Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii最新文献_第5页

Case reports Lymphomas of the head and neck in dermatological practice 病例报告头颈部淋巴瘤在皮肤科实践

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30473

M. Sokołowska-Wojdyło, M. Sikorska, A. Florek, B. Drogoszewska, A. Kowalczyk, A. Starzyńska, A. Szczerkowska-Dobosz, W. Barańska-Rybak, A. Włodarkiewicz

引用次数: 2

Case reports Effective therapy of epidermal growth factor receptor inhibitor-associated dermatologic side effects in a patient with metastatic colorectal cancer: a case report and review of literature 一例转移性结直肠癌患者表皮生长因子受体抑制剂相关皮肤副反应的有效治疗:一例病例报告和文献回顾

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30475

A. Góralczyk, M. Sokołowska-Wojdyło, A. Kowalczyk, A. Szczerkowska-Dobosz, W. Barańska-Rybak

引用次数: 1

Original papers IgA autoantibodies to gliadin nonapeptides, tissue transglutaminase and epidermal transglutaminase are associated, but unrelated to neutrophil elastase expression in lesional skin in human dermatitis herpetiformis 人疱疹样皮炎病变皮肤中抗麦胶蛋白非肽、组织转谷氨酰胺酶和表皮转谷氨酰胺酶的IgA自身抗体与中性粒细胞弹性酶表达相关，但与之无关

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30461

J. Gornowicz‑Porowska, A. Seraszek-Jaros, E. Kaczmarek, M. Dmochowski, M. Bowszyc-Dmochowska

{"title":"Original papers IgA autoantibodies to gliadin nonapeptides, tissue transglutaminase and epidermal transglutaminase are associated, but unrelated to neutrophil elastase expression in lesional skin in human dermatitis herpetiformis","authors":"J. Gornowicz‑Porowska, A. Seraszek-Jaros, E. Kaczmarek, M. Dmochowski, M. Bowszyc-Dmochowska","doi":"10.5114/PDIA.2012.30461","DOIUrl":"https://doi.org/10.5114/PDIA.2012.30461","url":null,"abstract":"Introduction: In dermatitis herpetiformis (DH), activation of neutrophils via IgA Fc receptors (e.g. CD89) and immuno - complexes containing IgA1 may lead to the release of proteolytic enzymes, mainly neutrophil elastase (NE), destruc - tion of the dermal-epidermal junction and blister formation. Aim: To analyze whether there are associations between levels of circulating IgA autoantibodies to epidermal (eTG) and tissue (tTG) transglutaminases, nonapeptides of gliadin (npG) and the intensity of cutaneous NE expression in patients with DH. Material and methods: Altogether, 31 patients with DH were studied. The levels of serum IgA autoantibodies to eTG, tTG and npG were evaluated with ELISAs. The intensity of NE expression was estimated with immunohistochem istry using NE monoclonal antibody and quantitative digital morphometry. Statistical analysis was done using Spear - man's rank correlation coefficient. Results: There were no statistically significant correlations between the intensity of cutaneous NE expression and the levels of serum IgA autoantibodies to eTG, tTG, npG in patients with DH. There were statistically significant cor - relations between the levels of IgA autoantibodies to eTG, tTG, npG. Conclusions: It seems that in human DH the activation of neutrophils, judged by the NE expression, is unrelated to the levels of serum IgA autoantibodies to eTG/tTG/npG, but all those autoantibodies in DH are produced in a coor - dinated way.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76361631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Original papers Self-reported depression and sense of disease in cosmetic patients 美容患者自我报告的抑郁和疾病感

