Acta Medica Philippina最新文献

{"title":"A Systematic Review of Epidemiologic Studies on Scabies in the Philippines.","authors":"Rowena F Genuino, Emilio Q Villanueva, Maria Christina Filomena R Batac, Maria Emilia Ruth V Eusebio, Ysabel Regina H Ortiz, Vincent Ryan C Ang, Miguel Q Ordonez, Hannah May R Ona, Maria Stephanie Fay S Cagayan","doi":"10.47895/amp.vi0.8719","DOIUrl":"10.47895/amp.vi0.8719","url":null,"abstract":"<p><strong>Background and objective: </strong>Scabies is the second most common cause of disability due to skin disease in the Philippines. However, there were no cited studies in Global Burden of Disease 2019 and the disability-adjusted life years (DALY) computations were most likely based on statistical modelling. The Philippine Department of Health has embarked on a program to estimate the disease burden of priority diseases in the country, which include scabies. The last nationwide prevalence survey was 23 years ago. This systematic review aimed to estimate the prevalence or incidence of scabies in the Philippines.</p><p><strong>Methods: </strong>We searched PubMed, Scopus, Herdin, and Philippine Health Research Registry (search date October 2022) for studies on prevalence/incidence (including systematic reviews, cross-sectional studies, cohort studies, case series, registry or census studies) of patients diagnosed with scabies in the Philippines. We excluded narrative reviews, commentaries, and conference proceedings or abstracts. Two reviewers independently screened titles and abstracts, assessed full text reports for eligibility, appraised the quality of included studies, and collected data using a pretested data extraction form. We did not pool studies due to clinical heterogeneity but plotted the individual studies in a forest plot with prevalence estimates and confidence intervals. We reported the median and interquartile range for entire group or relevant subgroups (age, setting) of studies. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess the certainty of evidence.</p><p><strong>Results: </strong>We included nine studies (N=79,065). Most were clinic-based prevalence studies, retrospective chart reviews, conducted in dermatology outpatient clinics, Metro Manila area, and on pediatric populations. Prevalence of scabies was moderate (i.e., between 2 and 10%), ranging from 2.75% (national prevalence survey) to 6.8% (community-based review), to high (> 10%) among pediatric patients in clinic-based retrospective chart reviews (29 to 36%) and institution-based surveys (39.0% to 45%), and a tertiary government university training hospital dermatology clinic (22.9%). The most affected age group was from 0 to 14 y/o, while males tended to have a higher prevalence than females. The cooler month of January had higher prevalence than the hotter month of June in one study.</p><p><strong>Conclusion: </strong>Scabies is common in the Philippines, especially among children and elderly in institutional settings, and during the month of January. There is a need to do a national prevalence survey to identify high-risk areas and to monitor the prevalence of scabies, especially in crowded settings and vulnerable populations. This information can be used for estimating the burden of disease for scabies and guide appropriate health resource allocation.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 22","pages":"92-105"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Mortality among End-Stage Renal Disease Patients with COVID-19 Admitted in a Philippine Tertiary Government Hospital: A Retrospective Cohort Study.","authors":"Saul B Suaybaguio, Jade D Jamias, Marla Vina A Briones","doi":"10.47895/amp.vi0.8374","DOIUrl":"https://doi.org/10.47895/amp.vi0.8374","url":null,"abstract":"<p><strong>Background and objective: </strong>Several studies have examined the predictors of mortality among COVID-19-infected patients; however, to date, few published studies focused on end-stage renal disease patients. The present study, therefore, aims to determine the predictors of in-hospital mortality among end-stage renal disease patients with COVID-19 admitted to a Philippine tertiary hospital.</p><p><strong>Methods: </strong>The researcher utilized a retrospective cohort design. A total of 449 adult end-stage renal disease patients on renal replacement therapy diagnosed with moderate-to-severe COVID-19 and were admitted at the National Kidney and Transplant Institute from June 2020 to 2021 were included. Logistic regression analysis was used to determine the factors associated with in-hospital mortality.