Alpha psychiatry最新文献

{"title":"Subjective Cognitive Decline and Quality of Life During Aging: A Thin Line Between Healthy and Pathological?","authors":"Sergio Machado, João Lucas Lima, Daianne Papini, Alberto Souza de Sá Filho","doi":"10.5152/alphapsychiatry.2023.010323","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.010323","url":null,"abstract":"Subjective cognitive decline is defined as a self-perception of cognitive decline, without an objectively measurable impairment on neuropsychological tests. 1,2 Subjective refers to the individual’s self-experience as opposed to impairment in neuropsychological tests. Cognitive rather than memory because early symptoms may not be limited to amnestics alone. And finally, decline alludes to the idea of progressive deterioration and not just an isolated and static complaint. It is estimated that the elderly population, which remains cognitively nor-mal and preserves its autonomy and functional independence, 3,4 will rise from 57.4 in 2019 to 152.8 million cases in 2050. 5","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b4/d0/ap-24-2-65.PMC10151954.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9407706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Suicide CARE\" Is Proactively Required to Reduce the Suicide Death Rate in the Identified Hotspots in South Korea.","authors":"Seon-Cheol Park","doi":"10.5152/alphapsychiatry.2023.020323","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.020323","url":null,"abstract":"Lee et al1 have reported remarkable findings on the spatiotemporal patterns of suicides in South Korea from 2009 to 2019. Here, the age-adjusted suicide rate per 100 000 people has gradually and continuously decreased from 29.1 to 22.0. Using the geographic information system, among the 229 regions, 27 hotspots were identified or detected from emerging hotspot analyses of the age-standardized suicide rate in South Korea. In addition, the 27 hotspots were divided into 2 new spots: 1 persistent spot, 23 sporadic spots, and 1 oscillating spot. However, the reason why the 27 hotspots were identified in South Korea over 11 years has not been thoroughly explained. Moreover, the sociocultural factors that contributed to the identification or detection of these hotspots were not explained. Despite these limitations, the findings suggest that these regions are potentially important management areas for reducing suicide rates from the viewpoint of public mental health policy in South Korea.","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4c/6c/ap-24-2-56.PMC10151938.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9415133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life in People With Subjective Cognitive Decline.","authors":"Alexandru Pavel,&nbsp;Radu Paun,&nbsp;Valentin Matei,&nbsp;Alina Rosca,&nbsp;Catalina Tudose","doi":"10.5152/alphapsychiatry.2023.221007","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.221007","url":null,"abstract":"<p><strong>Objective: </strong>Quality of life is extensively studied in older persons, but there are few studies that investigate it in people with subjective cognitive decline. Our aim was to evaluate the quality of life in a Romanian sample of individuals with subjective cognitive decline compared to controls while accounting for different possible moderators. To our knowledge, this is the first study to evaluate the quality of life in a Romanian subjective cognitive decline sample.</p><p><strong>Methods: </strong>We conducted an observational study to evaluate differences in the quality of life between subjective cognitive decline and controls. Participants were evaluated for subjective cognitive decline according to Jessen et al. We collected sociodemographic and clinical characteristics and information about physical activity. Quality of life was evaluated using the Short Form-36 questionnaire.</p><p><strong>Results: </strong>There were 101 participants included in the analysis with 66.33% (n = 67) in the subjective cognitive decline group. There were no differences between the social, demographic, and clinical characteristics of the individuals. The subjective cognitive decline group had a higher score on the negative emotion trait of Big Five. Individuals with subjective cognitive decline reported poorer physical functioning (<i>P</i> = .034), more role limitations due to physical health (<i>P</i> = .010) and emotional problems (<i>P</i> = .019), and less energy (<i>P</i> = .018) compared to the control group.</p><p><strong>Conclusion: </strong>Persons with subjective cognitive decline reported diminished quality of life compared to controls and differences were not explained by other sociodemographic and clinical characteristics evaluated. This area could prove to be an important target for nonpharmacological interventions in the subjective cognitive decline group.