Aging and health research最新文献

{"title":"Intergenerational pathways to oral health: An integrative review","authors":"Mary E. Northridge ,&nbsp;Sara S. Metcalf ,&nbsp;Raghbir Kaur","doi":"10.1016/j.ahr.2026.100273","DOIUrl":"10.1016/j.ahr.2026.100273","url":null,"abstract":"<div><h3>Background</h3><div>The major oral diseases (dental caries, periodontal diseases, and oral cancers) are all relatively prevalent in the global population and largely preventable, while also causing pain and suffering across the life course for socioeconomically disadvantaged populations unable to access quality oral health care.</div></div><div><h3>Methods</h3><div>This review critically examined the extant literature on intergenerational evidence to improve oral health with 4 objectives, namely, to: 1) incorporate older adults into existing multilevel frameworks; 2) include marginalized populations within and across regions of the world to promote oral health equity; 3) ensure that evidence from quantitative, qualitative, and mixed methods studies and reviews was integrated in this research; and 4) identify promising intergenerational pathways to improve oral health at multiple levels of influence and across generations.</div></div><div><h3>Results</h3><div>Forty-four original research studies and 11 evidence-based reviews were identified at all 4 levels (<em>societal/policy, community/neighborhood, family/friends, and individual/population</em>) of the social ecological model titled, <em>Intergenerational pathways to oral health</em> that was refined through this research.</div></div><div><h3>Conclusions</h3><div>The 55 original research studies and evidence-based reviews critically examined in this review add to existing theory by intentionally expanding prior multilevel frameworks to embrace older adults as active participants in intergenerational interventions to improve oral health and health equity.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"6 1","pages":"Article 100273"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social support interventions for life satisfaction of older adults in long-term care: A systematic review and meta-analysis","authors":"Tiffany Yu ,&nbsp;Alex Sy ,&nbsp;Angela Wang ,&nbsp;Mihir Kamra ,&nbsp;Philip Yu ,&nbsp;Tejanth Pasumarthi ,&nbsp;Neha Tangri ,&nbsp;Rebecca L. Morgan","doi":"10.1016/j.ahr.2026.100275","DOIUrl":"10.1016/j.ahr.2026.100275","url":null,"abstract":"<div><h3>Background</h3><div>Older adults residing in long-term care homes often experience isolation, resulting in increased feelings of vulnerability, reduced quality of life, and poorer health outcomes. Social support interventions may serve to mitigate or improve these outcomes; however, the effectiveness of such interventions on life satisfaction has not been formally compared in a systematic review. This systematic review aims to assess the comparative effectiveness of social support-based interventions for adults 65 years and older living in long-term care homes on life satisfaction.</div></div><div><h3>Methods</h3><div>A systematic literature review was conducted in Ovid EMBASE, Ovid MEDLINE, CINAHL, and Cochrane CENTRAL from database inception through November 23, 2025. To be eligible for inclusion, studies had to be comparative and report on the outcome of life satisfaction. Two reviewers screened titles and abstracts, and full-text records independently and in duplicate. Reviewers assessed study limitations using the Cochrane Risk of Bias 2.0 instrument. Certainty of evidence was assessed using the GRADE approach.</div></div><div><h3>Results</h3><div>Of 13,004 records identified, fourteen studies met the eligibility criteria for this review. Social support interventions reported in the literature include life reminiscence program, intergenerational program, music intervention, general support, mentorship program and group activities. Life satisfaction was reported using Life Satisfaction Index (LISA), Life Satisfaction Scale (LSS), Quality of Life Index (QLI), Satisfaction with Life Scale (SWLS), PGC Morale Scale, and Satisfaction with life in the home. Evidence of support intervention effectiveness on life satisfaction was found to be moderate in both randomized (SMD = 0.79 [95% CI, -0.66 to 2.25]) and non-randomized studies (SMD = 0.55 [95% CI, 0.01 to 1.08]) due to concerns with risk of bias and imprecision.