Acta medica Okayama最新文献

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Surgical Treatment of an Abdominal Aortic Aneurysm in a Patient with a Liver Abscess. 肝脓肿患者腹主动脉瘤的手术治疗。
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67553
Gentaro Kato, Yuto Narumiya, Michihiro Okuyama, Shuji Shimizu, Kenji Sangawa, Shu Yamamoto
{"title":"Surgical Treatment of an Abdominal Aortic Aneurysm in a Patient with a Liver Abscess.","authors":"Gentaro Kato, Yuto Narumiya, Michihiro Okuyama, Shuji Shimizu, Kenji Sangawa, Shu Yamamoto","doi":"10.18926/AMO/67553","DOIUrl":"https://doi.org/10.18926/AMO/67553","url":null,"abstract":"<p><p>The presence of an intraperitoneal source of infection, e.g., a liver abscess, can be an obstacle to performing an abdominal aortic surgery with a midline laparotomy because graft infection is one of the most critical complications of aortic surgery. We report the successful Y-grafting of a pararenal abdominal aortic aneurysm through a retroperitoneal approach in a 67-year-old male undergoing liver abscess drainage. The retroperitoneal approach to the abdominal aorta may be useful for abdominal aortic surgery in patients with a localized intraperitoneal infection.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"345-347"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Middle-Ear Salivary Gland Choristoma with Congenital, Single-Sided Hearing Loss. 中耳唾液腺瘤伴先天性单侧听力损失
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67554
Yuichiro Tominaga, Akiko Sugaya, Shin Kariya, Aiko Shimizu, Yuko Kataoka, Mizuo Ando
{"title":"Middle-Ear Salivary Gland Choristoma with Congenital, Single-Sided Hearing Loss.","authors":"Yuichiro Tominaga, Akiko Sugaya, Shin Kariya, Aiko Shimizu, Yuko Kataoka, Mizuo Ando","doi":"10.18926/AMO/67554","DOIUrl":"https://doi.org/10.18926/AMO/67554","url":null,"abstract":"<p><p>Middle-ear salivary gland choristoma (SGCh) is a rare, benign tumor that causes conductive hearing loss owing to middle-ear morphological abnormalities. Early diagnosis is challenging, and surgical resection is indispensable for a definitive diagnosis. We report the case of a 3-year-old boy diagnosed with middle-ear SGCh during the follow-up period for left-sided hearing loss discovered at newborn hearing screening (NHS). Long-term follow-up after the NHS result, subsequent computed tomography/magnetic resonance imaging, and surgical resection led to its relatively early diagnosis and treatment.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"349-355"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multicenter Remote-Access Simulation of Vaginal Delivery for High-Flexibility Medical Education during the Coronavirus Pandemic. 多中心远程访问模拟阴道分娩,在冠状病毒大流行期间开展高灵活性医学教育。
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67547
Eriko Eto, Jota Maki, Noriyuki Yamashita, Toru Hasegawa, Ayano Suemori, Hikari Nakato, Hikaru Oba, Tomohiro Mitoma, Sakurako Mishima, Satoe Kirino, Akiko Ohira, Hisashi Masuyama
{"title":"Multicenter Remote-Access Simulation of Vaginal Delivery for High-Flexibility Medical Education during the Coronavirus Pandemic.","authors":"Eriko Eto, Jota Maki, Noriyuki Yamashita, Toru Hasegawa, Ayano Suemori, Hikari Nakato, Hikaru Oba, Tomohiro Mitoma, Sakurako Mishima, Satoe Kirino, Akiko Ohira, Hisashi Masuyama","doi":"10.18926/AMO/67547","DOIUrl":"https://doi.org/10.18926/AMO/67547","url":null,"abstract":"<p><p>During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku-Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered \"satisfied\" or \"very satisfied\" with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"313-322"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Recipient Age on Perioperative Complications after Pediatric Liver Transplantation: A Single-Center Retrospective Study. 受体年龄对小儿肝移植术后围手术期并发症的影响:单中心回顾性研究
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67548
Akira Katayama, Satoshi Kimura, Takashi Matsusaki, Hiroshi Morimatsu
