Aging and health research最新文献

{"title":"COVID-19 anxiety: The impact of older adults’ transmission of negative information and online social networks","authors":"Linying Dong ,&nbsp;Lixia Yang","doi":"10.1016/j.ahr.2023.100119","DOIUrl":"10.1016/j.ahr.2023.100119","url":null,"abstract":"<div><h3>Objectives</h3><p>This study examines the impact of older adults’ online social networks on their COVID-19 anxiety, directly or indirectly through social transmission of negative information about COVID-19. Social networks were indexed by both bonding capital (i.e., social relationships formed with family and friends) and bridging capital (i.e., social relationships formed through casual social networks).</p></div><div><h3>Methods</h3><p>An on-line survey was conducted with 190 older adults who were in self-isolation in Ontario in the early waves of the COVID-19 pandemic in 2020.</p></div><div><h3>Results</h3><p>Bonding and bridging capital showed different impacts on older adults’ informational behavior and COVID-19 anxiety. While bonding capital deterred older adults from transmitting negative COVID-19 information and thus reduced COVID-19 anxiety, bridging capital contributed to increased dissemination of negative information and thus heightened older adults’ anxiety.</p></div><div><h3>Discussion</h3><p>Our findings shed light on the detrimental behavioral and psychological impact of casual online social networks on older adults amidst a public health crisis.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"3 1","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10280127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decade in Healthy Ageing in Asia","authors":"Qiushi Feng, Bei Wu","doi":"10.1016/j.ahr.2023.100138","DOIUrl":"https://doi.org/10.1016/j.ahr.2023.100138","url":null,"abstract":"","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47577319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies for the study of neuroepigenetics and aging with a translational approach","authors":"María Araceli Ortiz-Rodríguez ,&nbsp;María Fernanda Martínez-Salazar ,&nbsp;Paola Kattyana Antunez-Bautista ,&nbsp;Angélica Saraí Jiménez-Osorio","doi":"10.1016/j.ahr.2023.100122","DOIUrl":"10.1016/j.ahr.2023.100122","url":null,"abstract":"<div><p>The study of the biological mechanisms of aging is central to increasing knowledge about the susceptibility to the development of diseases associated with advanced age. The advancement of technology has allowed a greater understanding of the intracellular networks that can influence the progression of neurodegenerative diseases. Nevertheless, comprehensive knowledge of the experimental and clinical approaches that impact public health is still needed. The study of the interconnection of the biological components that lead to the development of neurodegenerative diseases should focus on a translational approach that aids in understanding the interindividual differences in terms of the epigenetic characteristics of aging. Therefore, this article discusses the advances in knowledge of the neuroepigenetics of aging and the opportunity to link them to clinical knowledge from a translational approach.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"3 1","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41513372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trust in physicians predicts COVID-19 booster uptake among older adults: Evidence from a panel survey","authors":"Filip Viskupič ,&nbsp;David L. Wiltse","doi":"10.1016/j.ahr.2023.100127","DOIUrl":"10.1016/j.ahr.2023.100127","url":null,"abstract":"","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"3 1","pages":"Article 100127"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10766719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysfunction in the right putamen is associated with drooling in de novo Parkinson's disease","authors":"Hiroki Takatsu,&nbsp;Hidetomo Murakami,&nbsp;Tomotaka Shiraishi,&nbsp;Takeo Sato,&nbsp;Teppei Komatsu,&nbsp;Kenichiro Sakai,&nbsp;Tadashi Umehara,&nbsp;Shusaku Omoto,&nbsp;Hidetaka Mitsumura,&nbsp;Yasuyuki Iguchi","doi":"10.1016/j.ahr.2022.100116","DOIUrl":"10.1016/j.ahr.2022.100116","url":null,"abstract":"<div><p>Drooling is a common and troublesome