</div></div><div><h3>Conclusions</h3><div>This review demonstrates that social support interventions may improve life satisfaction in adults 65 years and older. However, further analysis and research should be conducted.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"6 1","pages":"Article 100275"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced cognitive assessment for dementia in Sub-Saharan Africa: Cultural adaptations and validity","authors":"Tsimona Dinku Bonger ,&nbsp;Zemichael Getu Alemayehu","doi":"10.1016/j.ahr.2025.100269","DOIUrl":"10.1016/j.ahr.2025.100269","url":null,"abstract":"","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"6 1","pages":"Article 100269"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145980864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does body mass index predict changes in body composition and metabolic markers in response to testosterone therapy?","authors":"Maryam Tetlay ,&nbsp;Marcos Villarreal ,&nbsp;Lina Aguirre ,&nbsp;Georgia Colleluori ,&nbsp;FNU Deepika ,&nbsp;Rui Chen ,&nbsp;Dennis T. Villareal ,&nbsp;Clifford Qualls ,&nbsp;Reina Armamento-Villareal","doi":"10.1016/j.ahr.2025.100265","DOIUrl":"10.1016/j.ahr.2025.100265","url":null,"abstract":"<div><h3>Background</h3><div>Despite reported improvements in body composition, metabolic profile, skeletal outcomes and symptoms from testosterone (T) therapy in men with hypogonadism, it remains unclear whether baseline body mass index (BMI) affects response. The objective of this study is to determine if baseline BMI influences response to T therapy.</div></div><div><h3>Methods</h3><div>This is a secondary analysis of data from a clinical trial on pharmacogenetics of response to T therapy in men with average morning <em>T</em> &lt; 300 ng/dl, given intramuscular T cypionate 200 mg every 2 weeks for 18 months. Participants were divided into BMI categories: BMI 1 (&lt; 30 kg/m²), BMI 2 (30–34.99 kg/m²), and BMI 3 (≥35 kg/m²). T, estradiol, adipokines, metabolic markers, body composition, bone mineral density, bone turnover markers and total symptom score were assessed at baseline, 6, 12 and 18 months.</div></div><div><h3>Results</h3><div>All 3 groups had improvement in body composition, though BMI 1 and 2 had greater increases in truncal fat-free and truncal lean mass than BMI 3. Appendicular fat mass declined the most in BMI 1 and the least in BMI 3.. Leptin declined in all 3 groups with the most in BMI 1, while adiponectin significantly decreased only BMI 2. All groups showed increase in lumbar spine BMD. BMI 1 and 2 had improvement in symptoms but not BMI 3.</div></div><div><h3>Conclusion</h3><div>Our study shows that men with a BMI &lt;35 derived the greatest benefit from T therapy in terms of changes in body composition and symptoms, while those with higher BMI benefited the least.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"5 4","pages":"Article 100265"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145322934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Alzheimer’s disease perceptions among Korean Americans through an online community: A text mining approach","authors":"Grace E. Yi ,&nbsp;Michin Hong","doi":"10.1016/j.ahr.2025.100266","DOIUrl":"10.1016/j.ahr.2025.100266","url":null,"abstract":"<div><h3>Background</h3><div>Alzheimer’s disease and related dementia (ADRD) have a profound impact on older adults and their families. Research indicates that racial/ethnic minority groups, including Korean Americans (KAs), encounter disparities in disease prevalence, diagnosis delays, and access to social and healthcare resources. KAs, mostly first-generation immigrants, face unique challenges due to limited English proficiency and cultural differences that impede healthcare access. This study aims to explore discussions about ADRD among KAs to gain insights into their perceptions and experiences.</div></div><div><h3>Methods</h3><div>We analyzed 882 posts from MissyUSA, one of the largest online KAs communities, collected between 2015 and 2023. A text-mining thematic analysis was employed.</div></div><div><h3>Results</h3><div>Four themes emerged: (1) transnational caregiving, (2) the need for culturally and linguistically appropriate care services, (3) the need for caregiving assistance from the public sector, and (4) preventative measures for ADRD.