Actas dermo-sifiliograficas最新文献

Pyoderma Gangrenosum and Systemic Lupus Erythematosus: An Uncommon Association. 坏疽性脓皮病和系统性红斑狼疮：一种罕见的关联。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-04 DOI: 10.1016/j.ad.2024.02.044

J Lorca-Spröhnle, A Casanova-Esquembre, C Labrandero-Hoyos, A Pérez-Ferriols

引用次数: 0

Patient with neuropathic ulcers and morphea treated with apremilast. 阿普米司特治疗神经性溃疡和吗啡患者。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-04 DOI: 10.1016/j.ad.2024.02.045

L M Guzmán, J Montero, C Gutiérrez, C Postigo

引用次数: 0

DNA Repair Enzymes for Actinic Keratoses and Keratinocyte Cancer: A Systematic Review of Treatment and Prevention Utility. DNA修复酶治疗光化性角化病和角化细胞癌：治疗和预防应用的系统综述。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2025.03.032

M Claudia Matei, T Gracia-Cazaña, M Almenara Blasco, L Bernal Masferrer, Y Gilaberte

引用次数: 0

Neutrophil Extracellular Trap (NET) Markers in Psoriasis: Linking with Disease Severity and Comorbidities. 银屑病中性粒细胞胞外陷阱（NET）标志物：与疾病严重程度和合并症相关

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2024.10.076

J Arroyo-Andrés, A Gotor Rivera, B Díaz-Benito, A Moraga, I Lizasoain Hernández, R Rivera-Díaz

{"title":"Neutrophil Extracellular Trap (NET) Markers in Psoriasis: Linking with Disease Severity and Comorbidities.","authors":"J Arroyo-Andrés, A Gotor Rivera, B Díaz-Benito, A Moraga, I Lizasoain Hernández, R Rivera-Díaz","doi":"10.1016/j.ad.2024.10.076","DOIUrl":"10.1016/j.ad.2024.10.076","url":null,"abstract":"Psoriatic patients have shown higher levels of neutrophil extracellular traps (NETs) vs healthy controls. Psoriasis is often associated with other comorbidities such as cardiovascular disease. An increase in indirect markers of NETs has been found in patients with increased cardiovascular events in patients without psoriasis.We conducted a prospective observational study with psoriatic patients. A total of 39 of patients were included. Myeloperoxidase, neutrophil elastase and double-stranded DNA were significantly higher in patients with severe-to-moderate vs mild psoriasis. Myeloperoxidase was also significantly higher in patients of moderate high vs low cardiovascular risk (p = .01) in patients with mild psoriasis. Patients with psoriatic arthritis show higher myeloperoxidase levels higher vs those without arthritis (p = .048). Myeloperoxidase was also significantly correlated (p = .0375) with the patients' BMI.The detection of NETs through indirect markers (Myeloperoxidase, neutrophil elastase and double-stranded DNA) is associated with the severity of psoriasis. In addition, myeloperoxidase can be useful in psoriatic patients as biomarkers of comorbidities.","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144566980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Designing and Validating a Questionnaire on Photoprotection in Children and Families. 儿童及家庭光防护问卷的设计与验证。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2024.10.080

J E Muñoz Negro, A Cabrera-León, A Buendía Eisman

{"title":"Designing and Validating a Questionnaire on Photoprotection in Children and Families.","authors":"J E Muñoz Negro, A Cabrera-León, A Buendía Eisman","doi":"10.1016/j.ad.2024.10.080","DOIUrl":"10.1016/j.ad.2024.10.080","url":null,"abstract":"Background and objective: Primary prevention is the only way to reduce the incidence rate of skin cancer. With this objective, we designed and evaluated the questionnaire's feasibility, validity, and reproducibility on photoprotective behaviors and their associated variables in the child population and their families.Material and methods: After reviewing the literature, a group of experts drafted the first questionnaire, analyzing its logical and content validity in 109 participants. A new questionnaire was obtained from this analysis, examining its internal validity through factor analysis and internal consistency (n = 98). Finally, reproducibility was determined in 32 participants who had previously answered the questionnaire.Results: Our questionnaire was easy or very easy for 75% of the study population (mean time, 12 minutes). The following 4 factors were obtained for parents (total explained variance = 61.7%): \"photoprotection of fathers and mothers\"; \"personal vulnerability to sun exposure\"; \"information received on photoprotection and healthy lifestyle habits,\" and \"sun exposure schedule\". For children, a total of 4 factors were also obtained (variance = 61.3%): \"perceived vulnerability and sun protection behavior\"; \"barriers to sun protection\"; \"other barriers\"; and \"beliefs of mothers and fathers and sunburns in their children\". On the other hand, significant changes were only observed in 5 questions. The results of each fieldwork produced improved versions of the questionnaire until its final version was obtained.Conclusion: The questionnaire was a viable, valid, and reproducible instrument to measure sun protection behavior in children and their families.","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144566977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic pruritus of unknown origin: a therapeutic approach. 来源不明的慢性瘙痒：一种治疗方法。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2024.10.079

A Vidal Ruiz, T Ojeda-Vila, D Moreno-Ramírez

引用次数: 0

The Reality of Migration by Patera Boats: Morbidity and Dermatological Injuries. 偷渡移民的现实：发病率和皮肤损伤。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2024.10.075

