Microgravity Science and Technology最新文献

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GRS Ground-Based Short-Term Microgravity Test of “Taiji-1” Utilizing the µg0-Level Drop Tower Beijing “太极一号”利用微米级落塔进行的GRS地基短期微重力试验北京
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-21 DOI: 10.1007/s12217-026-10244-5
Laifu Chen, Shaoxin Wang, Kai Li, Jianfu Zhao, Heng Jiang, Zuolei Wang, Ziren Luo, Keqi Qi, Ruihong Gao
{"title":"GRS Ground-Based Short-Term Microgravity Test of “Taiji-1” Utilizing the µg0-Level Drop Tower Beijing","authors":"Laifu Chen,&nbsp;Shaoxin Wang,&nbsp;Kai Li,&nbsp;Jianfu Zhao,&nbsp;Heng Jiang,&nbsp;Zuolei Wang,&nbsp;Ziren Luo,&nbsp;Keqi Qi,&nbsp;Ruihong Gao","doi":"10.1007/s12217-026-10244-5","DOIUrl":"10.1007/s12217-026-10244-5","url":null,"abstract":"<div>\u0000 \u0000 <p>The drop tower facility generates a ground-based microgravity environment, functioning as a validation platform for a wide range of microgravity scientific experiments. To satisfy the ultra-low microgravity requirements for ground testing of the Gravitational Reference Sensor (GRS)—the core payload of the “Taiji-1” mission—a newly designed experimental capsule was developed for the Drop Tower Beijing (DTB). Using this capsule, successful tests were conducted on the GRS engineering model. Experimental results show that the Test Mass (TM) is stably captured during the effective microgravity period, achieving a control precision better than 1 × 10⁻⁶ <i>g</i>₀/Hz<sup>1/2</sup> across the 1–50 Hz frequency band. Collectively, these results validate both the capture and control performance of the GRS and the capability of the DTB with the newly designed dual-cell capsule to provide a µ<i>g</i><sub>0</sub>-level microgravity environment. This successful verification provides strong support for future scientific experiments demanding ultra-high microgravity level.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147560352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Rotation and Variable Viscosity on Convective Instability in a Navier–Stokes–Voigt Fluid Layer 旋转和变粘度对Navier-Stokes-Voigt流体层对流不稳定性的影响
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-16 DOI: 10.1007/s12217-025-10228-x
Dhananjay Yadav, Mukesh Kumar Awasthi, Ravi Ragoju, Raghunath Kodi, Amit Mahajan
{"title":"Influence of Rotation and Variable Viscosity on Convective Instability in a Navier–Stokes–Voigt Fluid Layer","authors":"Dhananjay Yadav,&nbsp;Mukesh Kumar Awasthi,&nbsp;Ravi Ragoju,&nbsp;Raghunath Kodi,&nbsp;Amit Mahajan","doi":"10.1007/s12217-025-10228-x","DOIUrl":"10.1007/s12217-025-10228-x","url":null,"abstract":"<div>\u0000 \u0000 <p>This investigation analyzes the effects of variable viscosity and rotation on the onset of thermal convection in a non-Newtonian Navier–Stokes–Voigt (NSV) fluid, which has not been addressed in the available literature. The threshold for convective instability is obtained by linearizing the governing equations related to the perturbations. The consequential eigenvalue problem is then solved both analytically and numerically through the Galerkin process. The necessity of the Kelvin-Voigt factor, the viscosity variation factor, the Taylor number and the Prandtl number on the critical stability parameters is exhaustively examined. It is detected that above the certain threshold assessment of the Taylor number, the instability creates in as oscillatory type. The threshold range of the Taylor number at which oscillatory motion probable enhances with increasing the viscosity variation factor while, it declines with increasing the Prandtl number. The stability of the arrangement increases with increasing the Taylor number and the Prandtl number whereas, it decreases with the viscosity variation factor and the Kelvin-Voigt factor. The dimension of the convective cells declines with increasing the Taylor number, the viscosity variation factor and the Prandtl number while, it upsurges with the Kelvin-Voigt factor if the value of the Prandtl number is more than one.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147559454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Simulated Microgravity on Osseointegration of Titanium Implants and the Interventional Role of Icariin Combined with Exercise 模拟微重力对钛种植体骨整合的影响及淫羊藿苷联合运动的介入作用
