André Tadeu Sugawara, Lucas Ramos De Pretto, Marcel Simis, Felipe Fregni, Linamara Rizzo Battistella
{"title":"Primary Motor Area Activity in Phantom Limb Imagery of Traumatic Unilateral Lower Limb Amputees With Phantom Limb Pain.","authors":"André Tadeu Sugawara, Lucas Ramos De Pretto, Marcel Simis, Felipe Fregni, Linamara Rizzo Battistella","doi":"10.1177/27536351241261023","DOIUrl":"10.1177/27536351241261023","url":null,"abstract":"<p><strong>Introduction: </strong>Estimates of the worldwide increase in amputees raises the awareness to solve long-standing problems. Understanding the functional brain modifications after a lower limb amputation (LLA) is one of the first steps towards proposing new rehabilitation approaches. Functional modifications in the central nervous system due the amputation could be involved in prosthesis use failures and Phantom Limb Pain (PLP), increasing costs and overwhelming the health services.</p><p><strong>Objective: </strong>This study analyses orphan primary motor area (M1-Orphan) hemodynamic and metabolic behaviour, which previously controlled the limb that was amputated, in comparison with the M1-Preserved, responsible for the intact limb (IL) during phantom limb imagery moving during Mirror Therapy (MT), compared to Isolated Intact Limb Movement Task (I-ILMT).</p><p><strong>Methodology: </strong>A case-control study with unilateral traumatic LLA with moderate PLP who measured [oxy-Hb] and [deoxy-Hb] in the M1 area by Functional Near InfraredSpectroscopy (fNIRS) during the real (I-ILMT) and MT task.</p><p><strong>Results: </strong>Sixty-five patients, with 67.69% of men, young (40.32 ± 12.91), 65.63% amputated due motorcycle accidents, 4.71 ± 7.38 years ago, predominantly above the knee (57.14%). The M1 activation in the orphan cortex did not differ from the activation in the intact cortex during MT (<i>P</i> > .05).</p><p><strong>Conclusion: </strong>The perception of the Phantom limb moving or intact limb moving is metabolically equivalent in M1, even in the absence of a limb. In other words, the amputation does not alter the brain metabolism in control of phantom movement.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241261023"},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11265251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rhiannon M Smith, Megan E Schliep, Prudence Plummer
{"title":"Perceptions of Communication and Mobility Recovery Among Stroke Survivors With and Without Aphasia.","authors":"Rhiannon M Smith, Megan E Schliep, Prudence Plummer","doi":"10.1177/27536351241237865","DOIUrl":"10.1177/27536351241237865","url":null,"abstract":"<p><p>Self-perceived recovery after stroke can substantially impact quality of life. Yet, a disability paradox exists whereby disability and perceived recovery do not align. This study explored stroke survivors' perceptions of their communication and mobility recovery, including perceived facilitators and barriers. Potential differences between the experiences of participants with aphasia (PWA) and participants without aphasia (PWOA) were also examined to explore the impact of communication disability on recovery experience. Semi-structured interviews were conducted with 17 adults with stroke 3 months after discharge from inpatient rehabilitation. Qualitative data in the form of interview transcripts were analyzed using thematic content analysis. Participants described their communication recovery primarily in terms of word-finding difficulty and slowed language formulation; they described their mobility recovery in terms of their ability to walk, their use of an assistive device, or their ability to participate in pre-stroke activities. Facilitators to recovery were described in the areas of (1) family involvement, (2) rehabilitation services and professionals, (3) personal factors, and (4) the need for self-reliance. Barriers were expressed in the domains of (1) physical difficulties, (2) communication difficulties, and (3) psychological difficulties. Key findings from this study include perceived needs for a high intensity of rehabilitation, earlier implementation of communication partner training for families of stroke survivors with communication impairments, and consideration of factors outside of stroke when tailoring intervention to the individual. Overall, these findings suggest a continued need for individuation rather than standardization of care, with an eye to both impairment and broader quality of life factors.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241237865"},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10958803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140208378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zihao Wang, Bahman Rostami-Tabar, Jane Haider, Mohamed Naim, Javvad Haider
