Actas dermo-sifiliograficas最新文献

{"title":"Idiopathic localized cold urticaria: An unusual abdominal presentation and review of reported cases.","authors":"J Ruiz Sánchez, N Martos Bianqui, O Alwattar-Ceballos, J F Silvestre","doi":"10.1016/j.ad.2026.104749","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104749","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104749"},"PeriodicalIF":2.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149190763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractory Dermatomyositis Treated With Anifrolumab: Clinical Response and Dynamics of Type-I Interferon Signature","authors":"M.E. Gimeno-Ribes,&nbsp;A. Mensa-Vilaro,&nbsp;J.I. Aróstegui,&nbsp;S. Prieto-González,&nbsp;J.C. Milisenda,&nbsp;X. Bosch-Amate,&nbsp;J.M. Mascaró Jr.","doi":"10.1016/j.ad.2026.104679","DOIUrl":"10.1016/j.ad.2026.104679","url":null,"abstract":"<div><div>Dermatomyositis (DM) is a systemic inflammatory disease predominantly affecting the skin and muscles, with potential involvement of internal organs. Despite multiple therapeutic options, treatment response may be unsatisfactory. Type-I interferon (IFN) signaling pathways have been proposed as key drivers of disease pathogenesis. Consequently, treatment with anifrolumab, a monoclonal antibody targeting IFN receptor-1, may offer therapeutic benefit. To date, only a few cases of refractory DM successfully treated with anifrolumab have been reported. We present two cases of refractory DM treated with anifrolumab achieving an almost complete cutaneous response. Longitudinal evaluation of the type-I IFN signature revealed a decrease during treatment. These findings support the hypothesis that type-I IFN plays a pathogenic role in DM, especially in patients with refractory disease. In this context, we aim to highlight the importance of considering anifrolumab as a therapeutic option and underscore the potential of the IFN signature as a biomarker of treatment response.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"117 9","pages":"Article 104679"},"PeriodicalIF":2.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147959543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erythema papulatum centrifugum: a clinically distinct dermatosis.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1016/j.ad.2026.104741","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104741","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104741"},"PeriodicalIF":2.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CUDERMA project: Delphi consensus on quality indicators for certification of dermatology units providing care for hidradenitis suppurativa.","authors":"A Martorell, F J García Martínez, A Molina Leyva, L Salgado-Boquete, J F Melgosa Ramos, M Robles-Plaza, A de la Cuadra-Grande, E Vilarrasa","doi":"10.1016/j.ad.2026.104743","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104743","url":null,"abstract":"<p><strong>Objective: </strong>The AEDV CUDERMA project aims to certify dermatology units to standardize clinical practice and ensure quality of care. In line with previous initiatives in psoriasis and dermato-oncology, this study aimed to reach consensus on the aspects to be assessed through quality indicators for the certification of hidradenitis suppurativa (HS) units.</p><p><strong>Methods: </strong>A literature review and a focus group involving dermatologists specializing in the management of patients with HS were conducted to develop a preliminary set of quality indicators, which were subsequently reviewed by a multidisciplinary group of experts. The relevance of these preliminary indicators was then evaluated by a Delphi panel comprising 43 members of the Spanish Hidradenitis Suppurativa Working Group.</p><p><strong>Results: </strong>The Delphi panel reached consensus on the inclusion of 52 quality indicators.</p><p><strong>Conclusion: </strong>These indicators will subsequently be standardized for the development of the certification standard for HS units.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104743"},"PeriodicalIF":2.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intralesional bleomycin versus cryotherapy for the treatment of common warts: a systematic review and meta-analysis of randomized controlled trials.","authors":"D A Lucero Calvache, L C Peláez Vélez, C L Maldonado Carrasco, E Loayza","doi":"10.1016/j.ad.2026.104742","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104742","url":null,"abstract":"<p><strong>Background: </strong> Cryotherapy is a well-established treatment for common warts. However, the efficacy of bleomycin in the treatment of this condition is less well established. Therefore, we conducted a meta-analysis to compare the efficacy of bleomycin versus cryotherapy for the treatment of common warts.</p><p><strong>Methods: </strong> PubMed, Scopus, and Cochrane databases were searched for randomized controlled trials that compared bleomycin with cryotherapy for the management of common warts and reported the outcomes of (1) lack of complete clinical clearance at the patient level (patients with at least 1 residual wart at the end of follow-up) and (2) proportion of warts not completely cleared at the lesion level. Heterogeneity was examined using the I² statistic. A random-effects model was used for outcomes with high heterogeneity.