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-14 DOI: 10.1007/s12217-026-10243-6
Hong-zhi Zhou, Wen-tian Wang, An-qing Wang, Su-meng Shi, Yu-wei Zhang, Xue-ling Wang
{"title":"Effects of Simulated Microgravity on Osseointegration of Titanium Implants and the Interventional Role of Icariin Combined with Exercise","authors":"Hong-zhi Zhou,&nbsp;Wen-tian Wang,&nbsp;An-qing Wang,&nbsp;Su-meng Shi,&nbsp;Yu-wei Zhang,&nbsp;Xue-ling Wang","doi":"10.1007/s12217-026-10243-6","DOIUrl":"10.1007/s12217-026-10243-6","url":null,"abstract":"<div>\u0000 \u0000 <p>This study investigated the impact of simulated microgravity on titanium implant osseointegration and assessed the reparative efficacy of icariin (ICA) combined with treadmill exercise. Male Sprague–Dawley rats (<i>n</i> = 24) were divided into four groups: normal gravity control (CON), simulated microgravity (SMG), SMG + ICA, and SMG + ICA+treadmill exercise (SMG + ICA+EXER). SMG groups underwent tail suspension for four weeks, followed by ICA (25 mg/kg/day) and/or exercise interventions. Micro-CT, fluorochrome labeling, toluidine blue staining, and biomechanical tests were performed at week 8. Micro-CT analysis revealed that Groups SMG, SMG + ICA, and SMG + ICA+EXER exhibited a gradual increase in Tb.Th, Tb.BV/TV, DA, Tb.BMD, and Tb.BMC, and a gradual decrease in BS/BV, Tb.Sp, and SMI compared to Group CON, Mineral apposition rate (MAR) and bone-to-implant contact (BIC) were also significantly higher in ICA groups ( <i>P</i> &lt; 0.05 ), matching CON levels ( <i>P</i> &gt; 0.05 ). Biomechanical strength was enhanced in ICA groups, with superior performance in SMG + ICA+EXER. Simulated microgravity impairs osseointegration, but ICA mitigates these effects, with treadmill exercise further augmenting bone integration and biomechanical strength. This combined strategy may serve as a viable countermeasure for maintaining implant stability in space medicine.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s12217-026-10243-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147441923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of Heat Transfer in Solidification Experiments of Lightweight High-entropy Alloys on Chinese Space Station 中国空间站上轻质高熵合金凝固实验中的传热表征
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-10 DOI: 10.1007/s12217-025-10230-3
Pengfei Lu, Rui Liu, Lubin Wang, Qiang Yu
{"title":"Characterization of Heat Transfer in Solidification Experiments of Lightweight High-entropy Alloys on Chinese Space Station","authors":"Pengfei Lu,&nbsp;Rui Liu,&nbsp;Lubin Wang,&nbsp;Qiang Yu","doi":"10.1007/s12217-025-10230-3","DOIUrl":"10.1007/s12217-025-10230-3","url":null,"abstract":"<div>\u0000 \u0000 <p>Owing to the difference in convective heat transfer mechanisms between space and ground, the temperature profile of lightweight high-entropy alloys (HEAs) in space is different from the ground which may prevent the samples from melting as intended and thus cause the space experiment to fail. To predict the temperature profile and obtain the heat transfer characteristics in space, it employed experimental temperature data of the standard SCA at 800 °C under both ground and space. Specifically, numerical models of the high-temperature furnace and SCA were established, and different operating conditions and relevant thermophysical parameters were adjusted to conduct the thermal simulations of the temperature profile of the SCA in space and on ground. The respective heat transfer characteristics for space and ground were thus obtained. Based on the obtained heat transfer characteristics, the temperature profile and heat transfer characteristics of the lightweight HEA experiment in space were predicted when the furnace temperature is 900 °C, the target experimental temperature from the ground-based HEA experiment. The results provide an important foundation for conducting HEA solidification experiments in microgravity.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147441303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D Spatiotemporal Oscillation Characteristics of Nanofluids Thermocapillary Convection in Rectangular Cavity 矩形腔内纳米流体热毛细对流的三维时空振荡特性