{"title":"Investigating Length of Stay Patterns and Its Predictors in the South Wales Trauma Network.","authors":"Zihao Wang, Bahman Rostami-Tabar, Jane Haider, Mohamed Naim, Javvad Haider","doi":"10.1177/27536351241237866","DOIUrl":"https://doi.org/10.1177/27536351241237866","url":null,"abstract":"<p><strong>Background: </strong>Length of stay (LOS) is frequently employed as a performance metric for trauma care. Following the establishment of the trauma network worldwide, the assessment and prediction of LOS in different levels of trauma centres have been extensively studied. However, assessing the total patient length of stay from a whole trauma network perspective is unclear. The objective of this study was to systematically analyse the overall Length of Stay (LOS) pattern within the SWTN before its establishment and in the immediate time after its foundation and, secondly, to assess the association between relevant impact factors and LOS.</p><p><strong>Methodology: </strong>A retrospective secondary analysis based on the trauma admission dataset from Trauma Audit and Research Network(TARN) dataset was conducted. The studied sample covered around 18000 patients admitted to trauma centres from South Wales Major trauma network between January 2012 and October 2021. The primary outcome is the total length of stay in the trauma network. Statistical tests were applied to examine the difference between normal and outlier LOS. Data visualisation was utilised to demonstrate the LOS patterns and potential association between LOS and relevant demographic and clinical predictors.</p><p><strong>Results: </strong>The distribution of length of stay in SWTN follows a right-skewed distribution with a median of 10 (IQR, 5-18) and a mean of 15.92 days. There were 1520 patients with outliers for LOS. A significant difference (p¡ 0.05) was found between the normal and outlier groups of LOS based on demographic (age, gender and residential information) and clinical characteristics(ward type, maximum of anatomically-based injury severity score(AIS) and probability of survival). Age group, maximum AIS score on specific injured region, ward type and its interaction effect with the number of admissions may associated with the LOS. Specifically, patients admitted to the geriatric ward exhibited notably prolonged LOS, and individuals with more than 2 admissions to long-term care and recovery-related wards such as neurosurgical rehabilitation, spinal injuries and burns wards also displayed elevated LOS.</p><p><strong>Conclusion: </strong>Our finding supports prior evidence indicating elderly people are vulnerable to longer stays. Moreover, concerning the types of admission wards, patients admitted to rehabilitation wards who underwent more than 2 hospitalisations also faced an increased risk of prolonged stay. Based on these results, policymakers and healthcare providers should contemplate expanding the allocation of medical resources to this demographic to mitigate the length of stay and optimise associated healthcare costs.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241237866"},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10949546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alhadi M Jahan, Ali E Rwaiha, Salima M Anaiba, Rasha A Alghoul
{"title":"Cross-Cultural Validation of the Arabic Short-Form McGill Pain Questionnaire (SF-MPQ): Libyan Version in Patients With Musculoskeletal Pain.","authors":"Alhadi M Jahan, Ali E Rwaiha, Salima M Anaiba, Rasha A Alghoul","doi":"10.1177/27536351241233917","DOIUrl":"https://doi.org/10.1177/27536351241233917","url":null,"abstract":"<p><strong>Background: </strong>The Short-form McGill Pain Questionnaire (SF-MPQ) is a widely used tool for assessing musculoskeletal pain, both in research and clinical practice. However, a culturally appropriate Arabic version for the Libyan context has not been available. This study aims to translate the SF-MPQ, and to examine its reliability and validity for assessing musculoskeletal pain in Libya.</p><p><strong>Methods: </strong>The SF-MPQ was cross-culturally adapted into Arabic using a forward-backward method. A total of 151 patients (Mean age ± SD = 40.66 ± 14) with musculoskeletal pain completed the SF-MPQ and other measures. Of these, 148 patients completed the second round of questionnaire completion two days after the first visit. The intraclass correlation coefficient (ICC) was used to examine relative test-retest reliability and Bland-Altman plots was performed to examine absolute agreement between the two assessments. Spearman's correlation was applied to assess construct validity.</p><p><strong>Results: </strong>The Arabic translation of the SF-MPQ was linguistically equivalent, without significant discrepancies. All but two of the Arabic descriptors were used by more than 33% of the participants, indicating good item measurement equivalency. The results showed a satisfactory Cronbach's α (0.74 for the total score), which indicates good internal consistency. The ICC for the total score revealed a high correlation for the test-retest (0.91), suggesting excellent relative reliability. Bland-Altman analyses showed no significant systematic bias between the repeated measurements. There were positive statistically significant correlations among the SF-MPQ, the Visual Analog Scale, and the Fatigue Severity Scale (<i>P</i> < 0.001), demonstrating good construct validity.