Moscow University Chemistry Bulletin最新文献_第10页

Post-Translational Modifications of the Sulfhydryl Group of the Cysteine Residue of Glyceraldehyde-3-phosphate Dehydrogenase 甘油醛-3-磷酸脱氢酶半胱氨酸残基巯基的翻译后修饰

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-06-04 DOI: 10.3103/S0027131424700056

V. I. Muronetz, M. V. Medvedeva, E. V. Schmalhausen

{"title":"Post-Translational Modifications of the Sulfhydryl Group of the Cysteine Residue of Glyceraldehyde-3-phosphate Dehydrogenase","authors":"V. I. Muronetz, M. V. Medvedeva, E. V. Schmalhausen","doi":"10.3103/S0027131424700056","DOIUrl":"10.3103/S0027131424700056","url":null,"abstract":"The main types of oxidative post-translational modifications of the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDН) targeting the sulfhydryl group of the catalytic cysteine residue Cys152 are reviewed. The highly reactive sulfhydryl group of Cys152 in the active center of GAPDH undergoes oxidation and S-nitrosylation, leading to inactivation and destabilization of the enzyme. Upon reversible oxidation of the sulfhydryl group to form cysteine-sulfenic acid, the enzyme loses dehydrogenase activity, but gains the ability to catalyze the acyl-phosphatase reaction. Hydrolysis of the product of the dehydrogenase reaction, 1,3-diphosphoglycerate, under the action of oxidized GAPDH leads to uncoupling of oxidation and phosphorylation at this stage of glycolysis. The action of nitric oxide results in S-nitrosylation of Cys152 in GAPDH with the subsequent formation of cysteine-sulfenic acid due to hydrolysis of the S-NO-group. Data are presented on the relationship between S-nitrosylation, oxidation and S-glutathionylation of Cys152 in GAPDH. The role of post-translational modifications of the sulfhydryl group of the catalytic cysteine residue in the regulation of enzyme activity, as well as the mechanisms ensuring the reversibility of such modifications are discussed.","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"79 2","pages":"115 - 120"},"PeriodicalIF":0.7,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141548874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous Determination of Chlorhexidine, p-Chloroaniline, Triclosan, Dibutyl Phthalate, and Ionol in an Antibacterial Liquid by HPLC with Spectrophotometric Detection 利用高效液相色谱法和分光光度法同时测定抗菌液中的洗必泰、对氯苯胺、三氯生、邻苯二甲酸二丁酯和离子醇

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010073

A. V. Pirogov, S. M. Staroverov

引用次数: 0

Solubility Study of Amlodipine Besylate in Ethylene Glycol + 2-Propanol Mixtures at Different Temperatures 不同温度下苯磺酸氨氯地平在乙二醇和 2-丙醇混合物中的溶解度研究

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010048

Homa Rezaei, Kader Poturcu, Abolghasem Jouyban, Hongkun Zhao, Elaheh Rahimpour

引用次数: 0

Comparative Analysis of the Capabilities of Spectral Methods in Studying the Internal Rotation of Compounds of the Benzoic Series 光谱法研究苯甲酸系列化合物内旋能力的比较分析

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S002713142401005X

L. A. Koroleva, A. V. Koroleva

{"title":"Comparative Analysis of the Capabilities of Spectral Methods in Studying the Internal Rotation of Compounds of the Benzoic Series","authors":"L. A. Koroleva, A. V. Koroleva","doi":"10.3103/S002713142401005X","DOIUrl":"10.3103/S002713142401005X","url":null,"abstract":"In this review the methods used to study internal rotation (IR) in the ground (S0) and excited (S1) electronic states for compounds of the benzoic series C6H5–COR, where R = H, F, and CI, are compared. In the (S0) electronic state, differences in the values of (0–v) transitions of the torsional vibration for the studied compounds are revealed in the methods of analysis of the vibrational structure of the n–π* transition of high-resolution UV absorption spectra and Fourier-transform IR spectra. The reasons for such differences are established. In the excited (S1) state for benzaldehyde, the method of analyzing the vibrational structure of the n–π* transition of high-resolution UV absorption spectra and the method of analyzing the excitation spectra of the sensitized phosphorescence of this compound in a cooled jet are compared. It is concluded that the method of analyzing the vibrational structure of the n–π* transition of the high-resolution UV absorption spectra of vapors of the investigated compounds is more reliable and accurate when studying the IR in both electronic states.","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"79 1","pages":"1 - 13"},"PeriodicalIF":0.7,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140576169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modelling Silver Cluster Complexes with the Antibacterial Medication Dioxidine 银簇与抗菌药物二氧六环的复合物建模

