Acta medica Okayama最新文献

Partial versus Radical Nephrectomy for Small Renal Cancer: Comparative Propensity Score-Matching Analysis of Cardiovascular Event Risk.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67868

Risa Kubota, Kensuke Bekku, Satoshi Katayama, Takehiro Iwata, Shingo Nishimura, Kohei Edamura, Tomoko Kobayashi, Yasuyuki Kobayashi, Motoo Araki

{"title":"Partial versus Radical Nephrectomy for Small Renal Cancer: Comparative Propensity Score-Matching Analysis of Cardiovascular Event Risk.","authors":"Risa Kubota, Kensuke Bekku, Satoshi Katayama, Takehiro Iwata, Shingo Nishimura, Kohei Edamura, Tomoko Kobayashi, Yasuyuki Kobayashi, Motoo Araki","doi":"10.18926/AMO/67868","DOIUrl":"https://doi.org/10.18926/AMO/67868","url":null,"abstract":"Although partial nephrectomy (PN) is preferred over radical nephrectomy (RN) for preserving renal function in patients with cT1 renal cancer, its impact on cardiovascular events (CVe) remains controversial. This study aimed to compare PN and RN in regard to the occurrence of CVe, including cerebrovascular events and exacerbation of hypertension (HT). We retrospectively analyzed 418 consecutive patients who underwent PN or RN for cT1 renal cancer. Propensity score-matching analysis was used to adjust for imbalances between patients who underwent PN and RN, leaving 102 patients in each group. The 5-year probability of cumulative CVe incidence was 6% in the PN group and 12% in the RN group (p=0.03), with a median follow-up of 73.5 months. The statistical significance was retained after propensity score matching for patients without preoperative proteinuria (p=0.03). For all CVe including cerebrovascular events and exacerbation of HT analyzed, PN provided a lower probability of occurrence than RN in patients with small renal cancers.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 6","pages":"429-437"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Factors for Gangrenous Cholecystitis and the Outcomes of Early Cholecystectomy: A Retrospective Study of a Single-Center City General Hospital.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67869

Mampei Yamashita, Takayuki Tanaka, Yorihisa Sumida, Shoto Yamazaki, Yuki Hara, Akiko Fukuda, Makoto Hisanaga, Koki Wakata, Masato Araki, Susumu Eguchi

{"title":"Risk Factors for Gangrenous Cholecystitis and the Outcomes of Early Cholecystectomy: A Retrospective Study of a Single-Center City General Hospital.","authors":"Mampei Yamashita, Takayuki Tanaka, Yorihisa Sumida, Shoto Yamazaki, Yuki Hara, Akiko Fukuda, Makoto Hisanaga, Koki Wakata, Masato Araki, Susumu Eguchi","doi":"10.18926/AMO/67869","DOIUrl":"https://doi.org/10.18926/AMO/67869","url":null,"abstract":"Gangrenous cholecystitis (GC) is classified as moderate acute cholecystitis according to the Tokyo Guidelines from 2018 (TG18). We evaluated the risk factors for GC and the outcomes of early cholecystectomy. A total of 136 patients who underwent emergency cholecystectomy for acute cholecystitis were retrospectively analyzed; 58 of these patients (42.6%) were diagnosed with GC (GC group) based on our retrospective pathologic diagnosis. We comparatively evaluated the patient backgrounds and surgical outcomes between the GC group and non-GC group. The GC group was significantly older and included more hypertensive patients than the non-GC group. The GC group was prescribed more antibiotics as initial treatment than the non-GC group, and they had more days between onset and surgery. The preoperative white blood cell count and C-reactive protein values were significantly higher in the GC group than in the non-GC group, and these values were predictive factors for GC. Cholecystectomy required a longer operation time and caused greater blood loss in the GC group. The GC group also had longer hospitalization times than the non-GC group; however, no significant differences were observed in terms of postoperative complications. In conclusion, gangrenous changes should be assessed when diagnosing cholecystitis, and appropriate treatment, such as surgery or drainage, should be undertaken.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 6","pages":"439-447"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

