Addictive behaviors最新文献

{"title":"Race and ethnicity differences in the association between the sensory experience and appeal of e-cigarette products: A pooled analysis of four within-subject experiments","authors":"Tyler B. Mason ,&nbsp;Dae-Hee Han ,&nbsp;Melissa Wong ,&nbsp;Dayoung Bae ,&nbsp;Alyssa F. Harlow ,&nbsp;Adam M. Leventhal","doi":"10.1016/j.addbeh.2025.108447","DOIUrl":"10.1016/j.addbeh.2025.108447","url":null,"abstract":"<div><div>We pooled data from four product appeal testing experiments to examine whether associations of sensory attribute ratings (i.e., sweet, smooth, bitter, and harsh) of e-cigarettes with product appeal are moderated by race/ethnicity. Non-Hispanic White (<em>n</em> = 174), Black (<em>n</em> = 99), Asian (<em>n</em> = 34), Hispanic (<em>n</em> = 29), another race (<em>n</em> = 13), and multiracial (<em>n</em> = 56) adult tobacco product users completed product appeal testing. Participants self-administrated standardized doses of 8–40 different e-cigarette products (depending on the experiment) and rated the products’ sensory attributes and appeal. Multilevel models examined race/ethnicity as a moderator of the association of sensory attributes with appeal, using analyses partitioning between- and within-subjects variance. Product-specific (within-subjects) variance in sweetness was associated with enhanced e-cigarette appeal less strongly for Black vs. non-Hispanic White participants. Product-specific smoothness enhanced e-cigarette appeal more strongly for multiracial vs. non-Hispanic White participants. Product-specific bitterness reduced e-cigarette appeal more strongly for Hispanic vs. non-Hispanic White participants. Product-specific harshness reduced e-cigarette appeal and product-specific smoothness enhanced appeal less for Asian compared to non-Hispanic White participants. Regulatory restrictions on additives that suppress the harsh or bitter qualities of e-cigarettes may deter Hispanic adults from e-cigarettes but may be less likely to deter Asian adults. Black adults perceived appeal was less related to sweetness and thus may be more responsive to regulations outside of bans on sweet additives.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108447"},"PeriodicalIF":3.6,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144756845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of adolescent cannabis use and social context predicting problematic use: A decision tree analysis","authors":"Katelyn Battista ,&nbsp;Slim Haddad ,&nbsp;Scott T. Leatherdale ,&nbsp;Richard Bélanger","doi":"10.1016/j.addbeh.2025.108445","DOIUrl":"10.1016/j.addbeh.2025.108445","url":null,"abstract":"<div><div>Identifying characteristics of adolescent cannabis use and the surrounding social context that may predict problematic use is important for delivering harm-reduction approaches in both clinical and public health settings. We used a decision tree analysis to identify combinations of various use characteristics (e.g., frequency, mode, duration, initiation age, polysubstance use) and social context risk factors (e.g., peer and household use, solitary use, ease of access) characterizing the highest risk groups for three indicators of problematic use (unsuccessful quit attempt, excessive use, feeling addicted). We analyzed data from 8,915 cannabis ever-users from a large sample of secondary school students (mean age 15.5) in Québec, Canada, who completed the COMPASS survey. Using cannabis at least 2–4 times per month was the most important predictor of problematic use and independently characterized the highest risk groups. Initiating use before age 14 and engaging in solitary use also predicted increased problematic use risk among adolescents whose sustained past-year use did not meet the 2–4 times per month threshold. No sociodemographic differentiation emerged among high-risk groups. When screening for risky cannabis use or promoting safer cannabis behaviours among adolescents, health care providers and public health groups should consider factors with the greatest potential to influence detrimental trajectories among this age group.