Acta medica Okayama最新文献_第4页

Lower Work Engagement Is Associated with Insomnia, Psychological Distress, and Neck Pain among Junior and Senior High School Teachers in Japan. 日本初中和高中教师中较低的工作投入与失眠、心理困扰和颈部疼痛有关。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68647

Rina Tsuchie, Mari Fukuda, Hideki Tsumura, Minako Kinuta, Takashi Hisamatsu, Hideyuki Kanda

{"title":"Lower Work Engagement Is Associated with Insomnia, Psychological Distress, and Neck Pain among Junior and Senior High School Teachers in Japan.","authors":"Rina Tsuchie, Mari Fukuda, Hideki Tsumura, Minako Kinuta, Takashi Hisamatsu, Hideyuki Kanda","doi":"10.18926/AMO/68647","DOIUrl":"https://doi.org/10.18926/AMO/68647","url":null,"abstract":"School teachers are subject to both physical and mental health problems. We examined cross-sectional relationships between work engagement and major health outcomes among junior and senior high school teachers in Japan via a nationwide survey in 2019-2020. A total of 3,160 respondents were included in the analyses (19.9% response rate). Work engagement was assessed with the Utrecht Work Engagement Scale-9 (UWES-9), and we thus divided the teachers into quartiles according to their UWES-9 scores. Based on validated questionnaires, we assessed insomnia, psychological distress, and neck pain as health outcomes. A binomial logistic regression adjusted for age, gender, school type, teacher's roles, involvement in club activities, division of duties, employment status, and whether they lived with family demonstrated that the teachers with lower UWES-9 scores had higher burdens of insomnia, psychological distress, and neck pain (odds ratios [95% confidence intervals] in 4th vs. 1st quartile, 2.92 (2.34-3.65), 3.70 (2.81-4.88), and 2.12 (1.68-2.68), respectively; all trend p<0.001). There were no significant differences in these associations between full-time and part-time teachers. Our findings indicate that low work engagement may contribute to physical and mental health issues among junior and senior high school teachers, thus providing insights for preventing health problems in this profession.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 2","pages":"93-100"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between Personality Traits and Postpartum Depressive Symptoms in Women who Became Pregnant via Infertility Treatment. 不孕症治疗孕妇人格特征与产后抑郁症状的关系

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68649

Kyoko Awai, Mikiya Nakatsuka

{"title":"Relationship between Personality Traits and Postpartum Depressive Symptoms in Women who Became Pregnant via Infertility Treatment.","authors":"Kyoko Awai, Mikiya Nakatsuka","doi":"10.18926/AMO/68649","DOIUrl":"https://doi.org/10.18926/AMO/68649","url":null,"abstract":"The status of postpartum depression was elucidated herein with the use of the Edinburgh Postnatal Depression Scale (EPDS) in women in Shikoku, Japan who became pregnant and gave birth after undergoing infertility treatment, including assisted reproductive technology (ART). The assessment was performed during their children's 4-month health examination. The relationships between postpartum depression and the mothers' background factors and scores on the Big Five personality traits scale were also examined. Of the Big Five personality traits, the scores for neuroticism were significantly higher in the ART group (n=71) than in the general infertility treatment (n=118) and natural pregnancy (n=872) groups. No significant differences in EPDS scores were seen among these three groups. A logistic regression analysis showed that neuroticism was associated with an EPDS score ≧9 points, (which is suggestive of postpartum depression, ) in all groups. Moreover, although a long-standing marriage had an inhibitory effect on postpartum depression in the natural pregnancy group, no such trend was seen in the ART group, which included many women with long-standing marriages. Particularly for women who become pregnant by ART, an individualized response that pays close attention to the woman's personality traits is needed.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 2","pages":"109-116"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between the Pretreatment Body Mass Index and Anamorelin's Efficacy in Patients with Cancer Cachexia: A Retrospective Cohort Study. 预处理体重指数与阿纳莫瑞林治疗癌症恶病质疗效的相关性：一项回顾性队列研究。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68644

Masatoshi Maki, Ryo Takada, Tomoyuki Ishigo, Miki Fujiwara, Yoko Takahashi, Shinya Otsuka, Koji Tamura, Terutaka Hamaoka