</div></div><div><h3>Conclusions</h3><div>The findings highlight the complex needs of KAs in global contexts. Many participants struggled with finding reliable care information and facilities for parents in the U.S. and Korea, reflecting the challenges of caregiving as immigrants. Locating and accessing culturally and linguistically compatible healthcare services and public support in the U.S. intensified KA caregiving families. Culturally and linguistically tailored public health education to correct misinformation about ADRD and caregiving within this community is needed. Implications for practice and policy are discussed.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"5 4","pages":"Article 100266"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health perceptions and behaviors among aging same-gender Kazakh ethnic minority siblings in rural and urban Xinjiang, China: The impact of migration","authors":"Jing Wang ,&nbsp;Tianjun Zhou ,&nbsp;Yinan Zhang ,&nbsp;Olivia Black ,&nbsp;Xiaolin Wang ,&nbsp;Ruolin Ren ,&nbsp;Morgan Shapiro ,&nbsp;Bei Wu","doi":"10.1016/j.ahr.2025.100264","DOIUrl":"10.1016/j.ahr.2025.100264","url":null,"abstract":"<div><h3>Background</h3><div>This study investigates health perceptions and behaviors among Kazakh-Chinese same-sex siblings in rural and urban Xinjiang, China. It explores how environmental context and migration experiences shape differences in health-related outcomes.</div></div><div><h3>Methods</h3><div>We conducted semi-structured interviews with 24 participants (12 same-gender sibling dyads), with one sibling residing in an urban setting and the other in a rural area. A convergent mixed-methods approach was used, combining qualitative interview data with demographic and health screening information to examine health behaviors and perceptions across environments.</div></div><div><h3>Results</h3><div>Urban siblings demonstrated greater access to healthcare and health literacy but reported challenges including environmental pollution, stress, and diminished traditional social engagement. In contrast, rural siblings maintained traditional dietary habits and robust social rituals but faced limited healthcare access, irregular eating patterns, and more physical labor. Both groups expressed concern about food safety and environmental degradation. Religious and spiritual beliefs were found to influence participants' health behaviors and understanding of well-being.</div></div><div><h3>Conclusions</h3><div>Health outcomes among Kazakh-Chinese older adults are shaped by a complex interplay of cultural tradition, religious belief, and environmental exposure. These findings underscore the need for culturally sensitive, place-based public health strategies to support healthy aging among ethnic minorities undergoing rural–urban transitions.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"5 4","pages":"Article 100264"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145271155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community nurses’ views on information provision at dementia diagnosis: A cross-sectional survey","authors":"Elise Mansfield ,&nbsp;Alison Zucca ,&nbsp;Claudia Meyer ,&nbsp;Jamie Bryant ,&nbsp;Amy Waller","doi":"10.1016/j.ahr.2025.100263","DOIUrl":"10.1016/j.ahr.2025.100263","url":null,"abstract":"<div><h3>Background</h3><div>Receiving a diagnosis of dementia can be overwhelming. Information provided to people with dementia and their support persons following diagnosis is suboptimal. Community nurses have a significant role in providing care to people with dementia.</div></div><div><h3>Method</h3><div>This study examined community nurses’ views on the information that should be provided to people with dementia at diagnosis, and how it should be delivered. Participants completed an online survey including nine items about the type of information that should be delivered at diagnosis, and three items about strategies for information delivery.</div></div><div><h3>Results</h3><div>Most participants (<em>n</em> = 92; 96.7–100 %) agreed with providing information about topics including future dementia symptoms, lifestyle modifications, and Advance Care Directives. Fewer participants (66.3 %) agreed with providing information about probable life expectancy. There was strong support (98.9 %) for offering a follow-up consultation within two weeks of the diagnosis.</div></div><div><h3>Conclusions</h3><div>These findings represent a first exploration of community nurses’ views on optimal dementia care.