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-09 DOI: 10.1007/s12217-025-10232-1
Yanni Jiang, Yuhang Zheng, Cheng Dai, Xiaoming Zhou
{"title":"3D Spatiotemporal Oscillation Characteristics of Nanofluids Thermocapillary Convection in Rectangular Cavity","authors":"Yanni Jiang,&nbsp;Yuhang Zheng,&nbsp;Cheng Dai,&nbsp;Xiaoming Zhou","doi":"10.1007/s12217-025-10232-1","DOIUrl":"10.1007/s12217-025-10232-1","url":null,"abstract":"<div><p>For disclose the 3D spatiotemporal oscillation characteristics of nanofluid thermocapillary convection, this paper numerically studies the supercritical oscillatory process of nanofluids thermocapillary convection in a 3D rectangular cavity under microgravity conditions, and the propagation characteristics of flow field and temperature waves are analyzed. The results show that, under supercritical condition the flow field is composed of multiple dynamically migrating convective vortices, and the periodic temperature waves not only appear at free surface, but also inside the liquid layer. With increasing nanoparticle volume fraction, both the dominant frequency and amplitude of velocity oscillation exhibit linear reduction, while the oscillation period increases linearly. Furthermore, the propagation angle of hydrothermal waves increases progressively with nanoparticles volume fraction increasing, particularly, the angle from 27.5° increases to 33° as nanoparticles volume fraction varies from 0 to 0.05.</p></div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147440929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concentration-Induced Convection in Reactive Wetting of Al–Mg-Mn Alloys by Zn-based Solders under Variable Gravity 变重力下zn基钎料反应润湿Al-Mg-Mn合金的浓度诱导对流
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-03-07 DOI: 10.1007/s12217-026-10237-4
Svetlana A. Gruzd, Ilya R. Saltykov, Ilya V. Shutov, Dmitry S. Samsonov, Mikhail D. Krivilyov
{"title":"Concentration-Induced Convection in Reactive Wetting of Al–Mg-Mn Alloys by Zn-based Solders under Variable Gravity","authors":"Svetlana A. Gruzd,&nbsp;Ilya R. Saltykov,&nbsp;Ilya V. Shutov,&nbsp;Dmitry S. Samsonov,&nbsp;Mikhail D. Krivilyov","doi":"10.1007/s12217-026-10237-4","DOIUrl":"10.1007/s12217-026-10237-4","url":null,"abstract":"<div><p>Brazing of aluminum alloys using chemically active fillers is in demand in transportation and aerospace engineering for the development of new techniques suitable under microgravity conditions for outer space repair. This work presents a theoretical study of diffusion and hydrodynamic flows in molten Zn solder during the reactive wetting of an Al–Mg-Mn plate under various gravity conditions. The model is developed in the isothermal formulation at different wetting temperatures, considering the concentration-driven effect in the soldered zone. The influence of Marangoni convection caused by the Zn concentration gradient on the flow structure and erosion of the base material is analyzed. The effect of zinc evaporation during reactive wetting under vacuum conditions is revealed and quantitatively described. The dependency of the Zn solder droplet radius during its spreading on a flat Al–Mg-Mn plate under various external conditions is also analyzed.</p></div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147363364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunological and Hormonal Changes During a 25‑h Shallow‑Water Immersion: a Two‑Case Report 免疫和激素的变化在25小时的浅水浸泡:两例报告
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-02-28 DOI: 10.1007/s12217-026-10236-5
Luca Bonanni, Gino Chioetto, Nicola Ferri
