Annals of 3D printed medicine最新文献

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Brain structure segmentation and 3D printed individual craniometric rulers for cortex brain lesions 脑结构分割及3D打印皮质脑损伤个体颅尺。
Annals of 3D printed medicine Pub Date : 2022-10-01 DOI: 10.1016/j.stlm.2022.100079
Dmitry N Okishev , Arevik A Abramyan , Anton N Konovalov , Yuri V Pilipenko , Elena A Okisheva , Shalva Sh Eliava , Dmitry Y Usachev
{"title":"Brain structure segmentation and 3D printed individual craniometric rulers for cortex brain lesions","authors":"Dmitry N Okishev ,&nbsp;Arevik A Abramyan ,&nbsp;Anton N Konovalov ,&nbsp;Yuri V Pilipenko ,&nbsp;Elena A Okisheva ,&nbsp;Shalva Sh Eliava ,&nbsp;Dmitry Y Usachev","doi":"10.1016/j.stlm.2022.100079","DOIUrl":"10.1016/j.stlm.2022.100079","url":null,"abstract":"<div><p>Pre-operative visualization and three-dimensional (3D) printing have gained much interest in the state-of-the-medicine. This technical note describes the technique for searching and resection of superficial cerebral cortical lesions. The method involves the creation of a patient-specific virtual model of cerebral cortex and 3D printing of an individual craniometric ruler (ICR) for skin incision marking. The benefits and limitations of ICR printing versus frameless neuronavigation are discussed. In addition, we outline the usage of surgical guides in the neurosurgical practice.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"8 ","pages":"Article 100079"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000339/pdfft?md5=6ceaf16c170eeb970e19103940d98e43&pid=1-s2.0-S2666964122000339-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44089687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of surface quality on biocompatibility of implants - A review 种植体表面质量对生物相容性的影响
Annals of 3D printed medicine Pub Date : 2022-10-01 DOI: 10.1016/j.stlm.2022.100082
Ahmad Fikri bin Anwar Fadzil , A. Pramanik , A.K. Basak , C. Prakash , S. Shankar
{"title":"Role of surface quality on biocompatibility of implants - A review","authors":"Ahmad Fikri bin Anwar Fadzil ,&nbsp;A. Pramanik ,&nbsp;A.K. Basak ,&nbsp;C. Prakash ,&nbsp;S. Shankar","doi":"10.1016/j.stlm.2022.100082","DOIUrl":"10.1016/j.stlm.2022.100082","url":null,"abstract":"<div><p>Biocompatibility is a key characteristic in the design of biomaterial such as implants. The key aspects of surface quality that affect biocompatibility are surface roughness, surface feature, surface chemistry, crystallinity and porosity. The biocompatibility can be assessed <em>in vitro</em> by observing cell behaviour such as cell differentiation, proliferation and viability. Furthermore, surface aspect such as surface roughness induced selective protein adsorption onto the biomaterial surface. The effect of surface quality on protein adsorption is also important to be understood because cells will attach to the protein adsorbed, instead of the material directly. This review paper critically analyses the role of surface quality on biocompatibility of biomaterials based on the information available in literature. For quantitative analyses, <em>in vivo</em> assessment such as osseointegration phenomenon was discussed in detail. Towards that, a systematic review was conducted with chronological development in this field.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"8 ","pages":"Article 100082"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000364/pdfft?md5=135eb048b82ecd7d8cc6a2330cab9d53&pid=1-s2.0-S2666964122000364-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47721971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Applications of 3D printing in forensic medicine and forensic pathology. A systematic review 3D打印在法医学和法医病理学中的应用。系统回顾
Annals of 3D printed medicine Pub Date : 2022-10-01 DOI: 10.1016/j.stlm.2022.100083
Gábor Simon, Viktor Soma Poór
