Acta medica Okayama最新文献_第3页

Emotional Changes among Young Patients with Breast Cancer to Foster Relationship-Building with Their Partners: A Qualitative Study. 年轻乳腺癌患者的情绪变化促进其与伴侣的关系：一项定性研究。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-06-01 DOI: 10.18926/AMO/68726

Ayumi Yoshikawa, Naruto Taira, Mayumi Okanaga, Shinya Saito

{"title":"Emotional Changes among Young Patients with Breast Cancer to Foster Relationship-Building with Their Partners: A Qualitative Study.","authors":"Ayumi Yoshikawa, Naruto Taira, Mayumi Okanaga, Shinya Saito","doi":"10.18926/AMO/68726","DOIUrl":"https://doi.org/10.18926/AMO/68726","url":null,"abstract":"We investigated the emotional changes that young patients with breast cancer need to undergo in order to foster relationship-building with their partners by conducting a qualitative descriptive study (March 1 to Nov. 26, 2021) and semi-structured interviews with eight postoperative patients (age 20-40 years) with breast cancer. The data were analyzed using the modified grounded theory approach (M-GTA), yielding five categories: (i) Awareness of being a breast cancer patient, (ii) Being at a loss, (iii) Support from significant others, (iv) The struggle to transition from being a patient with cancer to becoming \"the person I want to be\", and (v) Reaching the \"me\" I want to be who can face building a relationship with a partner. These findings suggest that young breast cancer patients must feel that they can lead a normal life through activities such as work or acquiring qualifications before building relationships with their partners, and that getting closer to their desired selves is important. Nurses can provide information to young patients with breast cancer to assist them in building a solid relationship with their partners. We believe that this support may enhance the patients' quality of life and help them achieve stronger relationships with their partners.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 3","pages":"185-195"},"PeriodicalIF":0.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rheumatoid Arthritis with Rapid Destructive Arthropathy of the Shoulder due to Calcium Pyrophosphate Deposition. 焦磷酸钙沉积引起的类风湿性关节炎伴快速破坏性肩关节病变。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-06-01 DOI: 10.18926/AMO/68727

Naoki Kondo, Rika Kakutani, Tomoharu Mochizuki, Junichi Wakui, Nariaki Hao, Eiji Kinoshita, Hiroyuki Kawashima

引用次数: 0

Promising Effectiveness of Combined Chemotherapy and Immunotherapy in Patients with Advanced Non-small Cell Lung Cancer: A Real-World Prospective Observational Study (CS-Lung-003). 化疗和免疫治疗联合治疗晚期非小细胞肺癌的疗效：一项现实世界前瞻性观察研究（CS-Lung-003）。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-06-01 DOI: 10.18926/AMO/68724

Nobuhiro Kanaji, Kazuya Nishii, Yukari Tsubata, Mika Nakao, Takae Okuno, Sachi Okawa, Kenji Takata, Masahiro Kodani, Masahiro Yamasaki, Kazunori Fujitaka, Tetsuya Kubota, Masaaki Inoue, Naoki Watanabe, Katsuyuki Hotta

{"title":"Promising Effectiveness of Combined Chemotherapy and Immunotherapy in Patients with Advanced Non-small Cell Lung Cancer: A Real-World Prospective Observational Study (CS-Lung-003).","authors":"Nobuhiro Kanaji, Kazuya Nishii, Yukari Tsubata, Mika Nakao, Takae Okuno, Sachi Okawa, Kenji Takata, Masahiro Kodani, Masahiro Yamasaki, Kazunori Fujitaka, Tetsuya Kubota, Masaaki Inoue, Naoki Watanabe, Katsuyuki Hotta","doi":"10.18926/AMO/68724","DOIUrl":"10.18926/AMO/68724","url":null,"abstract":"This prospective observational study investigated the clinical status of patients with advanced non-small cell lung cancer (NSCLC) treated with cytotoxic chemotherapy+an immune checkpoint inhibitor (chemo + IO) as first-line treatment in a real-world setting. The cases of 98 patients treated with chemo + IO were prospectively collected and analyzed for effectiveness and safety. The response rate to chemo + IO was 46.9%, and the disease control rate was 76.5%. The median progression-free survival and overall survival (OS) in the total population were 5.2 and 22.3 months, respectively. The patients positive for PD-L1 (≥ 1%) showed significantly longer OS than the negative group (<1%) (median 26.7 vs. 18.7 months, p=0.04). Pre-existing interstitial lung disease (ILD) was associated with shorter OS than the absence of ILD (median 9.0 vs. 22.6 months, p<0.01). Immunerelated adverse events (irAEs) were observed in 28 patients (28.6%). The most frequent irAE was ILD (n=11); Grade 1 (n=1 patient), G2 (n=5), G3 (n=4), and only a single patient with a G5 irAE. In this CS-Lung-003 study, first-line chemo + IO in a real-world setting showed good effectiveness, comparable to that observed in international clinical trials. In real-world practice, chemo + IO is a promising and steadfast strategy.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 3","pages":"167-176"},"PeriodicalIF":0.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Postoperative Irradiation in Patients with cN0 Early Breast Cancer Treated with Sentinel Lymph Node Surgery. 前哨淋巴结手术治疗cN0早期乳腺癌患者的术后放疗效果。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68648