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30466

Joanna Magdziarz-Orlitz, Zofia Gerlicz-Kowalczuk, B. Dziankowska-Bartkowiak

{"title":"Original papers Self-reported depression and sense of disease in cosmetic patients","authors":"Joanna Magdziarz-Orlitz, Zofia Gerlicz-Kowalczuk, B. Dziankowska-Bartkowiak","doi":"10.5114/PDIA.2012.30466","DOIUrl":"https://doi.org/10.5114/PDIA.2012.30466","url":null,"abstract":"Introduction: An increasing number of patients with various personality disorders, psychological problems and depression due to real or imaginary cosmetic defects visit a doctor. Aim: Evaluation of the relationship between cosmetic problems and self-reported depression in individuals elect ing to undergo cosmetic procedures, sense of disease in these individuals as well as the relationship between selfreported disease and depression. Material and methods: Investigations using Beck Depression Inventory (BDI) and Self-Esteem Scale (SES) were car ried out on 167 patients, before and 4 weeks after the procedure. Results: There is a statistically significant difference ( p < 0.001) between mean values of measurements before (9.3 points) and after (6.12 points) surgical procedures. The percentage of patients with different severity of depres sion before the procedure decreased from 42% to 18%. Using SES, the problem was assessed in the following cat egories: Obstacle, Challenge, Threat, Injustice, Benefit and Importance. The difference between mean scores before and following the intervention was 6.52 points and was statistically significant ( p < 0.05). Conclusions: The results obtained confirm that depression has an impact on self-reported disease and in the case of the investigated group it may be assumed that the aesthetic defect is a disease.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87470541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Review papers Diagnosis, clinical assessment of HIV infection in a pregnant woman and legal aspects of HIV infection 综述:孕妇HIV感染的诊断、临床评估和HIV感染的法律方面

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30471

C. Żaba, Maciej Osiński

引用次数: 0

Case reports Soft tissue infection caused by Streptococcus dysgalactiae subsp. equisimilis possessing group Aantigen: a case report and review of the literature 无乳链球菌引起的软组织感染病例报告。具有a群抗原的镰状线虫1例报告及文献复习

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30476

Michał Karyński, Iwona Łętowska, P. Grzesiowski

{"title":"Case reports Soft tissue infection caused by Streptococcus dysgalactiae subsp. equisimilis possessing group Aantigen: a case report and review of the literature","authors":"Michał Karyński, Iwona Łętowska, P. Grzesiowski","doi":"10.5114/PDIA.2012.30476","DOIUrl":"https://doi.org/10.5114/PDIA.2012.30476","url":null,"abstract":"The study presents microbiological characteristics, identification, pathogenicity, epidemiology and antimicrobial susceptibility of Streptococcus dysgalactiae subsp. equisimilis (SDSE). The SDSE shows a close relationship to Streptococcus pyogenes. The SDSE strains usually have a group G antigen, less commonly a group C one. Like S. pyogenes, most of SDSE strains can cause complete hemolysis (β-hemolysis) on a blood agar medium, and some of them possess the same A type of group-specific cell wall antigen. These common phenotype traits lead to confusion between both species. For this reason, microbiological diagnosis of streptococci should not be finished at the stage of serogrouping. A case of soft tissue infection of the left lower limb of a 30-year-old man is described. The etiological factor of the infection was β-hemolytic SDSE of group A. Antimicrobial susceptibility tests revealed that the strain is susceptible to penicillin, erythromycin, clindamycin and levofloxacin, while it is resistant to tetracycline. Treatment with first-generation cephalosporin (cefadroxil) was successfully applied, resulting in a complete remission of the infection symptoms.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73852506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Review papers Treatment of cutaneous infections caused by Mycobacterium tuberculosis 综述:结核分枝杆菌引起皮肤感染的治疗

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30470

N. Wyrzykowska, Michał Wyrzykowski, R. Żaba, W. Silny

{"title":"Review papers Treatment of cutaneous infections caused by Mycobacterium tuberculosis","authors":"N. Wyrzykowska, Michał Wyrzykowski, R. Żaba, W. Silny","doi":"10.5114/PDIA.2012.30470","DOIUrl":"https://doi.org/10.5114/PDIA.2012.30470","url":null,"abstract":"Tuberculosis is still a very common global problem and it is responsible for more than 4,500 deaths every day. The risk of tubercular infection has been estimated to vary from 1% to 2% in developing countries. In the last years, an increased incidence of tuberculosis has been observed, which in countries with a high socio-economic status may be related to the HIV infection prevalence and population migration. The most frequent form of Mycobacteri um tuberculosis infection is tuberculosis of the respiratory system which in Poland accounts for 91.6% of cases. Extra-pulmonary tuberculosis, which includes cutaneous tuberculosis, is rarely observed and its incidence is about 8.4%. With regard to the immunoreactivity or the PPD test and the presence of bacilli, three forms of cutaneous tuberculosis can be distinguished: anergic, reactive and hyperergic. The World Health Organization recommends isoniazid, rifampicin, ethambutol, pyrazinamide and streptomycin as the first-line anti-tuberculosis drugs. This paper is a review of the available present knowledge concerning selected medications, their mechanisms of action and potential adverse effects. Moreover, therapeutic schemes for new tuberculosis patients are also presented.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89295869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Original papers Pathogenic fungi in the work environment of organic and conventional farmers 有机和常规农民工作环境中的病原菌

