{"title":"ANAL CANCER IN A RENAL TRANSPLANT RECIPIENT: A CASE REPORT AND LITERATURE REVIEW.","authors":"Mislav Mokos, Marijana Ćorić, Hrvoje Silovski, Nikolina Bašić-Jukić","doi":"10.20471/acc.2023.62.03.19","DOIUrl":"10.20471/acc.2023.62.03.19","url":null,"abstract":"<p><p>Anal carcinoma is a rare tumor in the general population accounting for 1%-2% of all malignancies. Most anal cancers are squamous cell carcinomas. Human papillomavirus and immunosuppression are the main risk factors for developing anal squamous cell carcinoma. Therefore, the incidence rate of anal squamous cell carcinoma is significantly higher in renal transplant recipients than in the general population. We present a patient who developed anal cancer nine years after renal transplantation. Since there was a significant diagnostic delay in our patient, we would like to emphasize the importance of regular screening for anal cancer in renal transplant recipients.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 3","pages":"556-560"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11414003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nina Sulen, Tatjana Šimurina, Milan Milošević, Miroslav Župčić, Boris Mraović
{"title":"VALIDATION OF THE QUALITY OF RECOVERY-40 QUESTIONNAIRE ADAPTED FOR CROATIAN POPULATION.","authors":"Nina Sulen, Tatjana Šimurina, Milan Milošević, Miroslav Župčić, Boris Mraović","doi":"10.20471/acc.2023.62.03.4","DOIUrl":"10.20471/acc.2023.62.03.4","url":null,"abstract":"<p><p>Quality of recovery after anesthesia is an important indicator of patient postoperative outcomes. Quality of Recovery-40 (QoR-40) is a validated and widely used multidimensional 40-item questionnaire that measures postoperative quality of recovery. The aim of this study was to perform translation and psychometric validation of the Croatian version of QoR-40, which included validity, reliability, responsiveness, and clinical acceptability. The QoR-40 and Short Form-36 (SF-36) questionnaires were administered to patients undergoing general anesthesia for elective surgery on the day before surgery and on postoperative day 3. The quality of recovery was also assessed with visual analog scale (VAS) 0-100. Of 192 enrolled patients, 162 completed the study protocol. Convergent validity assessed by Pearson correlation (r) between the QoR-40 and VAS scores was 0.68 (p<0.001). There were moderate correlations of QoR-40 with SF-36 Physical component scale (r=0.521; p<0.001) and with SF-36 Mental component scale (r=0.580; p<0.001). Construct validity was supported by negative correlation with the length of hospital stay (r=-0.21; p=0.007) and significant difference in total postoperative QoR-40 scores between patients with and without postoperative complications (p<0.001). Internal consistency of the global QoR-40 was high (Cronbach's α=0.93) and of the QoR-40 dimensions it was moderate to high (≥0.714). Split-half coefficient was 0.87, Cohen's effect size was 0.81, and standardized response mean was 0.762. Our translated QoR-40 is a valid, reliable and comprehensive questionnaire for measuring quality of postoperative recovery across surgery spectrum in Croatian population with psychometric properties similar to the original version.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 3","pages":"426-436"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11414013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Kalagac Fabris, S Zanghirella Maretić, M Petrinović, T Tepšić
{"title":"MINIMALLY INVASIVE DIAGNOSTIC BLOCK AND PERCUTANEOUS RADIOFREQUENCY ABLATION IN THE TREATMENT OF CHRONIC HIP PAIN - REVIEW ARTICLE.","authors":"L Kalagac Fabris, S Zanghirella Maretić, M Petrinović, T Tepšić","doi":"10.20471/acc.2023.62.s4.10","DOIUrl":"10.20471/acc.2023.62.s4.10","url":null,"abstract":"<p><p>The hyperactive \"baby boom\" generation is gradually aging, and chronic hip pain has become an increasingly common problem. Most patients with hip pain experience symptoms ranging from mild discomfort to severe pain. They can control the pain with conservative measures, but it inevitably progresses, causing a gradual decline in the quality of life. Conservative therapeutic approaches to hip pain include paracetamol, nonsteroidal anti-inflammatory drugs, narcotics and a variety of physical therapies. Total hip arthroplasty surgery is the only option for patients who experience a gradual decrease in mobility over time and whose pain is unaffected by a conservative approach. For most patients, surgical treatment is a good way to restore quality of life and reduce pain levels, However, this aggressive surgery is not possible in some patients. Many comorbidities in old age limit access to total arthroplasty, while the younger population is at an age where they