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108445"},"PeriodicalIF":3.6,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of bias-based bullying in regular cannabis use among adolescents","authors":"Amy L. Gower ,&nbsp;Ryan J. Watson ,&nbsp;Lauren Love Pieczykolan ,&nbsp;Marla E. Eisenberg","doi":"10.1016/j.addbeh.2025.108441","DOIUrl":"10.1016/j.addbeh.2025.108441","url":null,"abstract":"<div><div>Studies show bias-based bullying and harassment compromise health for youth with minoritized identities, and heavy/regular use of cannabis has implications for adolescent brain development. We examined how regular cannabis use varied by experiences of bullying based on sexual orientation, gender identity, and expression (SOGIE) or race and ethnicity, and social positions. Data came from 8th, 9th, and 11th graders completing the 2022 Minnesota Student Survey (N = 82,933). Students reported past 30 day cannabis use (3–5 times or more versus fewer/none), social positions (i.e., sexual, gender, racial, and ethnic identities, grade, access to resources), and race- and SOGIE-based bullying in the past 30 days (any versus none). Exhaustive Chi-square automatic interaction detection identified combinations of five social positions and bias-based bullying associated with the highest prevalences of regular cannabis use for each grade. Results indicated that across grades, cannabis use was 50–68 % lower among youth in social positions with the highest prevalence of frequent cannabis use when they were not the targets of bias-based bullying compared to youth with the same social positions who were targets of bias. For example, 18 % of 8th graders who had low access to resources; identified as American Indian, Alaska Native, or multiracial; and who experienced SOGIE-based bullying engaged in regular cannabis use, compared to 6.8 % prevalence for youth with the same identities who did not report bias-based bullying. Future research that examines bias-based bullying as a potential mechanism in adolescent cannabis use is warranted, particularly among youth with multiple minoritized identities.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108441"},"PeriodicalIF":3.6,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the complexity of associations between problematic internet use, anxiety, and somatic symptoms in Chinese youth: a network perspective","authors":"Tingting Fang ,&nbsp;Feng Zhuo ,&nbsp;Xinran Xie ,&nbsp;Ying Yang ,&nbsp;Linghua Kong","doi":"10.1016/j.addbeh.2025.108438","DOIUrl":"10.1016/j.addbeh.2025.108438","url":null,"abstract":"<div><h3>Background</h3><div>Problematic Internet Use (PIU) is increasingly recognized as a significant public health concern among adolescents, often leading to anxiety symptoms and somatic symptoms. However, the underlying interrelationships between these symptom domains remain insufficiently understood, particularly at the symptom level.</div></div><div><h3>Methods</h3><div>This study applied network analysis to investigate the complexity of associations among PIU, anxiety, and somatic symptoms in a large, cross-sectional sample of 5221 adolescents aged 10–19 years from Shandong Province, China. Validated self-report instruments were used to assess PIU (IAT), anxiety (MASC), and somatic complaints (PHQ-13). Gaussian Graphical Models were constructed to identify central and bridge symptoms across the network, and sex differences were explored using the Network Comparison Test.</div></div><div><h3>Results</h3><div>The prevalence of PIU was 11.91%. Network analysis revealed dense interconnections among symptoms, with 64.7% of edges being non-zero. “Physical symptoms” of anxiety (MASC1) emerged as the most central and bridging symptom across the network, demonstrating the highest node strength and expected influence. The strongest edge linking PIU, anxiety, and somatic symptoms was between “physical symptoms” and “cannot breathe”. Although no significant gender differences were found in global network strength, the structure of symptom networks differed significantly between males and females. In males, the strongest bridge linked “time management &amp; performance” with “sleep problems”, whereas in females, “withdrawal &amp; social problems” was strongly linked to “indigestion symptoms”.</div></div><div><h3>Conclusions</h3><div>This study is the first to employ network analysis to map symptom-level associations between PIU, anxiety, and somatic symptoms in adolescents. The findings underscore the central role of anxiety-related physical symptoms in the network and highlight gender-specific symptom bridges. These insights offer novel directions for targeted interventions, emphasizing the need for symptom-focused and gender-sensitive treatment strategies for adolescents affected by PIU.