Acta medica Okayama最新文献_第4页

Spontaneous Bilateral Pneumothorax in a Patient with Anorexia Nervosa: The Management of Prolonged Postoperative Air Leakage. 厌食症患者自发性双侧气胸：术后长期漏气的处理。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67203

Kazuhiro Okada, Yuho Maki, Kei Matsubara, Yutaka Hirano, Toshiya Fujiwara, Motoki Matsuura

引用次数: 0

Effect of Humidified High-Flow Nasal Cannula Oxygen Therapy with a Pulmonary Infection Control Window as a Ventilation Switching Indication in Combination with Atomizing Inhalation of Terbutaline on the Lung Function of Patients with Acute Exacerbation of COPD. 以肺部感染控制窗口作为通气切换指征的湿化高流量鼻导管供氧疗法与雾化吸入特布他林联合疗法对慢性阻塞性肺疾病急性加重患者肺功能的影响

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67202

Mengjiao Ye, Renwei Zhang

{"title":"Effect of Humidified High-Flow Nasal Cannula Oxygen Therapy with a Pulmonary Infection Control Window as a Ventilation Switching Indication in Combination with Atomizing Inhalation of Terbutaline on the Lung Function of Patients with Acute Exacerbation of COPD.","authors":"Mengjiao Ye, Renwei Zhang","doi":"10.18926/AMO/67202","DOIUrl":"10.18926/AMO/67202","url":null,"abstract":"We investigated how humidified high-flow nasal cannula oxygen therapy (HFNC) with a pulmonary infection control (PIC) window as a ventilation switching indication in combination with atomizing inhalation of terbutaline affects the lung function of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We examined 140 hospitalized AECOPD patients randomized to control and observation groups. Conventional supportive therapy and invasive mechanical ventilation with tracheal intubation were conducted in both groups, with a PIC window as the indication for ventilation switching. Noninvasive positive pressure ventilation (NIPPV) plus atomizing inhalation of terbutaline was used in the control group. In the observation group, HFNC combined with atomizing inhalation of terbutaline was used. Compared to the control group, after 48-hr treatment and treatment completion, the observation group had significantly increased levels of lung function indicators (maximal voluntary ventilation [MVV] plus forced vital capacity [FVC], p<0.05) and oxygen metabolism indicators (arterial oxygen partial pressure [PaO2], arterial oxygen content [CaO2], and oxygenation index, p<0.05). The comparison of the groups revealed that the levels of airway remodeling indicators (matrix metalloproteinase-2 [MMP-2], tissue inhibitor of metalloproteinase 2 [TIMP-2] plus MMP-9) and inflammatory indicators (interferon gamma [IFN-γ] together with interleukin-17 [IL-17], IL-10 and IL-4) were significantly lower after 48 h of treatment as well as after treatment completion (both p<0.05). These results demonstrate that HFNC with a PIC window as the indication for ventilation switching combined with atomizing inhalation of terbutaline can relieve the disorder of oxygen metabolism and correct airway hyper-reactivity.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"271-279"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcification of a Hydrophilic Acrylic Intraocular Lens after Glaucoma Surgery. 青光眼手术后亲水性丙烯酸眼内透镜的钙化。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67206

Sara Okamoto, Yusuke Shiode, Shuhei Kimura, Mio Hosokawa, Ryo Matoba, Yuki Kanzaki, Hiroya Kindo, Tetsuro Morita, Akihiro Tsuji, Kosuke Takahashi, Yuki Morizane

引用次数: 0

Palliative Gamma Knife Radiosurgery for a Small Part of a Large Vestibular Schwannoma in an Elderly Patient. 姑息性伽玛刀放射外科手术治疗老年患者的小部分大前庭许旺瘤

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67207

Kiyoshi Nakazaki, Satoshi Hirai, Tomohito Hishikawa

引用次数: 0

Assessment of a New Elbow Joint Positioning Method Using Area Detector Computed Tomography. 利用区域探测器计算机断层扫描评估新的肘关节定位方法

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67196

Takuya Akagawa, Ryohei Fukui, Katsuhiro Kida, Ryutaro Matsuura, Makoto Shimada, Mitsuhiro Kinoshita, Yoko Akagawa, Sachiko Goto

