Advanced Composites and Hybrid Materials最新文献

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MX/MWCNTs composite material aids new strategy for HBV-DNA electrochemical biosensor: achieving multi-level signal amplification and unlabeled detection MX/MWCNTs复合材料有助于HBV-DNA电化学生物传感器的新策略:实现多层次信号放大和无标记检测
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-17 DOI: 10.1007/s42114-025-01215-2
Shan Huang, Huihao Li, Mingli Yang, Xinqi Liu, Yi Fang, Qi Xiao, Yue Zhang
{"title":"MX/MWCNTs composite material aids new strategy for HBV-DNA electrochemical biosensor: achieving multi-level signal amplification and unlabeled detection","authors":"Shan Huang, Huihao Li, Mingli Yang, Xinqi Liu, Yi Fang, Qi Xiao, Yue Zhang","doi":"10.1007/s42114-025-01215-2","DOIUrl":"10.1007/s42114-025-01215-2","url":null,"abstract":"","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01215-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142994877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SN2-mediated decoupled precursor provision enables large-scale production of monodisperse lead halide perovskite quantum dots in a single reactor sn2介导的去耦前驱体的提供使单分散卤化铅钙钛矿量子点在单个反应器中大规模生产成为可能
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-15 DOI: 10.1007/s42114-025-01229-w
Jigeon Kim, Woongchan Kim, Jin Il Jang, Wooyeon Kim, Doheon Yoo, Jae Woo Kim, Yubin Lee, Min-Jae Choi, Jongmin Choi, Hyung Min Kim, Sung Beom Cho, Min Jae Ko, Younghoon Kim
{"title":"SN2-mediated decoupled precursor provision enables large-scale production of monodisperse lead halide perovskite quantum dots in a single reactor","authors":"Jigeon Kim,&nbsp;Woongchan Kim,&nbsp;Jin Il Jang,&nbsp;Wooyeon Kim,&nbsp;Doheon Yoo,&nbsp;Jae Woo Kim,&nbsp;Yubin Lee,&nbsp;Min-Jae Choi,&nbsp;Jongmin Choi,&nbsp;Hyung Min Kim,&nbsp;Sung Beom Cho,&nbsp;Min Jae Ko,&nbsp;Younghoon Kim","doi":"10.1007/s42114-025-01229-w","DOIUrl":"10.1007/s42114-025-01229-w","url":null,"abstract":"<div><p>Quantum-confined lead-halide perovskite nanocrystals (QPNCs) are a promising optoelectronic semiconductor owing to their exceptional fluorescence and the size- and dimension-tunable optical properties. QPNCs having low formation energy encounter challenges in accurately regulating the nucleation and crystal growth stages during injection-based syntheses using lead halide reagents. Here, we introduce a non-injection, one-pot synthetic approach based on bimolecular nucleophilic substitution (S<sub>N</sub>2) and thermolysis reactions of the decoupled metal and halide precursors for the large-scale production of monodisperse CsPbX<sub>3</sub>-QPNCs (X = Cl, Br, I). This approach facilitates a homogeneous supply of halide anions and metal cations, enabling the precise control over the nucleation and crystal growth stages in the isolated size-focused region. Monodisperse CsPbX<sub>3</sub>-QPNCs achieve high color purity across the RGB color gamut by adjusting size, dimensionality, and halide composition, and can be produced on an ultra-large scale.\u0000</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01229-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142994406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microstructure and properties of polycrystalline diamond with AlCoCrFeNi2.1 eutectic high-entropy alloys as binder 以AlCoCrFeNi2.1共晶高熵合金为粘结剂的聚晶金刚石的组织与性能
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-14 DOI: 10.1007/s42114-025-01214-3
Wei Liu, Yue Li, Deli Gao, Yezeng He, Yasser Vasseghian, Akbar Hojjati-Najafabadi
{"title":"Microstructure and properties of polycrystalline diamond with AlCoCrFeNi2.1 eutectic high-entropy alloys as binder","authors":"Wei Liu,&nbsp;Yue Li,&nbsp;Deli Gao,&nbsp;Yezeng He,&nbsp;Yasser Vasseghian,&nbsp;Akbar Hojjati-Najafabadi","doi":"10.1007/s42114-025-01214-3","DOIUrl":"10.1007/s42114-025-01214-3","url":null,"abstract":"<div><p>The performance of polycrystalline diamond (PCD) tools largely depends on the adhesion and catalyzing effect of the binder phase. In this study, AlCoCrFeNi<sub>2.1</sub> eutectic high-entropy alloy (HEA) was used as a new binder material to synthesize the PCD samples. First-principles calculations showed that the interface strength between HEA and