{"title":"Effect of Recipient Age on Perioperative Complications after Pediatric Liver Transplantation: A Single-Center Retrospective Study.","authors":"Akira Katayama, Satoshi Kimura, Takashi Matsusaki, Hiroshi Morimatsu","doi":"10.18926/AMO/67548","DOIUrl":"https://doi.org/10.18926/AMO/67548","url":null,"abstract":"<p><p>It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"323-330"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Gallbladder Metastasis of Malignant Melanoma. 一例恶性黑色素瘤胆囊转移。
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67205
Hitoshi Minagi, Hideki Aoki, Susumu Doita, Eiki Miyake, Toshihiro Ogawa, Fumitaka Taniguchi, Megumi Watanabe, Takashi Arata, Koh Katsuda, Kohji Tanakaya
{"title":"A Case of Gallbladder Metastasis of Malignant Melanoma.","authors":"Hitoshi Minagi, Hideki Aoki, Susumu Doita, Eiki Miyake, Toshihiro Ogawa, Fumitaka Taniguchi, Megumi Watanabe, Takashi Arata, Koh Katsuda, Kohji Tanakaya","doi":"10.18926/AMO/67205","DOIUrl":"https://doi.org/10.18926/AMO/67205","url":null,"abstract":"<p><p>In the clinical course of malignant melanoma, which can metastasize to multiple organs, gallbladder metastases are rarely detected. A 69-year-old man who underwent resection of a primary malignant melanoma was subsequently treated with nivolumab for lung metastases and achieved complete response. Seven years after surgery, multiple nodules were found in the gallbladder, and he underwent laparoscopic cholecystectomy. The postoperative diagnosis was metastases of malignant melanoma. He has been recurrence-free 8 months after surgery. If radical resection is possible, such surgery should be performed for gallbladder metastases found in patients with other controlled lesions of malignant melanoma.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"291-294"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Lipopolysaccharide on the Duration of Zolpidem-Induced Loss of Righting Reflex in Mice. 脂多糖对唑吡坦诱导小鼠丧失向右转反射持续时间的影响
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67197
Yudai Wada, Soichiro Ushio, Yoshihisa Kitamura, Yoshito Zamami, Toshiaki Sendo
{"title":"Effect of Lipopolysaccharide on the Duration of Zolpidem-Induced Loss of Righting Reflex in Mice.","authors":"Yudai Wada, Soichiro Ushio, Yoshihisa Kitamura, Yoshito Zamami, Toshiaki Sendo","doi":"10.18926/AMO/67197","DOIUrl":"https://doi.org/10.18926/AMO/67197","url":null,"abstract":"<p><p>Zolpidem, a non-benzodiazepine hypnotic, is primarily used to treat insomnia. In a previous study, pior treatment with non-benzodiazepine receptor agonists was associated with inflammation. The present study aimed to clarify the association between the effects of zolpidem and inflammation in mice treated with lipopolysaccharide (LPS), a known model of inflammation. We assessed the zolpidem-induced loss of righting reflex (LORR) duration 24 h after LPS treatment in mice. Additionally, the expressions of γ-aminobutyric acid (GABA)A receptor subunit and K+-Cl- cotransporter isoform 2 (KCC2) mRNA in the hippocampus and frontal cortex were examined in LPS-treated mice. Pretreatment with LPS was associated with significantly prolonged duration of zolpidem-induced LORR compared to control mice. This effect was significantly attenuated by administering bicuculline, a GABAA receptor antagonist, or flumazenil, a benzodiazepine receptor antagonist, in LPS-treated mice. Compared to controls, LPS-treated mice showed no significant change in the expression of GABAA receptor subunits in the hippocampus or frontal cortex. Bumetanide, an Na+-K+-2Cl- cotransporter isoform 1 blocker, attenuated the extended duration of zolpidem-induced LORR observed in LPS-treated mice. LPS significantly decreased Kcc2 mRNA expression in the hippocampus and the frontal cortex. These findings suggest that inflammation increases zolpidem-induced LORR, possibly through a reduction in KCC2 expression.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"227-235"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organized Chronic Subdural Hematoma (OCSDH) Mimicking Meningioma. 模仿脑膜瘤的有组织慢性硬膜下血肿 (OCSDH)。