</p><p><strong>Results: </strong> We included 4 randomized controlled trials (RCTs) with 489 patients, of whom 247 (50.2%) received bleomycin. Follow-up intervals ranged from 2 to 3 weeks, with a maximum follow-up of 12 weeks; therefore, only short-term outcomes were available. Lack of complete clinical clearance at the patient level (RR, 1.26; 95%CI, 1.16-1.38; P < .00001; Figure 2A) and the proportion of warts not completely cleared at the lesion level (RR, 1.13; 95%CI, 1.05-1.21; P= .0006; Figure 2B) were significantly more common in patients treated with cryotherapy than in those treated with bleomycin.</p><p><strong>Conclusions: </strong> In patients with common warts, intralesional bleomycin may be associated with higher short-term clearance than cryotherapy. However, these short-term findings are based on a very small number of heterogeneous randomized controlled trials with follow-up of up to 12 weeks, and recurrence and long-term cure could not be assessed. The certainty of the evidence is therefore low, and the results should be interpreted with great caution. In clinical practice, any potential gain in short-term clearance with intralesional bleomycin needs to be weighed against its greater procedure-related pain and local adverse events, as well as factors such as accessibility, clinical expertise, and individual patient preferences.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104742"},"PeriodicalIF":2.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acro-osteolysis and the relevance of mat-like telangiectasia in scleroderma.","authors":"Y Singh Pathania","doi":"10.1016/j.ad.2026.104740","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104740","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104740"},"PeriodicalIF":2.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Onychomycosis: clinical and dermoscopic characteristics, diagnosis, and therapeutic management.","authors":"L Navarro Campoamor, M Iglesias-Sancho, E Jiménez Blázquez","doi":"10.1016/j.ad.2026.104735","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104735","url":null,"abstract":"<p><p>Onychomycosis is a chronic and recurrent nail infection whose worldwide prevalence continues to increase, affecting 5%-10% of the general population and up to 50% of individuals older than 70 years. Despite the availability of multiple effective therapeutic options, current management practices remain suboptimal, and recurrence rates continue to be high. Recent evidence points to persistent shortcomings in clinical practice, including the underuse of confirmatory diagnostic tests, which entails a greater risk of diagnostic errors, and the frequent initiation of empirical treatment without prior etiological verification, which is associated with treatment failure and resistance, lack of adherence, and persistence of infection. Overall, onychomycosis remains a prevalent and complex clinical problem whose control requires greater diagnostic accuracy, rational use of antifungal agents, and standardized strategies for follow-up and prevention of recurrence.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104735"},"PeriodicalIF":2.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erythematous dorsal plaques in 6 patients with advanced T-cell lymphoma: a clinical variant of mogamulizumab-associated rash.","authors":"C Calvo-Asín, P L Ortiz-Romero, J L Rodríguez-Peralto, D Falkenhain-López","doi":"10.1016/j.ad.2026.104739","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104739","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104739"},"PeriodicalIF":2.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tinea barbae in MSM: coincidence or causality?","authors":"Tristán Gabriel Sobral-Costas, Rafael Escudero-Tornero, Patricia Roces Álvarez, Elena Sendagorta Cudos","doi":"10.1016/j.ad.2026.104738","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104738","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104738"},"PeriodicalIF":2.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse events associated with topical corticosteroid use in moderate-to-severe atopic dermatitis: a prospective analysis from the BIOBADATOP registry.","authors":"P Díaz-Calvillo, R Ruiz-Villaverde, J F Silvestre-Salvador, M Espasandín-Arias, M Rodríguez-Serna, A Gonzalez-Quesada, Y Gilaberte-Calzada, C Mauleón-Fernández, P Chicharro, J J Pereyra-Rodríguez, E Herrera-Acosta, T Montero-Vilchez, M Elosua-González, L Curto-Barredo, I García-Doval, M Á Descalzo-Gallego, J M Carrascosa","doi":"10.1016/j.ad.2026.104732","DOIUrl":"https://doi.org/10.1016/j.ad.2026.104732","url":null,"abstract":"<p><p>The long-term safety of topical corticosteroids (TCS) in atopic dermatitis (AD) continues to generate uncertainty and has been identified as a research priority. This study aimed to prospectively evaluate adverse events (AEs) associated with TCS use in the BIOBADATOP registry. A total of 660 patients were included, of whom 484 (73.3%) used TCS at baseline and/or during follow-up. The median baseline EASI score was 21, and baseline disease severity was similar between TCS users and non-users. During TCS treatment, AEs were reported in 4 of 484 patients (0.8%; 95%CI, 0.2-2.1%), all of which were mild: striae, pityriasis sicca of the scalp, hypertension, and mild hypertriglyceridemia. These real-world findings support the safety profile of TCS and make it difficult to justify descriptions of large populations as being intolerant to, or at increased risk from, TCS.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":"104732"},"PeriodicalIF":2.9,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148987572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}