Acta medica Okayama最新文献_第2页

Occult Nesidioblastosis Detected by 111In-Pentetreotide Single-Photon Emission Computed Tomography. 通过 111In-Pentetreotide 单光子发射计算机断层扫描发现的隐匿性网状母细胞增生症

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67667

Shinya Sakamoto, Motoyasu Tabuchi, Rika Yoshimatsu, Ai Hishida, Manabu Matsumoto, Jun Iwata, Takehiro Okabayashi

{"title":"Occult Nesidioblastosis Detected by 111In-Pentetreotide Single-Photon Emission Computed Tomography.","authors":"Shinya Sakamoto, Motoyasu Tabuchi, Rika Yoshimatsu, Ai Hishida, Manabu Matsumoto, Jun Iwata, Takehiro Okabayashi","doi":"10.18926/AMO/67667","DOIUrl":"https://doi.org/10.18926/AMO/67667","url":null,"abstract":"Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia, is usually observed in children and infants, although more recently adult-onset nesidioblastosis has also been described. We present a case of nesidioblastosis in a 78-year-old man that was detected by 111In-pentetreotide single photon emission computed tomography (SPECT/CT). The patient was transferred to our hospital's emergency department in a hypoglycemic coma. Dynamic enhanced CT could detect no lesion in the pancreas, but an 111In-pentetreotide SPECT/CT scan performed after a similar episode four weeks later showed increased focal uptake at the head of the pancreas. The results of a selective arterial calcium injection test were negative. After careful consideration and discussion among colleagues, surgical intervention was selected, and a pancreaticoduodenectomy was performed. On histology, there were elevated numbers of Langerhans islets in the pancreatic head, and the islets themselves appeared enlarged. Hypertrophic β-cells comprised the majority, but α-cells, δ-cells and pancreatic polypeptide were also detected in the islets. Based on the histopathological results and repeated hyperinsulinemic hypoglycemic crises, the patient was finally diagnosed with adult-onset nesidioblastosis. He had no hypoglycemic symptoms during outpatient follow-up examination. Since 111In-pentetreotide SPECT/CT may be able to detect nesidioblastosis, clinicians should consider this relatively new-modality examination when encountering such cases.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 5","pages":"423-428"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The First Report of Bickerstaff Brainstem Encephalitis Induced by Atezolizumab for Metastatic Breast Cancer. 阿特珠单抗治疗转移性乳腺癌诱发比克斯塔夫脑干脑炎的首次报道

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67665

Kyoko Shimoyama, Atsushi Nakajima, Yoshimitsu Minari

引用次数: 0

Phenotypic and Genetic Characteristics of Carbapenemase-Producing Enterobacterales Isolates at Okayama University Hospital. 冈山大学医院产碳青霉烯酶肠杆菌属分离菌的表型和遗传特征。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67657

Kazuyoshi Gotoh, Makoto Miyoshi, I Putu Bayu Mayura, Shuma Tsuji, Koji Iio, Shinnosuke Fukushima, Osamu Matsushita, Hideharu Hagiya

{"title":"Phenotypic and Genetic Characteristics of Carbapenemase-Producing Enterobacterales Isolates at Okayama University Hospital.","authors":"Kazuyoshi Gotoh, Makoto Miyoshi, I Putu Bayu Mayura, Shuma Tsuji, Koji Iio, Shinnosuke Fukushima, Osamu Matsushita, Hideharu Hagiya","doi":"10.18926/AMO/67657","DOIUrl":"10.18926/AMO/67657","url":null,"abstract":"Spread of carbapenemase-producing Enterobacterales (CPE) is an ongoing public health issue worldwide, including in Japan. In this study, we investigated the phenotypic and genetic characteristics of CPE isolates at Okayama University Hospital over the 5 years (2013-2018) prior to the outbreak of the 2019 coronavirus pandemic. Of 24 carbapenem-resistant Enterobacterales isolated during the study period, we identified 8 CPE isolates harboring blaIMP-1 (5 isolates) and blaIMP-6 genes (3 isolates). Bacterial species and carbapenem susceptibility patterns exhibited diversity. Minimum inhibitory concentrations (MICs) of meropenem were generally higher than those of imipenem and biapenem. Results of pulsed-field gel electrophoresis demonstrated that neither clonal nor plasmid-mediated outbreaks of blaIMP-harboring CPE isolates have developed at our hospital. One Klebsiella oxytoca isolate showed a high MIC (128 μg/mL) of meropenem, which could be explained by the high plasmid copy number. Subsequent analysis of this isolate may elucidate the intricacies of carbapenem resistance profiles among CPE isolates. Collectively, our findings underscore the necessity for ongoing genetic surveillance of CPE, complemented by tailored approaches for infection prevention and control.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 5","pages":"371-376"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Focal Cerebral Hypoperfusion Detected by Arterial Spin-Labeled Magnetic Resonance Imaging in Patients with Migraine Presenting with Neurological Symptoms Concomitant with or without Headache. 通过动脉自旋标记磁共振成像检测伴有或不伴有头痛的偏头痛患者的神经症状的局部脑灌注不足。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67666

Kenichi Kashihara, Minoru Irisawa, Wataru Takao

引用次数: 0

Pediatric Severe Febrile Thrombocytopenia Syndrome: A Case Report and Literature Review. 小儿严重发热性血小板减少综合征：病例报告和文献综述。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67664

Yusuke Toyota, Kazuhiro Uda, Komei Shirabe, Tadashi Moriwake

引用次数: 0

Factors Affecting Dynamic Postural Control Ability in Adolescent Idiopathic Scoliosis. 影响青少年特发性脊柱侧凸动态姿势控制能力的因素。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67655

