Archives of nephrology and urology最新文献

{"title":"Nonlinear Relationship between Systolic Blood Pressure and Diabetic Retinopathy in Type 2 Diabetic Patients in Southern China: A Single-Center Observational Study","authors":"isheng Luo, Chen Zhang, Chaochao Zhou, Zhisong Yan,, Zezhong Ouyang, Wenbin Zhu, Zhiyin Chen, Hao Wu","doi":"10.26502/anu.2644-2833071","DOIUrl":"https://doi.org/10.26502/anu.2644-2833071","url":null,"abstract":"Systolic blood pressure (SBP) has been shown to have a positive correlation with diabetic retinopathy (DR). However, the SBP thresholds have not been standardized for DR prevention. We analyzed data from a cross-sectional study (December 2017-November 2018, n = 426, mean age 59.15±13.68) from the Department of Endocrinology, Guangdong Provincial People's Hospital in patients with type 2 diabetes mellitus. DR severity was assessed by retinal photographs. The International Clinical Diabetic Retinopathy and Diabetic Macular Edema Disease Severity Scale was used to classify DR severity and divide it into two groups: with DR and without DR. SBP was analyzed as a continuous variable. Multivariate logistic regression models, smoothed curve fitting, threshold analysis, and interaction tests were used to assess the relationship between BP and DR. Prevalence of DR in the study population was 39.20%. After adjusting for age, sex, DM duration, HbA1c, BUN, HDL, LDL, TRIG, CHOL, TP, DBP, PP, eGFR, and CKD stage, the association between SBP and DR appears as a threshold effect, with a inflection point of 132mmHg. The risk of DR did not change significantly when SBP ≤132mmHg (OR: 0.86; 95% CI: 0.63 to 1.17, p=0.3400). When SBP ≥132mmHg, each 10 mmHg increase in SBP raise the risk of developing DR by 28% (OR:1.28; 95% CI:1.07 to 1.54, P=0.0081). In addition, a stronger association of SBP with DR in patients with TP≤60g/L (OR=1.58, 95% CI: 1.19- 2.08, P=0.001) compared to those with TP>60g/L (OR=1.15, 95% CI: 1.03, 1.27, P=0.012) was discovered, with a P value for interaction=0.023.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134889427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of SGLT2 Inhibitors in Peritoneal Dialysis Patients: a Shade of Light on Dapagliflozin","authors":"Abdullah K Alhwiesh, Ibrahiem Sarah Al-Wa, Saeed Abdul-Rahman, Mohammed Ahmad Nasreldin, Abdelgalil Moaz Mohammed, Suzan Al-Oudah, Reem Al-Thwainy, Ayat AlAwal, Zahra Alsenpisi, Abdullah Abdulrahman","doi":"10.26502/anu.2644-2833047","DOIUrl":"https://doi.org/10.26502/anu.2644-2833047","url":null,"abstract":"Nephrology Division, Department of Internal Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Saudi Arabia Department of Electrical Engineering, Queen’s University, Toronto, Kingston, Canada Infectious Disease Division, Department of Internal Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Saudi Arabia Department of pathology Dammam Central Hospital, Saudi Arabia","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Lower Urinary Tract Symptoms and Emotional State among a Sample of Clinic Attendees of a Tertiary Care Center in Central Sri Lanka","authors":"Pethiyagoda Aub, P. K, Ariyasinghe Di, W. S., Dimiyawa Km, Wijethunga Tm","doi":"10.26502/anu.2644-2833046","DOIUrl":"https://doi.org/10.26502/anu.2644-2833046","url":null,"abstract":"Introduction: Lower Urinary Tract Symptoms (LUTS) is a set of symptoms that correlates to the human urinary tract. Among the many reasons associated with LUTS, numerous studies have shown an association between LUTS and the emotional state of patients. Various researches in different Arch Nephrol Urol 2021; 4 (4): 143-150 DOI: 10.26502/anu.2644-2833046 Archives of Nephrology and Urology 144 geographical locations have been conducted to assess this relationship between LUTS and mental health in different ways. Findings from previous studies were highly dependent on the methodologies and criteria used. The purpose of this study is to evaluate any relationship between LUTS and the emotional state of patients in a sample of clinic attendees of General Urology (GU) clinic in Teaching Hospital, Peradeniya, Sri Lanka where the emotional state is assessed through criteria for depression, anxiety and stress. Here, International Prostate Symptom Score (IPSS) is used as the screening tool to evaluate LUTS and Depression Anxiety Stress Scale-21 (DASS-21) is used to quantify the emotional state. Methodology: This is a descriptive, cross-sectional study performed among patients attending the GU clinic at Teaching Hospital Peradeniya, Sri Lanka to identify the relationship between LUTS and the emotional state. Study samples were collected from July 2020 to October 2021. Subjects were asked questions using a questionnaire on the presence of Lower Urinary Tract Symptoms and the emotional state. Data analysis was performed using SPSS version 20. The association between IPSS and DASS-21 scores was analyzed using simple linear regression analysis. Results: The study group consisted of 161 patients who attended the GU clinic at the Teaching Hospital, Peradeniya. 