Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii最新文献_第2页

Rare skin tumours in organ transplant recipients 器官移植受者罕见的皮肤肿瘤

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2020-01-01 DOI: 10.5114/ADA.2020.102100

B. Imko‐Walczuk, Joanna Renczyńska-Matysko, D. Kadylak, A. Dębska-Ślizień

引用次数: 0

Mutation in the KRT1 gene causing epidermolysis bullosa simplex KRT1基因突变引起单纯大疱性表皮松解症

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2020-01-01 DOI: 10.5114/ada.2020.93443

Katarzyna Osipowicz, K. Wertheim-Tysarowska, E. Jankowska, M. Gos, A. Charzewska, K. Woźniak, C. Kowalewski

引用次数: 0

The B7 family molecules in oral squamous cell carcinoma: a systematic review. Part II: B7-1, B7-2, B7-H2, B7-H3, B7-H4, B7-H5 (VISTA), B7-H6 and B7-H7 B7家族分子在口腔鳞状细胞癌中的作用:系统综述。第二部分:B7-1、B7-2、B7-H2、B7-H3、B7-H4、B7-H5 (VISTA)、B7-H6和B7-H7

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2020-01-01 DOI: 10.5114/ada.2020.98523

A. Starzyńska, A. Sejda, Ł. Adamski, P. Adamska, R. Pęksa, M. Sakowicz-Burkiewicz, P. Wychowański, B. Jereczek-Fossa

{"title":"The B7 family molecules in oral squamous cell carcinoma: a systematic review. Part II: B7-1, B7-2, B7-H2, B7-H3, B7-H4, B7-H5 (VISTA), B7-H6 and B7-H7","authors":"A. Starzyńska, A. Sejda, Ł. Adamski, P. Adamska, R. Pęksa, M. Sakowicz-Burkiewicz, P. Wychowański, B. Jereczek-Fossa","doi":"10.5114/ada.2020.98523","DOIUrl":"https://doi.org/10.5114/ada.2020.98523","url":null,"abstract":"Introduction: The most common malignant neoplasm of the oral cavity is squamous cell carcinoma. It accounts for over 95% of malignant lesions in this area and is characterised by rapid spread and distant metastases. Aim: To collect and review the data on B7 family proteins as prognostic factors in oral squamous cell carcinoma and to describe their role in aggressive disease progression. Material and methods: A systematic review of the literature about B7-1, B7-2, B7-H2, B7-H3, B7-H4, B7-H5 (VISTA), B7-H6 and B7-H7, was carried out, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. 9 articles published before 22 May 2020 were included in the systematic review. Results: The biggest study group consisted of 201 patients and the smallest – 40 patients. B7-1, B7-H3, B7-H4, B7-H5, B7-H6 and B7-H7 protein expressions were prognostic factors. Overall survival was significantly associated with B7-H3, B7-H5, B7-H6 and B7-H7. Immunohistochemistry was the diagnostic method used in all the studies. Conclusions: The data presented indicate the complexity of cellular and molecular processes related to the forma-tion, development and invasion of oral cancer. Mutations in genes encoding the B7 family and changes in the B7 protein pathway may affect the prognosis of survival in patients with oral squamous cell carcinoma. -1722C/T, -1661A/G, -1661G/G, -1661A/A and -318C/T the promoter region, 49A/G in exon 1, and CT60A/G in the 3’untrans-lated Genotypes:","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88801412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Relationship between quality of life and anxiety aspects in chronic spontaneous urticaria 慢性自发性荨麻疹患者生活质量与焦虑的关系

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2019-01-01 DOI: 10.5114/ADA.2019.85811

