Microgravity Science and Technology最新文献

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Correction: Role of Boundary Conditions and Volumetric Heating in Electrothermal Anisotropic Porous Convection 修正:边界条件和体积加热在电热各向异性多孔对流中的作用
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-05-09 DOI: 10.1007/s12217-026-10255-2
C. S. Rachitha, C. E. Nanjundappa, I. S. Shivakumara
{"title":"Correction: Role of Boundary Conditions and Volumetric Heating in Electrothermal Anisotropic Porous Convection","authors":"C. S. Rachitha, C. E. Nanjundappa, I. S. Shivakumara","doi":"10.1007/s12217-026-10255-2","DOIUrl":"10.1007/s12217-026-10255-2","url":null,"abstract":"","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147830078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermal Analysis of Vapour Bubble under the Impact of Peristaltic Motion Inside a Vertical Cylindrical Tube 垂直圆柱管内气泡在蠕动运动影响下的热分析
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-05-06 DOI: 10.1007/s12217-026-10254-3
Saliha Zafar, Ambreen Afsar Khan
{"title":"Thermal Analysis of Vapour Bubble under the Impact of Peristaltic Motion Inside a Vertical Cylindrical Tube","authors":"Saliha Zafar,&nbsp;Ambreen Afsar Khan","doi":"10.1007/s12217-026-10254-3","DOIUrl":"10.1007/s12217-026-10254-3","url":null,"abstract":"<div><p>This article presents the growth analysis of a vapour bubble present inside a cylindrical tube; peristaltic movement is assumed at the walls of the tube. The study is carried out under the impact of a magnetic field and slip conditions at the wall. The mathematical model of the problem, based on momentum and energy equations, is solved, and analytical solutions are obtained for velocity and temperature fields. The growth of the bubble is analyzed by plotting graphs of radius and radius velocity of the bubble. It is revealed that vapour bubble starts shrinking as the applied magnetic field intensifies. The variation in velocity and temperature profiles for various emerging parameters is also observed through graphs. Understanding the behavior of vapour bubbles is crucial for enhancing the efficiency of power plants, as the formation of these bubbles inside the fuel rods directly impacts thermal performance; therefore, this study aims to provide insight into the dynamics of vapour bubbles flowing within a peristaltic flow.</p></div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147829640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stability of the Cattaneo–Christov–Jordan–Mariano Model for Thermal Convection in a Porous Medium with Variable Gravity 变重力多孔介质热对流Cattaneo-Christov-Jordan-Mariano模型的稳定性
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-04-22 DOI: 10.1007/s12217-026-10252-5
Amit Mahajan, Sonali Dagar
{"title":"Stability of the Cattaneo–Christov–Jordan–Mariano Model for Thermal Convection in a Porous Medium with Variable Gravity","authors":"Amit Mahajan,&nbsp;Sonali Dagar","doi":"10.1007/s12217-026-10252-5","DOIUrl":"10.1007/s12217-026-10252-5","url":null,"abstract":"<div>\u0000 \u0000 <p>This study examines thermally induced convective flow in a fluid-saturated porous medium, where momentum transport follows extended Darcy’s law and thermal transport is governed by the Cattaneo–Christov–Jordan–Mariano (CCJM) model, allowing for variations in the gravitational field. The CCJM framework generalizes the classical Fourier heat conduction model to include thermal diffusion, finite thermal relaxation, and inertial effects, while the momentum equation accounts for the presence of a spatially varying gravitational field. Collectively, these effects provide a more physically consistent depiction of heat transport and convective behavior in porous media. The onset of convection is examined through a combined linear analysis, encompassing stationary and oscillatory modes, together with a nonlinear stability framework. Linear stability is evaluated using the normal-mode technique, while the nonlinear stability equations are obtained through the energy method. Numerical simulations are performed using MATLAB to determine the critical stability parameters, and the corresponding plots depict the resulting stability characteristics. The Galerkin single-term approach is used to measure the critical Rayleigh number and the corresponding wavenumber. Four distinct gravity-variation profiles are examined, revealing that the gravity-modulation parameter <span>(gamma )</span> may exert either a stabilizing or destabilizing influence depending on the specific profile considered. The numerical illustrations further highlight the roles of the parameters <span>(zeta )</span>, <span>(Sg)</span>, and <span>(Va)</span> in shaping the overall stability behavior of the system. Collectively, these results highlight the joint influence of gravity modulation and material parameters on the initiation of convection, offering enhanced insight into the thermal stability of viscoelastic porous media within the Cattaneo–Christov–Jordan–Mariano (CCJM) framework.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147738522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simulation of Multiphase Flows in Porous Media Under Microgravity Conditions 微重力条件下多孔介质中多相流动的模拟
