Acta physiologica Academiae Scientiarum Hungaricae最新文献

Modification of the cytoprotective effect of prostacyclin on gastric epithelial cells of rats by colchicine. 秋水仙碱修饰前列环素对大鼠胃上皮细胞的细胞保护作用。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

G Karácsony, G A Bálint, G Lukács, V Varró

引用次数: 0

Effect of verapamil and phenoxybenzamine on nickel-induced coronary vasoconstriction in the anaesthetized dog. 维拉帕米和苯氧苄胺对镍致麻醉犬冠状动脉收缩的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

A Koller, G Rubányi, L Ligeti, A G Kovách

引用次数: 0

New theory of the development of myocardial infarction. 心肌梗塞发展的新理论。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

M Szentiványi, C Vértesi, A Paál, M Pénzes, G P Leszkovszky, B Balázs, C Kiss

{"title":"New theory of the development of myocardial infarction.","authors":"M Szentiványi, C Vértesi, A Paál, M Pénzes, G P Leszkovszky, B Balázs, C Kiss","doi":"","DOIUrl":"","url":null,"abstract":"Solutions of KCl (1%, 10% and 31.2%) administered into the pericardial fluid or applied onto the surface of the heart evoked a dome-like change of the ECG in dogs, rats and guinea-pigs and led to myocardial infarction in 3-5 days. Both the acute changes in ECG and the infarction itself could be prevented by the application of pericardial fluid samples and by administration of three synthetic compounds onto the heart surface. The same substances also inhibited the development of ECG changes elicited by general hypoxia due to stopping artificial respiration. The existence of a peculiar myocardial space beginning with outer pores and reaching the myocardial cells through connective tissue pathways is postulated. Earlier studies showed that 125I-labelled albumin applied to the epicardial surface through a filter paper reached the endomyocardium through some intramyocardial pathways beginning with epicardial pores. In the present experiments intrapericardial application of India ink led to obstruction of these pores and thus prevented the infarction elicited by intrapericardial administration of KCl solutions. This space, being distinct from that accessible from the coronary arteries, serves for transfer of various substances into the myocardium, while other compounds (e.g. noradrenaline) are not effective through this pathway. Oxygen reaching this space from the epicardial surface protects the myocardium from the damaging effects of hypoxia and KCl.","PeriodicalId":7049,"journal":{"name":"Acta physiologica Academiae Scientiarum Hungaricae","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18181739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurotoxicological investigation of the new Hungarian pesticide Toxurazine. 匈牙利新农药脲嗪的神经毒理学研究。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

I Dési, J Szlobodnyik, M Karmos-Várszegi, A Strohmayer, G Bakó

引用次数: 0

Distinct effect of contraction and ion transport on NADH fluorescence and lactate production in uterine smooth muscle. 收缩和离子转运对子宫平滑肌NADH荧光和乳酸生成的明显影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

G Rubányi, A Tóth, A G Kovách

{"title":"Distinct effect of contraction and ion transport on NADH fluorescence and lactate production in uterine smooth muscle.","authors":"G Rubányi, A Tóth, A G Kovách","doi":"","DOIUrl":"","url":null,"abstract":"The present studies were designed to monitor metabolic perturbations following changes in contractile activity and ion transport in rat and rabbit myometrium by simultaneous measurement of NADH fluorescence, lactate production and isometric force. Stimulation (127 mM K+) and inhibition (Ca2+-deficient solution) of isometric force development induced a decrease/increase of fluorescence intensity corresponding to a more oxidized/reduced state of tissue pyridine nucleotides, respectively. If tension development was abolished by EGTA, fluorescence changes due to altered ion transport could be monitored. Slow progressive stimulation of the sodium pump by Ca2++-deficient solution resulted in an ouabain (10(-3) M) sensitive monophasic NADH oxidation, which was reversed by inhibition of the pump by isotonic K+ solution. If, however, stimulation of the pump was rapid and maximal (addition of 30 mM KCl to Na+-loaded tissues) the fluorescence response was triphasic and ouabain sensitive: it consisted of an initial NAD reduction followed by a transient NADH oxidation and a second slow NAD reduction. These fluorescence changes are interpreted in terms of separate redox changes in the cytoplasm and mitochondria. The ouabain sensitive stimulation or inhibition of Na/K transport was always accompanied by parallel changes in uterine lactate production irrespective of the actual contractile state of the myometrium. The present results show that 1 fluorescence technique can be applied to monitor metabolic perturbations in the uterus evoked by changes in contractility or ion transport; and 2 aerobic glycolysis and Na/K transport are tightly coupled in the myometrium.","PeriodicalId":7049,"journal":{"name":"Acta physiologica Academiae Scientiarum Hungaricae","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18194744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demonstration of Fc and C3b receptors on rat perikarya. 大鼠核周Fc和C3b受体的证实。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

A Perl, B Fekete, P Gergely, A G Kovách

引用次数: 0

Influence of augmentation of excretory renal mass on renal function after alpha-receptor blockade. α受体阻断后排泄性肾块增大对肾功能的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

H Tost, R Herceg, G Kövér

{"title":"Influence of augmentation of excretory renal mass on renal function after alpha-receptor blockade.","authors":"H Tost, R Herceg, G Kövér","doi":"","DOIUrl":"","url":null,"abstract":"The effect of renal function of an augmentation of the excretory renal mass was investigated in 10 dogs without drug treatment and in 10 animals with alpha-receptor blockade. In the untreated group, augmentation of excretory renal mass by transplantation into the neck of one pair of kidneys isolated from another animal caused the following changes in the kidneys in situ: marked elevation in CPAH, slight decrease in Cinulin, slight diminution of urine excretion and a pronounced fall in sodium excretion. The amount of urine and sodium excreted by the four kidneys was identical with that previously excreted by the two kidneys in situ. In animals with alpha-receptor blockade, augmentation of the excretory renal mass had the following consequences in the in situ kidneys, CPAH, and Cinulin remained unchanged while urine and sodium excretion decreased to the same extent as in the untreated control group. The amount of urine and of sodium excreted by the four kidneys was the same as that excreted by the kidneys in situ, prior to transplantation of isolated kidneys, i.e. before the augmentation of excretory renal mass. It seems that the decrease in sodium excretion of the kidneys in situ was not due to the haemodynamic changes evoked by the load on the circulation; it was rather consequence of some quick, presumably humoral, regulation. The diminution of sodium excretion in the kidneys in situ after augmentation of the excretory renal mass has been ascribed to an increased utilization by the four kidneys of the natriuretic factor(s), i.e. to a diminution in the plasma level of the natriuretic hormone.","PeriodicalId":7049,"journal":{"name":"Acta physiologica Academiae Scientiarum Hungaricae","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17196614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Steric mapping of some prostaglandin receptor sites. 一些前列腺素受体位置的立体定位。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

Z Simon, F Kerek

引用次数: 0

Relationship between the tissue redox state potential and dak/dt changes of [K+]0 activity during k-strophantoside or acetylcholine induced contractures. K -芪甲苷或乙酰胆碱诱导收缩时组织氧化还原态电位与[K+]0活性变化的关系

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

I Wittmann, A Puppi, M Dely

引用次数: 0

Effect of progesterone, testosterone and oestrogens on the plasma corticosterone and thyroid hormone concentrations in the female Japanese quail. 孕酮、睾酮和雌激素对雌性日本鹌鹑血浆皮质酮和甲状腺激素浓度的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1982-01-01

G Pethes, P Péczely

引用次数: 0