{"title":"Association between the Pretreatment Body Mass Index and Anamorelin's Efficacy in Patients with Cancer Cachexia: A Retrospective Cohort Study.","authors":"Masatoshi Maki, Ryo Takada, Tomoyuki Ishigo, Miki Fujiwara, Yoko Takahashi, Shinya Otsuka, Koji Tamura, Terutaka Hamaoka","doi":"10.18926/AMO/68644","DOIUrl":"https://doi.org/10.18926/AMO/68644","url":null,"abstract":"Anamorelin (ANAM) is used to treat cancer-associated cachexia, a syndrome involving muscle loss and anorexia. The timing of the initiation of ANAM treatment is crucial to its efficacy. Although the body mass index (BMI) is a diagnostic criterion for cancer cachexia, no studies have explored its association with ANAM efficacy. We conducted a single-center, retrospective cohort study to investigate the association between the pre-treatment BMI and ANAM efficacy in patients with cancer-associated cachexia (n=47). The ANAM treatment was considered effective if the patient's appetite improved within 30 days of treatment initiation. We calculated a BMI cutoff value (19.5 kg/m2) and used it to divide the patients into high- and low-BMI groups. Their background, clinical laboratory values, cancer types, and treatment lines were investigated. Twenty (42.6%) had a high BMI (≥ 19.5 kg/m2) and 27 (57.4%) had a low BMI (< 19.5 kg/m2). High BMI was significantly associated with ANAM effectiveness (odds ratio 7.86, 95% confidence interval 1.99-31.00, p=0.003). Together these results indicate that it is beneficial to initiate ANAM treatment before a patient's BMI drops below 19.5 kg/m2. Our findings will help advance cancer cachexia treatment and serve as a reference for clinicians to predict ANAM's efficacy.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 2","pages":"65-73"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Outcomes of Neoadjuvant Paclitaxel/Cisplatin/Gemcitabine Compared with Gemcitabine/Cisplatin for Muscle-Invasive Bladder Cancer. 新辅助紫杉醇/顺铂/吉西他滨与吉西他滨/顺铂治疗肌肉浸润性膀胱癌的临床效果比较

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68646

Tatsushi Kawada, Yasuyuki Kobayashi, Takuji Tsugawa, Kazuma Tsuboi, Satoshi Katayama, Takehiro Iwata, Kensuke Bekku, Tomoko Kobayashi, Kohei Edamura, Shin Ebara, Motoo Araki

{"title":"Clinical Outcomes of Neoadjuvant Paclitaxel/Cisplatin/Gemcitabine Compared with Gemcitabine/Cisplatin for Muscle-Invasive Bladder Cancer.","authors":"Tatsushi Kawada, Yasuyuki Kobayashi, Takuji Tsugawa, Kazuma Tsuboi, Satoshi Katayama, Takehiro Iwata, Kensuke Bekku, Tomoko Kobayashi, Kohei Edamura, Shin Ebara, Motoo Araki","doi":"10.18926/AMO/68646","DOIUrl":"https://doi.org/10.18926/AMO/68646","url":null,"abstract":"We retrospectively evaluated the oncologic outcomes of paclitaxel, cisplatin, and gemcitabine (PCG) with those of gemcitabine and cisplatin (GC) as neoadjuvant chemotherapy in muscle-invasive bladder cancer (MIBC) patients. The primary outcome was efficacy: pathological complete response (pCR), ypT0N0; and pathological objective response (pOR), ypT0N0, ≤ ypT1N0, or ypT0N1. Secondary outcomes included overall survival (OS), recurrence-free survival (RFS), predictive factors for pOR, OS, and RFS, and hematologic adverse events (AEs). Among 113 patients treated (PCG, n=28; GC, n=85), similar pOR and pCR rates were achieved by the groups (pOR: PCG, 57.1% vs. GC, 49. 4%; p=0.52; pCR: PCG, 39.3% vs. GC, 29.4%; p=0.36). No significant differences were observed in OS (p=1.0) or RFS (p=0.20). Multivariate logistic regression analysis showed that hydronephrosis (odds ratio [OR] 0.32, 95%CI: 0.11-0.92) and clinical node-positive status (cN+) (OR 0.22, 95%CI: 0.050-0.99) were significantly associated with a decreased probability of pOR. On multivariate Cox regression analyses, pOR achievement was associated with improved OS (hazard ratio [HR] 0.23, 95%CI: 0.10-0.56) and RFS (HR 0.30, 95%CI: 0.13-0.67). There were no significant between-group differences in the incidence of grade ≥ 3 hematologic AEs or dose-reduction required, but the PCG group had a higher incidence of grade 4 neutropenia.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 2","pages":"81-92"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macular Hole Formation Six Months after Hemorrhage Displacement for Submacular and Henle Fiber Layer Hemorrhage due to Retinal Arterial Macroaneurysm Rupture. 视网膜大动脉瘤破裂致黄斑下及亨勒纤维层出血后6个月黄斑裂孔的形成。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68651

