Advances in nutrition (Bethesda, Md.)最新文献

{"title":"Measuring Cocoverage in Global Health and Nutrition Interventions: A Scoping Review of Analytical Approaches.","authors":"Swetha Manohar, Samantha Grounds, Sunny S Kim, Niharika Pandya, Taylor Morrison, Phuong Hong Nguyen","doi":"10.1016/j.advnut.2026.100742","DOIUrl":"10.1016/j.advnut.2026.100742","url":null,"abstract":"<p><p>Multisectoral nutrition (MSN) approaches coordinate interventions across sectors, such as health, agriculture, education, and social protection, to improve nutrition outcomes and have gained prominence in low- and middle-income countries (LMICs). Measuring cocoverage-the clustering of multiple interventions at the individual and household level-remains uncommon yet offers a viable method for tracking MSN intervention coverage. This scoping review examined existing analytic approaches and applications for assessing the cocoverage of health and nutrition interventions. We searched Web of Science Core Collection, PubMed, and EBSCOhost for studies that used, described, or developed cocoverage methods to measure nutrition- and health-related intervention coverage. Titles and abstracts were screened by 2 independent reviewers using Covidence, followed by full-text screening based on predefined criteria. Screening 4478 abstracts yielded 73 eligible studies applying 8 distinct methods to quantify cocoverage across health and nutrition interventions. Most studies were observational (90%) and conducted in LMICs, particularly sub-Saharan Africa and South Asia, with publications increasing over the past decade. Data were primarily drawn from surveys (93%), particularly Demographic and Health Surveys (41 studies). Commonly included individual-level interventions in cocoverage indices were antenatal care (ANC, 66 studies) or ANC components, child immunizations (48 studies), and skilled birth attendance (42 studies). Evidence on measuring a range of multisectoral interventions at the household level was limited. Intervention selection was often guided by established frameworks or guidelines. Coverage indices were calculated using simple counts, weighted averages, and scoring systems. Although 18 studies validated their indices through methods such as Cohen's κ and sensitivity analyses, most relied on previously used approaches without specific validation. These findings underscore the considerable variability in cocoverage methodologies and the need for greater harmonization and validation to enable consistent monitoring of multisectoral nutrition progress.</p>","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100742"},"PeriodicalIF":9.2,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Comment on \"Artificial Intelligence in the Management of Malnutrition in Cancer Patients: A Systematic Review\".","authors":"Shriraghavan Madbushi, Satish Tukaram Pokharkar, Yogesh Golhar","doi":"10.1016/j.advnut.2026.100739","DOIUrl":"10.1016/j.advnut.2026.100739","url":null,"abstract":"","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100739"},"PeriodicalIF":9.2,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to S Madbushi et al.","authors":"Marco Sguanci, Sara Morales Palomares, Fabio Petrelli, Elena Sandri, Gaetano Ferrara, Stefano Mancin, Giovanni Cangelosi","doi":"10.1016/j.advnut.2026.100740","DOIUrl":"10.1016/j.advnut.2026.100740","url":null,"abstract":"","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100740"},"PeriodicalIF":9.2,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward International Dietary Guidance: A Food Guide Pyramid for Human and Planetary Health.","authors":"Karen A Della Corte, Anette E Buyken, Carlo La Vecchia, Marie-Ann Vanginkel, Jordi Salas-Salvadó, Gabriele Riccardi, Antonia Trichopoulou, Joanne Slavin, Antonio Ceriello, Mònica Bulló, Ulf Risérus, Peter R Ellis, Arne Astrup, Alan Barclay, John L Sievenpiper, Laura Chiavaroli, Simin Liu, Cyril Wc Kendall, Geoffrey Livesey, David Ja Jenkins, Jennie C Brand-Miller, Walter C Willett, Livia Sa Augustin","doi":"10.1016/j.advnut.2026.100738","DOIUrl":"10.1016/j.advnut.2026.100738","url":null,"abstract":"<p><p>Dietary guidelines shape food policy, education, and food systems worldwide. Recent controversies in dietary guideline development, together with rising burdens of diet-related chronic disease and increasing environmental pressures, highlight the need for globally relevant dietary guidance aligned with both human and planetary health. We developed an evidence-informed International