{"title":"Applications of 3D printing in forensic medicine and forensic pathology. A systematic review","authors":"Gábor Simon,&nbsp;Viktor Soma Poór","doi":"10.1016/j.stlm.2022.100083","DOIUrl":"10.1016/j.stlm.2022.100083","url":null,"abstract":"<div><p>Three-dimensional (3D) printing became more widely available in the past decade, its medical applications are rapidly growing. The technology has also a large potential in forensic sciences – including forensic medicine and pathology. A systematic literature search was performed using electronic databases to analyze the current applications of 3D printing in forensic medicine and to reveal the possible directions of development. The first publication regarding 3D printing in the field of forensic medicine and pathology was published in 2011, but publications were scarce until 2017. Publication numbers increased in 2017 and were constant since then. The publications reveal that 3D printing can be used in everyday forensic medical practice for various purposes including injury reconstruction, injury–weapon comparison, presentation, identification and courtroom demonstration and teaching.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"8 ","pages":"Article 100083"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000376/pdfft?md5=ae4f3da8c6575eca04012d0b6e38a787&pid=1-s2.0-S2666964122000376-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46501642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
“ Initial experience with augmented reality for treatment of an orbital floor fracture – A Technical Note ” 增强现实技术治疗眶底骨折的初步经验-技术说明
Annals of 3D printed medicine Pub Date : 2022-08-01 DOI: 10.1016/j.stlm.2022.100072
Adeeb Zoabi , Daniel Oren , Shai Tejman-Yarden , Idan Redenski , Fares Kablan , Samer Srouji
{"title":"“ Initial experience with augmented reality for treatment of an orbital floor fracture – A Technical Note ”","authors":"Adeeb Zoabi ,&nbsp;Daniel Oren ,&nbsp;Shai Tejman-Yarden ,&nbsp;Idan Redenski ,&nbsp;Fares Kablan ,&nbsp;Samer Srouji","doi":"10.1016/j.stlm.2022.100072","DOIUrl":"10.1016/j.stlm.2022.100072","url":null,"abstract":"<div><p>The marked developments in the fields of 3D planning and printing in the last few decades, have enabled the application of virtual surgical planning (VSP) toward personalization of surgical procedures and implants. Augmented reality superimposes digital content on the real-world reality. The aim of this technical note was to introduce the use of AR to evaluate and guide the insertion and positioning of a patient specific implant (PSI) for orbital floor blow-out fracture reconstruction. A 31-year-old, healthy male was injured and suffered from left orbital floor blow-out fracture. DICOM images of the CT scan were obtained for segmentation and for VSP, PSI design and 3D Printing. Patients’ file with the 3D objects was uploaded to AR software. The patient's left orbital floor was approached via the trans-conjunctival incision, PSI titanium plate was set in place and using AR Special head-mounted displays (HoloLens 1, Microsoft) the correct planned position of the plate was confirmed. The post-operative CT scan showed <em>a</em> &lt;0.3 mm discrepancy in all axes of the plate in relation to the planned position. AR application in medicine and in maxillofacial surgery bears great potential, However, further investigation of this technology is required</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"7 ","pages":"Article 100072"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000261/pdfft?md5=d236cc2f91b4c95bf15115a6cd4ded59&pid=1-s2.0-S2666964122000261-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47478394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D printed orthotic leg brace with movement assist 具有运动辅助的3D打印矫形腿部支架
Annals of 3D printed medicine Pub Date : 2022-08-01 DOI: 10.1016/j.stlm.2022.100062
Maria Boolos , Sabrina Corbin , Andy Herrmann , Bradley Regez
{"title":"3D printed orthotic leg brace with movement assist","authors":"Maria Boolos ,&nbsp;Sabrina Corbin ,&nbsp;Andy Herrmann ,&nbsp;Bradley Regez","doi":"10.1016/j.stlm.2022.100062","DOIUrl":"10.1016/j.stlm.2022.100062","url":null,"abstract":"<div><p>Off the shelf, universal hinged leg braces are large, awkward looking devices that are often uncomfortable for the user. With the use of 3D printed components it is possible to modify and streamline the traditional leg brace design making it compact, lightweight, and comfortable. A customizable 3D printed orthotic leg brace is presented that provides the user with assisted mobility in addition to an increased degree of rigidity. The 3D printed frame lattice structure of the brace is tailored around the dimensions of the user's leg. The movement assist mechanism consists of dual mechatronic linear actuators mounted on the brace that aid the leg in flexion and extension during the gait cycle. The brace is a lightweight, independently functioning device that will provide increased mobility for the user.