Annals of 3D printed medicine最新文献

{"title":"Feasibility of additively manufacturing synthetic bone for sports personal protective equipment applications","authors":"Gemma Leslie ,&nbsp;Keith Winwood ,&nbsp;Andy Sanderson ,&nbsp;Peter Zioupos ,&nbsp;Tom Allen","doi":"10.1016/j.stlm.2023.100121","DOIUrl":"10.1016/j.stlm.2023.100121","url":null,"abstract":"<div><p>Human limb surrogates, of varying biofidelity, are used in the performance assessment of sports personal protective equipment (PPE). Such biofidelic surrogates have incorporated soft tissue simulants (silicones) and synthetic bone (short fibre filled epoxy). Testing surrogates incorporating realistic synthetic bone could help to further our knowledge of fracture trauma mechanics, and applications such as the effectiveness of sports PPE. Limb surrogates with embedded synthetic bone are rarely tested to fracture, mainly due to the effort and cost of replacing them. This paper proposes additive manufacturing of synthetic bones, with appropriate bone like fracture characteristics, potentially making them more accessible and cost effective. A Markforged® X7™ printer was used as it prints a base filament (Onyx™) alongside a continuous strand of reinforcement (e.g., carbon fibre). The properties of specimens from this printer vary with the type, volume fraction and position of reinforcement. Bar specimens (10 × 4 × 120 mm) with varying amounts of carbon fibre reinforcement were printed for three-point bend testing to determine the feasibility of achieving mechanical properties close to compact bone (bending modulus of ∼15 GPa, bending strength of ∼180 MPa). Bending strength for the various bar specimens ranged from 32 to 378 MPa, and modulus values ranged from 1.5 to 25.8 GPa. Based on these results, four 140 mm long oval shaped cylindrical specimens of ø14 and ø16 mm were printed to represent a basic radius bone model. Three-point bend testing of these bone models showed similar bending modulus (3.8 to 5.3 GPa vs. 3.66 to 14.8 GPa) to radius bones reported in the literature, but higher bending strength (147 to 200 MPa vs. 80.31 ± 14.55 MPa).</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"12 ","pages":"Article 100121"},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43782158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in Glenoid and Coracoid Dimensions evaluated through 3D Printed bone models in the context of Anterior Shoulder Instability Surgery – An exploratory study","authors":"Vitor La Banca ,&nbsp;Ana Victoria Palagi Viganó ,&nbsp;Luiz Giglio ,&nbsp;Guilherme Henrique Vieira Lima ,&nbsp;Henrique de Lazari Schaffhausser ,&nbsp;Luiz Fernando Michaelis ,&nbsp;Roberto Yukio Ikemoto","doi":"10.1016/j.stlm.2023.100122","DOIUrl":"10.1016/j.stlm.2023.100122","url":null,"abstract":"<div><h3>Introduction</h3><p>Nonrecognition of smaller bone anatomy in the context of the Latarjet procedure may increase the chance of complications and worsen it outcomes, and this should be addressed preoperatively by accurate measuring of bone anatomy. Measurement of bone dimension can be performed through 3d printed bone models nowadays and therefore we aimed to evaluate glenoid and coracoid process dimensions obtained in 3D printed bone models, assess differences between genders, and compare the results with previously published anatomical studies. We hypothesized that the values obtained in the 3D models would be similar to those previously reported in other anatomical studies and gender differences would also be present.</p></div><div><h3>Methods</h3><p>We retrospectively retrieved shoulder computer tomography scans from 39 adult patients with uninjured scapula. Using the DICOM file of the CT, we performed three-dimensional reconstructions of the scapula, including the glenoid and coracoid. The resulting digital model was then printed in an FDM technology 3D printer. With the 3D Printed models, one of the authors measured the models using a digital caliper. The measurements collected on the Glenoid were Glenoid Superior-Inferior length (GlenSI); and Glenoid Antero-Inferior length (GlenAP) .On the coracoid, the measurements collected were the Coracoid Anterior-Posterior length (CoracAP), the Coracoid Medial-Lateral (CoracML) distance and the Coracoid Superior-Inferior (CoracSI) distance. Those measurements were summarized and underwent statistical comparison between genders. The results were compared with other anatomical studies in the same bone anatomy.</p></div><div><h3>Results</h3><p>We recorded a mean glenoid length (GlenAP) of 28.03 mm (SD = 0.45) and mean glenoid height (GlenSI) of 37,18 mm (SD =0,55). The mean glenoid dimensions differ significantly between male and female gender (p=0,002 and p=0,001, respectively).The coracoid mean length was 22,35 mm (SD=0.47), mean coracoid width was 14,97 mm (SD=0,30), mean coracoid height was9,51 mm (SD=0,22), and those measures also differ significantly between genders. The observed mean values were similar to those previously reported in other anatomical studies.