</p><p><strong>Results: </strong>In-hospital mortality among end-stage renal disease patients with COVID-19 was 31.18% (95% CI: 26.92-35.69%). Older age (OR=1.03), male sex (OR=0.56), diabetes mellitus (OR=1.80), coronary artery disease (OR=1.71), encephalopathy (OR=7.58), and intubation (OR=30.78) were associated with in-hospital mortality.</p><p><strong>Conclusion: </strong>Patients with ESRD and COVID-19 showed a high in-hospital mortality rate. Older age, diabetes mellitus, coronary artery disease, encephalopathy, and intubation increased the odds of mortality. Meanwhile, males had lower odds of mortality than females.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 22","pages":"44-51"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparison of <i>Lactobacillus acidophilus</i> Adhesion to Metal and Ceramic Brackets with Coated and Uncoated Nickel Titanium Orthodontic Archwires: An In Vitro Study.","authors":"Ardiansyah S Pawinru, Nasyrah Hidayati, Eka Erwansyah, Eddy Heriyanto Habar, Baharuddin M Ranggang, Suhesti Suronoto","doi":"10.47895/amp.vi0.7945","DOIUrl":"https://doi.org/10.47895/amp.vi0.7945","url":null,"abstract":"<p><strong>Background and objective: </strong>According to microbiological investigations, microorganisms, especially Lactobacillus strains, considerably increase after using fixed orthodontic appliances. One of the Lactobacilli bacteria found in the oral cavity is <i>Lactobacillus acidophilus</i>. The purpose of this study was to compare the adhesion of <i>Lactobacillus acidophilus</i> to metal and ceramic brackets with coated and uncoated nickel titanium (NiTi) orthodontic archwires.</p><p><strong>Methods: </strong>Forty () samples were divided into four groups for this in vitro study: 10 metal brackets with coated NiTi archwire, 10 metal brackets with uncoated NiTi archwire, 10 ceramic brackets with coated NiTi archwire, and 10 ceramic brackets with uncoated NiTi archwire. Elisa Reader was used to count the number of <i>Lactobacillus acidophilus</i> attachments, and the one-way ANOVA and Tukey HSD tests were used to analyze all results.</p><p><strong>Results: </strong>The results showed significant differences in the attachment of <i>Lactobacillus Acidophilus</i> between the ceramic bracket and coated NiTi archwire sample groups and the metal bracket and uncoated NiTi archwire sample groups (P= 0.01). The adherence of <i>Lactobacillus acidophilus</i> to the ceramic bracket and uncoated NiTi archwire group was higher than the metal bracket and coated NiTi archwire group, and the metal bracket and uncoated NiTi archwire group. The attachment of <i>Lactobacillus acidophilus</i> to the metal bracket and uncoated NiTi archwire groups was the lowest of all sample groups in this study.</p><p><strong>Conclusion: </strong>The highest <i>Lactobacillus acidophilus</i> adherence was in the ceramic bracket with coated NiTi archwire group compared to the other three groups.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 22","pages":"106-110"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitudes, and Practices in Colorectal Cancer Screening in the Philippines.","authors":"Joseff Karl U Fernandez, Martin Augustine B Borlongan, Michael Anthony A Baliton, Dennis L Sacdalan, Florge Francis A Sy, Analigaya R Agoncillo, Carl Lawrence C Arenos, Vincent F Tatoy, Timothy Joseph S Uy, Isabela Andrea L Reveldez, Steven Johnson L Lim","doi":"10.47895/amp.vi0.8608","DOIUrl":"https://doi.org/10.47895/amp.vi0.8608","url":null,"abstract":"<p><strong>Background and objective: </strong>Colorectal cancer (CRC) has the third highest incidence in the Philippines. Currently, there is a paucity in literature that is focused on the knowledge, attitudes, and perceptions of Filipinos regarding CRC screening. This is the first study in the Philippines that describes this.</p><p><strong>Methods: </strong>This is a cross-sectional study that validated a 52-item Filipino questionnaire on the knowledge on colorectal cancer, willingness to undergo CRC screening, and perceived benefits and barriers to fecal occult blood test (FOBT) and colonoscopy. The study enrolled household heads more than 20 years of age residing in both urban and rural communities in the Philippines.