diamond is better than that between cobalt and diamond, suggesting that the HEA/PCD combination has the potential to exhibit better properties than the conventional cobalt/PCD tools. PCD samples with HEA as the binder phase were successfully synthesized using high-pressure and high-temperature conditions of 8.0 GPa and 1500–1700℃. Several key performance indicators, including thermal expansion coefficient, Vickers hardness, transverse rupture strength, compressive strength, and wear resistance were measured to comprehensively evaluate the overall performance of the well-sintered HEA/PCD. The results showed that, compared with conventional cobalt/PCD, the HEA/PCD exhibited a lower thermal expansion coefficient and reduced graphitization of diamond at high temperatures above 920 K. HEA/PCD also demonstrated better mechanical properties than Co/PCD, including higher hardness, and greater transverse rupture strength and compressive strength. Moreover, over the same cutting distance against the granite block, HEA/PCD tools exhibited significantly lower wear loss than Co/PCD, indicating superior wear resistance. This study provides new insights and strategies for the design and optimization of PCD binders and PCD tools.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-025-01214-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142976619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studying the wound healing property of biologically and chemically synthesized gold nanoparticles through scratch assay and neural network modeling 通过划痕实验和神经网络建模,研究生物和化学合成的金纳米颗粒的伤口愈合性能
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-14 DOI: 10.1007/s42114-024-01133-9
Anjana S. Desai, Aparna Ashok, Shivali A. Wagle, Neeru Bhagat, Zhadyra Ashirova, Zhanna T. Abdrassulova, Nurshat Abdolla, Zhazira Mukazhanova, Alibek Ydyrys, Ainur Seilkhan
{"title":"Studying the wound healing property of biologically and chemically synthesized gold nanoparticles through scratch assay and neural network modeling","authors":"Anjana S. Desai,&nbsp;Aparna Ashok,&nbsp;Shivali A. Wagle,&nbsp;Neeru Bhagat,&nbsp;Zhadyra Ashirova,&nbsp;Zhanna T. Abdrassulova,&nbsp;Nurshat Abdolla,&nbsp;Zhazira Mukazhanova,&nbsp;Alibek Ydyrys,&nbsp;Ainur Seilkhan","doi":"10.1007/s42114-024-01133-9","DOIUrl":"10.1007/s42114-024-01133-9","url":null,"abstract":"<div><p>Gold nanoparticles (Au NPs) are commonly used as anti-haemorrhagic and antiseptic agents. Thus, their cytotoxicity should be studied before application. In this study, the Au NPs were synthesized using biological and chemical routes, and the samples were named as AU-BT and AU-C, respectively. The AU-BT were synthesized using three different extracts, i.e., turmeric, aloe-vera, and a mixture of turmeric aloe-vera. The cytotoxicity was studied using scratch assay on HEK-293 cell lines. The number of scratch assays was increased to validate the experimental wound healing results. Finally, a neural networking modeling was performed to predict the results of provided data in terms of the sample toxicity by healing the wound. The experimental results and the neural networking confirmed that the turmeric-derived Au NPs were the best among all the synthesized samples. Moreover, integrating metal NPs in wound healing studies introduces exciting possibilities for enhanced imaging and therapeutic interventions. The combination of advanced image analysis through models like AlexNet and the novel use of nanoparticles opens doors to improved wound care and a deeper understanding of the healing process.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142976517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymer matrix composites from high-temperature cyanate ester resins and boron nitride nanotube-seeded electrospun fibers 高温氰酸酯树脂和氮化硼纳米管静电纺纤维聚合物基复合材料
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-14 DOI: 10.1007/s42114-024-01189-7
Joseph E. Estevez, Michael D. Garrison, S. A. Razgaleh, Benjamin G. Harvey, Troy Ansell, Christopher G. Yelton, Gretchen H. Hefley