C-arm Free Unilateral Biportal Endoscopic Discectomy: A Technical Note.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67878

Hongfei Xiang, Kajetan Latka, Praful Maste, Masato Tanaka, Chetan Kumawat, Shinya Arataki, Yoshihiro Fujiwara, Takuya Taoka, Akiyoshi Miyamoto

{"title":"C-arm Free Unilateral Biportal Endoscopic Discectomy: A Technical Note.","authors":"Hongfei Xiang, Kajetan Latka, Praful Maste, Masato Tanaka, Chetan Kumawat, Shinya Arataki, Yoshihiro Fujiwara, Takuya Taoka, Akiyoshi Miyamoto","doi":"10.18926/AMO/67878","DOIUrl":"https://doi.org/10.18926/AMO/67878","url":null,"abstract":"This report presents a new unilateral biportal endoscopic (UBE) technique for lumbar disc herniation without C-arm guidance. Lumbar disc herniation requires surgical intervention when conservative methods fail. Shifts towards minimally invasive percutaneous endoscopic lumbar discectomy, including uniportal and biportal approaches, have been hindered by challenges such as steep learning curves and reliance on radiation-intensive C-arm guidance. We here describe the use of standard intraoperative navigation in UBE to reduce radiation exposure and increase surgical accuracy. A 24-year-old man with low back and bilateral leg pain with gait disturbance was referred to our hospital. He had had conservative treatment for 12 months in another hospital before admission, but this proved unsuccessful. On admission he had low back pain (VAS 4/10) and bilateral leg pain (VAS 8/10), muscle weakness of the bilateral legs (manual muscle testing (MMT) grade of the extensor hallucis longus: 4/4), and numbness of the bilateral lower legs. Preoperative lumbar MRI showed L4/5 large central disc herniation. He underwent C-arm free UBE discectomy under the guidance of O-arm navigation. The surgery was successful, with postoperative lumbar MRI showing good decompression of the dural sac and bilateral L5 nerve roots. The MMT grade and sensory function of both legs had recovered fully on final follow-up at one year. The new UBE technique under navigation guidance was shown to be useful for lumbar disc herniation. This innovative technique was safe and accurate for the treatment of lumbar intervertebral disc herniation, and minimized radiation exposure to surgeons.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 6","pages":"475-483"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traumatic Neuroma Arising from Surgical Trauma during Conversion from Laparoscopic to Open Cholecystectomy.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67872

Shinya Sakamoto, Motoyasu Tabuchi, Rika Yoshimatsu, Manabu Matsumoto, Jun Iwata, Takehiro Okabayashi

引用次数: 0

Case of Radiation-Induced Angiosarcoma after Breast-Conserving Surgery with Hypofractionated Radiotherapy in a Japanese Patient.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67871

Yujiro Kawata, Kenta Watanabe, Ryoji Tokiya, Takeshi Matsuno, Ryo Tanaka, Naruto Taira, Kuniaki Katsui

引用次数: 0

Secondary Polymyalgia Rheumatica Following SARS-CoV-2 Infection.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67873

Kazuki Ocho, Hideharu Hagiya, Hisashi Ishikawa, Fumio Otsuka

引用次数: 0

Closure of Ventricular Septal Rupture through a Left Thoracotomy in a Patient with a History of Esophageal Reconstruction.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67870

Gentaro Kato, Tatsuya Ogawa, Tomohiro Hayashida, Shuji Shimizu, Shu Yamamoto, Takeshi Shichijo

引用次数: 0

Treatment of Tenosynovial Giant Cell Tumor of the Cervical Spine with Postoperative Anti-RANKL Antibody (Denosumab) Administration.