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-04-17 DOI: 10.1007/s12217-026-10250-7
Nickolay Smirnov, Evgeniya Skryleva, Lusine Paremskaya, Mikhail Paremski, Anastasia Manakhova, Elena Mikhalchenko, Fang Wang
{"title":"Simulation of Multiphase Flows in Porous Media Under Microgravity Conditions","authors":"Nickolay Smirnov,&nbsp;Evgeniya Skryleva,&nbsp;Lusine Paremskaya,&nbsp;Mikhail Paremski,&nbsp;Anastasia Manakhova,&nbsp;Elena Mikhalchenko,&nbsp;Fang Wang","doi":"10.1007/s12217-026-10250-7","DOIUrl":"10.1007/s12217-026-10250-7","url":null,"abstract":"<div>\u0000 \u0000 <p>The article considers an experimental and numerical study of multiphase flows in a Hele-Shaw cell. The horizontal Hele-Shaw cell makes it possible to simulate flows in porous media in microgravity. The results of numerical simulation of a three-phase flow are presented. The cases when the boundaries between the phases are stable and the cases when the Saffman-Taylor instability develops at the boundary are considered. The results of the numerical simulation are compared with the conducted experiments. The paper also examines the pressure distribution in the Hele-Shaw cell during a three-phase flow.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hfq Positively Regulated the Proliferation Ability of Escherichia coli K-12 Under Simulated Microgravity Condition Hfq正调控模拟微重力条件下大肠杆菌K-12的增殖能力
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-04-06 DOI: 10.1007/s12217-026-10249-0
Xinxin Li, Ya Li, Huaxian Li, Quanxian Guo, Wentian Zhang, Manzhi Gao, Sumin Li, Hanxiao Zhang, Weiwei Yan, Yong Liu, Peijun Han, Wenlan Wang
{"title":"Hfq Positively Regulated the Proliferation Ability of Escherichia coli K-12 Under Simulated Microgravity Condition","authors":"Xinxin Li,&nbsp;Ya Li,&nbsp;Huaxian Li,&nbsp;Quanxian Guo,&nbsp;Wentian Zhang,&nbsp;Manzhi Gao,&nbsp;Sumin Li,&nbsp;Hanxiao Zhang,&nbsp;Weiwei Yan,&nbsp;Yong Liu,&nbsp;Peijun Han,&nbsp;Wenlan Wang","doi":"10.1007/s12217-026-10249-0","DOIUrl":"10.1007/s12217-026-10249-0","url":null,"abstract":"<div>\u0000 \u0000 <p>Simulated microgravity enhances <i>Escherichia coli</i> (<i>E. coli</i>) proliferation ability, but the underlying mechanisms remain unclear. In this study, we cultured <i>E. coli</i> in a three-dimensional rotational environment for 14 days to establish simulated microgravity strains (SMG). Compared to normal gravity strains (NG), SMG exhibited enhanced growth rate, and motility. Hfq plays a crucial role in proliferation ability in terms of growth rate and motility in <i>E. coli</i>. And it is worth noting that, compared with the NG, the expression of <i>hfq</i> in <i>E. coli</i> was upregulated in SMG. The expression of genes including <i>minD</i>, <i>minE</i>, <i>flhC</i> and <i>flhD</i> upregulated in SMG. To investigate the effect of <i>hfq</i> on <i>E. coli</i> proliferation ability, we knocked out <i>hfq</i> in <i>E. coli</i> to establish a Δ<i>hfq E. coli</i> strain and cultured it under simulated microgravity conditions for 14 days (Δ<i>hfq</i> SMG). The Δ<i>hfq</i> SMG exhibited reduced growth rate and motility compared to SMG. Meanwhile, the expression levels of <i>minD</i>, <i>minE</i>, <i>flhC</i> and <i>flhD</i> were downregulated. Replenishing <i>hfq</i> to Δ<i>hfq</i> SMG could restore growth rate and motility, and re-activate the downregulated genes. In conclusion, it is demonstrated that <i>hfq</i> played a significant role in the proliferation ability of <i>E. coli</i> under simulated microgravity condition and this effect might be closely related to the proliferation ability -related genes of <i>E. coli</i>. This study may provide a new idea for preventing and controlling opportunistic pathogenic bacterial infections during aerospace missions.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147642736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: A Comprehensive Review of Flashing Phenomena and Evaporation Wave Propagation in Superheated Liquids 修正:过热液体中闪蒸现象和蒸发波传播的综合综述
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-04-01 DOI: 10.1007/s12217-026-10251-6
Kush Kumar Dewangan, Ojas Satbhai, Satish Kumar Gavel, Kiran Kumar Rokhade
{"title":"Correction: A Comprehensive Review of Flashing Phenomena and Evaporation Wave Propagation in Superheated Liquids","authors":"Kush Kumar Dewangan,&nbsp;Ojas Satbhai,&nbsp;Satish Kumar Gavel,&nbsp;Kiran Kumar Rokhade","doi":"10.1007/s12217-026-10251-6","DOIUrl":"10.1007/s12217-026-10251-6","url":null,"abstract":"","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147606673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Numerical Research on the Sloshing Suppression Performance of Baffles in Partially Filled Liquid Storage Tanks 部分充液储罐挡板抑制晃动性能的数值研究