</p>","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/26/ap-24-2-60.PMC10151925.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9421009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Role of Affective Temperamental Features, Automatic Thoughts, and Symptom Interpretation on Disease Activity in Patients with Axial Spondyloarthritis.","authors":"Tuğba İzci Duran,&nbsp;Melih Pamukçu,&nbsp;Hasan Ulusoy,&nbsp;Kürşat Altınbaş","doi":"10.5152/alphapsychiatry.2023.22908","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.22908","url":null,"abstract":"<p><strong>Objective: </strong>Axial spondyloarthritis is a systemic and chronic inflammatory disease. Psychological liability to depression and anxiety influences the disease process, prognosis, and treatment outcomes of other medical conditions. Early detection and treatment of these psychiatric conditions would also help in improving the physical functioning of patients with axial spondyloarthritis by reducing the patient's anxiety and depression symptoms. We evaluated the affective temperamental features, automatic thoughts, symptom interpretation, and their relationship with disease activity in patients with axial spondyloarthritis.</p><p><strong>Methods: </strong>A total of 152 patients diagnosed with axial spondyloarthritis are recruited. Axial spondyloarthritis disease activity was calculated by Bath Ankylosing Spondylitis Disease Activity Index. Depression and anxiety levels were screened with Hospital Anxiety and Depression Scale while affective temperament was evaluated with Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-autoquestionnaire version and automatic thoughts were screened with Symptom Interpretation Questionnaire, and Automatic thoughts questionnaire.</p><p><strong>Results: </strong>It was observed that 48% (n = 73) were female. The mean age was 43.5 (10.5) years, Bath Ankylosing Spondylitis Disease Activity Index score was 3.97 (1.14). According to the Bath Ankylosing Spondylitis Disease Activity Index scale, 53.30% (n = 81) of the patients were in high disease activity. We found that HAD-depression, HAD-anxiety, Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-autoquestionnaire version, Symptom Interpretation Questionnaire, and Automatic Thoughts Questionnaire scores were significantly higher in the high disease activity group.</p><p><strong>Conclusion: </strong>Patients' temperament characteristics and mood disorders may affect composite disease activity scores such as Bath Ankylosing Spondylitis Disease Activity Index. In patients with high disease activity scores despite receiving appropriate treatment, mood disorders may need to be evaluated. There is a need to develop disease activity scores unaffected by mood disorders.</p>","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/79/98/ap-24-2-68.PMC10152049.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9407707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do Children with Attention Deficit and Hyperactivity Disorder Present with Different Spatio-Temporal Gait Parameters? An Evaluation of the Relationship Between Gait and Gross Motor Skills.","authors":"Arzu Demircioğlu,&nbsp;Songül Atasavun Uysal,&nbsp;Buse Büşra Şanlı Dumankaya,&nbsp;Elif Kırdı,&nbsp;Halime Tuna Çak Esen,&nbsp;Osman Dağ,&nbsp;Semra Topuz","doi":"10.5152/alphapsychiatry.2023.22976","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.22976","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the current study was to compare the spatio-temporal parameters of gait and gross motor skills in children with attention deficit hyperactivity disorder-combined type with those of typically developing children and to search the effect of motor skills on gait parameters in children with attention deficit hyperactivity disorder-combined type.</p><p><strong>Methods: </strong>A total of 50 children (n = 25 attention deficit hyperactivity disorder-combined type, n = 25 typically developing children) aged 5-12 years were included. Gross motor skills were evaluated using the Bruininks-Oseretsky Test Second Edition-Short Form. Spatio-temporal parameters of gait were assessed with a GAITRite^® computer-based system.</p><p><strong>Results: </strong>In the subtests of Bruininks-Oseretsky Test Second Edition-Short Form (bilateral coordination (<i>P</i> < .001), balance (<i>P</i> = .013), running speed and agility (<i>P</i> = .003)), lower scores were obtained by the children with attention deficit hyperactivity disorder-combined type. The swing phase of gait was found to be longer in children with attention deficit hyperactivity disorder-combined type (<i>P</i> = .01).