</p><p><strong>Conclusion: </strong>These results suggest that the Arabic SF-MPQ is reliable, valid, and cross-culturally equivalent to the original SF-MPQ for evaluating musculoskeletal pain among Arabic-speaking patients in Libya. Clinicians and researchers may therefore consider using this scale, as it is easy to use and understand by different age groups. Further research is needed to confirm our findings and to test the developed Arabic version of the SF-MPQ on different patient populations.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241233917"},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10893841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A New Professional Society for Post-COVID Condition and Other Post-Viral Conditions.","authors":"Manoj Sivan, Melissa Heightman","doi":"10.1177/27536351241231351","DOIUrl":"https://doi.org/10.1177/27536351241231351","url":null,"abstract":"","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241231351"},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lene Klem Olesen, Karen la Cour, Laura Nimmon, Heidi With, Charlotte Handberg
{"title":"Experiences of an Online Palliative Rehabilitation Programme for Spousal Caregivers of People With Amyotrophic Lateral Sclerosis and Cognitive and/or Behavioural Impairments: A Qualitative Interpretive Study.","authors":"Lene Klem Olesen, Karen la Cour, Laura Nimmon, Heidi With, Charlotte Handberg","doi":"10.1177/27536351241227860","DOIUrl":"https://doi.org/10.1177/27536351241227860","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to understand how spousal caregivers of people with amyotrophic lateral sclerosis and cognitive and/or behavioural impairments felt about the EMBRACE intervention.</p><p><strong>Materials and methods: </strong>A qualitative interpretive study, using individual semi-structured interviews pre- and post-participation in a palliative rehabilitation blended learning programme, was applied. In total, 13 spousal caregivers were interviewed pre-intervention and 10 of them post-intervention.</p><p><strong>Results: </strong>Three overarching themes were identified: <i>Striving to Obtain Control in Everyday Life, Peer support Across the Illness Trajectory and The Complexity of Relations</i>. Information provided in targeted videos and sharing experiences with peers in virtual group meetings were beneficial to comprehend, manage and find meaning in everyday challenges related to being a caregiver.</p><p><strong>Conclusion: </strong>The EMBRACE intervention helped spousal caregivers cope with everyday needs and challenges related to being a caregiver. EMBRACE was found to support and strengthen the participants in gaining more control in everyday life, creating a sense of coherence. Through targeted videos and discussions with peers, the participants felt prepared for the illness trajectory of their relative. Peer support promoted resilient functioning and reduced their feelings of loneliness.</p><p><strong>Clinical trial registration: </strong>This study was registered on clinicaltrials.gov under the name: A Complex Intervention Study on a Palliative Rehabilitation Blended Learning Programme to Support Relatives and Health Care Providers of People with ALS and Cognitive Impairments in Coping with Challenges. ID no. NCT04638608. URL: https://clinicaltrials.gov/ct2/results?cond=&term=NCT04638608&cntry=&state=&city=&dist=.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241227860"},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Getting up With Lateral Thinking.","authors":"Anita Patel, Stephen Kirker","doi":"10.1177/27536351241229952","DOIUrl":"https://doi.org/10.1177/27536351241229952","url":null,"abstract":"<p><strong>Introduction: </strong>Falls in the community can have major impacts on patient lives. There can be long lasting physical and psychological consequences of a fall and subsequent long lie. The annual burden to ambulance services responding to falls at home is high. Affordable devices to help people get up from the floor, or reduce the risk of a long lie, would be useful and widely applicable.</p><p><strong>Case report: </strong>We present the case of 2 families who successfully used an air mattress and a bath lift to get the fallen person up off the floor following a fall, when they had previously called an ambulance. This has reduced their dependence on the ambulance service and has improved their confidence following falls.</p><p><strong>Discussion/conclusion: </strong>Affordable devices such as air mattresses can help people off the floor following a fall and prevent long lies as well as reduce the number of ambulance call outs.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241229952"},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joanna Corrado, Nafi Iftekhar, Stephen Halpin, Mengyao Li, Rachel Tarrant, Jennifer Grimaldi, Alexander Simms, Rory J O'Connor, Alex Casson, Manoj Sivan