84.5% of the sample was male while 15.5% was female. The mean age of the studied group was 62 ± 14.51 (p<0.005). The highest prevalent symptom was nocturia (81%). The mean total IPSS score was approximately 17. Among 161 patients 36.17%, 50.35% and 30.5% people had mild – extremely severe depression, anxiety and stress respectively. According to the coefficients of linear regression analysis, the most significant correlation was observed among LUTS and depression (p = 0.001). When IPSS score was increased by 1, depression score is predicted to be increased by .292. Similarly, when IPSS score was increased 1, anxiety score is predicted to be increased by .221 (p = 0.003) and stress score is predicted to be increased by .257 (p = 0.008). Conclusion: A clear association of stress with the LUTS was observed in a sample of 161 patients attending the GU clinic at Teaching Hospital, Peradeniya. The most prevalent LUT symptom was nocturia. Anxiety was the most prevalent emotional issue out of stress, anxiety and depression. Maximum correlation was observed among depression and LUTS with a higher significance.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penile Fracture: Diagnosis and Management of 13 Cases at Zinder National Hospital (Hnz)","authors":"H. M, K. A, Magagi A, Zakou Arh, Roua M","doi":"10.26502/anu.2644-2833051","DOIUrl":"https://doi.org/10.26502/anu.2644-2833051","url":null,"abstract":"Objective: The objective of this study was to report our experience of the management of penile fracture at the Zinder National Hospital (NIGER). Patients and methods : This is a retrospective, descriptive study of 13 cases of penile fracture treated in the urology department of Zinder National Hospital between February 2014 and June 2021. The parameters studied were patient age, circumstances of occurrence, marital status, clinical signs, treatment, and outcome. Results: The average age of our patients was 33 years old with extremes of 19 years and 51 years, there were 12 married patients, 3 of whom were on their wedding night, and 1 was single. The circumstances of occurrence were coitus for all patients. The interrogation found the use of erectogenic drugs by the 12 married patients. The classic coitus misstep was found in 9 cases, the other 4 admitting that it was the woman above who ended up crushing the penis. All was 7 hours with extremes of 12 and 46 hours. Surgical treatment was suture of the tunica albuginea of the corpus cavernosum through a coronal incision 11 cases and an elective incision in 2 cases. The mean follow-up was 18 months (range 4-24 months) before being completely lost of view. Three complications were recorded including a curvature, an albuginea nodule interfering with sexual intercourse, and one case of erectile pain. Conclusion: Penile fracture is a rare andrological emergency which must be treated quickly. In Africa, the admission delay is often long due to apprehension of genital organs pathology.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69345093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological, Therapeutic and Evolutive Aspects of Bladder Cancer in Douala","authors":"Jean Paul Engbang, H. Moby, Falonne Daoudou Soumaï, B. Amougou, Makon Nwaha, M. Ngowe Ngowe","doi":"10.26502/anu.2644-2833048","DOIUrl":"https://doi.org/10.26502/anu.2644-2833048","url":null,"abstract":"Bladder cancer can be defined as the uncontrolled proliferation of bladder cells, leading to the formation of a heterogeneous lesion. These bladder cells have variable sizes with no clear boundaries and potential to invade or spread to other parts of the body. This pathology is ranked second among genito-urinary cancers after prostate cancer. Our goal is to study the epidemiological, therapeutic and evolution aspects of bladder cancer in three hospitals in the city of Douala. Methodology: We carried out a descriptive study on the medical files of the patients during a period of 10 years, of the bladder, chemotherapy coupled with radical surgery play an important role in the treatment of bladder cancer. The global survival rates would be greatly improved if the availability and harmonization of treatment modalities were at the center of patient management. Also, studies on prognostic factors would facilitate a better identification of factors associated to the survival of patients with bladder cancer.