Moscow University Chemistry Bulletin最新文献_第3页

Structural Classes of Lattice Partitions of a Plane into Dodecominos 平面点阵分割的结构类

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S0027131425700129

K. G. Seravkin, K. A. Potekhin, A. M. Banaru

引用次数: 0

Carotenoid Astaxanthin Effect on Phospholipid Peroxidation Induced by Ferrous Ions 类胡萝卜素虾青素对铁离子诱导磷脂过氧化的影响

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S0027131425700166

A. G. Dudnik, N. Yu. Lotosh, E. A. Kulikov, A. V. Levanov, A. A. Selishcheva

{"title":"Carotenoid Astaxanthin Effect on Phospholipid Peroxidation Induced by Ferrous Ions","authors":"A. G. Dudnik, N. Yu. Lotosh, E. A. Kulikov, A. V. Levanov, A. A. Selishcheva","doi":"10.3103/S0027131425700166","DOIUrl":"10.3103/S0027131425700166","url":null,"abstract":"Activation of the process of phospholipid peroxidation in the presence of divalent iron ions can cause cell death. It is generally accepted that the addition of different types of antioxidants should lead to the inhibition of this process. The aim of this paper is to study the effect of the carotenoid astaxanthin as an antioxidant on phospholipid peroxidation induced by iron ions in the composition of nano- and microemulsions in which the particle sizes are about 700–900 and 110–130 nm, respectively. It is shown that astaxanthin in the absence of iron ions reduced the malondialdehyde content in micro- and nanoemulsions. However, in the presence of iron ions, in the case of microemulsions, astaxanthin at a concentration of 30 μM reduces the content of malondialdehyde, and at a concentration of 5 μM, it has a prooxidant effect. Astaxanthin has no effect in the composition of the nanoemulsions. It is found that in the presence of iron ions, astaxanthin is bleached, undergoing degradation and oxidation. In the case of nanoemulsions, the bleaching rate constant is significantly higher than in microemulsions: 18.5 × 103 M–1 min–1 and 2.1 × 103 M–1 min–1, respectively. Thus, in the composition of nanoemulsions, astaxanthin quickly degrades and oxidizes (within 30 min), and in the composition of microemulsions, this process is slower. Possible mechanisms of interaction of astaxanthin with iron ions are discussed, which include both the formation of astaxanthin radicals and a nonradical complex with iron ions.","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"80 3","pages":"176 - 184"},"PeriodicalIF":0.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145166273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Digital Colorimetry: Selection of Conditions to Measure an Analytical Signal 数字比色法：测量分析信号的条件选择

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S0027131425700105

V. S. Milkina, O. V. Monogarova, K. V. Oskolok, A. V. Garmay

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In Vitro Effects of Some Plant Extracts and Chemical Substances (Acids, Metal Salts, and Vitamins) on Sorbitol Dehydrogenase Activity 一些植物提取物和化学物质（酸、金属盐和维生素）对山梨糖醇脱氢酶活性的体外影响

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S0027131425700191

Neriman Karahan, Eda Dagsuyu, Refiye Yanardag

{"title":"In Vitro Effects of Some Plant Extracts and Chemical Substances (Acids, Metal Salts, and Vitamins) on Sorbitol Dehydrogenase Activity","authors":"Neriman Karahan, Eda Dagsuyu, Refiye Yanardag","doi":"10.3103/S0027131425700191","DOIUrl":"10.3103/S0027131425700191","url":null,"abstract":"Sorbitol dehydrogenase (SDH) is a metalloenzyme and belongs to the dehydrogenase/reductase enzyme family. It catalyzes the conversion of sorbitol, a sugar alcohol derived from glucose, to fructose in a reversible reaction. This reaction is part of the sorbitol pathway, which is an alternative pathway for glucose metabolism. SDH is found in various tissues throughout the body, including the liver, kidneys, and eyes. Dysregulation of the sorbitol pathway has been implicated in various diseases, including diabetic complications. In conditions such as diabetes mellitus, elevated blood glucose levels can lead to increased sorbitol production, accumulating in tissues and contributing to tissue damage, particularly in the eyes, nerves, and kidneys. Inhibitors of SDH may hold potential for the treatment of diabetic complications and other conditions associated with aberrant sorbitol metabolism. In our study, the inhibitory effects of various plant aqueous extracts and chemicals (acids, metal salts, and vitamins) on SDH activities were investigated in vitro. Among the plant extracts we used, it was found that red pepper inhibited the SDH enzyme to the highest extent. It was also observed that chlorogenic acid from acids, manganese(II) sulfate from metal salts, and vitamin B2 from vitamins significantly inhibited the SDH enzyme. Overall, SDH plays a significant role in the context of diabetes and its complications. So, the plant extracts and chemical substances showing high levels of SDH inhibition may prevent complications resulting from diabetes and could be used to alleviate the side effects of the disease.","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"80 3","pages":"193 - 203"},"PeriodicalIF":0.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145165838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Colorimetric Determination of Ammonium in Soil Samples 土壤样品中铵的比色测定