</p></div><div><h3>Discussion</h3><p>We observed that coracoid and glenoid dimensions significantly vary between genders for all of the measurements performed. Measurements obtained in this series are comparable with other similar anatomic studies. Although some limitations exists in our study, we consider 3D-printed bone models in the setting of anatomical studies as a relevant option to traditional cadaveric studies.</p></div><div><h3>Conclusion</h3><p>Gender differences in coracoid and glenoid dimensions were observed and must be considered for the Latarjet procedure. Our results suggest that 3d printed bone models may be used for such evaluation with a good degree of reproducibility of the measurements observed in already publish","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"12 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41452424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semi-solid extrusion 3D-printing of eucalypt extract-loaded polyethylene oxide gels intended for pharmaceutical applications","authors":"Oleh Koshovyi ,&nbsp;Jyrki Heinämäki ,&nbsp;Ivo Laidmäe ,&nbsp;Niklas Sandler Topelius ,&nbsp;Andriy Grytsyk ,&nbsp;Ain Raal","doi":"10.1016/j.stlm.2023.100123","DOIUrl":"10.1016/j.stlm.2023.100123","url":null,"abstract":"<div><p>In pharmaceutics, 3D printing is considered as a promising future technology for fabricating more complex patient-specific drug delivery systems (DDSs). An anti-staphylococcal herbal preparation, “Chlorophyllipt”, is produced mainly in a liquid form by the pharmaceutical industry in Ukraine, and it is composed of an ethanolic eucalypt extract (EE). Since staphylococcal infections have become a true challenge for the health care in all over the world, it would be relevant and justified to develop the aqueous gels of the present EE applicable for the 3D printing of the corresponding solid DDSs. The aim of the present study was to develop a novel polyethylene oxide (PEO) gel loaded with EE for a semi-solid extrusion (SSE) 3D printing and to print the corresponding oral solid DDSs with different sizes and shapes. For SSE 3D printing, we prepared and tested total ten (10) different aqueous PEO gel formulations loaded with EE. Prior to 3D printing, the physical appearance, homogeneity, injection force and viscosity of the gels were investigated. The EE-PEO gels were printed to lattice- and round-shaped solid DDSs with the head speed of 0.5 mm/s, and the weight (mass uniformity) and effective surface area of the printed systems were determined. The most feasible EE-PEO gel for SSE 3D printing comprised of 10 mg/ml of EE, 30 mg/ml of eumulgin and 20 mg/ml of ascorbic acid in a 20-% aqueous PEO gel. The key process parameters of the SSE 3D printing were identified and verified. The printing quality of EE-PEO DDSs were very good, thus showing compatibility of a plant extract and carrier polymer. Such 3D-printed antimicrobial DDSs can be used for example in the treatment of skin wounds and infections of the oral cavity.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"12 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44366454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical implementation of 3D printed plesiotherapy moulds using free open source software","authors":"Luis Ángel Quiñones Rodríguez ,&nbsp;Joaquín Pérez Pavón ,&nbsp;Ignacio Castro Ramírez ,&nbsp;Lucía Gutiérrez Bayard ,&nbsp;Maria Amparo Iborra Oquendo","doi":"10.1016/j.stlm.2023.100124","DOIUrl":"10.1016/j.stlm.2023.100124","url":null,"abstract":"<div><h3>Purpose</h3><p>From May 2021 the European regulation EU2017/745 covers the manufacture of medical devices in healthcare facilities under certain conditions. In this context, the use of 3D printing and free software can be combined to provide a solution to some of the problems for which no commercial product can be found in brachytherapy.</p><p>What we present here is a procedure for the design, using open source software, and manufacture, with Fused Deposition Modeling technology, of brachytherapy surface moulds.</p></div><div><h3>Material and methods</h3><p>The procedure starts with a CT scan of the patient treatment area with radiopaque markers. 3D slicer software is then used to delimit the applicator mould that follows the patient's surface. After this, we use the Freecad software to design the channels where we will insert the plastic tubes through which the radiation source will deliver the treatment. We also use the Meshmixer software to make the final delimitation of the applicator edges as well as to find and correct any inconsistency.</p></div><div><h3>Results</h3><p>Moulds created by means of 3D printing allow us to combine the precise fit to the patient's surface of homemade solutions with the geometric accuracy between catheters of commercial products. This is clearly seen when treating small and irregular surfaces such as the ear pinna.