P.C. Luna , R.A. Pérez-Córdova , M.E. Abad , A. Almassio , N. Atamari-Anahui , M. Larralde
{"title":"Características clínico-epidemiológicas y tratamiento de la psoriasis palmoplantar en niños argentinos","authors":"P.C. Luna , R.A. Pérez-Córdova , M.E. Abad , A. Almassio , N. Atamari-Anahui , M. Larralde","doi":"10.1016/j.ad.2024.01.026","DOIUrl":"10.1016/j.ad.2024.01.026","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages 436-438"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Pindado-Ortega , R. Pirmez , D.F. Melo , L.J.F. Binato , M.L. Porriño-Bustamante , J.B. Carpi , R. Gil-Redondo , Á. Hermosa-Gelbard , J. Jiménez-Cauhé , D. Saceda-Corralo , S. Vaño-Galván
{"title":"Minoxidil oral en dosis bajas en alopecia frontal fibrosante: serie de 122 pacientes","authors":"C. Pindado-Ortega , R. Pirmez , D.F. Melo , L.J.F. Binato , M.L. Porriño-Bustamante , J.B. Carpi , R. Gil-Redondo , Á. Hermosa-Gelbard , J. Jiménez-Cauhé , D. Saceda-Corralo , S. Vaño-Galván","doi":"10.1016/j.ad.2024.05.029","DOIUrl":"10.1016/j.ad.2024.05.029","url":null,"abstract":"<div><div>The objective of our study was to analyze the effectiveness of oral minoxidil on the frontotemporal hairline in patients with FFA. We conducted a retrospective, descriptive, multicenter study in 2 Brazilian and 1 Spanish centers. Responses were graded on a scale of 3 positive points. A total of 122 patients were included. Subjective improvement in the density of the frontotemporal hairline was observed in 45.1% patients, which was categorized as mild (34.4%), moderate (9.0%), and excellent (1.6%). Hair density improved in 57.4% of the patients’ interparietal. Additionally, 25.4% and 3.3% of the patients experienced eyebrow and eyelash growth, respectively. Adverse effects were detected in 33.6% patients, with hypertrichosis being the most common (23.8%). In this study, oral minoxidil proved to be an additional therapy for FFA that not only improved the patients’ overall hair and eyebrow growth, but also the density of the frontotemporal hairline.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages 407-411"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Torrelo Fernández , A. Vicente , A. Martin-Santiago , R. de Lucas Laguna , J.C. Armario-Hita , R. Moro , S. Díaz-Cerezo , L. Lizán , M. Núñez
{"title":"[Artículo traducido] Carga humanística y económica de la dermatitis atópica en los pacientes pediátricos en España: una revisión sistemática","authors":"A. Torrelo Fernández , A. Vicente , A. Martin-Santiago , R. de Lucas Laguna , J.C. Armario-Hita , R. Moro , S. Díaz-Cerezo , L. Lizán , M. Núñez","doi":"10.1016/j.ad.2025.01.005","DOIUrl":"10.1016/j.ad.2025.01.005","url":null,"abstract":"<div><div>Atopic dermatitis (AD) is a chronic, inflammatory skin disease affecting all age groups, particularly children. This systematic review provides an overview of the humanistic and economic disease burden in the pediatric population with AD in Spain. The evidence, collected from 11 observational studies published over the past 10 years, exhibits the most common characteristics of the patients, disease burden, patient-reported outcomes, use of resources, and treatment patterns. The burden of AD extends beyond physical symptoms, with associated comorbidities such as asthma and impaired health-related quality of life and mental health disorders, particularly in severe cases. Traditional therapies, primarily topical corticosteroids, face adherence and efficacy challenges. Despite promising innovative treatments and available biological therapies, their use is still limited in the pediatric population. The findings of the present review highlight the scarce scientific evidence on the economic burden of pediatric AD, as well as the most updated humanistic evidence on this disease. At the same time, the need for individualized care and innovative therapeutic interventions to address the multifaceted challenges of pediatric AD in Spain is evident.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages T365-T377"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Artículo traducido] Tumor de crecimiento lento en la región ilíaca derecha en una niña de 11 años","authors":"C. Correia , M. Pinho , S. Fernandes","doi":"10.1016/j.ad.2025.01.003","DOIUrl":"10.1016/j.ad.2025.01.003","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages T415-T417"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. García-González , L. Prieto-Torres , M. García-García
{"title":"Actualización en procesos linfoproliferativos cutáneos relacionados con el virus de Epstein Barr: revisión sistemática","authors":"S. García-González , L. Prieto-Torres , M. García-García","doi":"10.1016/j.ad.2024.09.018","DOIUrl":"10.1016/j.ad.2024.09.018","url":null,"abstract":"<div><div>Epstein Barr virus (EBV) positive B lymphoproliferative disorders (LPD) with cutaneous involvement include a series of rare entities that go from indolent processes to aggressive lymphomas. B-cell EBV+ LPD mainly affect immunocompromised patients while T-cell EBV+ LPD are more prevalent in specific geographic regions such as Asia, Central America, and South America. Since the latest WHO-EORTC classification of cutaneous lymphomas in 2018, significant changes have been included in the new classifications of hematological malignancies. This systematic review summarizes the main clinical, histological, immunophenotypic and molecular characteristics of B- and T-cell EBV+ LPD that may compromise the skin at diagnosis. B-cell EBV+ LPD include primary cutaneous lymphomas such as EBV-Mucocutaneous Ulcer, as well as systemic lymphomas affecting the skin at diagnosis that may present such as lymphomatoid granulomatosis (LG), EBV diffuse large B cell lymphoma, NOS, plasmablastic lymphoma (PBL), Extracavitary primary effusion lymphoma (EC-PEL) EBV+, EBV-positive polymorphic B cell LPD, and post-transplant lymphoproliferative disorders (PTLD). Regarding T-cell EBV+ LPD, most of these entities are categorized within T/NK-cell lymphoproliferative processes and lymphomas of childhood, including extranodal T/NK lymphoma, and even more exceptional forms such as EBV-positive T-cell centrofollicular lymphoma and intravascular T/NK-cell lymphoma. Diagnosis is based on integrating the clinical, histological, immunohistochemical, and genetic criteria discussed throughout this article. Differential diagnosis is a challenge for dermatologists and pathologists, so having scientific evidence available in this field is of paramount importance because overtreatment must be carefully avoided.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages 378-393"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F.J. Melgosa-Ramos , A. Vicente Villa , I. Betlloch Mas , S. Santos-Alarcón
{"title":"[Artículo traducido] Efectividad y seguridad a medio plazo de upadacitinib en adolescentes con dermatitis atópica moderada a grave: un estudio multicéntrico en práctica clínica (34 pacientes)","authors":"F.J. Melgosa-Ramos , A. Vicente Villa , I. Betlloch Mas , S. Santos-Alarcón","doi":"10.1016/j.ad.2025.01.004","DOIUrl":"10.1016/j.ad.2025.01.004","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages T439-T441"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}