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67204
Shuichiro Hirano, Yoshihiro Otani, Kentaro Fujii, Isao Date
{"title":"Organized Chronic Subdural Hematoma (OCSDH) Mimicking Meningioma.","authors":"Shuichiro Hirano, Yoshihiro Otani, Kentaro Fujii, Isao Date","doi":"10.18926/AMO/67204","DOIUrl":"https://doi.org/10.18926/AMO/67204","url":null,"abstract":"<p><p>Organized chronic subdural hematoma (OCSDH) is a relatively rare condition that forms over a longer period of time compared to chronic subdural hematoma and is sometimes difficult to diagnose with preoperative imaging. We resected an intracranial lesion in a 37-year-old Japanese man; the lesion had been increasing in size for >17 years. The preoperative diagnosis based on imaging findings was meningioma; however, pathological findings revealed OCSDH. Clinicians should be aware that OCSDH mimics other tumors and consider surgical strategies for this disease.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"285-290"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Multidisciplinary Approach to Hip Fractures: Evaluating Outcomes on Mortality and Secondary Hip Fractures. 多学科方法治疗髋部骨折:评估死亡率和继发性髋部骨折的结果。
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67198
Osamu Muraoka, Norio Imai, Tatsuya Kuraishi, Makoto Imai, Takashi Fukuhara, Toshifumi Yoshimine
{"title":"A Multidisciplinary Approach to Hip Fractures: Evaluating Outcomes on Mortality and Secondary Hip Fractures.","authors":"Osamu Muraoka, Norio Imai, Tatsuya Kuraishi, Makoto Imai, Takashi Fukuhara, Toshifumi Yoshimine","doi":"10.18926/AMO/67198","DOIUrl":"https://doi.org/10.18926/AMO/67198","url":null,"abstract":"<p><p>Fracture liaison services (FLS) have been introduced in Japan and several other countries to reduce medical complications and secondary fractures. We aimed to evaluate the effects of the implementation of an FLS approach on patient outcomes during hospitalization at our hospital and over a 2-year follow-up post-injury. This retrospective cohort study included patients ≥ 60 years admitted to our hospital for hip fragility fractures between October 1, 2016, and July 31, 2020. Patient groups were defined as those treated before (control group, n=238) and after (FLS group, n=196) establishment of the FLS protocol at our institution. The two groups were compared in terms of time to surgery, length of hospital stay, and the incidence of complications after admission, including secondary hip fracture and mortality rates. The follow-up period was 24 months. FLS focuses on early surgery within 48 h of injury and assessing osteoporosis treatment before injury to guide post-discharge anti-osteoporosis medication. FLS reduced the length of hospital stay (p<0.001) and the prevalence of complications after admission (p<0.001), particularly cardiovascular disease, and it increased adherence to anti-osteoporosis medication. These FLS effects resulted in lower secondary hip fracture and mortality rates at 12 and 24 months post-injury. FLS for fragility hip fractures can improve patient outcomes during hospitalization and over a 2-year follow-up period.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"237-243"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Analysis of Thoracic Rotation Exercises: Range of Motion Improvement in Standing and Quadruped Variants. 胸廓旋转运动的比较分析:站立式和四足式运动范围的改善
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67200
Koji Murofushi, Sho Mitomo, Kenji Hirohata, Hidetaka Furuya, Hiroki Katagiri, Koji Kaneoka, Kazuyoshi Yagishita