</p></div><div><h3>Conclusion</h3><p>Manufacture of brachytherapy surface moulds with FDG technology is a good example of customized solutions in healthcare facilities supported by new European legistation. If we add to this the use of free open source software, we are facing an alternative to classics solutions used up to now in superficial brachytherapy.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"12 ","pages":"Article 100124"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43346756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspective approaches of 3D printed stuffs for personalized nutrition: A comprehensive review","authors":"Hemananthan Eswaran ,&nbsp;Renuka Devi Ponnuswamy ,&nbsp;Rajesh Pungampalayam Kannapan","doi":"10.1016/j.stlm.2023.100125","DOIUrl":"10.1016/j.stlm.2023.100125","url":null,"abstract":"<div><p>Food printing technology is going to be the promising technology of future. Advances in 3D food Printing or additive manufacturing technology adds extra dimension to the established food practices and offer opportunities for new interactive experiences. This paper aims to deliver the central flow of 3D food printing process and extends to summarize its knowledge towards the perception of personalized nutrition. The initial flow emphasizes the broad categories of food printing materials and further, to stream the concept of personalized nutrition, a unique attention is focused on latest technological innovations in the 3D printed foodstuffs with different nutritional approaches viz., nutrition enhancement, minerals/vitamins fortification, functional ingredients enrichment and the development of alternative foods. In addition to current prominent scientific researches, literature stuffing adds a new flavor drawing attention on several industrially developed 3D food printed products that are reached and inline to the market. A prominent highlight was embarked on recent technical progress in the development of pharma foods, insect and plant based meat alternatives using 3D printing techniques. It is strongly believed that personalization and customization of 3D printed foods could be a future talk in compromising, unsatisfied nutritional problems and eradicating several chronical diseases in the pandemic era.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"12 ","pages":"Article 100125"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48998632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary assessment on the effects of line width, layer height and orientation on strength and print time for FDM printing of total contact casts for the treatment of diabetic foot ulcers","authors":"Niall Mulcahy ,&nbsp;Kevin J. O'Sullivan ,&nbsp;Aidan O'Sullivan ,&nbsp;Leonard O'Sullivan","doi":"10.1016/j.stlm.2023.100115","DOIUrl":"10.1016/j.stlm.2023.100115","url":null,"abstract":"<div><p>The application of 3D Printing (3DP) for use in fracture casts and orthopaedic splints has been explored in several studies. The challenge of 3D printed casts is their size and relatively long production time compared to traditional/fibreglass casts. This preliminary study aims to determine the effects of three specific parameters specifically in the context of manufacturing Total Contact Casts (TCCs) for the treatment of diabetic foot ulcers.</p><p>The effects of printing parameters have been evaluated previously in the literature. However, there are little data in single experiments on layer height ratio dependent on line width; typically, lower values of layer height have been assessed that remain constant with all line widths. The combination of line width, layer height and print orientation have been evaluated here, with a focus on achieving quickest possible print time without sacrificing part strength in the context of 3D printed TCCs.</p><p>Flexural testing was conducted on FDM-printed PLA test specimens with 36 different treatments, adjusting the above parameters. The relationship between part strength (flexural modulus and maximum flexural stress) and print time was investigated.</p><p>It was determined that a low layer height could be paired with a high line width to achieve optimal part strength, considering also print time. The specific application, and associated direction of forces/loads is an important consideration when selecting a print orientation to optimise mechanical performance. A case example applied to the printing of a TCC is also presented.