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S0027131425700117

A. V. Garmay, K. V. Oskolok, O. V. Monogarova, S. N. Chichulin

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Selenohydantoin Self-Assembled Monolayers on the Surface of Gold 金表面硒醛酸钠自组装单层膜

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S0027131425700142

V. D. Dolzhikova, Yu. G. Bogdanova, E. K. Beloglazkina

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Spectrophotometric Method for the Quantitative Determination of Total Anthocyanins in Acerola (Malpighia emarginata) Raw Material 分光光度法定量测定针叶树原料中总花青素含量

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S002713142570018X

E. E. Kurdyukov, O. P. Rodina, A. V. Mitishev, A. S. Fednina, A. Yu. Nemova

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Cationic Antimicrobial Peptidomimetics Based in L-Lysine and Aliphatic Derivatives of Enantiomers of Valine and Leucine 基于l -赖氨酸和缬氨酸和亮氨酸对映异构体脂肪衍生物的阳离子抗菌类肽

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Moscow University Chemistry Bulletin Pub Date : 2025-06-16 DOI: 10.3103/S0027131425700154

Yu. V. Kozlova, A. V. Knyazeva, U. A. Budanova, Yu. L. Sebyakin

{"title":"Cationic Antimicrobial Peptidomimetics Based in L-Lysine and Aliphatic Derivatives of Enantiomers of Valine and Leucine","authors":"Yu. V. Kozlova, A. V. Knyazeva, U. A. Budanova, Yu. L. Sebyakin","doi":"10.3103/S0027131425700154","DOIUrl":"10.3103/S0027131425700154","url":null,"abstract":"It is established that several pathogenic bacterial strains, such as ESCAPE, can easily acquire resistance to traditional antibiotics. This leads to the emergence of multidrug resistance without currently available effective treatment of the diseases they cause. Antimicrobial resistance is becoming a global problem and requires a search for new approaches to solve this problem. Research in recent decades has focused on the use of antimicrobial peptides (AMPs) and low-molecular peptidomimetics as compounds with promising potential activity against pathogenic bacteria. This study presents data on the prospects for further development and use of lipodipeptides based on L-lysine derivatives and optical isomers of esters of aliphatic amino acids valine and leucine. It is shown that the synthesized cationic amphiphiles exhibit a high level of activity against test gram-positive and gram-negative bacteria. No significant differences in the efficiency of optical isomers of the two amino acid derivatives are found. The determining factor in the activity of the samples is the slightly higher level of hydrophobicity of the cationic lipodipeptides LysValCn and LysLeuCn with a difference in the length of the hydrocarbon radicals of the obtained compounds.","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"80 3","pages":"169 - 175"},"PeriodicalIF":0.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145166272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Surface Modified Nanozymes: Production, Properties, and Analytical Application

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Moscow University Chemistry Bulletin Pub Date : 2025-05-13 DOI: 10.3103/S0027131425700014

V. G. Panferov, O. D. Hendrickson, A. V. Zherdev, B. B. Dzantiev

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Calculation and Properties of a 3D-Molecular Shannon Entropy Using Interatomic Distance Histograms

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Moscow University Chemistry Bulletin Pub Date : 2025-05-13 DOI: 10.3103/S0027131425700051

V. Y. Grigorev, L. D. Grigoreva, O. V. Tinkov

引用次数: 0