A. Oles-Krykowska, K. Badura-Brzoza, Z. Brzoza

{"title":"Relationship between quality of life and anxiety aspects in chronic spontaneous urticaria","authors":"A. Oles-Krykowska, K. Badura-Brzoza, Z. Brzoza","doi":"10.5114/ADA.2019.85811","DOIUrl":"https://doi.org/10.5114/ADA.2019.85811","url":null,"abstract":"Abst rac t Introduction: Clinical experience indicates the role of the psychological component in chronic spontaneous urticaria (CSU). The CSU can lead to psychological disturbances. This phenomenon results in a possible quality of life impairment among CSU patients. Aim: To analyse in detail the quality of life parameters and anxiety aspects in relation to CSU duration and symptom intensity. Material and methods: The patient sample was composed of 67 CSU subjects. For the quality of life and mental status assessment, all subjects were questionnaired with CU-Q 2oL and State and Trait Anxiety Inventory (STAI). In the control group, 42 healthy volunteers were enrolled to fill in the STAI questionnaire. The Urticaria Activity Score (UAS) was used to assess disease activity. Results: We observed greater intensity of anxiety as a state and as a trait in CSU patients and greater intensity of anxiety as a state due to increasing patients’ age. The CU-Q 2oL Itching subscale was significantly impaired as a result of the intensity of the UAS scale. The Swelling/Mental status subscale was related to anxiety as a state and as a trait. Additionally, we noticed a greater quality of life impairment in subjects with longer disease duration. Conclusions: Our results prove that CSU results in a significant quality of life impairment. This phenomenon particularly concerns patients with longer disease duration time. As anxiety is a relatively frequent disturbance and negatively influences quality of life, we should identify these patients and monitor this parameter especially in older patients.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77303984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Behçet’s syndrome and relationship with the ratio of insulin-like growth factor-1 (IGF-1)/IGF-binding protein-3 (IGFBP-3) behet综合征及其与胰岛素样生长因子-1 (IGF-1)/ igf结合蛋白-3 (IGFBP-3)比值的关系

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2019-01-01 DOI: 10.5114/ADA.2019.85640

Özlem Doğan, Emine Ünal, U. Kisa, Nurkan Aksoy

{"title":"Behçet’s syndrome and relationship with the ratio of insulin-like growth factor-1 (IGF-1)/IGF-binding protein-3 (IGFBP-3)","authors":"Özlem Doğan, Emine Ünal, U. Kisa, Nurkan Aksoy","doi":"10.5114/ADA.2019.85640","DOIUrl":"https://doi.org/10.5114/ADA.2019.85640","url":null,"abstract":"Abst rac t Introduction: Behçet’s syndrome (BS) is a chronic inflammatory disease with unknown aetiology. Insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) have important metabolic properties such as anabolic, cytoprotective and anti-inflammatory effects. Circulating IGF-1 and IGF-1/IGFBP-3 concentrations are associated with adiposity and insulin resistance. Aim: To determine whether serum IGF-1 and IGFBP-3 levels or IGF-1/IGFBP-3 ratio were associated with the presence or activity of BS. Material and methods: Forty patients with BS (mean age: 39.6 ±10), and 20 healthy volunteers (mean age: 37 ±10.4) were enrolled. Serum IGF-1, IGFBP-3, and high sensitive C-reactive protein (hs-CRP) and erythrocyte sedimentation rate (ESR) levels were measured in all subjects. Results: Mean IGF-1 levels were low in both active BS and remission BS compared to the control group and mean IGF-1 levels were similar in active BS and remission BS. In active BS, mean IGFBP-3 levels were higher than in the control group and remission BS. There were positive correlations between these inflammatory cytokines and IGFBP-3 levels. IGF-1/IGFBP-3 ratio was lower in patients with BS compared to the healthy volunteer group, which was statistically significant. IGF-1/IGFBP-3 ratio was lower in BS than in the control group independently of ESR and hs-CRP. Conclusions: IGF-1 may play a diagnostic role to present itself in BS. IGF-1/IGFBP-3 ratio is not useful as an activation or remission criterion. The ratio may be a useful marker to predict the risk of BS presence in the critical population.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89136998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin allergic reaction to SCS – analysis of world literature and case report 皮肤对SCS的过敏反应——世界文献分析及病例报告

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2018-01-01 DOI: 10.5114/ADA.2018.78781

Kamila Woźniak-Dąbrowska, A. Nowacka, Wojciech Smuczyński, M. Śniegocki

引用次数: 0

IgA deficiency: a risk factor for food allergy-related atopic dermatitis in infants and young children IgA缺乏:婴幼儿食物过敏相关特应性皮炎的危险因素

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2016-10-21 DOI: 10.5114/ADA.2016.62844