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30463

W. Żukiewicz-Sobczak, G. Cholewa, E. Krasowska, J. Zwoliński, P. Sobczak, K. Zawiślak, J. Chmielewska-Badora, J. Piątek, A. Wojtyła

{"title":"Original papers Pathogenic fungi in the work environment of organic and conventional farmers","authors":"W. Żukiewicz-Sobczak, G. Cholewa, E. Krasowska, J. Zwoliński, P. Sobczak, K. Zawiślak, J. Chmielewska-Badora, J. Piątek, A. Wojtyła","doi":"10.5114/PDIA.2012.30463","DOIUrl":"https://doi.org/10.5114/PDIA.2012.30463","url":null,"abstract":"Recent research conducted at the Institute of Rural Health indicated the harmfulness of organic dusts present in the environments of agricultural producers. Due to the high concentration of biological agents contained in dust grains, derived from conventional and organic cropping systems, there is a real risk of developing respiratory dis - eases in people doing agricultural work. Conventional and organic cropping systems differ significantly in terms of fertilization method and plant protection. Such differences may also influence the composition of biological agents in grain dust, which can cause various health effects in humans. No assessment has been carried out in farms with different systems of farming. Ambiguous statements on existing health risks in people doing agricul - tural work on conventional and organic farms prompted the Department of Allergy and Environmental Hazards, Institute of Rural Health in Lublin, to perform mycological tests and assess the degree of contamination with fun - gi pathogenic for humans in grain dust and grain from organic and conventional farms. A literature review and research conducted at the Institute of Rural Medicine show that the problem of occupational exposure to the pres - ence of molds and mycotoxins in grains and grain dusts and their possible role in the development of pathological changes of the respiratory system is very important from the standpoint of hygiene and occupational medicine, and still requires further studies.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82031320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Review papers Prevention of recurrent venous ulceration 预防静脉溃疡复发

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30472

M. Szewczyk, Justyna Cwajda-Białasik, A. Jawień

引用次数: 2

Psychological stress and transepidermal water loss in atopic dermatitis: preliminary results 特应性皮炎的心理应激和经皮失水:初步结果

Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii Pub Date : 2012-09-23 DOI: 10.5114/PDIA.2012.30464

Anna Kępska, M. Haftek, A. Nosbaum, P. Pralong, J. Nicolas, F. Bérard, Alicja Ograczyk, A. Zalewska-Janowska

{"title":"Psychological stress and transepidermal water loss in atopic dermatitis: preliminary results","authors":"Anna Kępska, M. Haftek, A. Nosbaum, P. Pralong, J. Nicolas, F. Bérard, Alicja Ograczyk, A. Zalewska-Janowska","doi":"10.5114/PDIA.2012.30464","DOIUrl":"https://doi.org/10.5114/PDIA.2012.30464","url":null,"abstract":"Introduction: Atopic dermatitis (AD) is an inflammatory skin disease in which activation of specific T cells directed towards environmental allergens plays an important role. Environmental allergens' penetration through the skin is facilitated by the skin barrier impairment what causes xerosis and transepidermal water loss (TEWL) increase. As AD is a chronic disease, there are many factors responsible for exacerbations during the course of the disease, including environmental stress. Aim: Evaluation of the correlation between the level of psychological stress and epidermal barrier function in AD patients. Material and methods: Eight AD patients were included in the study during which two consultations were performed in one month's time. During each visit patients completed psychological questionnaires and had TEWL of unin - volved skin measured. The TEWL was also evaluated before and after the educational session which took place dur - ing the first visit. Results: The study did not show any statistically significant correlation between the level of psychological stress, epidermal barrier function (measured by TEWL) and AD severity both at the beginning of the study (before and after the educational session) and a month later (all p> 0.05). Conclusions: Negative observations could result from a small number of participants and a short follow-up period. However, consecutive studies excluding these limitations may play an important role in understanding the influ - ence of stress on the skin barrier in atopic dermatitis and have reliable clinical implications.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72959403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2