Giada Milani, Linda Mantovani, Andrea Baroni, Nicola Lamberti, Nino Basaglia, Susanna Lavezzi, Fabio Manfredini, Sofia Straudi
{"title":"Variations in Health-Related Quality of Life After Stroke: Insights From a Clinical Trial on Arm Rehabilitation With a Long-Term Follow-Up.","authors":"Giada Milani, Linda Mantovani, Andrea Baroni, Nicola Lamberti, Nino Basaglia, Susanna Lavezzi, Fabio Manfredini, Sofia Straudi","doi":"10.1177/27536351231214845","DOIUrl":null,"url":null,"abstract":"<p><p>Despite rehabilitation, stroke patients continue to have impaired function and reduced health-related quality of life (HRQoL) even in a chronic stage. However, no clear information is available on long-term variations in HRQoL. In this study, we aimed to report the short- and long-term changes in HRQoL in a subacute stroke sample that was enrolled in a clinical trial on arm rehabilitation. Thirty-nine stroke survivors (62% male, mean age 68 years) were assessed using the Stroke Impact Scale Version 2.0 (SIS 2.0) pre and post rehabilitation and at 6 months and 6 years follow-up. Long-term changes in physical function were explored through clinically meaningful changes in the Stroke Impact Scale-16 (SIS-16). After rehabilitation (<i>P</i> < .001), an overall improvement was found in all SIS domains except the memory and thinking, emotions, and communication domains. The baseline SIS-16 score (<i>P</i> < .001), the presence of a sensory deficit, and rehabilitation setting (<i>P</i> < .05) were factors related to the SIS-16 domain scores at the end of rehabilitation and at 6 months follow-up. Patients showed the most deterioration in the mobility (<i>P</i> < .001), strength (<i>P</i> < .003), and hand function (<i>P</i> < .05) domains 6 years after stroke. Stroke severity, male gender, and age ⩾65 years are related with a long-term HRQoL reduction after stroke.</p>","PeriodicalId":72107,"journal":{"name":"Advances in rehabilitation science and practice","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687933/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in rehabilitation science and practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/27536351231214845","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"0","JCRName":"REHABILITATION","Score":null,"Total":0}
引用次数: 0
Abstract
Despite rehabilitation, stroke patients continue to have impaired function and reduced health-related quality of life (HRQoL) even in a chronic stage. However, no clear information is available on long-term variations in HRQoL. In this study, we aimed to report the short- and long-term changes in HRQoL in a subacute stroke sample that was enrolled in a clinical trial on arm rehabilitation. Thirty-nine stroke survivors (62% male, mean age 68 years) were assessed using the Stroke Impact Scale Version 2.0 (SIS 2.0) pre and post rehabilitation and at 6 months and 6 years follow-up. Long-term changes in physical function were explored through clinically meaningful changes in the Stroke Impact Scale-16 (SIS-16). After rehabilitation (P < .001), an overall improvement was found in all SIS domains except the memory and thinking, emotions, and communication domains. The baseline SIS-16 score (P < .001), the presence of a sensory deficit, and rehabilitation setting (P < .05) were factors related to the SIS-16 domain scores at the end of rehabilitation and at 6 months follow-up. Patients showed the most deterioration in the mobility (P < .001), strength (P < .003), and hand function (P < .05) domains 6 years after stroke. Stroke severity, male gender, and age ⩾65 years are related with a long-term HRQoL reduction after stroke.
尽管康复,中风患者仍然有功能受损和健康相关生活质量(HRQoL)下降,即使在慢性阶段。然而,没有关于HRQoL长期变化的明确信息。在这项研究中,我们的目的是报告一个亚急性中风样本的短期和长期HRQoL的变化,该样本参加了一项关于手臂康复的临床试验。39名中风幸存者(62%男性,平均年龄68岁)在康复前后以及随访6个月和6年时使用中风影响量表2.0版(SIS 2.0)进行评估。通过卒中影响量表-16 (SIS-16)的临床意义变化来探讨身体功能的长期变化。康复后(P P P P P P