaoqi Ban ,&nbsp;Jin Yao ,&nbsp;Wanzhong Yin ,&nbsp;Taozhong Zhang ,&nbsp;Wenju Sun ,&nbsp;Weifan Du ,&nbsp;Yulian Wang","doi":"10.1016/j.apt.2025.104903","DOIUrl":"10.1016/j.apt.2025.104903","url":null,"abstract":"<div><div>Due to the similarities in crystal structure and chemical composition, the surface electric properties, wettability, and interfacial characteristics of magnesite and dolomite are highly similar, posing significant challenges in flotation separation. This study investigates the selective inhibition mechanism of the environmentally friendly depressant baicalin (BA) on dolomite in a sodium oleate (NaOl) flotation system, focusing on interfacial behavior control. Micro-flotation tests showed successful separation of magnesite and dolomite under optimal reagent conditions (pH 10.0, BA concentration of 60 mg/L, NaOl concentration of 120 mg/L). Zeta potential and contact angle measurements indicated that BA increased the negative charge on dolomite and significantly reduced its hydrophobicity, with minimal impact on magnesite. FTIR and XPS analyses revealed strong chemisorption of BA’s hydroxyl groups on calcium sites of dolomite, with weaker affinity for magnesium sites. AFM imaging showed a notable increase in the surface roughness of dolomite after BA treatment, further confirming selective adsorption. A flotation separation model was developed based on micro-flotation and characterization results, shedding light on the separation mechanism and the differences in surface adsorption and interfacial behavior of magnesite and dolomite.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104903"},"PeriodicalIF":4.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of acoustic agglomeration enhanced by solid seed particles using the DSMC method","authors":"Junxu Su ,&nbsp;Zhihao Wu ,&nbsp;Fengxian Fan ,&nbsp;Xiaohong Hu ,&nbsp;Mingxu Su","doi":"10.1016/j.apt.2025.104902","DOIUrl":"10.1016/j.apt.2025.104902","url":null,"abstract":"<div><div>Acoustic agglomeration enhanced by large-sized solid seed particles is investigated using the direct simulation Monte Carlo (DSMC) method. The process of acoustic agglomeration is revealed in terms of temporal evolution of velocities, diameters, and number weights of simulated particles, as well as normalized concentration and average diameter of small particles. Furthermore, the enhancement of acoustic agglomeration by the solid seed particles is evaluated at varying parameters. The results show that the agglomeration performance is enhanced within a shorter residence time when the solid seed particles are present. Increasing acoustic intensity or solid seed particle concentration leads to more efficient acoustic agglomeration, while the acoustic frequency, particularly beyond 2 kHz, has little effect on agglomeration performance. Moreover, a noticeable increase in agglomeration efficiency is observed when the seed particle diameter increases from 20 to 40 µm. However, once it exceeds 40 µm, the increase in agglomeration efficiency diminishes.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104902"},"PeriodicalIF":4.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural, thermal, and optical properties of Dy3+/K+ Co-Doped SmCa4O(BO3)3 phosphors synthesized by Sol-Gel method","authors":"Abeer S. Altowyan ,&nbsp;H. Aydin ,&nbsp;U.H. Kaynar ,&nbsp;M.B. Coban ,&nbsp;Jabir Hakami ,&nbsp;P.D. Townsend ,&nbsp;N. Can","doi":"10.1016/j.apt.2025.104905","DOIUrl":"10.1016/j.apt.2025.104905","url":null,"abstract":"<div><div>This study investigates the structural, thermal, and optical properties of Dy³⁺/K⁺ co-doped SmCa₄O(BO₃) ₃ (SmCOB) phosphors synthesized using a sol–gel method. X-ray diffraction (XRD) analysis confirmed the high crystallinity and phase purity of the SmCOB lattice. Rietveld refinement further detailed slight lattice parameter modifications induced by Dy³⁺ and K⁺ doping. Fourier-transform infrared (FTIR) spectroscopy identified characteristic vibrational modes of the SmCOB matrix, including symmetric and asymmetric B–O stretching vibrations. These modes remained largely unaltered after doping, indicating the structural stability of the host lattice. Photoluminescence (PL) studies excited at 369 nm identified Dy³⁺ emission peaks at 468 nm (blue), 574 nm (yellow), and a dominant 657 nm (⁴F_9/2 → ⁶<em>H</em>_11/2). Co-doping with K⁺ increased the PL intensity by 26 %, attributed to charge compensation, reducing non-radiative losses and optimizing the local crystal field around Dy³⁺ ions. Luminescence decay analysis revealed that the Dy³⁺-doped sample exhibited a longer lifetime component (456.6 μs) compared to the undoped sample. Furthermore, K⁺ co-doping led to a significant increase in the average lifetime (752.8 μs), suggesting a further reduction in non-radiative decay pathways. Temperature-dependent PL analysis demonstrated excellent thermal resistance, with a high activation energy (<span><math><mrow><msub><mi>E</mi><mi>a</mi></msub></mrow></math></span> = 0.258 eV) for K⁺ co-doped samples, highlighting their suitability for high-power lighting applications. Chromaticity measurements positioned the phosphors in the cold white light region, demonstrating their potential for energy-efficient lighting and advanced display technologies.