symptom in Parkinson's disease (PD), but the underlying pathophysiological mechanisms remain unclear. Studies in recent years have suggested each part of the striatum has different functions. Here, we investigated the association between drooling and dopaminergic dysfunction in each part of the striatum among patients with <em>de novo</em> PD. We retrospectively reviewed consecutive enrolled patients who had been diagnosed with <em>de novo</em> PD. Drooling was assessed using the Non-Motor Symptoms Questionnaire item 1. Uptake of ¹²³I-ioflupane in each part of the striatum bilaterally on single positron emission computed tomography was quantitatively evaluated in PD patients with or without drooling. We enrolled 44 PD patients, comprising 12 with drooling and 32 without drooling. Significantly lower uptake of ¹²³I-ioflupane was identified among patients with drooling compared to patients without drooling in the right anterior putamen (median 0.49 vs 0.74, <em>p</em> = 0.004) and right posterior putamen (median 0.23 vs 0.41, <em>p</em> = 0.02). These findings suggest that in PD patients, drooling is associated with dopaminergic dysfunction in the right putamen.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"3 1","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49296235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does GERAS DANCE improve gait in older adults?","authors":"Patricia Hewston ,&nbsp;Steven R Bray ,&nbsp;Courtney C Kennedy ,&nbsp;George Ioannidis ,&nbsp;Jackie Bosch ,&nbsp;Sharon Marr ,&nbsp;Alicia Hanman ,&nbsp;Amanda Grenier ,&nbsp;Genevieve Hladysh ,&nbsp;Alexandra Papaioannou","doi":"10.1016/j.ahr.2023.100120","DOIUrl":"10.1016/j.ahr.2023.100120","url":null,"abstract":"<div><h3>Background</h3><p>Older adults at increased fall risk walk slower with less rhythm and coordination. This study explored the effect of dance on spatiotemporal gait parameters in older adults.</p></div><div><h3>Methods</h3><p>Participants (<em>N</em> = 23) in a single-arm trial were enrolled in the 12-week GERAS DANCE program (total dose of 36 h). Gait was assessed at baseline and 12-weeks under two experimental conditions: normal walking or walking while performing serial subtraction by 3. Outcome measures were gait speed, stride length time, double support time, stride length and stride width. Separate two-way repeated measures ANOVAs were used to determine estimates of the magnitude of effect of GERAS DANCE on spatiotemporal gait parameters and a paired <em>t</em>-test was used to examine differences in cognitive performance before and after dance.</p></div><div><h3>Results</h3><p>Older adults (72.50 ± 7.13 years; 75% female) had excellent attendance (82.73% adherence). GERAS DANCE resulted in increased gait speed (<em>p</em>&lt;0.001), reduced stride length time (<em>p</em> = 0.034), reduced double support time (<em>p</em> = 0.001), increased stride length (<em>p</em> = 0.003) and marginally reduced stride width (<em>p</em> = 0.064), regardless of the experimental condition. Improvements in walking performance were observed with sustained performance on the serial subtraction task before and after GERAS DANCE.</p></div><div><h3>Conclusions</h3><p>GERAS DANCE may be a safe and feasible program to help improve spatiotemporal gait parameters in older adults with early memory or mobility impairments. Next steps include testing the efficacy for fall prevention to help inform clinical practice guidelines and virtual intervention implementation.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"3 1","pages":"Article 100120"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41326064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age accelerated effect of tooth loss on cognitive function among Chinese older adults","authors":"Huashuai Chen ,&nbsp;Yan Yan Wu ,&nbsp;Wei Zhang","doi":"10.1016/j.ahr.2022.100099","DOIUrl":"10.1016/j.ahr.2022.100099","url":null,"abstract":"<div><h3>Objectives</h3><p>Focusing on older adults in China, this study aims to examine the association between tooth loss and cognitive impairment.</p></div><div><h3>Methods</h3><p>This study used six waves of data from the Chinese Longitudinal Healthy Longevity Survey across 16 years and applied generalized estimation equation regression models.