M.E. Gatica-Ortega , B. Sánchez-Albisua , D.M. Arranz-Sánchez , B. Pérez-Tato , A. Sánchez-Gilo , S. Córdoba-Guijarro , F.J. Ortiz-Frutos , N. Hernández-Cano , E. Gómez de la Fuente , M. Elosua-González , M. Bergón-Sendín , C. García-Martín , T. Sanz-Sánchez , O. Mazuela-Díez , R. Torres-Aranda , L. Vergara-de-la-Campa , S. Marinero-Escobedo , A. Alegre-Bailo , A. Garrido-Ríos , F. Tous-Romero , M.A. Pastor-Nieto
{"title":"Eritema, edema localizado y calor versus aumento del perímetro del antebrazo. ¿Ha llegado el momento de revisar las recomendaciones de consenso de la prueba de provocación del vórtice en urticaria-angioedema vibratorios?","authors":"M.E. Gatica-Ortega , B. Sánchez-Albisua , D.M. Arranz-Sánchez , B. Pérez-Tato , A. Sánchez-Gilo , S. Córdoba-Guijarro , F.J. Ortiz-Frutos , N. Hernández-Cano , E. Gómez de la Fuente , M. Elosua-González , M. Bergón-Sendín , C. García-Martín , T. Sanz-Sánchez , O. Mazuela-Díez , R. Torres-Aranda , L. Vergara-de-la-Campa , S. Marinero-Escobedo , A. Alegre-Bailo , A. Garrido-Ríos , F. Tous-Romero , M.A. Pastor-Nieto","doi":"10.1016/j.ad.2024.10.058","DOIUrl":"10.1016/j.ad.2024.10.058","url":null,"abstract":"<div><h3>Background and objective</h3><div>Diagnosis of vibratory urticaria/angioedema is established after performing the vortex provocation test. There is current consensus on measuring the forearm perimeter after running such test to define a positive response to it.</div></div><div><h3>Material and method</h3><div>We evaluated the frequency of prior symptoms following vibratory stimuli in volunteers using a questionnaire, response to the vortex provocation test in the same volunteers (increase in forearm perimeter, erythema, localized edema, heat, and pruritus), interrater reliability, and correlation between the scores obtained in the questionnaire and response to the test.</div></div><div><h3>Results</h3><div>A total of 40 volunteers participated in this survey, 17 of whom were excluded due to dermographism. A total of 59% out of 123 without dermographism responded positively to ≥1 items of the questionnaire. Localized erythema, heat or localized edema were reported in 58.5%, 38.2%, and 32.5%, respectively. A total of 73.6% of volunteers presented with itch. The mean intensity of itch was 3.44, 95%CI: 2.94-3.94). Interrater agreement was low regarding the increase in forearm circumference at 3 levels (intraclass correlation coefficient, 0.477, 95%CI: 0.253-0.634; 0.496, 95%CI: 0.280-0.647; and 0.370, 95%CI: 0.100-0.559, respectively) and optimal regarding erythema, heat and localized edema (Kappa index, 0.868; 0.756; and 0.757, respectively). A significant correlation was identified between the questionnaire score and the altered response to the test in its different variables.</div></div><div><h3>Conclusions</h3><div>We propose the following variables: erythema; localized edema; heat; and the intensity/speed of onset/duration of pruritus to define a positive response to the vortex provocation test given their ease of execution and optimal inter-observer agreement.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages 357-364"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Ortiz-Lobato , A. Imbernón-Moya , D. Saceda-Corralo , S. Vano-Galvan
{"title":"Acné queloideo de la nuca, un reto terapéutico para los dermatólogos","authors":"L. Ortiz-Lobato , A. Imbernón-Moya , D. Saceda-Corralo , S. Vano-Galvan","doi":"10.1016/j.ad.2024.08.011","DOIUrl":"10.1016/j.ad.2024.08.011","url":null,"abstract":"<div><div>Acne keloidalis nuchae (AKN) is a chronic inflammatory dermatosis of the scalp that causes scarring alopecia. The etiology of AKN has been associated with an immune response vs. follicular antigens. AKN is characterized by fibrotic papules and plaques that can converge in tumor-like lesions; subclinical disease has been reported in perilesional areas, which could impact its development. Early diagnosis and treatment are essential to reduce morbidity and preserve and minimize healing. Various treatments have been established including optimal medical therapy, surgical excision, and light sources. An updated description of treatments (algorithm included) used for AKN is suggested based on the clinical lesions.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages 394-402"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Peris-Espino , M. Munera-Campos , P. Chicharro , A. González Quesada , Á. Flórez Menéndez , P. de la Cueva Dobao , A.M. Giménez Arnau , Y. Gilaberte Calzada , M. Rodríguez Serna , T. Montero-Vilchez , J.F. Silvestre Salvador , R. Ruiz-Villaverde , M. Elosua-González , E. del Alcázar-Viladomiu , J. Sánchez-Pérez , G. Carretero Hernández , A. Batalla , H.J. Suh Oh , C. Couselo-Rodríguez , C. Mauleón Fernández , J.M. Carrascosa Carrillo