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"7 ","pages":"Article 100062"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000182/pdfft?md5=07f81e95406faa043271d86b17306af0&pid=1-s2.0-S2666964122000182-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44044762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Barriers and facilitators to the implementation of additive manufacturing in cardiology: A qualitative study 在心脏病学中实施增材制造的障碍和促进因素:一项定性研究
Annals of 3D printed medicine Pub Date : 2022-08-01 DOI: 10.1016/j.stlm.2022.100067
Anders Brantnell , Simon Sandgren , Annette Wolff , Serdar Temiz
{"title":"Barriers and facilitators to the implementation of additive manufacturing in cardiology: A qualitative study","authors":"Anders Brantnell ,&nbsp;Simon Sandgren ,&nbsp;Annette Wolff ,&nbsp;Serdar Temiz","doi":"10.1016/j.stlm.2022.100067","DOIUrl":"10.1016/j.stlm.2022.100067","url":null,"abstract":"<div><h3>Background</h3><p>Additive manufacturing (AM) is a fast-developing technology with possible applications in cardiology. Existing research has identified two general factors that can influence implementing AM in cardiology: economics and technology.</p></div><div><h3>Objective</h3><p>In this study we aimed to identify barriers and facilitators to implementing AM in cardiology.</p></div><div><h3>Methods</h3><p>We conducted a multiple case study of two Swedish cardiac surgery departments representing implementers and non-implementers of AM. We interviewed key stakeholders (n=8) who had been or were involved in implementing AM in cardiology or AM in general at the hospitals: cardiologists, physicians working with AM but not specialized in cardiology such as radiologists, company representatives, and individuals involved in the 3D-printing facilities. A combination of an inductive and deductive approach was used to analyze the interviews.</p></div><div><h3>Results</h3><p>Several barriers and facilitators influenced implementing AM in cardiology. Most barriers (n=4) were related to innovation factors, whereas most facilitators (n=4) were related to healthcare professionals. No barriers and facilitators were related to patients.</p></div><div><h3>Conclusion</h3><p>Our findings show that AM in cardiology is in its very early phases in both hospitals and mostly the work of a few individuals. In the two hospitals studied, there were some unique differences in terms of barriers that could explain the low level of implementation. These barriers could be important to address when supporting implementation of AM at hospitals where AM use is still low.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"7 ","pages":"Article 100067"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000236/pdfft?md5=59d723ad91bd3a89dbfd9de365a44219&pid=1-s2.0-S2666964122000236-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43308816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effectiveness of a conceptual three-dimensionally printed model of the middle ear in teaching complex neuroanatomy to radiology trainees 概念三维打印中耳模型在放射学学员复杂神经解剖学教学中的有效性
Annals of 3D printed medicine Pub Date : 2022-08-01 DOI: 10.1016/j.stlm.2022.100070
Cullen Fleming , Aparana Yepuri , Gaurav Watane , Anam Salman , Shivang Desai , Merissa Zeman , Ramin Javan
{"title":"Effectiveness of a conceptual three-dimensionally printed model of the middle ear in teaching complex neuroanatomy to radiology trainees","authors":"Cullen Fleming ,&nbsp;Aparana Yepuri ,&nbsp;Gaurav Watane ,&nbsp;Anam Salman ,&nbsp;Shivang Desai ,&nbsp;Merissa Zeman ,&nbsp;Ramin Javan","doi":"10.1016/j.stlm.2022.100070","DOIUrl":"10.1016/j.stlm.2022.100070","url":null,"abstract":"<div><p>Introduction Middle ear anatomy is difficult for learners because of its intricate and complex anatomy. Historically its anatomy has been taught with dissections and figures. 3D printed models have grown in popularity for their ability to represent complex structures. This study sought to assess the efficacy of a conceptual 3D printed middle ear model in radiology trainee education.