{"title":"Immunological and Hormonal Changes During a 25‑h Shallow‑Water Immersion: a Two‑Case Report","authors":"Luca Bonanni,&nbsp;Gino Chioetto,&nbsp;Nicola Ferri","doi":"10.1007/s12217-026-10236-5","DOIUrl":"10.1007/s12217-026-10236-5","url":null,"abstract":"<div>\u0000 \u0000 <p>Prolonged immersion in thermoneutral water reproduces several physiological adaptations of orbital flight but its endocrine‑immune consequences remain incompletely characterised. We investigated stress hormones and immune markers in two healthy divers undergoing a 25‑h shallow‑water immersion and compared the findings with contemporary microgravity literature. Peripheral blood was collected one day before and &lt; 15 min after immersion. Flow cytometry, 51Cr‑release assay, lymphocyte proliferation, intracellular cytokine PCR and routine endocrinology panels were performed. All data were corrected for plasma‑volume shifts. Cortisol, growth hormone and prolactin increased by 45–100%, whereas testosterone declined modestly. CD56⁺ natural killer (NK)‑cell frequency fell (‑25% and ‑32%) without loss of cytotoxicity. PBMC proliferation in response to phytohaemagglutinin decreased (‑30% to ‑45%). A Th1 → Th2 cytokine shift was evident with lower IFN‑γ and higher IL‑4 expression. These responses mirror patterns reported after head‑down bed rest and long‑duration spaceflight. Extended shallow‑water immersion is sufficient to activate the neuro‑endocrine stress axis and induce selective, microgravity‑like immune alterations. Thermoneutral immersion may therefore serve as a cost‑effective analogue for mechanistic studies and countermeasure testing.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147342432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microhemodynamic Adjustments and the Type of Autonomic Regulation Under Analog Long-term Isolation Conditions 模拟长期隔离条件下的微血流动力学调节和自主调节类型
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-02-28 DOI: 10.1007/s12217-026-10241-8
D. V. Pashkova, O. V. Popova, J. A. Popova, Yu I. Loktionova, E. V. Zharkikh, V. V. Sidorov, A. V. Dunaev, V. B. Rusanov
{"title":"Microhemodynamic Adjustments and the Type of Autonomic Regulation Under Analog Long-term Isolation Conditions","authors":"D. V. Pashkova,&nbsp;O. V. Popova,&nbsp;J. A. Popova,&nbsp;Yu I. Loktionova,&nbsp;E. V. Zharkikh,&nbsp;V. V. Sidorov,&nbsp;A. V. Dunaev,&nbsp;V. B. Rusanov","doi":"10.1007/s12217-026-10241-8","DOIUrl":"10.1007/s12217-026-10241-8","url":null,"abstract":"<div>\u0000 \u0000 <p>This study focused on microhemodynamic and autonomic regulation changes during long-term isolation in a 366-day SIRIUS-23 experiment with 6 healthy volunteers (2 men and 4 women, aged 25–37 years). Heart rate variability analysis and laser Doppler flowmetry were used to assess cardiovascular system responses before, during, and after isolation. Volunteers demonstrated distinct autonomic regulation patterns, dividing into two groups based on vagal tone and vascular center activity. Group 2 showed consistently higher autonomic function throughout the experiment. Microcirculation parameters revealed decreased perfusion in the forehead area for Group 1 and fluctuating dynamics for Group 2. Both groups exhibited endothelial tone reduction and altered blood flow distribution in the toe area with increased shunt flow. Prolonged isolation significantly affects microhemodynamics and autonomic regulation. Individuals with higher vagal tone demonstrated better adaptation. These findings contribute to understanding physiological responses to long-term confinement and have implications for space mission medical support.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147342431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental Investigation of Diamagnetic Fluids With Magnetically Compensated Effective Gravity 具有磁补偿有效重力的抗磁性流体实验研究
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-02-27 DOI: 10.1007/s12217-025-10234-z
Shifeng Lin, Xu Zhang, Shensen Feng, Huiying Wu, Zhenyu Liu, Zhen Fang, Chuanying Xi, ShengXian Huang
{"title":"Experimental Investigation of Diamagnetic Fluids With Magnetically Compensated Effective Gravity","authors":"Shifeng Lin,&nbsp;Xu Zhang,&nbsp;Shensen Feng,&nbsp;Huiying Wu,&nbsp;Zhenyu Liu,&nbsp;Zhen Fang,&nbsp;Chuanying Xi,&nbsp;ShengXian Huang","doi":"10.1007/s12217-025-10234-z","DOIUrl":"10.1007/s12217-025-10234-z","url":null,"abstract":"<div><p>Fluid flow and phase-change processes under variable-gravity are of significant scientific interest in space science, thermal control engineering and planetary exploration. However, current variable and micro-gravity experiments mainly rely on space stations or parabolic flights, which