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104905"},"PeriodicalIF":4.2,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of a new oxygen lance to improve molten pool multi-phase flow characteristics with optimization based on numerical simulations","authors":"Haowei Yan ,&nbsp;Jun Chen ,&nbsp;Chao Li ,&nbsp;Xiaoli Su ,&nbsp;Pengyue Guo ,&nbsp;Xizhong An ,&nbsp;Hao Zhang","doi":"10.1016/j.apt.2025.104896","DOIUrl":"10.1016/j.apt.2025.104896","url":null,"abstract":"<div><div>In this study, a new type of ring seam-hole converter oxygen lance based on the jet convergence phenomenon is proposed to enhance the mixing efficiency in the converter smelting process. Firstly, by comparing with the published data from water model experiment, the accuracy of the Euler-Euler numerical model in simulating the top-blowing stirring process of the converter is validated. Then, the effects of different width ratios and flow ratios of ring seam to the hole on the flow characteristics and wall erosion of the molten pool are systematically studied. The simulation results show that the new ring seam-hole converter oxygen lance can effectively improve the mixing efficiency and reduce wall erosion. With the increase of the width ratio of ring seam to hole, the mixing time first decreases, then increases and then decreases. At the same time, the wall erosion first decreases and then increases, and the optimal width ratio is 1:10 after comprehensive consideration. In addition, with the increase of flow ratio, the mixing time gradually decreases, and the wall erosion first decreases, then gently increases. Considering the wall erosion and mixing efficiency comprehensively, the optimal flow ratio is determined to be 1:12. Finally, the flow characteristics of the molten pool under the combined action of bottom-blowing bubble plume and top-blowing jet are studied, which can effectively improve the flow characteristics of molten pool. The results of this paper are helpful to understand the multiphase flow characteristics in converter and the mechanism of the bubble flow field in gas and liquid phases, and provide theoretical support for improving converter smelting efficiency and prolonging converter service life.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104896"},"PeriodicalIF":4.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the flame propagation characteristics and mechanism of polyethylene dust deflagration suppressed by basic carbonates","authors":"Jin Han ,&nbsp;Fei Wang ,&nbsp;Jinshe Chen ,&nbsp;Yansong Zhang ,&nbsp;Shengjing Dongye ,&nbsp;Haiyan Chen ,&nbsp;Yang Zhang ,&nbsp;Yuzhen Zhu","doi":"10.1016/j.apt.2025.104884","DOIUrl":"10.1016/j.apt.2025.104884","url":null,"abstract":"<div><div>This paper investigates the potential of basic copper carbonate (BCC) and basic zinc carbonate (BZC) as explosion suppressants for polyethylene (PE) dust deflagration, aiming to improve accident prevention and control. Specifically, this study examines the inhibitory effects and mechanisms of these substances on the flame propagation of PE dust. The effects of the two suppressants on the speed, time, and acceleration of PE flame propagation were compared through Hartmann tube experiments. The findings demonstrate that increasing the quantity of suppressant markedly reduces the rate of flame propagation. This effect is particularly evident when 60 wt% of BZC is introduced, resulting in near-complete suppression. BZC shows a stronger suppression effect compared to BCC, primarily attributable to its lower decomposition temperature, which facilitates earlier release of inert gases during the deflagration process, thereby inhibiting flame spread. Further analysis of the explosion products using FTIR and SEM revealed that the suppressants achieve flame inhibition through a dual mechanism of physical cooling and chemical free radical scavenging. Additionally, numerical simulations using CHEMKIN PRO demonstrated that the inert gases produced by the decomposition of BZC can effectively capture H and OH free radicals generated during combustion, reduce flame temperature, and inhibit chain reactions.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104884"},"PeriodicalIF":4.2,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deformation and breakup of droplets of stabilized coal slime fuels interacting with an air jet","authors":"O.V. Vysokomornaya ,&nbsp;R.S. Volkov ,&nbsp;G.V. Kuznetsov ,&nbsp;P.A. Strizhak","doi":"10.1016/j.apt.2025.104887","DOIUrl":"10.1016/j.apt.2025.104887","url":null,"abstract":"<div><div>This research presents the experimental data on the influence of stabilizing additives on deformation and fragmentation behavior of waste-derived slurry droplets during their interaction with an air jet. The average radii and number of child droplets formed as a result of droplet breakup were recorded. The influence of the air jet velocity and the diameter of the parent droplet on the average radius and the number of secondary droplets was determined. The experiments demonstrated a dynamic change in the number and average radii of secondary droplets for different relative velocities of the parent slurry droplets. When adding a stabilizing additive to coal-water slurry, the number of secondary droplets decreased several times. Experimental data were analyzed using dimensionless criteria and deriving equations to predict the breakup characteristics of droplets of stabilized fuels over a wide range of air jet velocity. Maps of modes of droplet deformation and breakup were developed, plotted in coordinate systems using Weber, Reynolds, Ohnesorge and capillarity numbers.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104887"},"PeriodicalIF":4.2,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}