</p><p>Methods An uncontrolled before-after trial was performed in which radiology trainees participated in small group teaching sessions using a 3D printed conceptual middle ear model. Participant knowledge was assessed with identical pre- and 1-week post-intervention knowledge assessments and surveys.</p><p>Results A total of 26 participants completed the study. The mean pre-intervention test score for participants (out of 20) was 6 ± 3.4, which increased to 11.7 ± 3.5 (<em>p</em>-value &lt; 0.02) following interaction with the model. Second year radiology residents had the largest improvement in score, 9.0 ± 4.2, while fourth year radiology residents had the least, 2.8 ± 2.6. The small increase in post-intervention scores for the neuroradiology fellows was not found to be statistically significant (<em>p</em>-value 0.07). Subgroup analysis of post-intervention knowledge found no statistical difference among participants of different years of training. The survey showed increased understanding and desire for incorporation into curriculum.</p><p>Discussion: Interaction with the 3D printed model was found to improve anatomical knowledge in radiology residents but not neuroradiology fellows, whose improvement was not statistically significant. All participants, regardless of their years of training, were found to have knowledge equivalent to that of a fellow following their training.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"7 ","pages":"Article 100070"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266696412200025X/pdfft?md5=829cfe1bbe7c1e213006d2c4343bda85&pid=1-s2.0-S266696412200025X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48805371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of the Anatomage Table for improving forensic odontology education and training 解剖表在提高法医牙科学教育培训中的应用
Annals of 3D printed medicine Pub Date : 2022-08-01 DOI: 10.1016/j.stlm.2022.100073
Corrado Calì , Emilio Nuzzolese
{"title":"The use of the Anatomage Table for improving forensic odontology education and training","authors":"Corrado Calì ,&nbsp;Emilio Nuzzolese","doi":"10.1016/j.stlm.2022.100073","DOIUrl":"10.1016/j.stlm.2022.100073","url":null,"abstract":"<div><p>Human and animal anatomy can benefit from the use the life-sized three-dimensional (3D) images of the Anatomage Table which is an intuitive touchscreen that allows virtual dissection, interactions, and control features, including the turning on and off of selected structures categorized on various cadaver models.</p><p>This technical note reports the innovative application of the Anatomage Table in a forensic odontology training program, allowing an accurate and high-resolution study and observation of the head, skull, jaws, and teeth, for the purpose of teaching dental autopsy procedures and standardized collection of dental autoptic parameters, as well as to familiarize with radiological images. Moreover, we propose virtual post-mortem dental data collection as an efficient tool in forensic odontology education and training, as an adjunct onsite as well as remote learning resource.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"7 ","pages":"Article 100073"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000273/pdfft?md5=1d45bc2e99aef0a837a58c8812fc7a35&pid=1-s2.0-S2666964122000273-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43372457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Patient comprehension of oncologic surgical procedures using 3D printed surgical planning prototypes 使用3D打印手术计划原型的患者对肿瘤手术程序的理解
Annals of 3D printed medicine Pub Date : 2022-08-01 DOI: 10.1016/j.stlm.2022.100068
A. Tejo-Otero , A. Valls-Esteve , F. Fenollosa-Artés , A. Siles-Hinojosa , B. Nafria , M. Ayats , I. Buj-Corral , MC. Otero , J. Rubio-Palau , J. Munuera , L. Krauel