want to delay surgical treatment. In both of these groups, it is desirable to consider other treatment options and techniques. Minimally invasive percutaneous partial sensory denervation of the hip joint has today become an option that can achieve significant success in providing the desired pain relief without the employment of a surgical knife. Today, there are different modalities for performing this procedure, ranging from diagnostic-pharmacological, radiofrequency (thermal, pulsating and cooled) and cryoablative modes. There is currently broad evidence that suggests that the use of fluoroscopically guided percutaneous radiofrequency ablation of the periarticular branches of the hip joint can provide pain relief for as long as 12-18 months.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 Suppl4","pages":"68-76"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anja Petričević, Dino Budrovac, Ivana Lenz, Slavica Kvolik
{"title":"SUGGESTIVE PREPARATION OF PATIENTS USING INTRAVENOUS KETOPROFEN AS A PART OF POSTOPERATIVE PAIN MANAGEMENT IN ELECTIVE ABDOMINAL SURGERY.","authors":"Anja Petričević, Dino Budrovac, Ivana Lenz, Slavica Kvolik","doi":"10.20471/acc.2023.62.s4.1","DOIUrl":"10.20471/acc.2023.62.s4.1","url":null,"abstract":"<p><p>Suggestive preparation before surgery may have a placebo effect and can reduce perioperative consumption of analgesics. A total of 77 adult patients undergoing elective cholecystectomy and hernioplasty were included in this prospective study. All patients were given 100 mg of ketoprofen intravenously and were assigned to two groups. The first group was not informed about analgesia (no preparation, NP group), and the second group were told that they will receive a strong painkiller (suggestive preparation, SP group). Pulse rate, blood pressure and VAS scores were registered in all patients immediately before anesthesia induction in the operating room (T1), after waking up in the recovery room (T2), 6 hours after surgery at the surgical ward (T3) and on the morning after surgery in the surgical ward (T4), at rest and during movement. Rescue nonsteroidals were offered to patients with VAS 3-4, and opioids for VAS ≥5. The patients in the SP group had lower VAS scores in all measurements and lower opioid consumption. A statistically significant difference was observed in VAS2 measurement during movement (3 [2-5] vs. 2 [0-3.75] in the NP and SP group, P=0.008). SP had a placebo effect and reduced VAS scores as well as opioid consumption.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 Suppl4","pages":"5-11"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ASSOCIATION BETWEEN ALLERGIC REACTIONS AND LIP INFLAMMATORY LESIONS (CHEILITIS).","authors":"Tadeja Blagec, Iva Crnarić, Damir Homolak, Nives Pondeljak, Marija Buljan, Liborija Lugović-Mihić","doi":"10.20471/acc.2023.62.03.3","DOIUrl":"10.20471/acc.2023.62.03.3","url":null,"abstract":"<p><p>The purpose of this study was to examine the possible association between cheilitis and allergic reactions, and to use allergy skin tests to identify the allergens that induce allergic reactions in cheilitis patients (type I and type IV). We included 50 patients with recurrent cheilitis (reversible cheilitis) who were dermatologically examined and agreed to undergo allergy skin tests, i.e., patch test and prick test. Additionally, clinical pictures and patient mental stress levels were examined using the Perceived Stress Scale (PSS). Positive prick tests (atopy) were recorded in 84% of patients with cheilitis. The most frequently found allergens were contact allergens (54%) (cobalt chloride, nickel sulfate and thimerosal) and inhalant allergens (46%). The patch test positive subjects who used cosmetic, hygiene, and decorative products were significantly more likely to have swollen and red lips than the patch test negative subjects. Also, low stress levels were recorded less frequently in patients with confirmed allergies than in non-allergic patients. The results indicated a higher incidence of cheilitis in the people prone to allergies (atopics) and confirmed an association between cheilitis and allergies. To our knowledge, this is the first study in patients with cheilitis, which simultaneously analyzed allergies, their clinical features and PSS in the same patients.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 3","pages":"415-425"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iva Dimitrijević, Dijana Hnatešen, Ivan Radoš, Dino Budrovac, Ozana Katarina Tot, Roman Pavić, Vanja Matković, Ivana Gusar, Maja Čebohin, Ivan Omrčen