{"title":"Comparative Analysis of Thoracic Rotation Exercises: Range of Motion Improvement in Standing and Quadruped Variants.","authors":"Koji Murofushi, Sho Mitomo, Kenji Hirohata, Hidetaka Furuya, Hiroki Katagiri, Koji Kaneoka, Kazuyoshi Yagishita","doi":"10.18926/AMO/67200","DOIUrl":"https://doi.org/10.18926/AMO/67200","url":null,"abstract":"<p><p>There have been few investigations into the effectiveness of thoracic spine exercises for improving thoracic range of motion (ROM) in any plane. This study assessed the effectiveness of two thoracic spine exercises: one in the quadruped position and one in the thoracic standing position. We determined how these exercises affect thoracic spine mobility ROM over a 2-week intervention period. Thirty-nine healthy participants were enrolled and assigned to a Quadruped Thoracic Rotation group (n=17 participants: 9 females and 8 males) or Flamenco Thoracic Spine Rotation group (n=22: 14 females and 8 males). All participants were administered a KOJI AWARENESSTM screening test, and the initial thoracic spine ROM before intervention exercise was measured in a laboratory setting. Quadruped Thoracic Rotation was performed as the quadruped exercise and Flamenco Thoracic Spine Rotation as the standing exercise. The KOJI AWARENESSTM thoracic spine test and ROM were evaluated on the day after the first exercise session and again after the program. Despite their different approaches to thoracic mobility, the quadruped exercise and standing exercise achieved equivalent improvement in thoracic ROM after 2 weeks. Practitioners have a range of exercise options for enhancing thoracic mobility based on their environmental or task-specific needs.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"251-258"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of the Lipid Profile and Oxidative Stress in Fatigue, Sleep Disorders and Cognitive Impairment in Patients with Multiple Sclerosis. 血脂谱和氧化应激在多发性硬化症患者疲劳、睡眠障碍和认知障碍中的作用
IF 0.6 4区 医学
Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67201
Gonul Vural, Esra Demir, Sadiye Gumusyayla, Funda Eren, Serdar Barakli, Salim Neselioglu, Ozcan Erel
{"title":"The Role of the Lipid Profile and Oxidative Stress in Fatigue, Sleep Disorders and Cognitive Impairment in Patients with Multiple Sclerosis.","authors":"Gonul Vural, Esra Demir, Sadiye Gumusyayla, Funda Eren, Serdar Barakli, Salim Neselioglu, Ozcan Erel","doi":"10.18926/AMO/67201","DOIUrl":"https://doi.org/10.18926/AMO/67201","url":null,"abstract":"<p><p>The aim of this study is to investigate the relationship of the lipid profile, dysfunctional high-density lipoprotein, ischaemia-modified albumin and thiol-disulfide homeostasis with cognitive impairment, fatigue and sleep disorders in patients with multiple sclerosis. The cognitive functions of patients were evaluated with the Brief International Cognitive Assessment for Multiple Sclerosis battery. Fatigue was evaluated with the Fatigue Severity Scale and the Fatigue Impact Scale. The Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale were used to assess patients' sleep disturbance. Peripheral blood samples were collected, and lipid levels and myeloperoxidase and paraoxonase activity were measured. The myeloperoxidase/paraoxonase ratio, which indicates dysfunctional high-density lipoprotein, was calculated. Thiol-disulfide homeostasis and ischaemia-modified albumin were measured.<br> We did not identify any relationship between dysfunctional high-density lipoprotein and the physical disability, cognitive decline, fatigue and sleep problems of multiple sclerosis. Thiol-disulfide homeostasis was associated with cognitive scores. The shift of the balance towards disulfide was accompanied by a decrease in cognitive scores. On the other hand, we did not detect any relationship between fatigue and sleep disorders and thiol-disulfide homeostasis. Our findings revealed a possible correlation between cognitive dysfunction and thiol-disulfide homeostasis in multiple sclerosis patients.</p>","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"259-270"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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