Food Guide Pyramid emphasizing optimal carbohydrate-containing staple foods. The International Carbohydrate Quality Consortium developed the proposed framework using a 4-step evidence-review process involving comparison of major national and regional dietary guideline systems, integration of evidence syntheses and selected primary studies, and expert consensus. Quantitative intake ranges from the EAT-Lancet Commission reference diet informed the relative visual proportions of food groups, whereas the guiding principles were derived from convergence across dietary guideline systems and complementary evidence syntheses. The resulting pyramid depicts a plant-forward omnivorous dietary pattern supported by epidemiological and clinical evidence indicating benefits for cardiometabolic health and chronic disease prevention. Vegetables, fruits, whole grains, and legumes constitute foundational components of the pyramid. Nuts, seeds, and unsaturated plant oils are emphasized as primary fat sources, whereas foods high in saturated fat are generally limited. Animal-source foods are included in modest amounts, with plant protein sources emphasized, poultry and fish preferred over red meat, and dairy incorporated in modest amounts, consistent with dietary patterns associated with lower environmental impacts. Carbohydrate quality is emphasized through the prioritization of whole-grain foods alongside traditional low-glycemic index grain staples, favoring carbohydrate sources rich in dietary fiber, intact plant cells, and micronutrients while limiting sugars consumed in low-nutrient forms, particularly sugar-sweetened beverages. The framework also accommodates vegan and other primarily plant-based dietary patterns. This evidence-informed International Food Guide Pyramid integrates quantitative modeling and qualitative evidence synthesis to provide a coherent, flexible, and globally adaptable dietary framework aligned with both human and planetary health.</p>","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100738"},"PeriodicalIF":9.2,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149032184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to MA da Silva Araújo et al.","authors":"Cristiana Berti, Mario Cb Raviglione, Carlo Agostoni","doi":"10.1016/j.advnut.2026.100736","DOIUrl":"10.1016/j.advnut.2026.100736","url":null,"abstract":"","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100736"},"PeriodicalIF":9.2,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Climate Change, Food Insecurity, and Pediatric Health: A Developmental Perspective.","authors":"Marcos Antônio da Silva Araújo, Raul Manhães-de-Castro, Joaci Pereira Dos Santos Júnior, Ana Elisa Toscano","doi":"10.1016/j.advnut.2026.100735","DOIUrl":"10.1016/j.advnut.2026.100735","url":null,"abstract":"","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100735"},"PeriodicalIF":9.2,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to L Zhao and N Zhang.","authors":"Aishwarya S Borkar, Yvanna Todorova, Oonagh Markey","doi":"10.1016/j.advnut.2026.100722","DOIUrl":"10.1016/j.advnut.2026.100722","url":null,"abstract":"","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100722"},"PeriodicalIF":9.2,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Reconsidering the Leap from a Single-Trial-Driven Estimate to a Moderate-Certainty LDL Cholesterol Claim for Milk Fat Globule Membrane.","authors":"Lifen Zhao, Nianzhu Zhang","doi":"10.1016/j.advnut.2026.100721","DOIUrl":"10.1016/j.advnut.2026.100721","url":null,"abstract":"","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100721"},"PeriodicalIF":9.2,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fermented Foods in Canada: A Perspective on Research Evidence, Policy, and Future Priorities.","authors":"Carla Liria Sánchez-Lafuente, Michael Gänzle, Marco Gobbetti, Andrea Hardy, Hannah Holscher, Robert Hutkins, Remco Kort, Robin J Marles, George Paraskevakos, Dalia Perelman, Kathryn J Burton-Pimentel, Gregor Reid, Mary Ellen Sanders, Sandra Saville, Gabriel Vinderola, Benjamin P Willing, Raylene A Reimer, Jeremy P Burton","doi":"10.1016/j.advnut.2026.100719","DOIUrl":"10.1016/j.advnut.2026.100719","url":null,"abstract":"<p><p>Fermented foods are attracting renewed scientific, public, and policy interest because of their appealing sensory qualities and their potential health benefits, particularly in light of emerging research on microbiome-diet interactions and food-derived bioactive compounds. Despite their long history of