Riku Akatsuka, Shuhei Kimura, Ryo Matoba, Mio Morizane Hosokawa, Yusuke Shiode, Tetsuro Morita, Shinichiro Doi, Yuki Morizane

引用次数: 0

Photoinitiators Induce Histamine Production in Human Mast Cells. 光引发剂诱导人肥大细胞产生组胺。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-02-01 DOI: 10.18926/AMO/68362

Taro Miura, Yoichi Kawasaki, Hirofumi Hamano, Yoshito Zamami, Toshiaki Sendo

引用次数: 0

A Rare Case of Compression Neuritis due to Intraorbital Arteriovenous Fistula (IOAVF) Mimicking Retrobulbar Optic Neuritis. 眶内动静脉瘘致压迫性神经炎1例，模拟球后视神经炎。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-02-01 DOI: 10.18926/AMO/68363

Shun Minakawa, Masayuki Hirano, Kazuya Takahashi, Yuta Imamura, Takashi Watanabe

引用次数: 0

Gastrectomy Causes an Imbalance in the Trunk Muscles. 胃切除术导致躯干肌肉不平衡。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-02-01 DOI: 10.18926/AMO/68354

Nanami Ikeya, Atsushi Okita, Shinsuke Hashida, Sumiharu Yamamoto, Hirokuni Ikeda, Kazunori Tsukuda, Shinichi Toyooka

{"title":"Gastrectomy Causes an Imbalance in the Trunk Muscles.","authors":"Nanami Ikeya, Atsushi Okita, Shinsuke Hashida, Sumiharu Yamamoto, Hirokuni Ikeda, Kazunori Tsukuda, Shinichi Toyooka","doi":"10.18926/AMO/68354","DOIUrl":"10.18926/AMO/68354","url":null,"abstract":"Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 1","pages":"9-19"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immediate Effects of a Single Home-based Rehabilitation Treatment on Balance Performance and Toe-Grip Strength in Elderly Subjects Continuing the Same Rehabilitation Program. 单次家庭康复治疗对继续进行相同康复计划的老年人平衡能力和脚趾握力的直接影响。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-02-01 DOI: 10.18926/AMO/68361

Kazunori Kojima, Takuya Ujikawa, Toshiro Ono

引用次数: 0

Prediction of Prostate Cancer Grades Using Radiomic Features. 利用放射学特征预测前列腺癌分级。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-02-01 DOI: 10.18926/AMO/68355

Yasuhiro Yamamoto, Takafumi Haraguchi, Kaori Matsuda, Yoshio Okazaki, Shin Kimoto, Nozomu Tanji, Atsushi Matsumoto, Yasuyuki Kobayashi, Hidefumi Mimura, Takao Hiraki

{"title":"Prediction of Prostate Cancer Grades Using Radiomic Features.","authors":"Yasuhiro Yamamoto, Takafumi Haraguchi, Kaori Matsuda, Yoshio Okazaki, Shin Kimoto, Nozomu Tanji, Atsushi Matsumoto, Yasuyuki Kobayashi, Hidefumi Mimura, Takao Hiraki","doi":"10.18926/AMO/68355","DOIUrl":"10.18926/AMO/68355","url":null,"abstract":"We developed a machine learning model for predicting prostate cancer (PCa) grades using radiomic features of magnetic resonance imaging. 112 patients diagnosed with PCa based on prostate biopsy between January 2014 and December 2021 were evaluated. Logistic regression was used to construct two prediction models, one using radiomic features and prostate-specific antigen (PSA) values (Radiomics model) and the other Prostate Imaging-Reporting and Data System (PI-RADS) scores and PSA values (PI-RADS model), to differentiate high-grade (Gleason score [GS] ≥ 8) from intermediate or low-grade (GS < 8) PCa. Five imaging features were selected for the Radiomics model using the Gini coefficient. Model performance was evaluated using AUC, sensitivity, and specificity. The models were compared by leave-one-out cross-validation with Ridge regularization. Furthermore, the Radiomics model was evaluated using the holdout method and represented by a nomogram. The AUC of the Radiomics and PI-RADS models differed significantly (0.799, 95% CI: 0.712-0.869; and 0.710, 95% CI: 0.617-0.792, respectively). Using holdout method, the Radiomics model yielded AUC of 0.778 (95% CI: 0.552-0.925), sensitivity of 0.769, and specificity of 0.778. It outperformed the PI-RADS model and could be useful in predicting PCa grades, potentially aiding in determining appropriate treatment approaches in PCa patients.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 1","pages":"21-30"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0