{"title":"BELIEFS ABOUT MEDICINES QUESTIONNAIRE (BMQ) IN PATIENTS WITH CHRONIC PAIN.","authors":"Iva Dimitrijević, Dijana Hnatešen, Ivan Radoš, Dino Budrovac, Ozana Katarina Tot, Roman Pavić, Vanja Matković, Ivana Gusar, Maja Čebohin, Ivan Omrčen","doi":"10.20471/acc.2023.62.s4.3","DOIUrl":"10.20471/acc.2023.62.s4.3","url":null,"abstract":"<p><p>The aim of this study was to identify demographic and disease characteristics associated with different medication beliefs of patients with chronic non-malignant pain and to investigate beliefs about medicines and their association with medicine adherence. Data were collected from 202 patients using the Beliefs about Medicines Questionnaire (BMQ) and the Numeric Rating Scale (NRS). According to four different attitudinal constructs, the results indicate that the majority of patients were Indifferent, followed by Distrustful and Mixed-feelings, whereas the lowest proportion of patients were In-favour. The highest patient age was found in the In-favour and Indifferent constructs. Primary education level was the most represented in the In-favour construct. The most patients in the In-favour, Indifferent and Distrustful constructs used a combination of non-steroidal anti-inflammatory drugs (NSAID) and opioids. In the Mixed-feelings construct, patients mostly used a combination of paracetamol and NSAIDs. Most patients in the In-favour and Mixed-feelings construct reported severe pain. In the Indifferent and Distrustful constructs, most patients reported moderate pain. The study results indicate am association between some demographic characteristics and medications beliefs and that constructs could be predictors of adherence. The BMQ can be used to identify patients who are at risk of non-adherence and can be used in multidisciplinary pain programs.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 Suppl4","pages":"19-26"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BURNOUT SYNDROME IN ANESTHESIOLOGISTS WORKING WITH MECHANICALLY VENTILATED COVID PATIENTS AT THE UNIVERSITY HOSPITAL CENTER OSIJEK.","authors":"Lucija Brdar, Ivan Radoš, Dijana Hnatešen","doi":"10.20471/acc.2023.62.s4.4","DOIUrl":"10.20471/acc.2023.62.s4.4","url":null,"abstract":"<p><p>This study aimed to examine the incidence and intensity of burnout syndrome among the anesthesiologists who worked with COVID patients in the COVID intensive care unit (Respiratory Centre) and among anesthesiologists and clinicians who did not work in a respiratory ICU during the pandemic in order to compare the difference in the incidence of burnout syndrome and to examine whether there is a difference in burnout syndrome regarding gender, age and level of medical education. Therefore, a cross-sectional study was conducted. The study included 60 participants; 30 of whom were physicians who worked in the respiratory ICU and 30 who did not work in the respiratory ICU during the COVID-19 pandemic. The results were obtained using a questionnaire to classify participants as being without burnout symptoms, in the initial phase of burnout, or having a high degree of burnout. Based on the results, we found that 53% of all physicians presented with burnout syndrome, and the majority of them were anesthesiologists (30%). Furthermore, 37% of anesthesiologists were in the group with an initial phase of burnout and 20% in the group with a high burnout. Among female anesthesiologists, the syndrome was observed in 58% of all cases. In the group of anesthesiologists older than 35 years, 59% of the cases of burnout syndrome were present, where as burnout syndrome was present in 54% of younger anesthesiologists (younger than 35 years old). There was a higher proportion of burnout syndrome among the participants than in previous studies. The anesthesiologists who worked with seriously ill COVID patients during the pandemic were predominant among the physicians with a higher proportion of burnout syndrome. Symptoms were more common among women, physicians older than 35 and specialists.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 Suppl4","pages":"27-33"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ANALYSIS OF TIME, PLACE AND METHOD OF SUICIDE IN THE AREA OF BJELOVAR-BILOGORA COUNTY IN THE 1988-2017 PERIOD.","authors":"Ivana Jelašić, Vinko Čatipović","doi":"10.20471/acc.2023.62.03.1","DOIUrl":"10.20471/acc.2023.62.03.1","url":null,"abstract":"<p><p>The aim of the study was to analyze changes in the number of suicides associated with seasonal variables, calendar month, time of day <i>versus</i> variable location and method of suicide. Data were obtained from the Analytical Police Department of Bjelovar-Bilogora County for the 1988-2017 period. The process of Croatian application process into the European Union, accompanied by economic and social changes, was a significant socioeconomic event, which divided the analyzed period into two parts. Significant changes in the impact of the analyzed variables on