中国针灸最新文献

{"title":"[Mechanism of acupuncture on cerebral ischemia-reperfusion injury via p53/SLC7A11/GPX4 signaling pathway in rat models].","authors":"Qi Wang, Ziwen Hou, Yaoyao Liu, Dan Wei, Qingjie Kong, Xia Chen","doi":"10.13703/j.0255-2930.20240703-k0003","DOIUrl":"10.13703/j.0255-2930.20240703-k0003","url":null,"abstract":"<p><strong>Objective: </strong>To explore the neuroprotective effect and underlying mechanism of <i>Xingnao Kaiqiao</i> acupuncture (acupuncture for regaining consciousness and opening orifices) in the rat models of cerebral ischemia-reperfusion injury (CIRI) based on the p53 protein (p53)/solute carrier family 7 member 11 (SLC7A11)/glutathione peroxidase 4 (GPX4) signaling pathway.</p><p><strong>Methods: </strong>Of 102 male Wistar rats, 20 rats were randomly collected as a sham-operation group. Using a modified external carotid artery filament insertion method, CIRI models were prepared by occluding the middle cerebral artery in the rest rats. After modeling and excluding 1 non-successfully modeled rat and 1 dead one, the other modeled rats were randomized into a model group, an agonist group, an acupuncture group, and an acupuncture + agonist group, 20 rats in each one. <i>Xingnao Kaiqiao</i> acupuncture therapy was delivered in the rats of the acupuncture group and the acupuncture + agonist group. The acupoints included \"Shuigou\" (GV26), bilateral \"Neiguan\" (PC6), and \"Sanyinjiao\" (SP6) on the affected side. Electroacupuncture was attached to \"Neiguan\" (PC6) and \"Sanyinjiao\" (SP6) on the affected side, with dense-disperse wave, a frequency of 2 Hz/15 Hz and intensity of 1 mA. The intervention was delivered twice daily, 20 min each time and for 7 consecutive days. In the agonist group and acupuncture+agonist group, p53 agonist, COTI-2 was intraperitoneally injected (15 mg/kg), once daily for 7 consecutive days. Neurological deficit was evaluated using Zausinger's six-point scale. Cerebral infarction volume was quantified by triphenyl tetrazolium chloride (TTC) staining. Histopathological changes were observed using hematoxylin-eosin (HE) staining. Iron deposition was assessed by Prussian blue staining. Mitochondrial ultrastructure in the ischemic cortex was examined under transmission electron microscopy (TEM). Serum iron (Fe<sup>2+</sup>) was measured with chromometry. Malondialdehyde (MDA) and glutathione (GSH) levels in the ischemic hippocampus were determined using thiobarbituric acid and microplate assays, respectively. The mean fluorescence intensity of reactive oxygen species (ROS) in the ischemic cortex was analyzed by flow cytometry. The mRNA and protein expression of GPX4, SLC7A11, and p53 in the ischemic hippocampus were evaluated using quantitative real-time PCR (qRT-PCR) and Western blotting, respectively.</p><p><strong>Results: </strong>Compared with the sham-operated group, the model group exhibited the decrease in neurological deficit score (<i>P</i><0.01), and the increase in cerebral infarction volume percentage (<i>P</i><0.01). The changes of brain tissue were presented in extensive cellular necrosis, pyknotic and deeply-stained nuclei, and vacuolar degeneration. The iron deposition was elevated in cortex and hippocampus (<i>P</i><0.01), mitochondrial membrane density increased, the cristae was broken or reduced, and the out","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1099-1110"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effects of electroacupuncture on cognitive impairment and mitophagy mediated by KIF5A/Miro1 pathway in Parkinson's disease mice].","authors":"Mengzhu Li, Jiafan Chen, Mengxuan Chen, Haiyan Li, Zhenyi Zhang, Da Gao, Weicong Zeng, Lijun Zhao, Meiling Zhu","doi":"10.13703/j.0255-2930.20250227-k0004","DOIUrl":"10.13703/j.0255-2930.20250227-k0004","url":null,"abstract":"<p><strong>Objective: </strong>To explore the improvement effect of electroacupuncture (EA) based on <i>Xingnao Kaiqiao</i> acupuncture (acupuncture for regaining consciousness and opening orifices) on cognitive impairment in mice with Parkinson's disease (PD), and to explore its regulatory mechanisms on the kinesin family member 5A (KIF5A)/mitochondrial Rho GTPase 1 (Miro1) pathway and mitophagy in prefrontal cortical neurons.