Potential of Interval Training Protocol on a Short-Arm Human Centrifuge for Orthostatic Intolerance Prevention After Space Flight Conditions

IF 1.3 4区工程技术 Q2 ENGINEERING, AEROSPACE

Microgravity Science and Technology Pub Date : 2025-05-10 DOI:10.1007/s12217-025-10180-w

Maria Vladimirovna Fedchuk, Vasily Borisovich Rusanov, Milena Ilinichna Koloteva, Anastasia Ivanovna Tersintseva, Alexey Vladimirovich Salnikov, Elena Sergeevna Luchitskaya, Galina Arkadyevna Fomina, Anna Grigorievna Chernikova

{"title":"Potential of Interval Training Protocol on a Short-Arm Human Centrifuge for Orthostatic Intolerance Prevention After Space Flight Conditions","authors":"Maria Vladimirovna Fedchuk, Vasily Borisovich Rusanov, Milena Ilinichna Koloteva, Anastasia Ivanovna Tersintseva, Alexey Vladimirovich Salnikov, Elena Sergeevna Luchitskaya, Galina Arkadyevna Fomina, Anna Grigorievna Chernikova","doi":"10.1007/s12217-025-10180-w","DOIUrl":null,"url":null,"abstract":"<div><p>The decrease in orthostatic tolerance due to the deconditioning of cardiovascular system after space flight remains an urgent problem. The effect of longitudinal overloads on a short-arm human centrifuge (SAHC) is believed to be useful in preventing a decrease in orthostatic tolerance in astronauts after spaceflight through regular compensation of hydrostatic blood pressure, which is absent in microgravity. The analysis of adaptive reactions of the autonomic regulation system was carried out by analyzing heart rate variability, blood pressure was used to calculate hemodynamic parameters. These characteristics were analyzed in 6 male subjects (mean age 38 ± 7 (SD) years) during the protocol of training rotations on the SAHC and during a passive orthostatic test with foot support (tilt test). The nonparametric Wilcoxon criterion and Kendall’s rank correlation coefficient were used for statistical analysis. During training rotations, an increase in heart rate (HR), a weakening of high-frequency (HF) and a significant increase in low-frequency (LF) spectral components of the heart rate were observed, indicating the involvement of the sympatho-vagal system with a predominance of sympathetic regulation. It is shown that after a series of rotations on the SAHC, there is a smaller increase in HR in an upright position during a tilt test, which indicates a decrease in excitability and reactivity of the sympathetic nervous system. There was also a decrease in the influence of suprasegmental (higher) autonomic centers on the regulation processes during orthostatic loading. This interval training protocol on the SAHC has a training effect and increases orthostatic stability.</p></div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"37 3","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microgravity Science and Technology","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s12217-025-10180-w","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, AEROSPACE","Score":null,"Total":0}

引用次数: 0

Abstract

The decrease in orthostatic tolerance due to the deconditioning of cardiovascular system after space flight remains an urgent problem. The effect of longitudinal overloads on a short-arm human centrifuge (SAHC) is believed to be useful in preventing a decrease in orthostatic tolerance in astronauts after spaceflight through regular compensation of hydrostatic blood pressure, which is absent in microgravity. The analysis of adaptive reactions of the autonomic regulation system was carried out by analyzing heart rate variability, blood pressure was used to calculate hemodynamic parameters. These characteristics were analyzed in 6 male subjects (mean age 38 ± 7 (SD) years) during the protocol of training rotations on the SAHC and during a passive orthostatic test with foot support (tilt test). The nonparametric Wilcoxon criterion and Kendall’s rank correlation coefficient were used for statistical analysis. During training rotations, an increase in heart rate (HR), a weakening of high-frequency (HF) and a significant increase in low-frequency (LF) spectral components of the heart rate were observed, indicating the involvement of the sympatho-vagal system with a predominance of sympathetic regulation. It is shown that after a series of rotations on the SAHC, there is a smaller increase in HR in an upright position during a tilt test, which indicates a decrease in excitability and reactivity of the sympathetic nervous system. There was also a decrease in the influence of suprasegmental (higher) autonomic centers on the regulation processes during orthostatic loading. This interval training protocol on the SAHC has a training effect and increases orthostatic stability.

查看原文本刊更多论文

短臂人体离心机间歇训练方案在太空飞行条件下预防直立不耐受的潜力

航天飞行后心血管系统的失调导致的直立耐受性下降是一个亟待解决的问题。纵向过载对短臂人体离心机（SAHC）的影响被认为有助于通过定期补偿流体静压来防止宇航员在航天飞行后直立耐受性的下降，这在微重力环境中是不存在的。通过心率变异性分析自主调节系统的适应性反应，血压计算血流动力学参数。我们分析了6名男性受试者（平均年龄38±7 （SD）岁）在SAHC旋转训练方案和有足部支撑的被动直立试验（倾斜试验）期间的这些特征。采用非参数Wilcoxon标准和Kendall等级相关系数进行统计分析。在旋转训练过程中，观察到心率（HR）增加，高频（HF）减弱，低频（LF）谱成分显著增加，表明交感神经迷走神经系统参与其中，交感神经调节占主导地位。结果表明，在SAHC上进行一系列旋转后，在倾斜测试中，直立位置的HR有较小的增加，这表明交感神经系统的兴奋性和反应性降低。在直立负荷过程中，超节段（更高）自主神经中枢对调节过程的影响也有所减弱。这种间歇训练方案具有训练效果，并增加直立稳定性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Microgravity Science and Technology 工程技术-工程：宇航

CiteScore

3.50

自引率

44.40%

发文量

期刊介绍： Microgravity Science and Technology – An International Journal for Microgravity and Space Exploration Related Research is a is a peer-reviewed scientific journal concerned with all topics, experimental as well as theoretical, related to research carried out under conditions of altered gravity. Microgravity Science and Technology publishes papers dealing with studies performed on and prepared for platforms that provide real microgravity conditions (such as drop towers, parabolic flights, sounding rockets, reentry capsules and orbiting platforms), and on ground-based facilities aiming to simulate microgravity conditions on earth (such as levitrons, clinostats, random positioning machines, bed rest facilities, and micro-scale or neutral buoyancy facilities) or providing artificial gravity conditions (such as centrifuges). Data from preparatory tests, hardware and instrumentation developments, lessons learnt as well as theoretical gravity-related considerations are welcome. Included science disciplines with gravity-related topics are: − materials science − fluid mechanics − process engineering − physics − chemistry − heat and mass transfer − gravitational biology − radiation biology − exobiology and astrobiology − human physiology