{"title":"Assessment of a New Elbow Joint Positioning Method Using Area Detector Computed Tomography.","authors":"Takuya Akagawa, Ryohei Fukui, Katsuhiro Kida, Ryutaro Matsuura, Makoto Shimada, Mitsuhiro Kinoshita, Yoko Akagawa, Sachiko Goto","doi":"10.18926/AMO/67196","DOIUrl":"https://doi.org/10.18926/AMO/67196","url":null,"abstract":"We propose a sitting position that achieves both high image quality and a reduced radiation dose in elbow joint imaging by area detector computed tomography (ADCT), and we compared it with the 'superman' and supine positions. The volumetric CT dose index (CTDIvol) for the sitting, superman, and supine positions were 2.7, 8.0, and 20.0 mGy and the dose length products (DLPs) were 43.4, 204.7, and 584.8 mGy • cm, respectively. In the task-based transfer function (TTF), the highest value was obtained for the sitting position in both bone and soft tissue images. The noise power spectrum (NPS) of bone images showed that the superman position had the lowest value up to approx. 1.1 cycles/mm or lower, whereas the sitting position had the lowest value when the NPS was greater than approx. 1.1 cycles/mm. The overall image quality in an observer study resulted in the following median Likert scores for Readers 1 and 2: 5.0 and 5.0 for the sitting position, 4.0 and 3.5 for the superman position, and 4.0 and 2.0 for the supine position. These results indicate that our proposed sitting position with ADCT of the elbow joint can provide superior image quality and allow lower radiation doses compared to the superman and supine positions.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"215-225"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Reduced Skeletal Muscle Mass on Patients with Knee Osteoarthritis. 骨骼肌质量下降对膝关节骨性关节炎患者的影响

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67199

Manabu Akagawa, Hidetomo Saito, Yasuhiro Takahashi, Yosuke Iwamoto, Junpei Iida, Takayuki Yoshikawa, Toshiki Abe, Kimio Saito, Hiroaki Kijima, Yuji Kasukawa, Michio Hongo, Naohisa Miyakoshi

{"title":"The Impact of Reduced Skeletal Muscle Mass on Patients with Knee Osteoarthritis.","authors":"Manabu Akagawa, Hidetomo Saito, Yasuhiro Takahashi, Yosuke Iwamoto, Junpei Iida, Takayuki Yoshikawa, Toshiki Abe, Kimio Saito, Hiroaki Kijima, Yuji Kasukawa, Michio Hongo, Naohisa Miyakoshi","doi":"10.18926/AMO/67199","DOIUrl":"https://doi.org/10.18926/AMO/67199","url":null,"abstract":"Although several studies have suggested a possible association between sarcopenia and knee osteoarthritis (OA) in the elderly, there remains no definitive evidence. Recently, however, the serum creatinine/cystatin C ratio (sarcopenia index: SI) was reported to correlate with skeletal muscle mass. The present retrospective study therefore investigated the impact of reduced skeletal muscle mass on advanced knee OA using SI. In 55 individuals scheduled for knee osteotomy or knee arthroplasty, correlations between SI and patient-reported outcomes such as the Knee Society Score (KSS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Oxford Knee Score (OKS) were explored. Significant associations were found between SI and the KSS functional activity score (β=0.37; p=0.022), KOOS subscale for activities of daily living (β=0.42; p=0.0096), and OKS (β=0.42; p=0.0095). This study underscores the role of reduced muscle mass in functional outcomes and introduces SI as a valuable marker for assessing muscle loss in knee OA patients.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"245-250"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoughts on and Proposal for the Education, Training, and Recruitment of Infectious Disease Specialists. 关于传染病专科医生的教育、培训和招聘的想法和建议。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67195

Hideharu Hagiya

{"title":"Thoughts on and Proposal for the Education, Training, and Recruitment of Infectious Disease Specialists.","authors":"Hideharu Hagiya","doi":"10.18926/AMO/67195","DOIUrl":"10.18926/AMO/67195","url":null,"abstract":"The global pandemic of COVID-19 has underscored the significance of establishing and sustaining a practical and efficient infection control system for the benefit and welfare of society. Infectious disease (ID) specialists are expected to take on leadership roles in enhancing organizational infrastructures for infection prevention and control (IPC) at the hospital, community, and national levels. However, due to an absolute shortage and an uneven distribution, many core hospitals currently lack the ID specialists. Given the escalating global risk of emerging and re-emerging infectious diseases as well as antimicrobial resistance pathogens, the education and training of ID specialists constitutes an imperative concern. As demonstrated by historical changes in the healthcare reimbursement system, the establishment and enhancement of IPC measures is pivotal to ensuring medical safety. The existing structure of academic society-driven certification and training initiatives for ID specialists, contingent upon the discretionary decisions of individual physicians, possesses both quantitative and qualitative shortcomings. In this article, I first address the present situations and challenges related to ID specialists and then introduce my idea of securing ID specialists based on the new concepts and platforms; (i) ID Specialists as National Credentials, (ii) Establishment of the Department of Infectious Diseases in Medical and Graduate Schools, (iii) Endowed ID Educative Courses Funded by Local Government and Pharmaceutical Companies, and (iv) Recruitment of Young Physicians Engaged in Healthcare Services in Remote Areas. As clarified by the COVID-19 pandemic, ID specialists play a crucial role in safeguarding public health. Hopefully, this article will advance the discussion and organizational reform for the education and training of ID specialists.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"205-213"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Efficacy and Safety of Tenofovir Disoproxil Fumarate in Intercepting Mother-to-Child Transmission of Hepatitis B Virus. 评估富马酸替诺福韦酯阻断乙型肝炎病毒母婴传播的有效性和安全性。