consumption and cultural significance, fermented foods remain largely absent from national dietary guidance in Canada. Although emerging evidence suggests that fermented foods may contribute to health, important uncertainties remain regarding mechanisms of action, product-specific effects, and the strength of evidence across health outcomes. This perspective synthesizes insights from the inaugural workshop of the Canadian Fermented Foods Initiative, integrating viewpoints from microbiology, nutrition, clinical research, policy, industry, and patient partners. We argue that progress in this field requires moving beyond broad, category-level claims toward mechanism-informed, well-characterized research that reflects the biological and cultural diversity of fermented foods. Drawing on both the published literature and workshop discussions, key priorities are identified, including improved characterization of fermented-food interventions, clearer alignment between evidence generation and regulatory standards, and greater integration of culturally grounded research approaches. Workshop discussions highlighted the potential value of complementary study designs, including pragmatic trials and citizen science approaches, for evaluating fermented foods within real-world dietary patterns, although their role in future dietary guidance frameworks remains to be established. Finally, we outline a coordinated national pathway to strengthen the evidence base, support responsible science communication, and facilitate the credible integration of fermented foods into dietary guidance and public health strategies.</p>","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100719"},"PeriodicalIF":9.2,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Mild-to-Moderate Iodine Deficiency With Thyroid Function-A Systematic Review and Meta-analysis.","authors":"Tonje Eiane Aarsland, Inger Aakre, Tonje Holte Stea, Sigrun Henjum, Maria Wik Markhus, Tor A Strand, Lisbeth Dahl, Tim Im Korevaar, Kjersti S Bakken, Synnøve Næss Sleire","doi":"10.1016/j.advnut.2025.100471","DOIUrl":"10.1016/j.advnut.2025.100471","url":null,"abstract":"<p><p>The only known function of iodine in the human body is as a component of thyroid hormones. Thus, all consequences of iodine deficiency should be mediated through altered thyroid hormone production. Although it is well established that severe iodine deficiency affects thyroid hormone production, the association between mild-to-moderate iodine deficiency and thyroid function remains unclear. This review aimed to review and summarize observational studies that examine the association between mild-to-moderate iodine deficiency and thyroid hormone function in the general population, including infants, children, adolescents, adults, pregnant and lactating women. Systematic searches of the literature were performed in November 2022 and repeated in February 2024 using the Medline Ovid, Embase Ovid, and Cochrane Central databases. Mild-to-moderate iodine deficiency was defined as a median urinary iodine concentration (UIC) of 20-100 μg/L in children, adolescents, and general adults, and 50-150 μg/L in pregnant women. Thyroid function outcomes included thyroid-stimulating hormone (TSH), free thyroxine (fT3), and free triiodothyronine (fT4) and clinical thyroid dysfunction entities. A total of 72 studies were included: 59 cross-sectional, 12 repeated cross-sectional (longitudinal), and 1 cohort study. Populations studied included infants, children, and adolescents (n = 7); women of reproductive age, including lactating women (n = 5); general adults (n = 20); and pregnant women (n = 43). For all population groups, most studies found no clear association between iodine status and thyroid function. Meta-analyses for 8 studies in pregnant women showed no difference in TSH, fT4, or fT3 for those with mild-to-moderate iodine deficiency compared with adequate status [mean difference (95% CI): TSH, 0.03 (-0.05, 0.12) mIU/L; fT4, -0.20 (-0.94, 0.53) pmol/L; fT3, 0.05 (-0.14, 0.03) pmol/L]. In conclusion, no clear association between mild-to-moderate iodine deficiency and thyroid function in the different population groups was found. This trial was registered at www.crd.york.ac.uk/PROSPERO as CRD42022360447.</p>","PeriodicalId":72101,"journal":{"name":"Advances in nutrition (Bethesda, Md.)","volume":" ","pages":"100471"},"PeriodicalIF":9.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12351339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}