{"title":"Polymer matrix composites from high-temperature cyanate ester resins and boron nitride nanotube-seeded electrospun fibers","authors":"Joseph E. Estevez,&nbsp;Michael D. Garrison,&nbsp;S. A. Razgaleh,&nbsp;Benjamin G. Harvey,&nbsp;Troy Ansell,&nbsp;Christopher G. Yelton,&nbsp;Gretchen H. Hefley","doi":"10.1007/s42114-024-01189-7","DOIUrl":"10.1007/s42114-024-01189-7","url":null,"abstract":"<div><p>Boron nitride nanotubes (BNNTs) have great potential as reinforcing agents in polymer composites due to their robust mechanical and thermal properties. BNNT-Polyacrylonitrile (PAN) electrospun composite nanofibers were fabricated with BNNT loadings ranging from 5 to 20 weight percent (wt%) using a high-shearing mixing process. The resulting fibers were then converted to hybrid BN carbon fiber via a stabilization and carbonization process without the addition of strain. The converted fibers exhibited interfacial bonding between the converted carbon matrix and BNNTs, without the need for surface activation or functionalization. At 20 wt% BNNT loading, the hybrid BNNT carbon fiber demonstrated a cohesive network of BNNTs throughout the fiber core, providing a high level of interconnectivity and an additional load-bearing structure. This was evident by the increase in tensile strength and storage modulus for the 20 wt% hybrid BNNT carbon fiber compared to the carbon fiber without BNNTs. Furthermore, we infused the electrospun carbon fiber with a cyanate ester resin to investigate the interface between the enhanced BNNT-seeded carbon fiber and the carbon fiber without BNNTs. Results show that incorporation of the cyanate resin improved the ductility of the brittle carbon electrospun fibers, reducing their tendency to fracture. The composites exhibited similar trends in mechanical strength to the fibers without the matrix, confirming a good interface between the fibers and the matrix. These findings demonstrate the potential of BNNTs as a high-performance reinforcing agent in polymer composites and provide insights into the design and fabrication of a hybrid BN carbon fiber.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142976620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Grain gradient refinement and corrosion mechanisms in metals through severe plastic deformation: insights from Surface Mechanical Attrition Treatment (SMAT) 通过严重塑性变形的金属晶粒梯度细化和腐蚀机制:来自表面机械磨损处理(SMAT)的见解
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-14 DOI: 10.1007/s42114-024-01167-z
Xiwen Yue, Huayun Du, Lingqi Zhang, Lifeng Hou, Qian Wang, Huan Wei, Xiaoda Liu, Yinghui Wei
{"title":"Grain gradient refinement and corrosion mechanisms in metals through severe plastic deformation: insights from Surface Mechanical Attrition Treatment (SMAT)","authors":"Xiwen Yue,&nbsp;Huayun Du,&nbsp;Lingqi Zhang,&nbsp;Lifeng Hou,&nbsp;Qian Wang,&nbsp;Huan Wei,&nbsp;Xiaoda Liu,&nbsp;Yinghui Wei","doi":"10.1007/s42114-024-01167-z","DOIUrl":"10.1007/s42114-024-01167-z","url":null,"abstract":"<div><p>Surface Mechanical Attrition Treatment (SMAT) is an efficient surface nano-crystallization technique that significantly enhances the corrosion resistance of various metallic materials by refining grain structure and introducing residual compressive stress. This paper provides a comprehensive review of the application of SMAT on metals, including stainless steel, magnesium alloys, and titanium alloys, focusing on its mechanisms in mitigating pitting corrosion, stress corrosion cracking, and general corrosion. The review begins by examining the effects of SMAT on residual stress, grain refinement, and surface condition modifications, followed by proposing optimization strategies for the treatment process. Through a combination of electrochemical testing, microstructural characterization, and numerical simulations, the paper highlights the pivotal role of residual compressive stress and the nanocrystalline layer in the formation of passive films and the evolution of surface oxide layers, particularly under various corrosive environments. Additionally, the paper presents a comparative analysis of corrosion mechanisms in different metals post-SMAT treatment. The treatment can also induce phase transformations, such as martensitic transformation and the formation of metastable phases, which have significant implications for corrosion behavior. Finally, the synergistic effects of SMAT when combined with other surface treatment techniques, such as micro-arc oxidation and ion implantation, are discussed, along with an evaluation of its feasibility and limitations for industrial applications. By comparing the performance and cost-effectiveness of SMAT with other techniques, this paper provides valuable insights and a solid technical foundation for the optimization of metallic materials in highly corrosive environments, such as aerospace and marine engineering.