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010115

A. V. Soloviev, A. Yu. Ermilov, Yu. N. Morosov, T. I. Shabatina

{"title":"Modelling Silver Cluster Complexes with the Antibacterial Medication Dioxidine","authors":"A. V. Soloviev, A. Yu. Ermilov, Yu. N. Morosov, T. I. Shabatina","doi":"10.3103/S0027131424010115","DOIUrl":"10.3103/S0027131424010115","url":null,"abstract":"The structures of small silver clusters (Agn, n = 1–3, 13) and their complexes with molecules of the antibacterial drug 2,3-bis-(hydroxymethyl)quinoxaline-N,N′-dioxide–dioxidine (Dx) are calculated using the electron density functional method in the DFT/B3LYP5 version. The features of the geometric structure and energy of the metal cluster–dioxidine ligand interaction are considered depending on the size (nuclearity) of the metal cluster. For small clusters (n = 1–3), a tendency for the metal to be coordinated to only one of the oxygen atoms of the ligand molecule is revealed. The most stable complexes are the silver trimers Dx–Ag3 and the icosahedral silver cluster Dx–Ag13, which are coordinated simultaneously with two oxygen atoms of the hydroxyl groups of the dioxidine molecule. The difference between the obtained optimized structures of the silver–dioxidine complexes and the previously studied silver complexes with hydroxide ligands, for which the hydrogen atom of the ligand hydroxyl group is displaced during the interaction, is shown.","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"79 1","pages":"21 - 26"},"PeriodicalIF":0.7,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140602647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spectrophotometric Determination of Copper(II) in Soil in the Form of a Pyrogallol Red Complex in the Presence of Surfactants 分光光度法测定存在表面活性剂的土壤中以焦耳酚红络合物形式存在的铜(II)

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010085

S. E. Pratskova, D. R. Khudaiberdina

引用次数: 0

The Influence of Polyvinyl Alcohol on the Stability of Aqueous Dispersions of Nanodiamonds 聚乙烯醇对纳米金刚石水分散体稳定性的影响

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010103

O. A. Soboleva

引用次数: 0

Lattice Tilings of a Plane into Polyominoes and Molecular Layers in Crystal Structures: Structural Class cm, Z = 2(m) 晶体结构中多面体和分子层的平面层叠：结构类 cm，Z = 2(m)

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010097

K. G. Seravkin, K. A. Potekhin, A. M. Banaru

引用次数: 0

Rheology of Structured Liquids: Dependence of Dynamic Moduli on Strain Amplitude 结构液体流变学：动态模量与应变振幅的关系

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010061

V. N. Matveenko, E. A. Kirsanov

引用次数: 0

Evaluation of the Nutritional Value, Toxins and Pollutants in Mazandaran Rice and Detection of the Rice Health Level 评估马赞达兰大米的营养价值、毒素和污染物，检测大米的健康水平

IF 0.7

Moscow University Chemistry Bulletin Pub Date : 2024-04-02 DOI: 10.3103/S0027131424010024

Ahmad Gholizadeh, Seyed Esmaeil Yazdanpanah

{"title":"Evaluation of the Nutritional Value, Toxins and Pollutants in Mazandaran Rice and Detection of the Rice Health Level","authors":"Ahmad Gholizadeh,  Seyed Esmaeil Yazdanpanah","doi":"10.3103/S0027131424010024","DOIUrl":"10.3103/S0027131424010024","url":null,"abstract":"As insecticides, fungicides, heavy metals, and aflatoxins enter the food chain, they cause adverse effects on living organisms and humans. Given that rice is a widely-consumed food in Iran, the present study aimed to investigate the probability of the existence of insecticides, fungicides, heavy metals, and aflatoxins, as well as the nutritional value of rice in Mazandaran province. To this end, four cultivars of rice, namely Tarom, Fajr, Neda, and Shiroodi rice were collected from farms in the region, and after preparation, the concentration of pollutants in rice was measured in different ways in the laboratory. SPSS 25 software was used to analyze data. Based on the findings, the average nutritional value of four cultivars of rice was high in terms of protein (8.575 ± 0.298 g), fiber (less than 1), fat (1.2 g), carbohydrates (81.725 ± 0.512 g), calcium (405.64 ± 0.81 ppm), and B vitamins, where the average of vitamin B1 was 2.775 ± 1.305 g, vitamin B2 was 3.5 ± 1.62 g, vitamin B3 and B6 were less than 0.2, and vitamin B12 was less than 5. Heavy metals (less than 0.1 ppm), arsenic (0.095 ± 0.338 ppm), and cadmium (less than 0.025 ppm) were lower than the standard level. Due to the proximity of heavy metals to the standard, its status was considered critical. The average concentrations of aflatoxins, insecticides, fungicides, and herbicides were standard in different cultivars of rice. Given the nutritional value, the standard level of pollutants, and the health of Iranian rice species, rice consumption is recommended in diets and exports.","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"79 1","pages":"54 - 62"},"PeriodicalIF":0.7,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0