{"title":"Patient comprehension of oncologic surgical procedures using 3D printed surgical planning prototypes","authors":"A. Tejo-Otero ,&nbsp;A. Valls-Esteve ,&nbsp;F. Fenollosa-Artés ,&nbsp;A. Siles-Hinojosa ,&nbsp;B. Nafria ,&nbsp;M. Ayats ,&nbsp;I. Buj-Corral ,&nbsp;MC. Otero ,&nbsp;J. Rubio-Palau ,&nbsp;J. Munuera ,&nbsp;L. Krauel","doi":"10.1016/j.stlm.2022.100068","DOIUrl":"https://doi.org/10.1016/j.stlm.2022.100068","url":null,"abstract":"<div><h3>Purpose</h3><p>Patient understanding of complex surgical procedures and post-intervention consequences is often poor. Little is known about the effectiveness of 3D printed models to improve the comprehension of the medical information provided to patients. The purpose of this study was to determine if 3D printed patient-specific anatomical models could help improve patients’ satisfaction and understanding of complex oncological surgical procedures, their risks, benefits, and alternatives.</p></div><div><h3>Basic procedure</h3><p>A randomized, controlled crossover experiment was performed, where subjects were randomly assigned to different treatments of the study. This experiment involved teenage patients experts from Kids Barcelona, a Young Person's Advisory Group. The team (<em>n</em> = 14, age range 14–20, 9 females and 5 males) was divided into two groups involved in two simulated pre-surgical outpatient visits for complex oncologic surgical procedures: a high-risk stage 4 abdominal neuroblastoma, and a biliary tract rhabdomyosarcoma. Two senior oncologic surgeons participated in the study by performing the structured outpatient pre-surgical visit. Each participant received information before the study explaining the study methodology and was given a questionnaire.</p></div><div><h3>Main findings</h3><p>Data analysis of the group using the 3D printed model for the neuroblastoma case showed better results than without the 3D model. On the other hand, conversely, on the data analysis of the rhabdomyosarcoma case with the 3D printed model no better results were observed as compared to the case of not using a 3D model. However, the results of the participants’ knowledge were still better than before the intervention. Satisfaction was significantly better with a 3D model in both cases.</p></div><div><h3>Conclusion</h3><p>The use of 3D physical models improves the patient's knowledge and shows the effectiveness of 3D printed models to enhance the comprehension of the medical information provided to patients and improve satisfaction.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"7 ","pages":"Article 100068"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000248/pdfft?md5=ab5bad2fe4fb84bf615d95c05f242b08&pid=1-s2.0-S2666964122000248-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137217379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Could 3D extrusion bioprinting serve to be a real alternative to organ transplantation in the future? 3D挤出生物打印将来会成为器官移植的真正替代品吗?
Annals of 3D printed medicine Pub Date : 2022-08-01 DOI: 10.1016/j.stlm.2022.100066
Kalyani Shinkar , Kawal Rhode
{"title":"Could 3D extrusion bioprinting serve to be a real alternative to organ transplantation in the future?","authors":"Kalyani Shinkar ,&nbsp;Kawal Rhode","doi":"10.1016/j.stlm.2022.100066","DOIUrl":"10.1016/j.stlm.2022.100066","url":null,"abstract":"<div><p>Additive manufacturing, or 3D printing, has made incredible steps over the last 30 years and is now being widely used for healthcare applications. There has been increasing research into the possibilities of using this technology for creating viable tissues and organs, a field known as 3D bioprinting. This is motivated by the severe mismatch in demand for organ transplantation and the availability of donors. In this review, we examine the technology of 3D bioprinting and focus on extrusion-based technology, giving its relative advantages and disadvantages. We review work on creating tissues and organs, particularly focussing on the examples of skin, liver, heart and blood vessels. We examine the challenges in creating viable tissues and organs and also the associated ethical issues. Given the great progress made already in this field, the prospect of creating fully functional tissues and organs for transplantation by 3D bioprinting is now a real near-future possibility.</p></div>","PeriodicalId":72210,"journal":{"name":"Annals of 3D printed medicine","volume":"7 ","pages":"Article 100066"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666964122000224/pdfft?md5=bee65913fbee4a47bc27a783c08fec41&pid=1-s2.0-S2666964122000224-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46188393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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