Aleksandra Szczawińka-Popłonyk, Paulina Komasińska, A. Bręborowicz

引用次数: 3

Original paper Allergy to propolis in Polish beekeepers 波兰养蜂人对蜂胶过敏

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-12-21 DOI: 10.5114/PDIA.2012.32391

K. Basista, B. Filipek

{"title":"Original paper Allergy to propolis in Polish beekeepers","authors":"K. Basista, B. Filipek","doi":"10.5114/PDIA.2012.32391","DOIUrl":"https://doi.org/10.5114/PDIA.2012.32391","url":null,"abstract":"Introduction: According to the literature propolis is a non-toxic and safe substance. However, propolis can induce allergy. Beekeepers may be the group most affected by contact allergy and propolis is an occupational contact aller gen for them. Aim: To determine the prevalence of propolis contact allergy in beekeepers and theirs families and its possible asso ciation with other coexistent conditions. Material and methods: The questionnaire ‘Allergy to propolis among beekeepers’ was distributed to beekeepers by hand through the Beekeepers Associations, especially the Provincial Association of Apiarists in Krakow. The study was conducted on adults of both genders who had given informed consent to participate in the study. The program Statistica was used for data management and statistical analysis. Results: A total of 2540 questionnaires were distributed, including 1360 questionnaires from Malopolska region. Five hundred and fifty-eight questionnaires were returned, including 345 from Malopolska region. The response rate was 21.97% (25.4% Malopolska region). Among 558 beekeepers propolis contact allergy occurred in 17 cases (3.05%). Four hundred anf four of 558 beekeepers used propolis as a therapeutic agent. Eleven of 404 (2.72%) beekeepers report ed propolis allergy. Only 5 beekeepers reported concomitant propolis allergy after contact with this substance dur ing beekeeping and using propolis as a therapeutic agent. Among 2205 members of families who were using propo lis only 14 patients (0.63%) reported propolis allergy. Conclusions: Allergy to propolis in Polish beekeepers does not seem to be a common phenomenon.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84555801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Case report Pointillist melanotic macules: a new clinical entity? 点状黑斑:一种新的临床实体?

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-12-21 DOI: 10.5114/PDIA.2012.32398

Cheng Tan, Wen‐yuan Zhu

引用次数: 0

Original paper Evaluation of knowledge about acne vulgaris among a selected population of adolescents of Tricity schools 三联体学校青少年对寻常性痤疮知识的评价

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-12-21 DOI: 10.5114/PDIA.2012.32388

K. Tałasiewicz, A. Ołdakowska, A. Szczerkowska-Dobosz

{"title":"Original paper Evaluation of knowledge about acne vulgaris among a selected population of adolescents of Tricity schools","authors":"K. Tałasiewicz, A. Ołdakowska, A. Szczerkowska-Dobosz","doi":"10.5114/PDIA.2012.32388","DOIUrl":"https://doi.org/10.5114/PDIA.2012.32388","url":null,"abstract":"Introduction: It is estimated that approximately 80% of adolescents have different forms of acne vulgaris. Due to the high prevalence of the disease and its psycho-emotional impact on the quality of life, it is important to prevent the spread of misconceptions. Aim:To analyze the basic knowledge and misconceptions concerning acne vulgaris among adolescents. Material and methods: The study included 900 adolescents aged 15-19 years (mean age: 17.47 years), 401 females, 493 males attending high schools ( n= 481) or technical colleges ( n= 419). The study was based on a direct anony mous questionnaire that consisted of fourteen multiple choice questions. Results: On average, 50.3% of questions were answered correctly. 57.8% of participants stated that they had suf fered from acne. As regards the causes, more than half (59.5%) of participants stated that acne is connected to eat ing and hygiene habits. 40.5% of students considered acne infectious. The study revealed that many “false beliefs” exist. 26.4% of adolescents believe that starting sexual activity can influence healing. Considering the effectiveness of curing acne in adolescence, 24.2% of participants do not see a point in early treatment. Regarding the sources of knowledge about acne, most adolescents use the internet, teenage newspapers and friends' opinions. Only 41.2% want to learn more, and almost 90% consider their knowledge sufficient. Conclusions:The results from a large population-based study indicate that the knowledge about acne is insufficient, which reveals the need for introducing educational programs in schools.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83114088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6