E Carmona-Rocha, C Díaz Torné, A M Laiz Alonso, L Puig
{"title":"[[Translated article]]Methotrexate-Induced Gouty Arthritis in Psoriatic Patient.","authors":"E Carmona-Rocha, C Díaz Torné, A M Laiz Alonso, L Puig","doi":"10.1016/j.ad.2025.10.010","DOIUrl":"https://doi.org/10.1016/j.ad.2025.10.010","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Allegue, Ander Zulaica, M A Pastor-Nieto, I Ballester-Nortes, V Fernández-Tapia, M E Parera-Amer, I García-Doval
{"title":"[[Translated article]]Erythema Papulatum Centrifugum: A Clinically Distinct Dermatosis. CLINI-AEDV Case Series.","authors":"F Allegue, Ander Zulaica, M A Pastor-Nieto, I Ballester-Nortes, V Fernández-Tapia, M E Parera-Amer, I García-Doval","doi":"10.1016/j.ad.2025.10.006","DOIUrl":"https://doi.org/10.1016/j.ad.2025.10.006","url":null,"abstract":"<p><p>Erythema papulatum centrifugum is a rare condition marked by a centrifugally growing border dotted with small papules and a relapsing course, often worse in spring and summer. There aren't any specific diagnostic tests to confirm it. This study analyzes the clinical characteristics of seven cases, representing the largest series of non-Oriental patients to date. Our findings confirm the pruritic and seasonally relapsing nature of this condition. Lesions are typically few, primarily located on the trunk, and generally exceed 5 cm in diameter. Interestingly, in one patient, two outbreaks correlated temporally with the COVID-19 vaccine. In two other cases, the condition was linked to hematological malignancies: multiple myeloma and Hodgkin lymphoma. These observations, along with other neoplasm-associated cases reported in the literature, suggest that this entity might function as a paraneoplastic syndrome.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Claudia Matei, T Gracia-Cazaña, M Almenara Blasco, L Bernal Masferrer, Y Gilaberte
{"title":"[[Translated article]]DNA Repair Enzymes for Actinic Keratoses and Keratinocyte Cancer: A Systematic Review of Treatment and Prevention Utility.","authors":"M Claudia Matei, T Gracia-Cazaña, M Almenara Blasco, L Bernal Masferrer, Y Gilaberte","doi":"10.1016/j.ad.2025.10.001","DOIUrl":"https://doi.org/10.1016/j.ad.2025.10.001","url":null,"abstract":"<p><p>The difficulty of traditional photoprotectors in preventing actinic keratoses (AK) and keratinocyte skin cancer has led to research into new photoprotection measures. DNA repair enzymes are compounds that aim to increase the repair of DNA damaged by UV radiation and thus reduce the risk of carcinogenesis. We conducted a systematic review on the use of DNA repair enzymes in the prevention and treatment of precancerous and cancerous skin conditions in full compliance with the PRISMA guidelines, including studies published from 2000 through 2024. A total of 486 articles were identified, 20 of which 20 were included: 9 randomized clinical trials and 11 quasi-experimental trials. A total of 8 studies focused on photolyase, 6 on endonuclease, and 6 on combinations of different DNA repair enzymes. DNA repair enzymes reduce DNA damage and prevent skin cancer, especially when combined with each other as well as with traditional photoprotectors and other substances such as antioxidants. The heterogeneity of the studies limits the ability to draw definitive conclusions.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[[Translated article]]Designing and Validating a Questionnaire on Photoprotection in Children and Families (Cuestionario Fotoprotección Sulayr).","authors":"J E Muñoz Negro, A Cabrera-León, A Buendía Eisman","doi":"10.1016/j.ad.2025.10.003","DOIUrl":"https://doi.org/10.1016/j.ad.2025.10.003","url":null,"abstract":"<p><strong>Background and objective: </strong>Primary prevention is the only way to reduce the incidence rate of skin cancer. With this objective, we designed and evaluated the questionnaire's feasibility, validity, and reproducibility on photoprotective behaviors and their associated variables in the child population and their families.</p><p><strong>Material and methods: </strong>After reviewing the literature, a group of experts drafted the first questionnaire, analyzing its logical and content validity in 109 participants. A new questionnaire was obtained from this analysis, examining its internal validity through factor analysis and internal consistency (n = 98). Finally, reproducibility was determined in 32 participants who had previously answered the questionnaire.</p><p><strong>Results: </strong>Our questionnaire was easy or very easy for 75% of the study population (mean time, 12 minutes). The following 4 factors were obtained for parents (total explained variance = 61.7%): \"photoprotection of fathers and mothers\"; \"personal vulnerability to sun exposure\"; \"information received on photoprotection and healthy lifestyle habits,\" and \"sun exposure schedule\". For children, a total of 4 factors were also obtained (variance = 61.3%): \"perceived vulnerability and sun protection behavior\"; \"barriers to sun protection\"; \"other barriers\"; and \"beliefs of mothers and fathers and sunburns in their children\". On the other hand, significant changes were only observed in 5 questions. The results of each fieldwork produced improved versions of the questionnaire until its final version was obtained.</p><p><strong>Conclusion: </strong>The questionnaire was a viable, valid, and reproducible instrument to measure sun protection behavior in children and their families.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[[Translated article]]Urticaria as a Rheumatic Dermatosis in Olavide's Aphorisms.","authors":"R M Díaz Díaz, M C Martín Hervás","doi":"10.1016/j.ad.2025.10.009","DOIUrl":"https://doi.org/10.1016/j.ad.2025.10.009","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E de la Rosa-Fernández, P Llansó-Florentí, P Laynez-Roldán, S Garrido-Ríos, J González-Rodríguez, E Benítez-García, I Loizate-Sarrionandia, R Fernández-de-Misa Cabrera