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108438"},"PeriodicalIF":3.6,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impulsive Decision Reduction Training (IDRT) reduces binge drinking and increases future orientation in young adult binge drinkers","authors":"Peter R. Finn ,&nbsp;Michael P. Smoker ,&nbsp;Zachary W. Adams ,&nbsp;Brigid R. Marriott ,&nbsp;Eli J. Farmer ,&nbsp;Leslie A. Hulvershorn","doi":"10.1016/j.addbeh.2025.108443","DOIUrl":"10.1016/j.addbeh.2025.108443","url":null,"abstract":"<div><div>This paper introduces Impulsive Decision Reduction Training (IDRT) as a “proof of concept” in terms of its feasibility and preliminary outcome associations. IDRT is a novel, manualized, 8-week intervention designed to reduce impulsive and risky decisions regarding alcohol consumption and reduce excessive drinking. We conducted a pilot study of IDRT in young adult college students who binge drink, comparing IDRT with a waitlist control condition. Twenty-five participants (13 women, 12 men) completed the 8-week IDRT intervention and were compared with 20 (6 women and 14 men) who completed the assessments in the waitlist control group. IDRT was well-received (rated as very helpful), with all sessions attended, and only one IDRT participant dropping out after 3 sessions. Three waitlist control participants did not show up for the additional assessments after their initial baseline assessment. IDRT was associated with significant and large increases in future orientation and the consideration of the consequences of decisions (ps &lt; 0.001). IDRT also associated with significant but modest reductions in the frequency of drinking (p &lt; 0.05) and the maximum number of drinks consumed (p &lt; 0.05), but not in the average quantity of alcohol consumed in an occasion or delay discounting rates, compared to a waitlist control condition. IDRT shows some initial promise as an intervention targeting reductions in impulsive and risky drinking decisions and reducing excessive drinking. Formal clinical trials should be conducted to more comprehensively assess the effectiveness of IDRT in reducing excessive drinking.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108443"},"PeriodicalIF":3.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective associations between smoking abstinence and anhedonia among people who seek smoking cessation treatment","authors":"Elizabeth Moss-Alonso ,&nbsp;Rubén Rodríguez-Cano ,&nbsp;Carmela Martínez-Vispo ,&nbsp;Ana López-Durán ,&nbsp;Elisardo Becoña","doi":"10.1016/j.addbeh.2025.108439","DOIUrl":"10.1016/j.addbeh.2025.108439","url":null,"abstract":"<div><h3>Introduction</h3><div>Depression has been broadly studied in association with tobacco smoking. However, little is known about the prospective association between anhedonia, one of the core symptoms of depression, and smoking outcomes after smoking cessation treatment. The goal of this study was to examine the bidirectional and longitudinal relation between anhedonia and smoking abstinence after smoking cessation intervention and up to a 12-month follow-up.</div></div><div><h3>Methods</h3><div>The sample was composed of 685 participants (Mage = 45.51; 62 % female) that were enrolled in three cognitive-behavioural smoking cessation interventions. Anhedonia and smoking abstinence were measured at post-treatment, and at 3-, 6- and 12-month follow-ups. The bidirectional and longitudinal association was analysed applying a Random Intercept Cross-Lagged Panel Model (RI-CLPM), and results were controlled for the effects of sex and differing studies.</div></div><div><h3>Results</h3><div>The RI-CLPM showed that smoking abstinence in one timepoint predicted lower anhedonia at the following timepoint for each assessment. Although greater anhedonia was related to lower smoking abstinence crossectionally at post-treatment, 6- and 12-month follow-ups, precedent anhedonia did not predict consequent smoking abstinence at any follow-up. The results were consistent when controlling potential confounding variables.</div></div><div><h3>Conclusions</h3><div>The bidirectional analysis indicated that smoking abstinence predicted lower anhedonia after a smoking cessation intervention during the course of 12 months, but anhedonia did not significantly predict smoking abstinence at any consequent timepoint. Findings have relevant implications as may serve to motivate healthcare professionals to apply tailored smoking cessation interventions, and people who smoke to quit due to the potential impact on mood.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108439"},"PeriodicalIF":3.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tobacco and cannabis use among pregnant women with prenatal opioid use","authors":"E. Melinda Mahabee-Gittens ,&nbsp;Nicole Mack ,&nbsp;Carla M. Bann ,&nbsp;Jamie E. Newman ,&nbsp;Junfang Zhao ,&nbsp;Kenneth D.R. Setchell ,&nbsp;Lara Stone ,&nbsp;Namasivayam Ambalavanan ,&nbsp;Myriam Peralta-Carcelen ,&nbsp;Sara B. DeMauro ,&nbsp;Scott A. Lorch ,&nbsp;Deanne E. Wilson-Costello ,&nbsp;Brenda B. Poindexter ,&nbsp;Catherine Limperopoulos ,&nbsp;Jonathan M. Davis ,&nbsp;Stephanie L. Merhar","doi":"10.1016/j.addbeh.2025.108442","DOIUrl":"10.1016/j.addbeh.2025.108442","url":null,"abstract":"<div><h3>Background</h3><div>There is a paucity of information on tobacco and cannabis use patterns in pregnant women who use opioids. Our objective was to examine sociodemographic, tobacco, and cannabis use patterns during pregnancy among pregnant women with opioid use.