</p></div><div><h3>Results</h3><p>Severe tooth loss was significantly related to cognitive impairment after adjusting for sociodemographic characteristics, health behaviors, and self-rated poor health. The adjusted prevalence ratios of cognitive impairment were 1.35 (95%CI: 1.30, 1.40) for edentulousness vs. no or mild tooth loss (0–9), and 1.25 (95%CI: 1.20, 1.30) for severe tooth loss (10 or more) vs. no or mild tooth loss. The effect of tooth loss increased with age from &lt;1% for all three groups to 50.9% for edentulousness, 35.6% for severe tooth loss and 30.7% for no or mild tooth loss.</p></div><div><h3>Discussion</h3><p>This study lends support to the hypothesis that oral health is an important covariate of cognitive impairment. Future studies should continuously explore this topic by adding more objective oral health assessments and speculate potential pathways that may underlie the relationship using high quality longitudinal data.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"2 4","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667032122000452/pdfft?md5=0ca9b47d17bb1b32e02bb23c3cdc6e13&pid=1-s2.0-S2667032122000452-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48748559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in Parkinson's disease with dementia and dementia with Lewy bodies","authors":"Lidadi L. Agbomi ,&nbsp;Chika P. Onuoha ,&nbsp;Samuel I. Nathaniel ,&nbsp;Oreoluwa O. Coker-Ayo ,&nbsp;Melissa J. Bailey-Taylor ,&nbsp;Laurie Theriot Roley ,&nbsp;Nicolas Poupore ,&nbsp;Richard L. Goodwin ,&nbsp;Thomas I. Nathaniel","doi":"10.1016/j.ahr.2022.100096","DOIUrl":"10.1016/j.ahr.2022.100096","url":null,"abstract":"<div><h3>Background</h3><p>Gender differences for dementia with Lewy bodies (DLB), usually considered an intermediate disease between Alzheimer disease (AD), Parkinson disease (PD), and Parkinson disease with dementia (PDD), is controversial. The present study investigated gender differences in DLB and PDD using demographic and pharmacologic treatment strategies in a retrospective data analysis.</p></div><div><h3>Method</h3><p>Data of confirmed cases of DLB and PDD between 2015 and 2020 were collected from the PRISMA dementia data-base registry. Data from 7594 PDD patients and 608 DLB patients were analyzed using logistic regression analysis to determine demographic and pharmacologic factors associated with DLB and PDD patients.</p></div><div><h3>Result</h3><p>In the adjusted analysis, central acetylcholinesterase inhibitors (ChEIs) including donepezil, galantamine, rivastigmine were associated with DLB. Second generation antipsychotics (SGAs) such as risperidone (odd ratio(OR)=1.900, 95% confidence interval (CI),1.192–3.030, <em>P</em> = 0.007) was associated with females with DLB while aripiprazole (OR=0.195,95% CI,0.06–0.631, <em>P</em>&lt;0.006), and a selective serotonin receptor inhibitor (SSRIs) including escitalopram (OR=0.651, 95% CI,0.468–0.906, <em>P</em> = 0.011), and demographic factors including tobacco use (OR=0.620, 95% CI,0.444–0.866, <em>P</em>&lt;0.005) and increasing age (OR =1.042, 95% CI, 1.025–1.058, <em>P</em>&lt;0.001), were associated with females that present with PDD. Olanzapine (OR=2.871, 95% CI, 1.902–4.334, <em>P</em>&lt;0.001), escitalopram (OR=1.444, 95% CI, 1.079–1.932) and tobacco use (OR=1.424, 95%CI, 1.075–1.887, <em>P</em> = 0.014) were associated with males with DLB. African American males (OR= 0.249, 95% CI, 0.088–0.703, <em>P</em> = 0.009) with a history of ethyl alcohol (ETOH) use (OR= 0.371, 95% CI, 0.260–0.531, <em>P</em>&lt;0.001) treated with aripiprazole (OR=0.581, 95%CI, (0.302–1.118), <em>P</em> = 0.004) were associated with PDD.</p></div><div><h3>Conclusion</h3><p>Our findings reveal similarities and differences in demographic and pharmacologic factors associated with DLB and PDD. Investigating the effect of identified factors on DLB or PDD in future studies can help improve the care of DLB and PDD patients.