</p><p><strong>Results: </strong>The UP-PGH CRC KAP (University of the Philippines - Philippine General Hospital Colorectal Cancer Knowledge, Attitudes, and Practices) and Rawl Questionnaire's validity and internal consistency were established in a pilot study of 30 respondents. A total of 288 respondents were then enrolled to the main study group with a median age of 54.0. Knowledge scores for prognosis and utility of CRC screening were modest (6.3/12 and 8.4/20, respectively). Perceived benefit scores to FOBT and colonoscopy were high (9.9/12 and 13.9/16, respectively). Median scores to barriers to FOBT and colonoscopy were intermediate (22.5/36 and 35.8/60, respectively). Notably, a vast majority (86.1%) were willing to participate in CRC screening programs initiated by the government, and 46.9% agreed to undergo screening tests even as out-of-pocket expense.</p><p><strong>Conclusion: </strong>The UP-PGH CRC KAP Questionnaire as well as the Filipino translation of the Rawl Questionnaire are reliable and valid tools in extensively assessing the knowledge of Filipinos on CRC and willingness to undergo screening, as well as the benefits of and barriers to FOBT and colonoscopy. Knowledge scores were modest suggesting that directed educational campaigns and awareness programs can aid in increasing awareness about CRC and its screening. Household income and highest educational attainment were significantly positively correlated with knowledge scores, and perceived benefits of and barriers to CRC screening. Scores were generally comparable between urban and rural communities.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 22","pages":"77-91"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Pulmonary Complications following Adenotonsillectomy in Pediatric Patients with Obstructive Sleep Apnea in a Tertiary Government Hospital.","authors":"Jerilee E Cledera, Maria Cristina H Lozada, Kevin L Bautista","doi":"10.47895/amp.vi0.7231","DOIUrl":"10.47895/amp.vi0.7231","url":null,"abstract":"<p><strong>Objective: </strong>Our study aimed to identify and describe pulmonary complications and its associated risk factors in children with suspected or confirmed obstructive sleep apnea (OSA) who underwent tonsillectomy or adenotonsillectomy in a tertiary government hospital.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study. Medical charts of pediatric patients with suspected or confirmed OSA who were admitted for tonsillectomy or adenotonsillectomy from January 1, 2016 to December 31, 2020 were retrieved and reviewed. Information of the individual patients including the demographic data, clinical profile, polysomnography results, and presence of postoperative pulmonary complications were recorded. Descriptive statistics was utilized to present continuous data while frequency and percentage for categorical data. Fisher exact test was used to compare the demographic profile of patients with postoperative pulmonary complications from those without.</p><p><strong>Results: </strong>A total of 90 patient records were analyzed. The mean age of the patient population was 7.87 years, 55.6% were male, 17.8% of patients were classified as obese. Thirty-four children had preoperative polysomnography and of these, 47.1% were classified as severe. Only two (2.2%) patients had postoperative pulmonary complications, which were bronchospasm and desaturation, respectively. There were no statistically significant differences noted in comparing the clinicodemographic profile of patients with postoperative pulmonary complications from those without complications.</p><p><strong>Conclusion: </strong>Our results showed that most pediatric patients with suspected or confirmed OSA who underwent adenotonsillectomy did not have pulmonary complications.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 22","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promises and Realities of Electronic Health Information System in the Philippines.","authors":"Arturo M Ongkeko","doi":"10.47895/amp.v58i22.12364","DOIUrl":"10.47895/amp.v58i22.12364","url":null,"abstract":"","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 22","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are Primary Care Practitioners Ready for Evidence-based Clinical Practice?","authors":"Juliet Sio Aguilar","doi":"10.47895/amp.v58i21.12253","DOIUrl":"https://doi.org/10.47895/amp.v58i21.12253","url":null,"abstract":"","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 21","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Resistance, Aerobic, and Concurrent Aerobic and Resistance Exercises on Inflammatory Markers of Metabolically Healthy Overweight or Obese Adults: A Systematic Review and Meta-analysis.","authors":"John Patrick R Lentejas, Mark Anthony S Sandoval, Teresita Joy Ples Evangelista, Myrna D Buenaluz-Sedurante, Clarissa L Velayo","doi":"10.47895/amp.vi0.7315","DOIUrl":"https://doi.org/10.47895/amp.vi0.7315","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the effectiveness of different exercise interventions on improving adiposity-related inflammatory markers of metabolically healthy obese (MHO) adults.