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142976516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carboxymethyl cellulose sodium/bentonite composite adsorbent for Cd(II) adsorption from wastewater 羧甲基纤维素钠/膨润土复合吸附剂对废水中镉的吸附
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-11 DOI: 10.1007/s42114-024-01185-x
Wang Li, Lianzheng Zhang, Tongming Su, Xuan Luo, Xinling Xie, Zuzeng Qin
{"title":"Carboxymethyl cellulose sodium/bentonite composite adsorbent for Cd(II) adsorption from wastewater","authors":"Wang Li,&nbsp;Lianzheng Zhang,&nbsp;Tongming Su,&nbsp;Xuan Luo,&nbsp;Xinling Xie,&nbsp;Zuzeng Qin","doi":"10.1007/s42114-024-01185-x","DOIUrl":"10.1007/s42114-024-01185-x","url":null,"abstract":"<div><p>Severely polluting wastewater containing heavy metal ions has become a pressing issue. To address the current shortcomings of natural bentonite (Bent) and carboxymethyl cellulose sodium (CMC) for Cd(II) adsorption, this study developed a cellulose/bentonite composite adsorbent (CMC<sub>MW</sub>-Bent) via microwave-assisted synthesis using acrylic acid (AA)-modified CMC and pretreated bentonite (Bent), and the adsorbent was used to remove Cd(II) from wastewater. The results show that the strong interaction between AA and CMC, which successfully entered the bentonite layer, and the bentonite provided excellent structural stability and abundant adsorption sites for the adsorption process. Meanwhile, microwave-assisted heating enhanced this unique structure compared to traditional heating with the aqueous solution. The best adsorption effect occurred at pH = 6–7, with a maximum adsorption capacity of 44.76 mg/g for Cd(II). The isothermal adsorption and kinetic models demonstrate that the adsorption process followed the Langmuir adsorption fitting and pseudo-second-order kinetic equations. The thermodynamic study confirms that the adsorption process was a spontaneous endothermic process and a chemical adsorption process. This study provides a new approach for obtaining efficient adsorbents.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-024-01185-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A p-type thermoelectric fabric power supply device 一种p型热电织物供电装置制造方法及图纸
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-11 DOI: 10.1007/s42114-024-01182-0
Feichong Yao, Wenhao Xie, Xiqiu Zhao, Hongbo Gu
{"title":"A p-type thermoelectric fabric power supply device","authors":"Feichong Yao,&nbsp;Wenhao Xie,&nbsp;Xiqiu Zhao,&nbsp;Hongbo Gu","doi":"10.1007/s42114-024-01182-0","DOIUrl":"10.1007/s42114-024-01182-0","url":null,"abstract":"<div><p>With the advent of the information age, wearable thermoelectric fabric devices have garnered significant attention for their ability to harness environmental waste heat and body heat to supply convenient, reliable, and environmentally friendly electricity for next-generation wearable electronics. However, the complex production process and unstable power supply restrict their development. Here, we report a high-performance flexible, dependable, and wearable p-type thermoelectric device consisting of silk threads/polyaniline/amino multiwalled carbon nanotubes through dyeing process. By optimizing the weaving structure and simple assembly, this p-type fabric device generates a voltage of 0.749 ± 0.003 mV, a maximum power of 0.326 ± 0.007 nW, and a power density of 1087.532 ± 22.985 nW·m<sup>−2</sup> at a temperature difference of 90 ℃. Besides, this device also possesses an excellent photo-thermoelectric conversion capability and the assembled fabric bracelet can generate an output voltage of approximately 6.1 mV outdoors when worn on the hand of the experimental personnel. This fabric device also exhibits a superb reliable property even after 5000 times of folding. This strategy makes it easy to manufacture a thermoelectric fabric device on a large scale and provides a promising way for wearable electronics.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142940957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifunctional composite capsules in drug delivery systems: bridging pharmaceutical and biomedical applications 药物输送系统中的多功能复合胶囊:连接制药和生物医学应用