{"title":"[[Translated article]]The Reality of Migration by Patera Boats: Morbidity and Dermatological Injuries.","authors":"E de la Rosa-Fernández, P Llansó-Florentí, P Laynez-Roldán, S Garrido-Ríos, J González-Rodríguez, E Benítez-García, I Loizate-Sarrionandia, R Fernández-de-Misa Cabrera","doi":"10.1016/j.ad.2025.10.007","DOIUrl":"https://doi.org/10.1016/j.ad.2025.10.007","url":null,"abstract":"<p><strong>Background and objectives: </strong>The Canary Islands (Spain) serve as the entry point to the EU for thousands of people each year, many of whom arrive by sea in small boats known as \"pateras.\" The extreme conditions of the journey often result in complex clinical presentations upon arrival.</p><p><strong>Objective: </strong>To evaluate the characteristics of patients admitted to a tertiary referral center after a journey in a patera boat.</p><p><strong>Materials and methods: </strong>We conducted a retrospective cross-sectional observational study including migrant patients after a journey in a patera boat who required admission to CHUNSC during 2023. The study evaluates the care pathway and the patients' epidemiological, clinical, and evolutionary characteristics.</p><p><strong>Results: </strong>A total of 484 patients were treated in the emergency department. A total of 93 (19.2%) required admission, the mean age was 23 years old, and 85 (91.4%) were men. The mean length of stay was 29 days. A total of 22 patients (23.6%) were admitted to the ICU for a mean 7.6 days. The most common clinical conditions upon admission were anemia (73.1%) and rhabdomyolysis (62.5%). A total of 76 patients exhibited skin lesions (81.7%), predominantly on the legs (68.4%), feet (67.1%), and buttocks and sacrum (56.6%). A total of 36 (38.7%) underwent surgery; debridement of skin necrosis was performed in 22, skin grafts in 21, and amputations in 12. A total of 35 positive cultures were obtained, with S. aureus, P. aeruginosa, and S. algae being the most frequently isolated pathogens.</p><p><strong>Conclusions: </strong>The extreme conditions of the journey in a patera lead to complex and severe clinical scenarios, with skin and soft tissue lesions often determining the prognosis. Therefore, it is essential to adequately manage these conditions and any associated comorbidities.</p>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. García-Rodríguez , M. Iglesias-Sancho , M. Martín-García
{"title":"[Translated article] A Case of Inflammatory Tinea Barbae Acquired by a Barber Shop Client","authors":"V. García-Rodríguez , M. Iglesias-Sancho , M. Martín-García","doi":"10.1016/j.ad.2025.07.011","DOIUrl":"10.1016/j.ad.2025.07.011","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 9","pages":"Pages T1015-T1017"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144681743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Rodriguez-Tamez , A. Imbernon-Moya , D. Saceda-Corralo , S. Vano-Galvan
{"title":"[Translated article] Dermatology Update on the Challenging Trichodynia","authors":"G. Rodriguez-Tamez , A. Imbernon-Moya , D. Saceda-Corralo , S. Vano-Galvan","doi":"10.1016/j.ad.2025.07.006","DOIUrl":"10.1016/j.ad.2025.07.006","url":null,"abstract":"<div><div>Trichodynia is the sensation of pain in the scalp, which, in most cases, is associated with certain types of alopecia. Despite being a term coined by Rebora back in 1996 to described patients with diffuse alopecia consistent with telogen effluvium, this symptom has currently been reported in other entities. Androgenic alopecia, scarring alopecia, alopecia areata, trichotillomania, and chemotherapy-induced alopecia are common causes of trichodynia. Similarly, its association with psychiatric comorbidities, including depression, anxiety, obsessive-compulsive disorder and somatoform disorders has been reported with a higher prevalence among women. Although its pathogenesis is still to be elucidate, some factors involved are substance P, psychiatric comorbidities and perifollicular inflammation. Clinically it exhibits pain or discomfort of the scalp, almost always in association with hair loss. The sensation of pain can occur throughout the scalp or locally in some specific areas. Diagnosis is clinical and one of exclusion. Regarding treatment, there are no specific therapies for trichodynia. However, the use of botulinum toxin A, antidepressants, neuromodulators, propranolol, topical corticosteroids, oral corticosteroids and topical cannabinoids are therapeutic alternatives that should be taken into consideration. Since treatment of trichodynia is still therapeutically challenging for dermatologists more prospective studies are needed to evaluate new therapies.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 9","pages":"Pages T990-T994"},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144681747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}