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"De Novo versus Relapse of Glomerulonephritis Post COVID-19 Vaccination: Case Series in a Single Center in Saudi Arabia","authors":"A. A., Alayoobi L, I. M., Nasreldin M, A. M, Aljenaidi H, M. W., A. M, A. A., A. S., S. K., A. K, Almarri Z, Alquraish K","doi":"10.26502/anu.2644-2833045","DOIUrl":"https://doi.org/10.26502/anu.2644-2833045","url":null,"abstract":"The development of de novo or relapse of an already existing glomerular disease has been reported in association with some COVID-19 vaccinations, specifically the mRNA vaccines. Although reported cases are sparse and the number of reported cases are considered low in comparison to the total number of administered vaccine doses worldwide, the healthcare providers as well as the patients should be aware about such a serious complication in order to provide prompt and proper management. Here we report 3 cases of glomerular diseases in relation to COVID-19 vaccination. One case of IgA nephropathy, a case of IgA Arch Nephrol Urol 2021; 4 (4): 135-142 DOI: 10.26502/anu.2644-2833045 Archives of Nephrology and Urology 136 vacuities and nephropathy and a case of a relapse of a minimal change disease.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Socioeconomic Status with Glomerular Diseases at a Tertiary Care Hospital in Bangladesh","authors":"Kabir Me, Bashar A, Hu Mo, Azim Mau, Karim Anme, Hossain Rm, Faroque Mo, J. F, Hossain Mk, Rahman Akms","doi":"10.26502/anu.2644-2833053","DOIUrl":"https://doi.org/10.26502/anu.2644-2833053","url":null,"abstract":"Background: Social deprivation is a well-known risk factor for chronic kidney disease (CKD), however its association with glomerular diseases is less well understood. This study was aimed to evaluate the association of Socioeconomic Status (SES) with glomerular diseases among patients attending at a tertiary care hospital in Bangladesh. Methods: This cross sectional study was conducted at Department of Nephrology, Shaheed Sheikh Abu Naser Specialized Hospital, Khulna, Bangladesh from January 2016 to December 2020. A total of 184 diagnosed patients of glomerulonephritis (GN) were enrolled. Patient’s socioeconomic status (SES) was assessed using Modified BG Prasad socioeconomic classification. Morphological pattern of glomerular diseases were assessed according to the histopathology report. Relationship of glomerular diseases with particular socioeconomic status (SES) was identified. Results: Among 184 study patients 99 were male and 85 were female, their mean age was 31.18 ± 13.55 years. It was observed that, in proliferative variety; Mesengial Proliferative Glomerulonephtis (Mes PGN) was the leading morphological variant (34.7%) followed by Membranoproliferative Glomerulonephtis [MPGN (16.8%)], Lupus Nephritis [LN (7.1%)], Focal Segmental Proliferative Glomerulonephritis [FSPGN (7.1%)], IgA Nephropathy (6.5%), IgM Nephropathy (4.3%) and Crescentic Glomerulonephtis [Cres GN (2.2%) serially. In the non-proliferative glomerulonephtis; Membranous Nephropathy (MN) was the commonest form (10.9%) followed by Focal Segmental Glomerulosclerosis [FSGS (7.6%)] and Minimal Change Disease [MCD (2.7%)]. All types of GN were significantly prevalent in the lower socioeconomic classes (Class- III, IV, V), while the frequency of Mes PGN and MPGN were significantly higher in Class- IV and Class- V socioeconomic classes. Conclusion: Lower socioeconomic classes are associated with a higher incidence of glomerular diseases particularly Messangial Proliferative Glomerulonephritis (Mes PGN) and Membranoproliferative Glomerulonephritis (MPGN) in Bangladesh.