IF 0.5 4区医学

Acta medica Okayama Pub Date : 2024-04-01 DOI: 10.18926/AMO/66913

Dongxiang Han, Jianxiu Du, Wei Wang, Cui Wang

{"title":"Evaluation of the Efficacy and Safety of Tenofovir Disoproxil Fumarate in Intercepting Mother-to-Child Transmission of Hepatitis B Virus.","authors":"Dongxiang Han, Jianxiu Du, Wei Wang, Cui Wang","doi":"10.18926/AMO/66913","DOIUrl":"10.18926/AMO/66913","url":null,"abstract":"Vertical transmission of hepatitis B virus (HBV), especially in Asia, is a key target in the global elimination of HBV. This study assessed the effects of tenofovir disoproxil fumarate (TDF) in pregnant women for mother-to-infant transmission of HBV. A total of 122 pregnant women at our hospital met the inclusion criteria for high HBV DNA viral loads. They were randomly divided into TDF-treatment (n=70) and placebo (n=52) groups. Maternal liver function and serum HBV DNA load were tested before and after treatment. Clinical and laboratory data of infants were assayed at delivery and 7-months post-partum visit and compared between the two groups. There was no difference in clinical characteristics of participants between the two groups. There were no significant differences in liver function markers, including alanine aminotransferase, total bilirubin, blood creatinine, and blood urea nitrogen levels before and after TDF treatment. The serum HBV DNA viral load of the TDF-treated group became significantly lower than those of the control group and their own pre-medication levels. Infants showed no significant difference in body growth, including weight, height, head size, and five-min Apgar score. At 7 months after birth, 94.29% of infants in the TDF group and 86.54% of control-group infants had protective HBsAb levels ≥ 10 mIU/ml (p>0.05). The HBV infection rate of infants in the TDF-treated group was lower than that in the non-treated group. In high-HBV-DNA-load pregnant women, TDF administered from 28 weeks gestational age to delivery was associated with a lower risk of mother-to-infant transmission of HBV.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 2","pages":"107-113"},"PeriodicalIF":0.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140846699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Roles of Neuropeptide Y in Respiratory Disease Pathogenesis via the Airway Immune Response. 神经肽 Y 通过气道免疫反应在呼吸道疾病发病机制中的作用

IF 0.5 4区医学

Acta medica Okayama Pub Date : 2024-04-01 DOI: 10.18926/AMO/66912

Junko Itano, Katsuyuki Kiura, Yoshinobu Maeda, Nobuaki Miyahara

引用次数: 0

Impacts of Age and Gender on Brain Edema in a Mouse Water Intoxication Model. 小鼠水中毒模型中年龄和性别对脑水肿的影响

IF 0.5 4区医学

Acta medica Okayama Pub Date : 2024-04-01 DOI: 10.18926/AMO/66914

Emi Nakamura-Maruyama, Keiichiro Irie, Kazuhiko Narita, Naoyuki Himi, Osamu Miyamoto, Takehiro Nakamura

{"title":"Impacts of Age and Gender on Brain Edema in a Mouse Water Intoxication Model.","authors":"Emi Nakamura-Maruyama, Keiichiro Irie, Kazuhiko Narita, Naoyuki Himi, Osamu Miyamoto, Takehiro Nakamura","doi":"10.18926/AMO/66914","DOIUrl":"https://doi.org/10.18926/AMO/66914","url":null,"abstract":"Brain edema causes abnormal fluid retention and can be fatal in severe cases. Although it develops in various diseases, most treatments for brain edema are classical. We analyzed the impacts of age and gender on the characteristics of a water intoxication model that induces pure brain edema in mice and examined the model's usefulness for research regarding new treatments for brain edema. C57BL/6J mice received an intraperitoneal administration of 10% body weight distilled water, and we calculated the brain water content by measuring the brain-tissue weight immediately after dissection and after drying. We analyzed 8-OHdG and caspase-3 values to investigate the brain damage. We also applied this model in aquaporin 4 knockout (AQP4-) mice and compared these mice with wild-type mice. The changes in water content differed by age and gender, and the 8-OHdG and caspase-3 values differed by age. Suppression of brain edema by AQP4- was also confirmed. These results clarified the differences in the onset of brain edema by age and gender, highlighting the importance of considering the age and gender of model animals. Similar studies using genetically modified mice are also possible. Our findings indicate that this water intoxication model is effective for explorations of new brain edema treatments.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 2","pages":"115-122"},"PeriodicalIF":0.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0