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-11 DOI: 10.1007/s42114-024-01203-y
Qing Yu, Zhixiang Tian, Guanyan Li, Yafeng Yang, Xiangmeng Chen, Dong Wang, Wanxi Peng, Runqiang Liu, Haiping Gu, Xiaochen Yue
{"title":"Multifunctional composite capsules in drug delivery systems: bridging pharmaceutical and biomedical applications","authors":"Qing Yu,&nbsp;Zhixiang Tian,&nbsp;Guanyan Li,&nbsp;Yafeng Yang,&nbsp;Xiangmeng Chen,&nbsp;Dong Wang,&nbsp;Wanxi Peng,&nbsp;Runqiang Liu,&nbsp;Haiping Gu,&nbsp;Xiaochen Yue","doi":"10.1007/s42114-024-01203-y","DOIUrl":"10.1007/s42114-024-01203-y","url":null,"abstract":"<div><p>Chronic diseases such as cancer and diabetes demand advanced drug delivery methods that can accommodate precise, sustained, and targeted release of active compounds. Existing drug carriers such as conventional capsules are limited by issues like poor bioavailability, mechanical fragility, and unpredictable release patterns. With the global drug delivery market expected to surpass USD 1.8 trillion by 2028, it is crucial to address these challenges. Additionally, there is a growing need to develop biocompatible systems that can mitigate concerns about toxicity, environmental impact, and patient compliance. Here, we review the latest advancements in composite drug capsules, focusing on key aspects such as controlled drug release, mechanical properties, biocompatibility, and antimicrobial potential. Composite materials offer customised release mechanisms by combining synthetic and natural polymers. This has led to improvements in stability, encapsulation efficiency, and bioavailability. Some noteworthy advancements in this field include the development of magnetic-responsive systems for targeted therapies, alginate-based dual-release systems, and solid lipid nanoparticles (SLNs) for gene delivery. For example, the encapsulation of lycopene in whey protein composites achieved an impressive encapsulation efficiency of 94%, showcasing enhanced delivery performance. Additionally, there have been developments in pH-sensitive capsules designed for cancer treatment, which release drugs selectively in tumour environments. Furthermore, multifunctional magnetic capsules have been created to facilitate MRI imaging and remote-controlled drug release. Moreover, pH-sensitive alginate-based capsules have proven effective in improving the therapeutic outcomes of cancer treatments by ensuring drug release specifically within the acidic tumour microenvironment. Other notable achievements include the integration of antioxidant nanoparticles, such as cerium oxide (CeO₂), into drug delivery systems, showing potential for mitigating oxidative stress and providing neuroprotection in inflammatory and neurodegenerative conditions. Despite these innovations, persistent challenges related to scalability, regulatory clearance, and enduring biocompatibility necessitate further investigation. These combined capsules possess significant potential, presenting more intelligent, adaptable drug delivery systems positioned to transform personalised medicine and future healthcare solutions.</p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s42114-024-01203-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In situ growth of three-dimensional walnut-like nanostructures of W-Ni2P@NiFe LDH/NF as efficient bifunctional electrocatalysts for water decomposition 原位生长三维核桃状纳米结构W-Ni2P@NiFe LDH/NF作为水分解的高效双功能电催化剂
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2025-01-10 DOI: 10.1007/s42114-024-01176-y
Yu Gao, Xin Sun, Gaber A. M. Mersal, A. Alhadhrami, Mohamed M. Ibrahim, Yulong Hou, Wenhui Liu, Denise Bildan, Hassan Algadi, Terence X. Liu
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