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-27 DOI: 10.1007/s12217-026-10248-1
Lie Wei, Xiao Zhao, Hai Lin, Kai Li, Yu Liu
{"title":"Numerical Research on the Sloshing Suppression Performance of Baffles in Partially Filled Liquid Storage Tanks","authors":"Lie Wei,&nbsp;Xiao Zhao,&nbsp;Hai Lin,&nbsp;Kai Li,&nbsp;Yu Liu","doi":"10.1007/s12217-026-10248-1","DOIUrl":"10.1007/s12217-026-10248-1","url":null,"abstract":"<div>\u0000 \u0000 <p>Numerical simulations were conducted to examine the effects of various anti-sloshing structures on the hydrodynamic behavior of liquid sloshing in tanks. The analysis systematically evaluated free-surface evolution, centroid motion, and force responses over a range of filling ratios. The results indicate that the filling ratio is a dominant factor governing sloshing intensity, with increased liquid mass leading to higher peak forces and slower decay rates. Moreover, internal structures substantially alter liquid migration patterns, thereby modifying the dominant frequency, peak force magnitude, and damping characteristics. Among the configurations considered, the sidewall partition (Configuration 2) exhibited superior mitigation performance at low and high filling ratios, yielding the lowest force and frequency in conjunction with the highest damping ratio. Conversely, the double-side perforated structure (Configuration 4) promoted enhanced momentum exchange, resulting in the highest force and frequency, albeit accompanied by rapid initial attenuation. The single-side perforated configuration (Configuration 3) displayed pronounced nonlinear behavior, characterized by rapid early decay followed by a marked reduction in attenuation rate. Collectively, these findings offer valuable guidance for the design and optimization of effective slosh-mitigation systems.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanism and Propagation Mode of Upward Flame Spread on Solid Material Surface Under Gravity Effects 重力作用下固体材料表面火焰向上传播的机理与传播模式
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-25 DOI: 10.1007/s12217-026-10247-2
Yuhan Jiang, Feng Zhu, Shuangfeng Wang
{"title":"Mechanism and Propagation Mode of Upward Flame Spread on Solid Material Surface Under Gravity Effects","authors":"Yuhan Jiang,&nbsp;Feng Zhu,&nbsp;Shuangfeng Wang","doi":"10.1007/s12217-026-10247-2","DOIUrl":"10.1007/s12217-026-10247-2","url":null,"abstract":"<div>\u0000 \u0000 <p>The mechanism and steady propagation of upward flame is key aspects of the solid materials flammability. The controlling mechanisms of upward flame spread over solid fuels were studied through a numerical modeling. The objective of the present study is to gain insight into the intrinsic mechanisms of the steady spread process of a solid fuel, as well as to gain a more comprehensive understanding of the critical conditions for the steady spread process. For this purpose, a two-dimensional numerical model has been developed using the Fire Dynamic Simulator (FDS6) code, in which both solid-phase and gas-phase reactions are calculated. Flame spread process with a series of gravity levels were studied, and the buoyant flow effects were discussed. The simulation results show that with the decrease of the buoyant flow, three distinct flame spread modes are identified, namely the skipping mode and splitting mode due to advanced pyrolysis of downstream fuel, and steady spread mode for subcritical gravity. When the buoyancy is weak enough, the flame can spread upward with a steady rate, which is dominated by the constant air supply caused by the backflow zone aside the flame. Under these conditions, the flame spread rate increases linearly with the increased gravity. Reduced-pressure experiments were carried out to examine the flame spread modes under suppressed buoyancy conditions, which shows good agreements with numerical results.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Simulated Microgravity on Krüppel-Like Factor Expression in Gastrointestinal Cells of Aged Rats 模拟微重力对老龄大鼠胃肠道细胞kr<s:1> ppel样因子表达的影响
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-23 DOI: 10.1007/s12217-026-10246-3
Ahmed Al-Dwairi, Tayseer Afifi, Othman Al-Shboul, Abdulsalam Bani Hamad, Doa’a Al-u’datt