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-12-01 DOI: 10.18926/AMO/67877

Yuichi Hirata, Takayuki Nagase, Susumu Sasada, Yoshiyuki Ayada, Hayato Miyake, Chiaki Sugahara, Hidetaka Yamamoto, Yoshinao Oda, Takao Yasuhara, Shota Tanaka

引用次数: 0

Prognostic Efficacy of the Albumin Grade in Patients with Hepatocellular Carcinoma. 肝细胞癌患者白蛋白分级的预后效果

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67662

Yuichi Hirano, Kazuhiro Nouso, Kazuya Kariyama, Atsushi Hiraoka, Shohei Shiota, Akiko Wakuta, Satoshi Yasuda, Hidenori Toyoda, Kunihiko Tsuji, Takeshi Hatanaka, Satoru Kakizaki, Atsushi Naganuma, Toshifumi Tada, Ei Itobayashi, Toru Ishikawa, Noritomo Shimada, Koichi Takaguchi, Akemi Tsutsui, Takuya Nagano, Michitaka Imai, Shinichiro Nakamura, Takashi Kumada

{"title":"Prognostic Efficacy of the Albumin Grade in Patients with Hepatocellular Carcinoma.","authors":"Yuichi Hirano, Kazuhiro Nouso, Kazuya Kariyama, Atsushi Hiraoka, Shohei Shiota, Akiko Wakuta, Satoshi Yasuda, Hidenori Toyoda, Kunihiko Tsuji, Takeshi Hatanaka, Satoru Kakizaki, Atsushi Naganuma, Toshifumi Tada, Ei Itobayashi, Toru Ishikawa, Noritomo Shimada, Koichi Takaguchi, Akemi Tsutsui, Takuya Nagano, Michitaka Imai, Shinichiro Nakamura, Takashi Kumada","doi":"10.18926/AMO/67662","DOIUrl":"10.18926/AMO/67662","url":null,"abstract":"We previously found that \"albumin grade\", formerly called the \"ALBS grade,\" demonstrated significant capability for prognostic stratification in hepatocellular carcinoma (HCC) patients treated with lenvatinib. The purpose of the present study was to compare the performance of the albumin grade with that of the modified albumin-bilirubin (mALBI) grade in predicting overall survival of HCC patients with different BCLC stages and treatment types. We enrolled 7,645 Japanese patients newly diagnosed with HCC using the Akaike information criteria (AIC), likelihood ratio, and C-index in different Barcelona Clinic Liver Cancer (BCLC) stages and treatments. The albumin grade showed similar and slightly better performance than the mALBI grade for BCLC stage 0 and A and especially for patients who underwent curative surgery and ablation. In patients treated with transcatheter arterial chemoembolization, molecular targeted agents, and the best supportive care, the mALBI grade had better performance than the albumin grade. However, the differences of the indices were very small in all scenarios. Overall, the albumin grade was comparable in efficacy to the mALBI grade, showing particular benefit for patients with early-stage HCC.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 5","pages":"377-386"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Radon Inhalation on Murine Brain Proteins: Investigation Using Proteomic and Multivariate Analyses. 吸入氡对小鼠脑蛋白质的影响：利用蛋白质组学和多元分析进行研究

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-10-01 DOI: 10.18926/AMO/67663

Shota Naoe, Ayumi Tanaka, Norie Kanzaki, Reiju Takenaka, Akihiro Sakoda, Takaaki Miyaji, Kiyonori Yamaoka, Takahiro Kataoka

{"title":"Effect of Radon Inhalation on Murine Brain Proteins: Investigation Using Proteomic and Multivariate Analyses.","authors":"Shota Naoe, Ayumi Tanaka, Norie Kanzaki, Reiju Takenaka, Akihiro Sakoda, Takaaki Miyaji, Kiyonori Yamaoka, Takahiro Kataoka","doi":"10.18926/AMO/67663","DOIUrl":"10.18926/AMO/67663","url":null,"abstract":"Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 5","pages":"387-399"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0