{"title":"Perfil clínico, epidemiológico y respuesta al tratamiento, en función de la comorbilidad atópica asociada en la dermatitis atópica. Experiencia del registro BIOBADATOP","authors":"V. Peris-Espino , M. Munera-Campos , P. Chicharro , A. González Quesada , Á. Flórez Menéndez , P. de la Cueva Dobao , A.M. Giménez Arnau , Y. Gilaberte Calzada , M. Rodríguez Serna , T. Montero-Vilchez , J.F. Silvestre Salvador , R. Ruiz-Villaverde , M. Elosua-González , E. del Alcázar-Viladomiu , J. Sánchez-Pérez , G. Carretero Hernández , A. Batalla , H.J. Suh Oh , C. Couselo-Rodríguez , C. Mauleón Fernández , J.M. Carrascosa Carrillo","doi":"10.1016/j.ad.2024.09.019","DOIUrl":"10.1016/j.ad.2024.09.019","url":null,"abstract":"<div><h3>Background</h3><div>Despite advances made in treatments for atopic dermatitis (AD), information on its impact and interaction with atopic comorbidities, such as asthma, rhinoconjunctivitis, and ocular disease is limited. This study aims to assess the clinical-epidemiological characteristics of patients with AD—treatment response included—while taking into consideration atopic comorbidities like these.</div></div><div><h3>Materials and methods</h3><div>Data were analyzed from the multicenter BIOBADATOP registry (a prospective cohort of AD patients initiating systemic treatment). We conducted a descriptive analysis of the main characteristics collected in the registry in relation to atopic comorbidity.</div></div><div><h3>Results</h3><div>We included a total of 509 patients, mostly adults (81.9%) with severe AD (73.7%). Patients with personal atopic comorbidity (64%) more frequently exhibited flexural dermatitis (89.7% vs 81.5%), a higher mean of previous systemic treatments (1.6 vs. 1.3), and higher baseline values on the POEM scale (19.6 vs. 17.9). Patients with familial atopic comorbidity (40.7%) had a higher incidence of pediatric/adolescent patients (24.2% vs. 13.9%) and a history of allergic rhinoconjunctivitis (61.1% vs. 47.1%). No differences regarding treatment response were observed at the 6- and 12-month follow-ups based on the presence or absence of atopic comorbidities.</div></div><div><h3>Conclusions</h3><div>Results suggest that a history of atopic comorbidity is associated with an early onset and persistent course of AD. Although no differences were reported in the short-term treatment response, further follow-up is required to better understand the impact of comorbidities on AD.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages 337-348"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Al-wattar-Ceballos, L. Martínez-Montalvo, M. Montero-García
{"title":"[Translated article] RF – An Update on the Pharmacologic Management of Androgenetic Alopecia in Transgender Patients","authors":"O. Al-wattar-Ceballos, L. Martínez-Montalvo, M. Montero-García","doi":"10.1016/j.ad.2025.02.004","DOIUrl":"10.1016/j.ad.2025.02.004","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages T421-T422"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Requena, E. Sánchez-Romero, E. Nagore, O. Sanmartín
{"title":"[Translated article] Paraneoplastic Dermatomyositis: A 25-patient Series From a Cancer Center","authors":"C. Requena, E. Sánchez-Romero, E. Nagore, O. Sanmartín","doi":"10.1016/j.ad.2025.02.012","DOIUrl":"10.1016/j.ad.2025.02.012","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages T444-T448"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Fabregat-Pratdepadua, V. Mora Fernández, J. Verdaguer-Faja, J. Bassas Vila
{"title":"[Translated article] Perianal Comedones: A Variant of Hidradenitis Suppurativa or an Isolated Entity? Five-Case Report","authors":"M. Fabregat-Pratdepadua, V. Mora Fernández, J. Verdaguer-Faja, J. Bassas Vila","doi":"10.1016/j.ad.2025.02.005","DOIUrl":"10.1016/j.ad.2025.02.005","url":null,"abstract":"<div><div>Although comedones are a prevalent entity in multiple skin diseases, their perianal location as a cluster is a rare finding. We describe 5 patients with grouped perianal comedones who developed the lesions in adulthood and were treatment-naïve in the perianal area. Four of them had had inflammatory lesions in armpits and groins. In 2, the anatomopathological examination revealed the presence of follicular infundibulum dilatation, cystification, and fibrotic and inflammatory changes in the underlying dermis—findings consistent with hidradenitis suppurativa—which is why we wonder whether grouped perianal comedones are a mild form of hidradenitis suppurativa or an isolated entity.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":"116 4","pages":"Pages T403-T406"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}