{"title":"HEART Rate Variability Biofeedback for LOng COVID Dysautonomia (HEARTLOC): Results of a Feasibility Study.","authors":"Joanna Corrado, Nafi Iftekhar, Stephen Halpin, Mengyao Li, Rachel Tarrant, Jennifer Grimaldi, Alexander Simms, Rory J O'Connor, Alex Casson, Manoj Sivan","doi":"10.1177/27536351241227261","DOIUrl":"10.1177/27536351241227261","url":null,"abstract":"<p><strong>Introduction: </strong>Post-COVID-19 syndrome, or Long Covid (LC) refers to symptoms persisting 12 weeks after the COVID-19 infection. LC comprises a wide range of dysautonomia symptoms, including fatigue, breathlessness, palpitations, dizziness, pain and brain fog. This study tested the feasibility and estimated the efficacy, of a Heart Rate Variability Biofeedback (HRV-B) programme via a standardised slow diaphragmatic breathing technique in individuals with LC.</p><p><strong>Methods: </strong>LC patients underwent a 4-week HRV-B intervention for 10 minutes twice daily for 4 weeks using the Polar H10 ECG (Electrocardiogram) chest strap and Elite HRV phone application. Outcome measures C19-YRSm (Yorkshire Rehabilitation Scale modified), Composite Autonomic Symptom Score (COMPASS-31), WHO Disability Assessment Schedule (WHODAS), EQ5D-5L (EuroQol 5 Dimensions) and Root Mean Square of Successive Differences between heartbeats (RMSSD) using a Fitbit device were recorded before and after the intervention. The study was pre-registered at clinicaltrials.gov NCT05228665.</p><p><strong>Results: </strong>A total of 13 participants (54% female, 46% male) completed the study with high levels of independent use of technology, data completeness and intervention adherence. There was a statistically significant improvement in C19YRS-m (<i>P</i> = .001), COMPASS-31 (<i>P</i> = .007), RMSSD (<i>P</i> = .047), WHODAS (<i>P</i> = .02) and EQ5D Global Health Score (<i>P</i> = .009). Qualitative feedback suggested participants could use it independently, were satisfied with the intervention and reported beneficial effects from the intervention.</p><p><strong>Conclusion: </strong>HRV-B using diaphragmatic breathing is a feasible intervention for LC. The small sample size limits generalisability. HRV-B in LC warrants further exploration in a larger randomised controlled study.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"13 ","pages":"27536351241227261"},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10826406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giada Milani, Linda Mantovani, Andrea Baroni, Nicola Lamberti, Nino Basaglia, Susanna Lavezzi, Fabio Manfredini, Sofia Straudi
{"title":"Variations in Health-Related Quality of Life After Stroke: Insights From a Clinical Trial on Arm Rehabilitation With a Long-Term Follow-Up.","authors":"Giada Milani, Linda Mantovani, Andrea Baroni, Nicola Lamberti, Nino Basaglia, Susanna Lavezzi, Fabio Manfredini, Sofia Straudi","doi":"10.1177/27536351231214845","DOIUrl":"10.1177/27536351231214845","url":null,"abstract":"<p><p>Despite rehabilitation, stroke patients continue to have impaired function and reduced health-related quality of life (HRQoL) even in a chronic stage. However, no clear information is available on long-term variations in HRQoL. In this study, we aimed to report the short- and long-term changes in HRQoL in a subacute stroke sample that was enrolled in a clinical trial on arm rehabilitation. Thirty-nine stroke survivors (62% male, mean age 68 years) were assessed using the Stroke Impact Scale Version 2.0 (SIS 2.0) pre and post rehabilitation and at 6 months and 6 years follow-up. Long-term changes in physical function were explored through clinically meaningful changes in the Stroke Impact Scale-16 (SIS-16). After rehabilitation (<i>P</i> < .001), an overall improvement was found in all SIS domains except the memory and thinking, emotions, and communication domains. The baseline SIS-16 score (<i>P</i> < .001), the presence of a sensory deficit, and rehabilitation setting (<i>P</i> < .05) were factors related to the SIS-16 domain scores at the end of rehabilitation and at 6 months follow-up. Patients showed the most deterioration in the mobility (<i>P</i> < .001), strength (<i>P</i> < .003), and hand function (<i>P</i> < .05) domains 6 years after stroke. Stroke severity, male gender, and age ⩾65 years are related with a long-term HRQoL reduction after stroke.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"12 ","pages":"27536351231214845"},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Importance of Health Policy and Systems Research for Strengthening Rehabilitation in Health Systems: A Call to Action to Accelerate Progress.","authors":"Walter R Frontera, Wouter DeGroote, Abdul Ghaffar","doi":"10.1177/27536351231214307","DOIUrl":"10.1177/27536351231214307","url":null,"abstract":"","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":"12 ","pages":"27536351231214307"},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}