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"2 4","pages":"Article 100096"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667032122000427/pdfft?md5=717795420f8f428ebd2f3a26df163573&pid=1-s2.0-S2667032122000427-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46766430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differential in chronic diseases among older adults in India: Does living arrangement has a role to play?","authors":"Shekhar Chauhan ,&nbsp;Shubham Kumar ,&nbsp;Nayan Jyoti Nath ,&nbsp;Divya Dosaya ,&nbsp;Ratna Patel","doi":"10.1016/j.ahr.2022.100106","DOIUrl":"10.1016/j.ahr.2022.100106","url":null,"abstract":"<div><h3>Background</h3><p>This study examined the prevalence and related factors of four major chronic diseases among older adults in India with a focus on living arrangement and gender.</p></div><div><h3>Methods</h3><p>Longitudinal Ageing Study in India survey data (LASI- Wave I) conducted in 2017–18 was used. This study is based on 31,464 older people aged 60+ years in India. The outcome variables for this study are four chronic diseases namely; Hypertension, Diabetes, Chronic lung diseases, and Chronic heart diseases. Binary logistic regression was used to evaluate the association of diagnosed chronic diseases with socio-demographic and health characteristics.</p></div><div><h3>Results</h3><p>Prevalence rates of chronic heart diseases (5.8% vs. 4.6%), chronic lung diseases (9% vs. 8%), and diabetes (14.6% vs. 13.9%) were higher among the male older adults than in the female older adults. In contrast, the prevalence of hypertension was higher among the female older adults (37.1% vs. 28%) than in the male older adults. The odds of diabetes were lower among the older adults living with spouse and/or others [Odds Ratio (OR)=0.54, 95% Confidence Interval (CI)=0.32–0.91] and living with spouse and children (OR=0.48, 95% CI=0.29–0.81) than living alone. The odds of chronic lung diseases (OR=0.62, 95% CI=0.50–0.78) and chronic heart diseases (OR=0.72, 95% CI=0.54–0.96) were lower among females than in males.</p></div><div><h3>Conclusions</h3><p>Given the higher prevalence of chronic diseases among older adults, there is a need to set-up the geriatric clinics to cater to the needs of the older adult population. Furthermore, special attention should be given to the older adults living alone.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"2 4","pages":"Article 100106"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266703212200052X/pdfft?md5=964f2ad1d32b4b6c00636862246af8c7&pid=1-s2.0-S266703212200052X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42891849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using a systems perspective to understand hospital falls among patients with dementia","authors":"Mary Duah-Owusu White ,&nbsp;Fiona Kelly ,&nbsp;Michael Vassallo ,&nbsp;Samuel R. Nyman","doi":"10.1016/j.ahr.2022.100109","DOIUrl":"10.1016/j.ahr.2022.100109","url":null,"abstract":"<div><h3>Background</h3><p>Falls are a frequent event among older adults with dementia during their hospital stay. This qualitative study explores the factors contributing to falls in this population using a systems perspective.</p></div><div><h3>Methods</h3><p>Semi-structured interviews were conducted with 32 carers of patients with dementia and 20 hospital staff who worked on medical wards. Interview transcripts were analysed thematically using a systems framework.</p></div><div><h3>Results</h3><p>The themes generated from this falls research were factors related to the: patient (e.g. their physical health), carer (e.g. their ability to re-call a patient's past medical history), staff (e.g. teamwork), hospital policies (e.g. transfer of patients between wards), the hospital environment (e.g. lack of observation side rooms for infectious patients who are at risk of falls on some wards) and the use of hospital equipment (e.g. walking aid).</p></div><div><h3>Conclusion</h3><p>We recommend that future hospital falls intervention programmes need to be supported by a credible systems approach aiming to improve patient outcomes in relation to falls prevention.</p></div>","PeriodicalId":72129,"journal":{"name":"Aging and health research","volume":"2 4","pages":"Article 100109"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667032122000555/pdfft?md5=371dbe5f7b88e8796548d406e58ed05e&pid=1-s2.0-S2667032122000555-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41519398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}