</p><p><strong>Conclusion: </strong>The current study results show that gross motor skills are affected negatively and the swing phase is prolonged in children with attention deficit hyperactivity disorder-combined type. Upper limb coordination and balance were also seen to have an effect on the velocity, step, and stride length. It is important to include an objective gait assessment as well as gross motor skills in the comprehensive clinical evaluation of children with attention deficit hyperactivity disorder-combined type.</p>","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a1/db/ap-24-1-1.PMC9985067.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10849536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Emotional Dysregulation, Alexithymia and Somatization in Patients with Bipolar Disorder.","authors":"Batuhan Ayık,&nbsp;Alper Baş,&nbsp;Nazife Gamze Usta Sağlam,&nbsp;Filiz İzci","doi":"10.5152/alphapsychiatry.2023.22974","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.22974","url":null,"abstract":"<p><strong>Objective: </strong>Emotional dysregulation is a basic feature found in patients with bipolar disorder. It was also reported that higher alexithymia scores are a predictive factor for a decrease in social functionality. It is known that patients with bipolar disorder experience more somatic symptoms than the general population. No study has yet been conducted on the interrelation of these 3 clinical domains, which are known to negatively affect the functionality and quality of life in bipolar disorder patients.</p><p><strong>Methods: </strong>This study included 72 bipolar disorder-1 patients. The Difficulties in Emotion Regulation Scale was used to determine the emotional state of the patients, the Toronto Alexithymia Scale was used to determine the alexithymia scores, and the Somatization Scale was used to determine the somatization scores.</p><p><strong>Results: </strong>As a result of hierarchical multiple linear regression analysis, the first model was found to be significant (<i>P</i> < .001), and the emotional dysregulation total scale score significantly predicted the Toronto Alexithymia Scale total scale score (<i>P</i> < .001). The second model was also found to be significant (<i>P</i> < .001), and the emotional dysregulation total scale score significantly predicted the somatization total scale score (<i>P</i> < .001).</p><p><strong>Conclusion: </strong>This study found that ED predicted alexithymia and somatization in euthymic bipolar patients. The therapeutic approaches targeting these 3 clinical domains that negatively affect patients' quality of life and functionality may provide positive clinical outcomes.</p>","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e1/05/ap-24-1-15.PMC9985064.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10857235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lithium-Induced Cutaneous Pseudolymphoma.","authors":"Yunna Lee","doi":"10.5152/alphapsychiatry.2023.221037","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.221037","url":null,"abstract":"Lithium, an effective drug for mood disorders, may cause kidneyand thyroid-related adverse reactions.1 A meta-analysis reported that the association between lithium and skin disorders was not significant.2 However, cases of acne, psoriasis, and rash have been reported.3 Herein, I report a lithium-induced cutaneous pseudolymphoma case in a patient with no previous cutaneous disease. Ethical committee approval was obtained from the Institutional Review Board of Kosin University Gospel Hospital in South Korea (approval number: KUGH 2022-10-020).","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e1/23/ap-24-1-34.PMC9985103.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10857238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary: Is Torasemide a Potential Agent in the Treatment of Autism?","authors":"Sergio Machado,&nbsp;João Lucas Lima,&nbsp;Claudio Imperatori,&nbsp;Alberto Souza de Sá Filho","doi":"10.5152/alphapsychiatry.2023.27122022","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.27122022","url":null,"abstract":"So far, there is no specific and effective drug for the treatment of autism symptoms, just to comorbidities associated with ASD.2 A few years ago, some studies investigated the effects of a specific drug, called bumetanide on autism symptoms in children and adults.3-5 Bumetanide is an inhibitor of the Na+–K+–2Cl− cotransporter 1 (NKCC1) that plays essential roles in GABA receptors.6 Evidence has shown that dysfunction in the GABAergic signaling pathway is significantly associated with the main symptoms of ASD.7","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/6e/ap-24-1-32.PMC9985063.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9831212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the Turkish Version of the Dark Future Scale.","authors":"İbrahim Yakın,&nbsp;Esin Temeloğlu Şen","doi":"10.5152/alphapsychiatry.2023.22972","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.22972","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the psychometric properties of the Turkish version of the Dark Future Scale that measures future anxiety.