Ryoko Yamawaki, Yoshiaki Oda, Shuhei Yamane, Koji Uotani, Haruo Misawa, Yoshimi Katayama, Masanori Hamada, Toshifumi Ozaki

引用次数: 0

Small-for-Gestational-Age Status and the Risk of Kawasaki Disease: A Nationwide Birth Cohort in Japan. 小于胎龄状态与川崎病风险：日本全国出生队列。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67656

Satoe Takanaga, Naomi Matsumoto, Tomoka Kadowaki, Soshi Takao, Takashi Yorifuji

{"title":"Small-for-Gestational-Age Status and the Risk of Kawasaki Disease: A Nationwide Birth Cohort in Japan.","authors":"Satoe Takanaga, Naomi Matsumoto, Tomoka Kadowaki, Soshi Takao, Takashi Yorifuji","doi":"10.18926/AMO/67656","DOIUrl":"https://doi.org/10.18926/AMO/67656","url":null,"abstract":"Kawasaki disease (KD) is a pediatric disease of unknown etiology that commonly affects infants in East Asia. Infants born small for gestational age (SGA) have weaker immune systems and are more susceptible to infection. Using data from a nationwide Japanese birth cohort study conducted in 2010 (n=34,579), we investigated whether SGA increases the risk of KD. SGA was defined as birth weight below the 10th percentile for gestational age. The outcome was hospitalization for KD between 6 and 30 months of age. The association between SGA and hospitalization for KD, adjusted for child and maternal factors, was examined using logistic regression. Of the 231 children hospitalized for KD, 9.5% were SGA. Further statistical analysis showed that SGA did not increase the odds ratio (OR) of hospitalization for KD (adjusted OR 1.12, 95% confidence interval 0.71-1.75). This result was not changed with stratification by early daycare attendance and preterm status. Reasons for the lack of association may include the multifactorial pathogenesis of KD; in addition, the types of infections to which SGA infants are predisposed may differ from those triggering KD. Overall, our large nationwide study found no association between SGA and KD.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 5","pages":"363-370"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can Pelvic Lymph Node Dissection in Prostate Cancer Patients with a 5% Briganti Nomogram Cut-off Value Provide an Oncological Benefit? A Large Multi-Institutional Cohort Study in Japan. 5% Briganti Nomogram 临界值的前列腺癌患者盆腔淋巴结清扫能带来肿瘤学获益吗？日本一项大型多机构队列研究。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67546

Naoya Sugihara, Katsuyoshi Hashine, Natsumi Yamashita, Miki Sakamoto, Masato Terashita, Keisuke Funaki, Kaori Saiki, Takatora Sawada, Toshio Kakuda, Kenichi Nishimura, Tetsuya Fukumoto, Noriyosi Miura, Yuki Miyauchi, Tadahiko Kikugawa, Takashi Saika

{"title":"Can Pelvic Lymph Node Dissection in Prostate Cancer Patients with a 5% Briganti Nomogram Cut-off Value Provide an Oncological Benefit? A Large Multi-Institutional Cohort Study in Japan.","authors":"Naoya Sugihara, Katsuyoshi Hashine, Natsumi Yamashita, Miki Sakamoto, Masato Terashita, Keisuke Funaki, Kaori Saiki, Takatora Sawada, Toshio Kakuda, Kenichi Nishimura, Tetsuya Fukumoto, Noriyosi Miura, Yuki Miyauchi, Tadahiko Kikugawa, Takashi Saika","doi":"10.18926/AMO/67546","DOIUrl":"https://doi.org/10.18926/AMO/67546","url":null,"abstract":"The Briganti nomogram (cut-off value 5%) is commonly used to determine the indications for pelvic lymph node dissection (PLND) in patients with prostate cancer. We retrospectively analyzed the potential oncological benefit of PLND based on the 5% cut-off value on the Briganti nomogram. We obtained the data from the Medical Investigation Cancer Network (MICAN) Study, which included 3,463 patients who underwent a radical prostatectomy (RP) at nine institutions in Japan between 2010 and 2020. We included patients with Briganti scores ≥ 5% and a follow-up period ≥6 months and excluded patients categorized in the very high-risk group (based on NCCN categories); a final total of the cases of 1,068 patients were analyzed. The biochemical recurrence (BCR)-free survival was significantly worse in the patients who underwent PLND compared to those who did not (p=0.019). A multivariate analysis showed that high prostate-specific antigen (PSA) levels (p<0.001) and an advanced T-stage (p=0.018) were significant prognostic factors for BCR, whereas PLND had no effect on BCR (p=0.059). Thus, PLND in patients with prostate cancer whose Briganti score was 5% did not provide any oncological benefit. Further research is necessary to determine the indication criteria for conducting PLND.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"307-312"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Subglottic Pleomorphic Adenoma: Magnetic Resonance Findings. 罕见的声门下多形性腺瘤：磁共振检查结果

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67549

Chieko Furukawa, Tomoyasu Tachibana, Tetsuji Nobuhisa, Yuichiro Kanie, Yoji Wani, Jun-Ya Matsumoto, Akifumi Kariya, Asuka Sato, Iichiro Ishikawa, Yuto Naoi, Mizuo Ando

引用次数: 0

Pneumocephalus with Inverted Papilloma in the Frontoethmoidal Sinus: Case Report and Literature Review. 前牙状窦倒置乳头状瘤引发的气胸：病例报告和文献综述。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67550

Seiichiro Makihara, Yoshihiro Otani, Kensuke Uraguchi, Sawako Ono, Aiko Shimizu, Ryosuke Ikemachi, Yosuke Okazaki, Tomoyuki Ota, Hiroshi Matsumoto, Shotaro Miyamoto, Munechika Tsumura, Seiya Hayashi, Michiari Umakoshi, Koji Hirashita, Mizuo Ando

引用次数: 0