{"title":"Effect of Simulated Microgravity on Krüppel-Like Factor Expression in Gastrointestinal Cells of Aged Rats","authors":"Ahmed Al-Dwairi,&nbsp;Tayseer Afifi,&nbsp;Othman Al-Shboul,&nbsp;Abdulsalam Bani Hamad,&nbsp;Doa’a Al-u’datt","doi":"10.1007/s12217-026-10246-3","DOIUrl":"10.1007/s12217-026-10246-3","url":null,"abstract":"<div>\u0000 \u0000 <p>Microgravity alters gastrointestinal physiology, posing health risks during spaceflight. Krüppel-like factors (KLFs) are key transcriptional regulators of intestinal integrity, yet their behavior under microgravity in aged tissues remains unclear. Understanding these changes is vital for protecting gut health in aging individuals exposed to such environments. This study aimed to determine the effect of simulated microgravity on mRNA expression of KLFs in small intestine and colon cells and smooth muscles. This study employed a hindlimb unloading model to simulate microgravity conditions in laboratory-aged rats. A total of 15 male Sprague Dawley rats, aged 18–24 months, were divided into control (<i>n</i> = 7) and suspended (<i>n</i> = 8) groups, with suspension being induced for a period of two weeks. Following the intervention, small intestine and colon tissues were harvested for molecular analysis. Gene expression levels of KLFs (4, 5, 6 and 9) were quantitatively assessed using real-time reverse transcription polymerase chain reaction (RT-qPCR). Immunohistochemistry was employed to detect and quantify KLFs expression patterns. Significant morphological and molecular alterations were observed in intestinal tissues under simulated microgravity. Hindlimb suspension resulted in a pronounced reduction in small intestinal villus length (<i>P</i> &lt; 0.0001) and a marked decrease in Paneth cell count (<i>P</i> &lt; 0.0001). Gene expression analysis revealed tissue-specific modulation of Krüppel-like factors (KLFs). In the small intestine, KLF6 expression significantly declined (<i>P</i> = 0.047), while KLF9 levels increased (<i>P</i> = 0.035). In small intestinal smooth muscle, KLF5 was significantly downregulated (<i>P</i> = 0.009). Conversely, colonic smooth muscle exhibited significant upregulation of KLF4 (<i>P</i> = 0.032) and KLF5 (<i>P</i> &lt; 0.001), alongside a significant reduction in KLF9 (<i>P</i> = 0.021). This study highlighted the impact of simulated microgravity, via hindlimb suspension, on intestinal structure and KLF gene expression in aged rats. Villus length was significantly reduced, indicating impaired absorptive function, while Paneth cell depletion suggests weakened mucosal immunity. Although changes in crypt depth and muscle thickness were minimal, molecular analysis showed downregulation of KLF6 and upregulation of KLF9, pointing to disrupted epithelial homeostasis. KLF4 and KLF5 levels remained stable at the mRNA level.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential Gene Expression of Acidovorax sp.1,608,163 under Simulated Microgravity Acidovorax sp.1,608,163在模拟微重力下的差异基因表达
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-21 DOI: 10.1007/s12217-026-10245-4
Eduardo Jacobo Gutierrez, Madhusudan Choudhary, Alexis Ho, Anand B. Karki
{"title":"Differential Gene Expression of Acidovorax sp.1,608,163 under Simulated Microgravity","authors":"Eduardo Jacobo Gutierrez,&nbsp;Madhusudan Choudhary,&nbsp;Alexis Ho,&nbsp;Anand B. Karki","doi":"10.1007/s12217-026-10245-4","DOIUrl":"10.1007/s12217-026-10245-4","url":null,"abstract":"<div>\u0000 \u0000 <p>Previous studies reported that microorganisms, including several bacterial species, under microgravity stress undergo differential gene expression leading to diverse physiological responses such as increased growth, virulence, antibiotic resistance, and biofilm production. This study examines the gene-expression differences of <i>Acidovorax sp</i>. 1,608,163 under normal and simulated microgravity conditions. Strains of the <i>Acidovorax species</i> are free-living, environmental commensals, plant or human opportunistic pathogens that can infect a variety of crops, including corn, rice, oats, and wheat. The hypothesis that “<i>Acidovorax</i> grown under microgravity alters the gene expression patterns” is tested by comparing transcriptomic data of bacterial cultures at the log (42 h) and stationary (72 h) phases grown under normal and microgravity conditions. Total RNA was extracted and reverse transcribed, and then the cDNA was sequenced using the Illumina HiSeq 4000 platform. Results revealed the difference in growth rates, which were significantly higher under microgravity conditions than under normal gravity conditions. Of the total of 678 differentially expressed genes, 232 (34.22%) and 446 (65.78%) genes were up- and down-regulated in the log phase, respectively, whereas the total of 231 differentially expressed genes at the stationary phase, 32 (13.85%) and 199 (86.15%) genes were up- and down-regulated, respectively. Furthermore, results also indicated that genes coding for several COGs functions, especially in metabolism, signal-transduction, transcription, translation, chemotaxis, and cell motility, were down-regulated in response to microgravity stress, and therefore, the downregulation of genes seems to be the central mechanism for cells to cope under stimulated microgravity.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s12217-026-10245-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147560356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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