E de la Rosa-Fernández, P Llansó-Florentí, P Laynez-Roldán, S Garrido-Ríos, J González-Rodríguez, E Benítez-García, I Loizate-Sarrionandia, R Fernández-de-Misa Cabrera

{"title":"The Reality of Migration by Patera Boats: Morbidity and Dermatological Injuries.","authors":"E de la Rosa-Fernández, P Llansó-Florentí, P Laynez-Roldán, S Garrido-Ríos, J González-Rodríguez, E Benítez-García, I Loizate-Sarrionandia, R Fernández-de-Misa Cabrera","doi":"10.1016/j.ad.2024.10.075","DOIUrl":"10.1016/j.ad.2024.10.075","url":null,"abstract":"Background and objectives: The Canary Islands (Spain) serve as the entry point to the EU for thousands of people each year, many of whom arrive by sea in small boats known as \"pateras.\" The extreme conditions of the journey often result in complex clinical presentations upon arrival.Objective: To evaluate the characteristics of patients admitted to a tertiary referral center after a journey in a patera boat.Materials and methods: We conducted a retrospective cross-sectional observational study including migrant patients after a journey in a patera boat who required admission to CHUNSC during 2023. The study evaluates the care pathway and the patients' epidemiological, clinical, and evolutionary characteristics.Results: A total of 484 patients were treated in the emergency department. A total of 93 (19.2%) required admission, the mean age was 23 years old, and 85 (91.4%) were men. The mean length of stay was 29 days. A total of 22 patients (23.6%) were admitted to the ICU for a mean 7.6 days. The most common clinical conditions upon admission were anemia (73.1%) and rhabdomyolysis (62.5%). A total of 76 patients exhibited skin lesions (81.7%), predominantly on the legs (68.4%), feet (67.1%), and buttocks and sacrum (56.6%). A total of 36 (38.7%) underwent surgery; debridement of skin necrosis was performed in 22, skin grafts in 21, and amputations in 12. A total of 35 positive cultures were obtained, with S. aureus, P. aeruginosa, and S. algae being the most frequently isolated pathogens.Conclusions: The extreme conditions of the journey in a patera lead to complex and severe clinical scenarios, with skin and soft tissue lesions often determining the prognosis. Therefore, it is essential to adequately manage these conditions and any associated comorbidities.","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144566983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bicalutamide Mesotherapy: A Novel Alternative for Androgenetic Alopecia. 比卡鲁胺疗法：雄激素性脱发的新选择。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2024.10.078

C F Caballero-Linares, F J Rodríguez-Cuadrado

引用次数: 0

New Horizons for the Puzzle Flap: A Multicenter Review of 35 Cases. 拼图皮瓣的新视野：35例的多中心回顾。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2024.10.074

L Bascón Rodríguez, M E Iglesias Zamora, F J de León Marrero, L Turrión-Merino, A Tejera-Vaquerizo, P J Navarro-Guillamón, P Rodríguez-Jiménez, E Rodríguez Lomba, F Russo de la Torre, I García-Doval, A Guilabert Vidal, J Romaní de Gabriel

{"title":"New Horizons for the Puzzle Flap: A Multicenter Review of 35 Cases.","authors":"L Bascón Rodríguez, M E Iglesias Zamora, F J de León Marrero, L Turrión-Merino, A Tejera-Vaquerizo, P J Navarro-Guillamón, P Rodríguez-Jiménez, E Rodríguez Lomba, F Russo de la Torre, I García-Doval, A Guilabert Vidal, J Romaní de Gabriel","doi":"10.1016/j.ad.2024.10.074","DOIUrl":"10.1016/j.ad.2024.10.074","url":null,"abstract":"Introduction: The advancement flap known as the puzzle flap was first introduced by Goldberg et al. in 2005 as an alternative for small defects on the nasal ala. Although initially designed for this area, its application has been extended to other facial locations, such as the melolabial fold, auricular tragus and temple, with satisfactory aesthetic results.Material and methods: The present retrospective study analyzed a total of 35 cases of puzzle flaps performed by dermatologists across Spain using the multicenter case collection platform known as CLINI-AEDV.Results: Most patients were women, with a mean age of 70 years. Basal cell carcinoma was the most common histological diagnosis. The most common tumor location was the nasal tip with 14 cases being reported out of 35, followed by other areas such as the nasal wing, the nasolabial fold and the retroauricular fold. Most cases, around 90%, did not exhibit immediate or late complications, with the trapdoor effect standing out as the most common complication among the rare ones. There were no recurrences of the excised lesions at the follow-up.Discussion: This study highlights the usefulness of puzzle flap in the reconstruction of facial defects, especially in the nasal tip and adjacent areas, as well as its successful application in other less common facial locations. Its low complication rate and absence of recurrences suggest that this technique can be considered a valid option in the surgical arsenal of every dermatologist for the reconstruction of facial skin defects.","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144566981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erythema Papulatum Centrifugum: A Clinically Distinct Dermatosis. CLINI-AEDV Case Series. 离心性丘疹红斑：一种临床明显的皮肤病。临床- aedv病例系列。

IF 3.8

Actas dermo-sifiliograficas Pub Date : 2025-07-03 DOI: 10.1016/j.ad.2024.10.077

F Allegue, Ander Zulaica, M A Pastor-Nieto, I Ballester-Nortes, V Fernández-Tapia, M E Parera-Amer, I García-Doval

引用次数: 0