牛奶过敏儿童的患者特征表现为对作为消除饮食一部分的广泛水解乳清和/或酪蛋白配方过敏

Z. Nowacki
{"title":"牛奶过敏儿童的患者特征表现为对作为消除饮食一部分的广泛水解乳清和/或酪蛋白配方过敏","authors":"Z. Nowacki","doi":"10.5114/PDIA.2012.32389","DOIUrl":null,"url":null,"abstract":"Introduction: In the recent years the number of children with cow’s milk protein allergy (CMPA) presenting with aller gies to extensively hydrolyzed whey (eHF-W) and casein formulae (eHF-C) respectively has increased. Aim: To present the patient characteristics of children with CMPA who presented with allergic reactions to eHF-W and/or eHF-C used as part of an elimination diet. Material and methods: A retrospective study was carried out for a group of 65 selected from of 359 children (3 to 12 months) affected with CMPA and allergy to eHF. Results: 18.1% (65/359) and 7.8% (28/359) from the group presented with allergic reactions to eHF-W and eHF-C, respectively. An allergic reaction to eHF-C occurred in 43% of the patients from the group (28/65). IgE-mediated CMPA presented with one of the following clinical manifestations: atopic dermatitis (AD) 94%, gastrointestinal symptoms (GI) 47%, respiratory symptoms (RS) 44%, anaphylactic reactions (AR) 26%. Non-IgE-mediated CMPA, on the other hand, manifested with: AD 97%, GI 22%, RS 10% .The observations showed that all 31 from the non-IgE mediated CMPA group with GI and AD manifestations presented with symptoms of eHF-C allergy ( p = 0.001). In the IgE-medi ated CMPA ( n = 34) the following factors were statistically significant with relation to eHF-C allergy: CMPA mani festing with GI ( p = 0.014) and AD. The occurrence of AR in response to cow’s milk protein (CMP) decreased the prob ability of an eHF-C allergy ( p = 0.028) in a statistically significant way. Conclusions: Children with CMPA who presented with allergies to eHF-W and eHF-C had a higher frequency of clin ical manifestation with GI and AD.","PeriodicalId":7212,"journal":{"name":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2012-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Original paper Patient characteristics of children with cow’s milk allergy presenting with an allergy to extensively hydrolyzed whey and/or casein formulae used as part of an elimination diet\",\"authors\":\"Z. Nowacki\",\"doi\":\"10.5114/PDIA.2012.32389\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: In the recent years the number of children with cow’s milk protein allergy (CMPA) presenting with aller gies to extensively hydrolyzed whey (eHF-W) and casein formulae (eHF-C) respectively has increased. Aim: To present the patient characteristics of children with CMPA who presented with allergic reactions to eHF-W and/or eHF-C used as part of an elimination diet. Material and methods: A retrospective study was carried out for a group of 65 selected from of 359 children (3 to 12 months) affected with CMPA and allergy to eHF. Results: 18.1% (65/359) and 7.8% (28/359) from the group presented with allergic reactions to eHF-W and eHF-C, respectively. An allergic reaction to eHF-C occurred in 43% of the patients from the group (28/65). IgE-mediated CMPA presented with one of the following clinical manifestations: atopic dermatitis (AD) 94%, gastrointestinal symptoms (GI) 47%, respiratory symptoms (RS) 44%, anaphylactic reactions (AR) 26%. Non-IgE-mediated CMPA, on the other hand, manifested with: AD 97%, GI 22%, RS 10% .The observations showed that all 31 from the non-IgE mediated CMPA group with GI and AD manifestations presented with symptoms of eHF-C allergy ( p = 0.001). In the IgE-medi ated CMPA ( n = 34) the following factors were statistically significant with relation to eHF-C allergy: CMPA mani festing with GI ( p = 0.014) and AD. The occurrence of AR in response to cow’s milk protein (CMP) decreased the prob ability of an eHF-C allergy ( p = 0.028) in a statistically significant way. Conclusions: Children with CMPA who presented with allergies to eHF-W and eHF-C had a higher frequency of clin ical manifestation with GI and AD.\",\"PeriodicalId\":7212,\"journal\":{\"name\":\"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-12-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5114/PDIA.2012.32389\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/PDIA.2012.32389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

摘要

简介:近年来,牛奶蛋白过敏(CMPA)儿童分别对广泛水解乳清(eHF-W)和酪蛋白配方(eHF-C)过敏的人数有所增加。目的:介绍对eHF-W和/或eHF-C作为消除饮食的一部分出现过敏反应的CMPA患儿的患者特征。材料和方法:从359例患有CMPA和eHF过敏的儿童(3 - 12个月)中选择65例进行回顾性研究。结果:组中分别有18.1%(65/359)和7.8%(28/359)对eHF-W和eHF-C出现过敏反应。该组43%的患者(28/65)发生对eHF-C的过敏反应。ige介导的CMPA临床表现为:特应性皮炎(AD) 94%,胃肠道症状(GI) 47%,呼吸道症状(RS) 44%,过敏反应(AR) 26%。另一方面,非ige介导的CMPA表现为:AD 97%, GI 22%, RS 10%。观察显示,具有GI和AD表现的非ige介导CMPA组31例患者均出现eHF-C过敏症状(p = 0.001)。在ige介导的CMPA (n = 34)中,与eHF-C过敏相关的因素有统计学意义:CMPA与GI (p = 0.014)和AD。对牛奶蛋白(CMP)反应的AR的发生降低了eHF-C过敏的可能性(p = 0.028),具有统计学意义。结论:对eHF-W和eHF-C过敏的CMPA患儿临床表现为GI和AD的频率更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Original paper Patient characteristics of children with cow’s milk allergy presenting with an allergy to extensively hydrolyzed whey and/or casein formulae used as part of an elimination diet
Introduction: In the recent years the number of children with cow’s milk protein allergy (CMPA) presenting with aller gies to extensively hydrolyzed whey (eHF-W) and casein formulae (eHF-C) respectively has increased. Aim: To present the patient characteristics of children with CMPA who presented with allergic reactions to eHF-W and/or eHF-C used as part of an elimination diet. Material and methods: A retrospective study was carried out for a group of 65 selected from of 359 children (3 to 12 months) affected with CMPA and allergy to eHF. Results: 18.1% (65/359) and 7.8% (28/359) from the group presented with allergic reactions to eHF-W and eHF-C, respectively. An allergic reaction to eHF-C occurred in 43% of the patients from the group (28/65). IgE-mediated CMPA presented with one of the following clinical manifestations: atopic dermatitis (AD) 94%, gastrointestinal symptoms (GI) 47%, respiratory symptoms (RS) 44%, anaphylactic reactions (AR) 26%. Non-IgE-mediated CMPA, on the other hand, manifested with: AD 97%, GI 22%, RS 10% .The observations showed that all 31 from the non-IgE mediated CMPA group with GI and AD manifestations presented with symptoms of eHF-C allergy ( p = 0.001). In the IgE-medi ated CMPA ( n = 34) the following factors were statistically significant with relation to eHF-C allergy: CMPA mani festing with GI ( p = 0.014) and AD. The occurrence of AR in response to cow’s milk protein (CMP) decreased the prob ability of an eHF-C allergy ( p = 0.028) in a statistically significant way. Conclusions: Children with CMPA who presented with allergies to eHF-W and eHF-C had a higher frequency of clin ical manifestation with GI and AD.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信