the suicides committed in the two observed periods were tested with the χ<sup>2</sup>-test and Fisher exact test. Consistency of the results, as well as absence of the impact of significant changes would show less susceptibility of the covariate variable to the effect of socioeconomic factors. In the case of time of day and location of the suicides, there was no significant difference when comparing results between the 1988-2004 and 2005-2017 periods; however, a statistically significant difference was confirmed when considering the month of suicide (February) and season (winter, borderline result for autumn). Statistically, the most significant changes were found in the methods of suicide. The two observed periods differed in the mean suicide rate.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 3","pages":"397-405"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11414007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selim Çınaroğlu, Kayhan Karakuş, Hacı Keleş, Mustafa Kaçmaz
{"title":"EVALUATION OF PATIENTS WITH COVID-19 IN THE EARLY HYPOXEMIC STAGE AND PATIENTS WITH VIRAL RESPIRATORY TRACT INFECTION IN TERMS OF PULMONARY HYPERTENSION.","authors":"Selim Çınaroğlu, Kayhan Karakuş, Hacı Keleş, Mustafa Kaçmaz","doi":"10.20471/acc.2023.62.03.10","DOIUrl":"10.20471/acc.2023.62.03.10","url":null,"abstract":"<p><p>Arterial hypoxemia occurs in many COVID-19 patients. Hypoxemia is one of the causes of pulmonary hypertension (PH). Main pulmonary artery dilatation and the main pulmonary artery diameter (mPAD) to ascending aorta diameter (AAD) ratio of ≥1 are significant findings regarding PH. In this study, COVID-19 patients and non-COVID-19 patients with viral respiratory tract infection were evaluated retrospectively in terms of PH. A total of 124 patients (71 male and 53 female), age range 18-85 years, were included in the study as case group and control group. Thoracic computed tomography (CT) images, blood and biochemical parameters, and demographic information were compared between the case group and control group. The normality of numerical variables was examined with Kolmogorov-Smirnov test and homogeneity of the variances with Levene's test. This is the first study researching the effect of early hypoxemic stage COVID-19 infection on development of PH. As a result, it was specified that COVID-19 infection had no effects on mPAD, whereas it had a positive effect on AAD and thus led to a decrease in the mPAD/AAD ratio. Through these values, which could be easily calculated from thoracic CT images, the changes caused by COVID-19 infection on vessel diameters were put forward.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 3","pages":"478-485"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11414004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Željka Dragila, Andrea Dorokazi, Damir Mihić, Domagoj Loinjak, Miroslav Šram, Tatjana Bačun
{"title":"GLUCOSE AND SODIUM LEVELS AS DISEASE OUTCOME PREDICTORS IN CRITICALLY ILL PATIENTS.","authors":"Željka Dragila, Andrea Dorokazi, Damir Mihić, Domagoj Loinjak, Miroslav Šram, Tatjana Bačun","doi":"10.20471/acc.2023.62.03.13","DOIUrl":"10.20471/acc.2023.62.03.13","url":null,"abstract":"<p><p>The main aim of this study was to examine the association of glucose and sodium level with diagnosis and disease outcome of critically ill patients. Glucose and sodium concentrations of 283 patients admitted in critical condition to the Intensive Care Unit of the Department of Internal Medicine in a period from November 1, 2015 to February 28, 2017 were reviewed. The most common diagnoses in critically ill patients were acute kidney injury (26.1%) and sepsis (including septic shock, 22.3%). Significantly lower glucose concentration was observed in patients with acute kidney injury (p=0.02), whereas patients in sepsis and septic shock had a significantly higher sodium concentration (p=0.04). Higher glucose level was related to higher mortality rate (p=0.001). On the other hand, sodium level was not significantly associated with survival. Higher mortality, as well as higher glucose concentration were more common in patients older than 65 years (p<0.001). Study results showed significantly lower glucose concentrations in patients with acute kidney injury, whereas in patients older than 65, glucose concentration was significantly higher. Patients in sepsis and septic shock had significantly higher sodium concentrations. Higher concentration of glucose was connected with higher mortality in the elderly, whereas sodium concentration did not show connection with mortality.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"62 3","pages":"510-518"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11414012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}