</div></div><div><h3>Methods</h3><div>We recruited 206 pregnant women with biochemically verified opioid use during pregnancy, of whom 98 self-reported taking only medications for opioid use disorder (MOUD) and 108 reported taking other opioids during pregnancy. We examined sociodemographic characteristics and self-report of tobacco and cannabis use overall and by trimester. Chi-square and t-tests were used to assess differences between the MOUD-only vs other opioids groups. Logistic regression models were used to examine differences in factors associated with tobacco and cannabis use.</div></div><div><h3>Results</h3><div>Mean (SD) age was 30.7 years (4.6); 81.9 % were non-Hispanic White, and 92.6 % had public insurance. Of the 91 women taking MOUD only and completing the substance use self-report, 50 (54.9 %) reported tobacco use only, 3 (3.3 %) reported cannabis use only, and 24 (26.4 %) reported both tobacco and cannabis use. Tobacco and cannabis use was similar for women taking other opioids (p = 0.98). Adjusted odds ratios indicated that there was consistent use of all tobacco products (p = 0.28) including e-cigarette products (p = 0.18) throughout all 3 trimesters of pregnancy. There was decreased use of cannabis over the course of pregnancy with 29.8 % using cannabis during the first trimester and 16.5 % during the last trimester (p = 0.0003).</div></div><div><h3>Conclusions</h3><div>While we observed no differences in tobacco and cannabis use between those taking MOUD only versus other opioids, we observed high rates of tobacco and cannabis use among pregnant women with opioid use. These findings underscore the need for tobacco and cannabis use education and cessation interventions throughout pregnancy for those with OUD.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108442"},"PeriodicalIF":3.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The long and winding road to treatment for problem gambling: from problem awareness to treatment helpfulness","authors":"Youssef Allami ,&nbsp;Robert J. Williams ,&nbsp;Darren R. Christensen ,&nbsp;Carrie A. Shaw ,&nbsp;Daniel S. McGrath ,&nbsp;Rhys M.G. Stevens ,&nbsp;Fiona Nicoll ,&nbsp;Hyoun S. Kim ,&nbsp;David C. Hodgins","doi":"10.1016/j.addbeh.2025.108440","DOIUrl":"10.1016/j.addbeh.2025.108440","url":null,"abstract":"<div><div>Only a minority of individuals with problem gambling (PG) seek specialized treatment, often doing so only after experiencing significant problems for many years. To better understand the trigger points and pathways that lead individuals to treatment, this mixed-methods study recruited 65 Canadian adults currently receiving treatment for PG. Using a Timeline Follow-Back methodology, participants recalled key trigger points that led them to recognize their gambling problems and ultimately seek professional treatment. Their treatment histories for substance use, mental health, and gambling problems were also assessed, including the ages at which these treatments occurred. Additionally, participants responded to open-ended questions about how various gambling-specific treatment modalities were helpful to them. The delay between recognizing gambling problems and seeking help was about four years. Participants tended to first seek help from friends or family, whereas religious counselling generally came last. A content analysis of responses identified key categories related to trigger points, initial attempts to limit gambling, and the perceived benefits of specialized treatment. Financial problems were identified as both the most frequent triggers for problem recognition and for initiating change. Among participants who had previously sought specialized help for substance use problems, gambling problems emerged concurrently to these treatment episodes. These findings highlight the interconnectedness of mental health, substance use, and PG and provide valuable insights into how individuals with gambling problems can be encouraged to seek help that aligns with their specific needs. Public health implications include improving support access and screening for gambling in mental health and addiction services.