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"11 ","pages":"Article 100115"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48376933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current use of 3D printing in plastic surgery","authors":"Yannis CLAUDIC ,&nbsp;David A. ZOPF ,&nbsp;Melis OZKAN ,&nbsp;Remi DI FRANCIA ,&nbsp;Weiguo HU","doi":"10.1016/j.stlm.2023.100119","DOIUrl":"10.1016/j.stlm.2023.100119","url":null,"abstract":"<div><p>Since the 1980s, 3D printing has considerably broadened its field of application. Although only recently developed, there are now several techniques that allow the custom design of 3D objects. Plastic surgery, with its wide range of surgical indications, also benefits from the various 3D printing techniques. It brings a precious help to the surgeon, whether it is within the framework of pre-operative planning, of the custom design of cutting tools in maxillofacial surgery, or within a pedagogical framework with the learning of surgical techniques to students or for the provision of more precise information to patients. This work first recalls the different modalities of three-dimensional printing, then describes the main uses of 3D printing in plastic surgery.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"11 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44308150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D printed twin block: A feasibility study","authors":"Eryn Ling Yi Chan ,&nbsp;Yi Lin Song ,&nbsp;Kelvin Weng Chiong Foong ,&nbsp;Ming Tak Chew","doi":"10.1016/j.stlm.2023.100118","DOIUrl":"10.1016/j.stlm.2023.100118","url":null,"abstract":"<div><h3>Aims</h3><p>Twin blocks are appliances used for Class II skeletal discrepancies, where the lower jaw is positioned more posteriorly compared to the upper. The conventional method of fabrication of this appliance is tedious and labour-intensive; hence this study intends to explore the feasibility of a digital workflow to three-dimensionally (3D) print them.</p></div><div><h3>Methods</h3><p>Three sets of twin blocks, identical except for amount of offset (0.0 mm, 0.1 mm and 0.2 mm), were designed and 3D printed for 5 anonymized scans of patients with Class II skeletal discrepancies. The intaglio surfaces of the 0.0 mm offset twin blocks were scanned and superimposed onto their original computer-aided-design files. The resultant colour maps, root mean square (RMS) deviations, and percentage in-tolerance values at thresholds of 0.1 mm and 0.2 mm were assessed. The fit and retention of all twin blocks were assessed on their 3D printed models via a fit and retention score (FRS).</p></div><div><h3>Results</h3><p>The median RMS deviation was 0.10 mm; percentage in-tolerance values at thresholds of 0.1 mm and 0.2 mm were 79.90%, and 94.51%. Printing deviations occurred most often at labial and incisal edges anteriorly, and buccal and occlusal surfaces posteriorly. There was no significant difference between the total FRS for the three groups (<em>p</em> = 0.076). However, the frequency of satisfactory scores for upper fit (<em>p</em> = 0.049), lower fit (<em>p</em> = 0.018), upper retention (<em>p</em> = 0.038) and lower retention (<em>p</em> = 0.015) differed significantly between the three groups.</p></div><div><h3>Conclusion</h3><p>This study demonstrated the viability of a digital workflow to 3D print twin blocks. Print accuracy was satisfactory, with 0.1 mm offset providing the best fit and retention.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"11 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44432314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biometrics and three-dimensional alignment of the acromioclavicular joint. A biomechanical proof of concept study using the “reversed cadaver model”(RCM)","authors":"Marius Junker ,&nbsp;Milad Farkhondeh Fal ,&nbsp;Jörn Kircher","doi":"10.1016/j.stlm.2023.100114","DOIUrl":"10.1016/j.stlm.2023.100114","url":null,"abstract":"","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"11 ","pages":"Article 100114"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48689250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic arch repair in chronic dissection using 3D-printing planning","authors":"Paolo Magagna,&nbsp;Michele Gallo,&nbsp;Loris Salvador","doi":"10.1016/j.stlm.2023.100116","DOIUrl":"10.1016/j.stlm.2023.100116","url":null,"abstract":"<div><p>During imaging follow-up, the residual dissection after a type A repair dissection could progress and may require repair of the aortic arch and the distal aorta. Our approach for repairing the evolving dissection includes open aortic arch replacement involving all 3 supra-aortic branches in combination with the frozen elephant trunk (FET) technique (<em>n</em> = 14). Distal arch repair combines a vascular and endovascular treatment to treat aortic arch disease (<em>n</em> = 13). A 3D printed aorta model has been used preoperatively and intraoperatively to improve surgical results. Hereby we report our aortic arch surgical experience and results in the treatment for this challenging pathology.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"11 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42479665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}