</p><p><strong>Methods: </strong>This is a systematic review with meta-analysis of randomized controlled trials (RCTs) and quasi-experimental studies on the effects of exercise interventions in the inflammatory markers of sedentary adults with MHO phenotype. Systematic searches were performed in PubMed, Cochrane, CINAHL, and OVID from January 2021 to January 2022. The included studies were from 2000 to 2021. The inclusion criteria included: a) adults with obese phenotype, b) has physical activity or exercise as intervention, and c) inflammatory markers as outcome measure. Exclusion criteria included: a) pregnant women, b) adults with cardiovascular conditions or taking medications, c) participants having central obesity. The review was registered on PROSPERO (CRD42021249661). Risk of bias (RoB) assessment was performed using Revised Cochrane RoB tool for RCTs, and ROBINS-I tool for quasi-experimental studies. A meta-analysis was performed for inflammatory markers and body composition measurements using random effects model with forest plots presenting mean differences (MD) of outcome measures with 95% CI.</p><p><strong>Results: </strong>Twenty-one RCTs and seven quasi-experimental studies with 1,117 participants were included in the review. For short-term intervention, aerobic exercises showed an increased trend in IL-6 levels, and both resistance and aerobic exercises reduced TNF-alpha and CRP levels, respectively. For long-term exercises, aerobic exercises showed a significant reduction in CRP (MD= -0.33, 95%CI, -0.57 to -0.09, p=0.006). Long-term concurrent training also showed a significant reduction in TNF-alpha (MD= -2.65, 95%CI, -4.13 to -1.18; p=0.0004). Meta-regression also found no direct association between body weight and fat mass, and changes in inflammatory markers.</p><p><strong>Conclusion: </strong>Concurrent and aerobic exercises were both effective in reducing pro-inflammatory markers. Concurrent training was more effective in reducing BMI, body fat composition, and CRP compared to aerobic and resistance exercises. Furthermore, middle-aged women benefited from aerobic exercises to reduce IL-6 levels. These results indicate the need for both resistance and aerobic exercise in improving inflammatory levels of the body. This review has limitations in terms of degree of heterogeneity brought by different exercise protocol and assessment of inflammatory markers. More research is needed to identify possible outcome measures that can predict chronic inflammation in MHO people.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 21","pages":"90-105"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Students' Perceived Counseling Behavior and Feedback on a University-led Patient Medication Counseling Program Implemented in a Tertiary Government Hospital.","authors":"Frances Lois U Ngo, Camille Francesca T Cadag, Jan Redmond V Ordoñez","doi":"10.47895/amp.vi0.8335","DOIUrl":"https://doi.org/10.47895/amp.vi0.8335","url":null,"abstract":"<p><strong>Background and objectives: </strong>Pharmacists are in a unique position to provide important medication information, prevent errors, and help improve patient outcomes. Patient medication counseling (PMC) is integral in medication therapy management of pharmacists. Students perceive PMC as an important step in ensuring the most appropriate pharmacotherapy for the patients and as an essential component of drug management. The objective of the study is to describe the students' perceptions on a university-led patient medication counseling program implemented in a patient medication counseling course.</p><p><strong>Methods: </strong>The study employs a qualitative study design with a total population sampling of forty-two (42) Clin Pharm 176 BS Pharmacy students in a College of Pharmacy. A self-evaluation adapted from the United States Pharmacopeia medication counseling behavior guidelines (USP-MCBG) scale was performed which has with four components: needs assessment, precautions and warnings, management of the treatment, and communication. A synthesis session was conducted utilizing a semi-structured questionnaire. The data was analyzed using measures of central tendency and thematic analysis.