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108440"},"PeriodicalIF":3.7,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring gambling harm awareness and its relationship with problem gambling severity: A nationally representative study of UK gamblers","authors":"Christy Milia ,&nbsp;Ian P. Albery ,&nbsp;Marcantonio Spada ,&nbsp;Briony Gunstone ,&nbsp;Antony C. Moss","doi":"10.1016/j.addbeh.2025.108435","DOIUrl":"10.1016/j.addbeh.2025.108435","url":null,"abstract":"<div><div>From a public health perspective, raising awareness of gambling-related harms may activate a sense of personal threat that can encourage positive behaviour change and reduce experienced harm. This study sought to determine existing levels of gambling harm awareness, both in total and by specific harm types, across a nationally representative UK sample of 10,157 adult gamblers (4,951 female). It also explored the relationship between gambling harm awareness and problem gambling severity, after controlling for various demographic variables and gambling motives. Participants were recruited via an online panel survey and provided self-reports of past-year gambling participation, motives, problem gambling severity, and awareness of different types of harms. The harm awareness measure used a prompted vs. unprompted cueing methodology and framed harms as either betting- or gambling-related based on a previously reported semantic distinction. Results showed that prompting significantly increased the number of harms reported, while harm framing did not. Regardless of condition, participants reported greater awareness of resource harms (e.g., financial difficulties) compared to health and relationship harms, and a quarter of the sample did not report any type of betting/gambling harm. Based on the results of a hierarchical linear regression, gambling harm awareness explained significant variability in problem gambling severity scores. Increased gambling severity scores were associated with greater awareness of health harms and decreased gambling severity scores were related to greater awareness of resource and relationship harms. These findings raise concerns about the overall effectiveness of current public health efforts in increasing harm awareness and suggest the need to broaden their focus to support individuals of varying risk levels in recognising and addressing a wider range of gambling-related harms.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108435"},"PeriodicalIF":3.7,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diversity in opioid-related stigma interventions: A systematic review","authors":"Rachel Girard ,&nbsp;Devin C. Tomlinson ,&nbsp;Chavez R. Rodriguez ,&nbsp;Kyersten Frabizio ,&nbsp;Lara Coughlin ,&nbsp;Lewei Allison Lin ,&nbsp;Nichea S. Spillane","doi":"10.1016/j.addbeh.2025.108432","DOIUrl":"10.1016/j.addbeh.2025.108432","url":null,"abstract":"<div><h3>Background</h3><div>Opioid use disorder (OUD) is a highly stigmatized, debilitating condition affecting millions in the U.S., with stigma posing a major barrier to treatment engagement, retention, and outcomes. Disparities in OUD and opioid-involved overdoses disproportionately impact marginalized communities, underscoring the urgent need for culturally-informed stigma reduction interventions that address intersecting forms of discrimination and health inequities. This review examined interventions targeting OUD-related stigma, focusing on the diversity and cultural relevance of these initiatives.</div></div><div><h3>Methods</h3><div>Following PRISMA guidelines, we reviewed articles published through May 2025 that described interventions addressing opioid/OUD-related stigma.</div></div><div><h3>Results</h3><div>Most studies targeted provider or public stigma and involved students, healthcare professionals, or justice-involved individuals. However, demographic representation was inconsistent, with limited attention to race, ethnicity, gender identity, or sexual orientation. Sixty-eight percent of studies incorporated cultural considerations, most commonly through the inclusion of individuals with lived OUD experience.</div></div><div><h3>Conclusions</h3><div>This is the first review to specifically examine cultural factors in interventions addressing opioid-related stigma. While notable progress has been made, gaps remain—particularly in the consistent collection of sociodemographic data and in the design of tailored interventions that address intersectional stigma and meaningfully engage marginalized communities. To address these gaps, future efforts should adopt inclusive recruitment strategies, apply intersectional frameworks, and collaborate with communities to integrate lived experiences. These culturally informed approaches, defined here as strategies that are responsive to the cultural identities, values, and social contexts of affected populations, could support the development and evaluation of stigma reduction interventions that better serve diverse populations.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108432"},"PeriodicalIF":3.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}