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69345099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of Risk Factors of Malnutrition in Maintenance Hemodialysis Patients","authors":"N. Mali, J. Ge, F. Su, ChangYan Li, Wen-ring Fan","doi":"10.26502/anu.2644-2833049","DOIUrl":"https://doi.org/10.26502/anu.2644-2833049","url":null,"abstract":"This article reviews the iatrogenic (nutrient loss caused by dialysis, inflammatory reaction caused by dialysis, insufficient dialysis, and metabolic acidosis) and noniatrogenic (patients' insufficient diet, taste change, poor appetite, and psychosocial function) risk factors for malnutrition in maintenance hemodialysis patients. The aim of this review article is to incorporate these aspects into the malnutrition risk assessment of maintenance hemodialysis patients in order to enhance nutritional status, improve medical quality, and assure patient safety.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69345046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reticulocyte Haemoglobin Content (CHr) is a Reliable Marker of Iron Deficiency in Pre-dialytic Chronic Kidney Disease (CKD) Patients","authors":"Hu Mo, Hossain Rm, Alam Mr, Rahman Akms, Hasan Mk, Ahammod T, Haque Ms, S. Azm, I. T, Ahsan Mk","doi":"10.26502/anu.2644-2833050","DOIUrl":"https://doi.org/10.26502/anu.2644-2833050","url":null,"abstract":"Chronic kidney disease (CKD) is a non-communicable epidemic disease. The CKD patients suffer from various types of anemia including iron deficiency anemia. Measurement of reticulocyte hemoglobin content (CHr) has been proposed as a measure of available iron stores. In this study CHr and serum iron profile were compared with stainable iron in the bone marrow to evaluate the CHr as a marker of iron deficiency in pre-dialytic CKD patients. This cross sectional study was conducted at the Department of Nephrology, from January 2018 to December 2018. A total of seventy (70) pre-dialytic CKD patients were selected. All participants had undergone bone marrow study for detection of iron deficiency anemia and it was observed that, 60% CKD patients had iron deficiency by bone marrow iron stain. Serum iron profile [serum iron, total iron binding capacity (TIBC), serum ferritin, transferin saturation (TSAT)] and reticulocyte haemoglobin content (CHr) of each patient were determined accordingly. Data analysis reveals that CHr was significantly low in iron deficient group (p<0.001). The sensitivity and specificity of CHr at a cut-off 28 pg/cell was 81% and 75.0% respectively (p<0.001); sensitivity and specificity of serum ferritin at a cut-off 100 ng/ml was 40.6% and 67.9% respectively (p=0.051); while sensitivity and specificity of TSAT at a cut-off 20% was 54.2% and 57.1% respectively (p=0.465). The study proves that reticulocyte haemoglobin content (CHr) is a reliable marker to assess iron status for pre-dialytic CKD patients.","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69345059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Arham Purushakar Meditation on overall well-being of Patients with Chronic Kidney Disease on Hemodialysis","authors":"S. Kothari, A. Kothari, Shehnaz Sultana, P. Reddy","doi":"10.26502/anu.2644-2833044","DOIUrl":"https://doi.org/10.26502/anu.2644-2833044","url":null,"abstract":"Background: Meditation has been considered as a potential intervention to relieve stress, depression and anxiety in patients with chronic kidney disease on hemodialysis. Taking it into consideration, the present study is taken up to know the impact of Arham purushakar meditation on the overall well-being of patients with chronic kidney disease on hemodialysis. Material and Methods: 175 chronic kidney disease patients on hemodialysis were selected as the base line cases and a follow up of 12 months, 17 months and 21 months is done, to know the impact of Arham purushakar meditation on the overall well-being of the hemodialysis patients. The study was carried out after taking the approval of the Ethics Committee of Bhagwan Mahavir Medical Research Centre, and written consent from the patients for participation in the study. Arch Nephrol Urol 2021; 4 (3): 128-134 DOI: 10.26502/anu.2644-2833044 Archives of Nephrology and Urology 129 Results: The results showed significant decrease in depression, anxiety and stress in hemodialysis patients practicing Arham purushakar meditation, and also improvement in other physical and medical conditions. Conclusions: The results evidently showed significant improvement in psychological, medical and physical conditions in chronic kidney disease patients on hemodialysis practicing Arham purushakar meditation, confirming that the meditation is an effective complementary therapy for patients undergoing","PeriodicalId":72287,"journal":{"name":"Archives of nephrology and urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}