</p><p><strong>Results: </strong>Forty-two (42) students answered the USP-MCBG scale and participated in the synthesis session. Participants rated highest in communication (88.81 ± 8.78) and lowest in treatment management (79.49 ± 12.90) which suggests that the students were better equipped in displaying effective nonverbal behaviors and using appropriate language but were least confident in developing and managing treatment plans. There were five main domains on how the students evaluated the course and the PMC program which include pre-counseling session requirements, challenges in patient interaction, interprofessional collaboration, professional outlook, and program recommendations.</p><p><strong>Conclusion: </strong>A university-led PMC program is effective in providing training for student pharmacists to identify and provide recommendations on medication therapy problems, and to practice interprofessional collaboration. It is recommended to continue the student training in the PMC program and to integrate this in the student internship program to evaluate the skills development of students during their clinical rotations.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 21","pages":"30-39"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting Outcomes of Percutaneous Transluminal Angioplasty for Central Vein Occlusive Disease in the University of the Philippines-Philippine General Hospital: A 10-Year Experience.","authors":"Eduardo R Bautista, Pocholo Carlo R Bernardo, Adrian E Manapat, Leoncio L Kaw, Alduz Inri S Cabasa","doi":"10.47895/amp.vi0.8542","DOIUrl":"https://doi.org/10.47895/amp.vi0.8542","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To describe the treatment outcomes of patients who underwent Percutaneous Transluminal Angioplasty (PTA) for Central Vein Occlusive Disease (CVOD) in end-stage kidney disease and determine the association between patient profile and treatment outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A single-institution, retrospective review of patients aged 18 and above with end-stage kidney disease who underwent PTA for CVOD in the University of the Philippines - Philippine General Hospital (UP-PGH) from January 1, 2013, to December 31, 2022, was performed. These patients' demographic and clinical profiles were evaluated using means, frequencies, and percentages. The relationship between patient profile and success of PTA was assessed using Chi-square and Mann-Whitney U tests.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;One hundred one patients were included in the study. Eighty-two had a first intervention, and 19 had a recurrent first intervention. The mean age was 49.8 years, with forty-six (45.5%) males and fifty-five (54.5%) females. The most common comorbidity was hypertension (59.4%). This was followed by diabetes (35.6%), chronic glomerulonephritis (18.8%), and NSAID nephropathy (4.9%). Other comorbidities include lupus nephritis, urate nephropathy, and polycystic kidney disease. The interval between symptoms and intervention ranged from two weeks to ninety-six weeks. Eleven patients (10.9%) had an arterio-venous fistula (AVF) before initiating dialysis and did not have a history of dialysis catheter use. Temporary catheters comprise most of the central vein catheters (CVC) (84.2%), while tunneled catheters were a minority (8.9%). The overall central line insertions of one hundred one patients were one hundred fifty-five, most via the right internal jugular vein (86%). There was a total of one hundred twenty-seven lesions seen during venography. Most of these lesions were in the left Innominate vein (38.6%, 39/101) and the right innominate vein (32.7%, 33/101). The most common type of lesion was stenosis (47.5%), followed by abrupt occlusions (31.7%) and tapered occlusions (20.8%). The overall success rate of PTA was 74.2%. In the second intervention for recurrence (n=19), the success rate was 78.9% (15/19). Third-time intervention in three patients was all successful. The success rate in stenotic, tapered, and abrupt lesions were 100%, 85.7%, and 28.1%, respectively. Symptom-free intervals ranged from twelve to one hundred ninety-two weeks. After a failed intervention, a new fistula or graft was the most common access option (50%). This was followed by central catheter (38.5%), venous bypass (7.7%), and peritoneal dialysis catheter (3.8%). Morbidity was 0.99%. The in-hospital mortality was zero.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Overall PTA success rate for non-recurrent and first operation of recurrent patients with CVOD was high (74%). Stenotic type of lesions were the best vessels to dilate. Failure of PTA was directly related t","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 21","pages":"40-48"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}