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"5 4","pages":"Article 100263"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145322935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A double-edged sword: Exploring the neuroprotective/damaging mechanisms of complement activation in Alzheimer's disease","authors":"Jie Wang ,&nbsp;Jie Wu ,&nbsp;Xiaoxi Ma ,&nbsp;Yuhan Wu ,&nbsp;Zhenxu Xiao ,&nbsp;Xiaowen Zhou ,&nbsp;Ding Ding ,&nbsp;Qian-hua Zhao","doi":"10.1016/j.ahr.2025.100267","DOIUrl":"10.1016/j.ahr.2025.100267","url":null,"abstract":"<div><h3>Background</h3><div>Alzheimer's disease (AD), the most widespread neurodegenerative disorder afflicting older adults, is characterized by a progressive decline in cognitive function, behavior, and social skills. The complement system, a cornerstone of the innate immune system, plays a crucial role in rapidly recognizing and clearing foreign pathogens, damaged cells, and cellular debris. Recently, there has been growing interest in understanding the intricate roles of complement components in both normal brain development and neurodegenerative processes.</div></div><div><h3>Methods</h3><div>We reviewed the activation and role of the complement system in AD, specifically highlighting its stage-dependent functional duality, including both protective and detrimental roles. Furthermore, we assessed current and promising therapeutic strategies targeting complement components in AD.</div></div><div><h3>Results</h3><div>The early stage, defined by pre-plaque pathology, was dominated by protective clearance mechanisms, while the progressive phase, characterized by widespread amyloid and tau pathology, exhibited detrimental neuroinflammation and synaptic loss.</div></div><div><h3>Conclusions</h3><div>Understanding the dual roles of the complement system in AD is crucial for developing targeted therapies.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"5 4","pages":"Article 100267"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Errata regarding missing Editor Disclosure statements in previously published articles","authors":"","doi":"10.1016/j.ahr.2025.100260","DOIUrl":"10.1016/j.ahr.2025.100260","url":null,"abstract":"","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"5 4","pages":"Article 100260"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145693159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive impairment and hearing loss in Colombian aged population","authors":"Leonardo Elías Ordóñez Ordóñez ,&nbsp;Daniela Cerón Perdomo ,&nbsp;Gloria Corredor-Rojas ,&nbsp;Jorge Medina-Parra ,&nbsp;Esther Sofía Angulo Martínez","doi":"10.1016/j.ahr.2025.100238","DOIUrl":"10.1016/j.ahr.2025.100238","url":null,"abstract":"<div><h3>Background</h3><div>Hearing loss and cognitive impairment are widely prevalent in individuals aged 60 years and above. Hearing loss is one of the main modifiable risk factors for dementia, emphasizing the importance for potentially mitigating cognitive decline.</div></div><div><h3>Methods</h3><div>This study performed a secondary analysis of the database of Survey on Health, Well-Being, and Aging in Colombia (SABE Colombia). Hearing loss and cognitive impairment were assessed by self-report and the abbreviated Folstein version of the Mini Mental State Examination validated in Latin American Spanish. Information was searched on hearing rehabilitation and access barriers. A logistic regression model was used to assess the impact factors of cognitive impairment.</div></div><div><h3>Results</h3><div>Among 23,694 participants, the estimated prevalence of hearing loss was 31.73 % and for cognitive impairment was 19.79 %, which is similar with global reports. A significant proportion of individuals with hearing loss (93.13 %) remain untreated. There was a statistically significant association between the presence of hearing loss and risk of cognitive impairment (<em>p</em> &lt; 0.001). Older age, fewer years of education, gender (women) and affiliation to subsidized scheme/not being affiliated were also found having significant associations with cognitive impairment (<em>p</em> &lt; 0.001)<strong>.</strong></div></div><div><h3>Conclusions</h3><div>This study offers valuable insights into cognitive impairment and hearing loss and their interrelation in Colombia, thereby assisting government authorities and health system stakeholders in making informed decisions regarding public health policies and resource allocation.</div></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"5 3","pages":"Article 100238"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}