</p><p><strong>Methods: </strong>The sample consisted of 478 university students aged 18-25 and used convenience sampling. They completed an online survey about sociodemographics, tobacco use, and life satisfaction, Dark Future Scale and Trait Anxiety Inventory-2 Trait Scale. Confirmatory factor analysis and Cronbach alpha values were used to test scale's structural validity and reliability. For convergent validity, we correlated the Turkish version of the Dark Future Scale with trait anxiety and examined the mean differences in smoking status and its association with life satisfaction.</p><p><strong>Results: </strong>Majority of the participants were female (73.6%), with a mean age of 21.5 (SD = 1.67). Majority (53.6%) were regular tobacco users. Results of the confirmatory factor analysis revealed a 1-factor solution to be most optimal (<i>χ</i> ² = 17.091, df = 4, <i>P</i> = .002, χ²/df = 4.3, and root-mean-square error = 0.083, comparative fit index = 0.988, general fit index = 0.986, The Adjusted Goodness of Fit (AGFI) = 0.986, normalized fit index = 0.985). The alpha value for the scale reliability was 0.86. Turkish version of the Dark Future Scale was also significantly and positively correlated with trait anxiety (<i>r</i>(478) = .67, <i>P</i> <.01). Exploration of the association between smoking status and Turkish version of the Dark Future Scale showed that the mean score was significantly higher among smokers (M = 19.1, SD = 6.65) than nonsmokers (M = 17.7, SD = 7.69). Lastly, higher future anxiety was associated with lower life satisfaction (<i>r</i>(478) = -0.42, <i>P</i> < .01).</p><p><strong>Conclusion: </strong>Turkish version of the Dark Future Scale is a reliable and valid scale to measure future anxiety. A brief and easy to apply, reliable, and valid future anxiety measure may be useful for many researchers in psychology and psychiatry.</p>","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/34/ap-24-1-8.PMC9984914.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10849535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Torasemide Improves the Propionic Acid-Induced Autism in Rats: A Histopathological and Imaging Study.","authors":"Murat Doğan,&nbsp;Yakup Albayrak,&nbsp;Oytun Erbaş","doi":"10.5152/alphapsychiatry.2023.22975","DOIUrl":"https://doi.org/10.5152/alphapsychiatry.2023.22975","url":null,"abstract":"<p><strong>Objective: </strong>Autism spectrum disorder is a neurodevelopmental disease in which impaired social behaviors, impaired sociality, and restricted and repetitive behaviors are seen. Bumetanide is a loop diuretic that inhibits Na⁺-K⁺-2Cl^- cotransporter 1 and it is currently used in clinical phase studies in patients with autism spectrum disorder. In present research, it is purposed to demonstrate the beneficial effects of torasemide which is another Na⁺-K⁺-2Cl^- cotransporter 1 inhibitor on an experimental autism model induced with propionic acid by providing imaging and brain tissue investigations.</p><p><strong>Methods: </strong>Male Wistar rats were used in the present study (n = 30). Propionic acid of 250 mg/kg/day was administrated intraperitoneally in rats to induce autism for 5 days. Three groups were created for present study as follows: group 1, normal control (n = 10); group 2, propionic acid and saline given group (n = 10); group 3, propionic acid + tora-semide-administrated group (n = 10).</p><p><strong>Results: </strong>Torasemide group scored higher on behavioral tests compared to saline group. The brain levels of malondialdehyde, tumor necrosis factor-alpha, interleukin-2, interleukin-17, and Nuclear Factor kappa B (NF-κB), Glial fibrillary acidic protein (GFAP) were remarkably higher in propionic acid + saline group. In histopathology assessments, torasemide group had higher neuronal count of Cornu Ammonis 1, neuronal count of Cornu Ammonis 2 in hippocampus, and Purkinje cells in cerebellum. GFAP immunostaining index (Cornu Ammonis 1) and cerebellum were lower in torasemide group. Magnetic resonance spectroscopy revealed that mean lactate value was higher in propionic acid + saline group compared to torasemide group.</p><p><strong>Conclusion: </strong>Our experimental results showed that torasemide might enhance gamma-aminobutyric acid activity. Torasemide can be considered another promising Na⁺-K⁺-2Cl^- cotransporter 1 inhibitor in the treatment of autism with a longer half-life and less side effects after further studies.</p>","PeriodicalId":72151,"journal":{"name":"Alpha psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a5/5d/ap-24-1-22.PMC9984905.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10850001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}