are limited by short experimental durations, high costs, and restricted repeatability. To overcome these limitations, this study develops a ground-based experimental approach on diamagnetic levitation. Deionized water is adopted as the working fluid in a strong magnetic field to conduct representative variable-gravity experiments, including single-droplet levitation, liquid bridge formation, capillary flow, and boiling. The experimental results show that: in the single-droplet levitation experiment, stable levitation can be achieved when the central magnetic field reached 23.28 T. In the capillary rise experiment under typical gravity conditions, the maximum deviation between the measured liquid height and the theoretical prediction is 5.25%. In the liquid bridge experiment, the difference between the measured maximum diameter and the theoretical prediction is only 0.07 mm. In the boiling experiment, distinct boiling behaviors are successfully observed under different effective gravity levels. It can also be used to construct simulated gravity experimental conditions on the surfaces of planets such as the Moon and Mars. These results demonstrate that the proposed experimental approach enables stable, long-duration, high-precision, and cost-effective simulation of micro/reduced-gravity environments. This work establishes a ground-based diamagnetic gravity-compensation facility that enables controlled studies of fluid flow and phase-change heat transfer in diamagnetic fluids under magnetically compensated effective gravity conditions, offering valuable insights for space and planetary thermal-fluid applications.</p></div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147342519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in Non-Invasive Intracranial Pressure Monitoring for Spaceflight-Associated Neuro-Ocular Syndrome and their Implications for Neurological Monitoring 航天相关神经-眼综合征无创颅内压监测进展及其对神经系统监测的意义
IF 1.3 4区 工程技术
Microgravity Science and Technology Pub Date : 2026-02-26 DOI: 10.1007/s12217-026-10238-3
Rahul Kumar, Kyle Sporn, Saif Pasha, Phani Paladugu, Ethan Waisberg, Joshua Ong, Alireza Tavakkoli
{"title":"Advancements in Non-Invasive Intracranial Pressure Monitoring for Spaceflight-Associated Neuro-Ocular Syndrome and their Implications for Neurological Monitoring","authors":"Rahul Kumar,&nbsp;Kyle Sporn,&nbsp;Saif Pasha,&nbsp;Phani Paladugu,&nbsp;Ethan Waisberg,&nbsp;Joshua Ong,&nbsp;Alireza Tavakkoli","doi":"10.1007/s12217-026-10238-3","DOIUrl":"10.1007/s12217-026-10238-3","url":null,"abstract":"<div>\u0000 \u0000 <p>Long-duration spaceflight has revealed a distinctive constellation of neuro-ocular abnormalities, collectively known as Spaceflight-Associated Neuro-Ocular Syndrome (SANS). These are hypothesized to result from cephalad fluid shifts in microgravity, leading to altered cerebrovascular dynamics and suspected mild elevations in intracranial pressure (ICP). Invasive ICP monitoring techniques are unsuitable for spaceflight, prompting the development and validation of non-invasive alternatives, including optic nerve sheath diameter (ONSD) ultrasound and transcranial Doppler (TCD), which offer practical and reliable surrogates for estimating ICP. When combined, these methods can improve diagnostic accuracy and enable multimodal neuromonitoring. Integration of rapidly advancing artificial intelligence (AI) models into ONSD and TCD systems can further enhance precision, reduce operator dependence, and enable automated trend analysis. This paper examines current advances in non-invasive ICP monitoring within space medicine, evaluates their readiness for operational deployment, and identifies key challenges related to standardization, calibration, and validation. These breakthroughs hold substantial promise for supporting astronaut health during spaceflight and planetary missions, while also advancing neurocritical care on Earth.</p>\u0000 </div>","PeriodicalId":707,"journal":{"name":"Microgravity Science and Technology","volume":"38 2","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147342108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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