Hiroshi Isozaki, Sasau Matsumoto, Takehiro Takama, Yuka Isozaki

{"title":"Effectiveness of Postoperative Irradiation in Patients with cN0 Early Breast Cancer Treated with Sentinel Lymph Node Surgery.","authors":"Hiroshi Isozaki, Sasau Matsumoto, Takehiro Takama, Yuka Isozaki","doi":"10.18926/AMO/68648","DOIUrl":"https://doi.org/10.18926/AMO/68648","url":null,"abstract":"To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 2","pages":"101-107"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcified Amorphous Tumor of the Left Ventricle with Paroxysmal Atrial Fibrillation. 伴有阵发性心房颤动的左心室钙化无定形肿瘤。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68653

Yasufumi Fujita, Shuji Shimizu, Makoto Mohri

引用次数: 0

A Case of Retinitis Pigmentosa Diagnosed with Severe Anterior Capsule Contraction after Cataract Surgery. 视网膜色素变性白内障术后前囊严重收缩1例。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68652

Akihiro Tsuji, Yusuke Shiode, Shuhei Kimura, Mio Hosokawa, Ryo Matoba, Tetsuro Morita, Kosuke Takahashi, Yuki Morizane

引用次数: 0

For Vol. 79, No.1 pp39-45 Could the Trabecular Bone Score be a Complementary Tool for Evaluating Degenerative Lumbar Vertebrae? 在Vol. 79, No.1 pp39-45骨小梁评分是否可以作为评估退行性腰椎的辅助工具？

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01

引用次数: 0

From a Congenital Defect to Cancer: A Case of Squamous Cell Carcinoma in a Neglected Myelomeningocele. 从先天性缺陷到癌症：一例被忽视的脊髓脊膜膨出伴鳞状细胞癌。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68650

Abhishek Gautam, Rahul Kenawadekar, Virupaxi Hattiholi, Praful Suresh Maste

引用次数: 0

Safe Resection of Esophageal Cancer with a Non-Recurrent Inferior Laryngeal Nerve Associated with an Aberrant Right Subclavian Artery Using Intraoperative Nerve Monitoring. 术中神经监测应用于非复发喉下神经伴异常右锁骨下动脉食管癌的安全切除。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68654

Yasushige Takeda, Kazuhiro Noma, Naoaki Maeda, Yohei Mizusawa, Hijiri Matsumoto, Yuhei Kondo, Tomoyoshi Kunitomo, Yukinori Tanoue, Masashi Hashimoto, Shunsuke Tanabe, Toshiyoshi Fujiwara

引用次数: 0

Potential for Radiation Dose Reduction in Temporal Bone CT Imaging Using Photon-Counting Detector CT. 光子计数检测器CT在颞骨CT成像中降低辐射剂量的潜力。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2025-04-01 DOI: 10.18926/AMO/68645

Fumiyo Higaki, Yusuke Morimitsu, Toshihiro Iguchi, Sung Il Hwang, Takahiro Kitayama, Yuka Takahashi, Mayu Uka, Noriaki Akagi, Akiko Sugaya, Toshiharu Mitsuhashi, Yusuke Matsui, Takao Hiraki

{"title":"Potential for Radiation Dose Reduction in Temporal Bone CT Imaging Using Photon-Counting Detector CT.","authors":"Fumiyo Higaki, Yusuke Morimitsu, Toshihiro Iguchi, Sung Il Hwang, Takahiro Kitayama, Yuka Takahashi, Mayu Uka, Noriaki Akagi, Akiko Sugaya, Toshiharu Mitsuhashi, Yusuke Matsui, Takao Hiraki","doi":"10.18926/AMO/68645","DOIUrl":"https://doi.org/10.18926/AMO/68645","url":null,"abstract":"Temporal bone computed tomography (CT) is frequently performed for pediatric patients with ear diseases. Advances in CT technology have improved diagnostic imaging quality, but reduction of radiation exposure remains a goal. We evaluated the potential for radiation dose reduction in temporal bone CT examinations using porcine ear ossicles and a photon-counting detector CT system. Three scans of the bilateral temporal bone were performed on each of three pig cadaver heads. In each of seven successive imaging sessions, the radiation dose was reduced by an additional one-seventh of the recommended dose (RD). Two board-certified radiologists independently scored the resulting images on a scale of 1 to 5 points, where 5 represented the image quality at the RD. Images scoring ≥4.5 points were considered acceptable. Noise was assessed in a 2-cm-diameter region near the ear ossicles, and standard deviation was measured for each of the seven decrements from the RD. As the radiation dose decreased, the noise progressively increased, and visual assessment scores progressively decreased. Acceptable image scores were obtained at six-sevenths (4.9), five-sevenths (4.8), four-sevenths (4.7), and three-sevenths (4.6) of the RD. Thus, acceptable porcine temporal bone CT images were obtained with a radiation dose reduction of approximately 50%.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"79 2","pages":"75-80"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0