R Gutiérrez-Meré, A R Trapote Cubillas, J A Sánchez Lázaro, J Castiñeiras González
{"title":"Botulinum Toxin Treatment for Plantar Hyperhidrosis Via Peripheral Nerve Blockade at Ankle Level.","authors":"R Gutiérrez-Meré, A R Trapote Cubillas, J A Sánchez Lázaro, J Castiñeiras González","doi":"10.1016/j.ad.2024.10.072","DOIUrl":"https://doi.org/10.1016/j.ad.2024.10.072","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Prat-Colilles, J J Lluch-Galcerá, M Martinez-Molina, J M Carrascosa Carrillo
{"title":"Sporotrichoid Lymphocutaneous Presentation in Ulcerative Cutaneous Alternariosis: A Phaeohyphomycosis Case in a Renal Transplant.","authors":"E Prat-Colilles, J J Lluch-Galcerá, M Martinez-Molina, J M Carrascosa Carrillo","doi":"10.1016/j.ad.2023.12.010","DOIUrl":"https://doi.org/10.1016/j.ad.2023.12.010","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Muntaner-Virgili, C Torrecilla-Vall-Llossera, M Bonfill-Ortí, I Figueras-Nart
{"title":"Effectiveness and safety in the use of Janus kinase inhibitors in combination with other classic or biological systemic treatments: real-world clinical practice experience.","authors":"C Muntaner-Virgili, C Torrecilla-Vall-Llossera, M Bonfill-Ortí, I Figueras-Nart","doi":"10.1016/j.ad.2025.02.025","DOIUrl":"https://doi.org/10.1016/j.ad.2025.02.025","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Prevention Measures in Venereology: Evidence Review on the DoxiPrEP/PEP Antibiotic and the 4CMenB Vaccine.","authors":"A Català, J Riera, I Fuertes de Vega","doi":"10.1016/j.ad.2024.11.028","DOIUrl":"https://doi.org/10.1016/j.ad.2024.11.028","url":null,"abstract":"<p><p>Sexually transmitted infections (STIs) are increasing in Spain. The traditional strategy for STI control is mainly based on screening and treatment of STIs in patients with risky sexual practices. In recent years, new interesting primary and secondary prevention strategies are being studied to reduce the incidence rate of STIs in high-risk populations. The most interesting one, based on the evidence obtained, is the use of doxycycline and meningococcal B vaccines. Specialists in dermatology and venereology must be informed about these new developments that may have an impact on the way in which STIs are managed worldwide. This is a scientific evidence review of these new interesting primary and secondary prevention strategies to control STIs in a high-risk population.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M L Santos E Silva Caldeira Marques, J Mercader Salvans, M M Pestana Eliche
{"title":"Large Painful Plaque in the Perianal Region.","authors":"M L Santos E Silva Caldeira Marques, J Mercader Salvans, M M Pestana Eliche","doi":"10.1016/j.ad.2024.02.040","DOIUrl":"https://doi.org/10.1016/j.ad.2024.02.040","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bullous Lesions After Total Knee Arthroplasty.","authors":"G G Dradi, E Gómez de la Fuente, E García Zamora","doi":"10.1016/j.ad.2023.11.024","DOIUrl":"https://doi.org/10.1016/j.ad.2023.11.024","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital Cutis Aplasia Associated With a Papyraceous Fetus.","authors":"A Giacaman, C Nadal Lladó, A Martín-Santiago","doi":"10.1016/j.ad.2023.11.025","DOIUrl":"https://doi.org/10.1016/j.ad.2023.11.025","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Fernández-de-Misa, M Montes-de-Oca, I Loizate, N Hernández-Hernández
{"title":"Multiple Basal Cell Carcinomas. Timeline and Underlying Risk Factors.","authors":"R Fernández-de-Misa, M Montes-de-Oca, I Loizate, N Hernández-Hernández","doi":"10.1016/j.ad.2024.10.070","DOIUrl":"https://doi.org/10.1016/j.ad.2024.10.070","url":null,"abstract":"<p><strong>Introduction: </strong>Between 29% and 53% of the patients who develop basal cell carcinoma (BCC) will develop new BCCs.</p><p><strong>Objectives: </strong>Current objectives are to analyze the proportion and basic characteristics of patients who develop BCC> 1, to delineate the concept of multiple BCC (mBCC) and be able to identify the factors associated with its development, and analyze its timeframe.</p><p><strong>Patients and method: </strong>We conducted a retrospective observational study including all patients diagnosed with sporadic BCC from January 1<sup>st</sup>, 2014 through December 31<sup>st</sup>, 2014 at a tertiary referral center. Data included dates of BCCs, gender, age and histology of the first BCC, and the presence of BCC> 1 at the initial appointment (cluster<sup>+</sup>). mBCC was defined as a patient who developed a series of BCCs> the 75<sup>th</sup> percentile of the series.</p><p><strong>Results: </strong>A total of 758 patients (51.2% men), were included. After a median follow-up of 100 months, 52.8% of the patients developed BCC> 1. The 75<sup>th</sup> percentile of the number of BCCs was 3. Factors associated to mBCCs included being cluster<sup>+</sup> (OR, 5.6; 95%CI, 3.2 - 9.7), being men (OR, 3.1; 95%CI, 2.0 - 4.8) and diagnosed with the first BCC between ages of 50 and 80 years (OR, 2.1; 95%CI, 1.3 - 3.5). After 5 years, 54% of patients exhibiting these 3 factors developed mBCC. The estimated median time to mBCC was 38.00 months (95%CI, 0 - 79.71).</p><p><strong>Conclusions: </strong>A quarter of patients who Exhibit 1 BCC eventually develop 4 or more BCCs. Analyzing routine parameters may help identify individuals at a higher risk of developing mBCC and predict its timeframe.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unraveling the Link Between Bullous Pemphigoid and Neurological Disease: A Single-center Study of 257 Patients.","authors":"L M Nieto-Benito, R Suárez-Fernández","doi":"10.1016/j.ad.2024.10.071","DOIUrl":"10.1016/j.ad.2024.10.071","url":null,"abstract":"<p><strong>Background: </strong>Multiple studies have corroborated the association between bullous pemphigoid (BP) and neurological diseases; patients with both diseases (BP-N) have been associated with a worse prognosis and specific clinical and immunological characteristics, defining a different subtype of BP.</p><p><strong>Objectives: </strong>We aimed to determine the prevalence and characteristics of BP cases with neurological comorbidities (BP-N) and review the related published literature.</p><p><strong>Methods: </strong>We conducted a retrospective, observational study of BP cases treated at a referral center for autoimmune blistering diseases from January 2000 through June 2020.</p><p><strong>Results: </strong>We collected epidemiological, clinical, histopathological, progression and laboratory data from a total of 257 cases, 102 of which were BP-N. Senile dementia, Alzheimer's disease and vascular dementia were the most frequent neurological comorbidities. Compared with cases without neurological comorbidities, BP-N cases had more intense tissue eosinophilia (p=0.012) and higher concentrations of circulating eosinophils (p=0.000), and anti-BP180 IgG antibodies (p=0.007). At the time of data collection, 78 BP-N were deceased.</p><p><strong>Conclusions: </strong>Our case series highlighted the relevance of neurological comorbidities in BP patients; although the pathogenesis is still to be elucidated, the neuroinflammation present in neurodegenerative diseases could explain the neurocutaneous link and the chronological relationship between these entities.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}