</p><p><strong>Methods: </strong>A total of 70 male C57BL/6J mice of clean grade were randomly divided into a normal group (12 mice), a sham operation group (12 mice), and a model pre-screening group (46 mice). Unilateral stereotaxic injection of 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle was adopted to establish the PD model in the model pre-screening group. Twenty-four mice after successful modeling were randomly selected and divided into a model group and an EA group, 12 mice in each one. In the EA group, acupuncture was applied at \"Shuigou\" (GV26) and bilateral \"Sanyinjiao\" (SP6) and \"Neiguan\" (PC6), ipsilateral \"Sanyinjiao\" (SP6) and \"Neiguan\" (PC6) were connected to EA respectively, with disperse-dense wave, 5 Hz/20 Hz in frequency, 0.5 mA in current intensity, 20 min a time, 6 times a week for 30 days. Cognitive function was assessed by Y-maze and Morris water maze tests; morphology of prefrontal cortex was observed by H.E. staining; reactive oxygen species (ROS) level in prefrontal cortex was detected by fluorescence probe method; mitochondrial morphology and autophagosome ultrastructure were observed by transmission electron microscopy; the mRNA expression of tyrosine hydroxylase (TH) was detected by quantitative real-time PCR; the protein expression of TH, KIF5A, Miro1, p62, Parkin and PTEN induced kinase 1 (PINK1) was detected by Western blot.</p><p><strong>Results: </strong>Compared with the sham operation group, both the model group and the EA group exhibited increased rotation number of per minute (<i>P</i><0.001). Compared with the sham operation group, in the model group, the novel arm exploration time of Y-maze test was shortened (<i>P</i><0.001), the escape latency of Morris water maze test was prolonged (<i>P</i><0.05) and the platform crossing number of Morris water maze test was reduced (<i>P</i><0.01); in the prefrontal cortex, the number of cellular vacuole and neurons with karyopyknosis was increased (<i>P</i><0.001), and mitochondrial autophagosomes could be observed; in the prefrontal cortex, the relative expression of ROS was increased (<i>P</i><0.001), the protein and mRNA expression of TH was decreased (<i>P</i><0.001), the protein expression of Miro1, PINK1, Parkin was increased (<i>P</i><0.001, <i>P</i><0.01), the protein expression of KIF5A and p62 was decreased (<i>P</i><0.001). Compared with the model group, in the EA group, the novel arm exploration time of Y-maze test was prolonged (<i>P</i><0.01), the escape latency of Morris water maze test was shortened (<i>P</i><0.05)","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1111-1119"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Moxibustion for central obesity with phlegm-dampness constitution: a randomized controlled trial].","authors":"Yanji Zhang, Dan Wei, Wei Huang, Jiajie Wang, Xia Chen, Chengwei Fu, Benlu Yu, Yingrong Zhang, Zhongyu Zhou","doi":"10.13703/j.0255-2930.20240906-k0002","DOIUrl":"10.13703/j.0255-2930.20240906-k0002","url":null,"abstract":"<p><strong>Objective: </strong>To observe the efficacy and safety of moxibustion in treating patients with central obesity of phlegm-dampness constitution.</p><p><strong>Methods: </strong>A total of 66 patients with central obesity of phlegm-dampness constitution were randomly assigned to a moxibustion group (<i>n</i>=33, 3 cases dropped out) and a sham moxibustion group (<i>n</i>=33, 4 cases dropped out). The moxibustion group received mild moxibustion combined with lifestyle intervention; the moxibustion was applied at Shenque (CV8) and bilateral Zusanli (ST36), 30 min per session, maintaining a local skin temperature of (43±1) ℃. The sham moxibustion group received simulated moxibustion combined with lifestyle intervention; the simulated moxibustion was applied at the same acupoints, with the same session length, but with a maintained skin temperature of (37±1) ℃. Both groups were treated once every other day, three times per week for 8 consecutive weeks. Obesity-related physical indicators (waist circumference, hip circumference, body weight, body fat percentage, body mass index [BMI]), constitution evaluation indicators (phlegm-dampness constitution conversion score, symptom score), the impact of weight on quality of life-lite (IWQOL-Lite), the hospital anxiety and depression scale (HADS), and the incidence of adverse events were measured before and after treatment, and after 4 weeks of follow-up.</p><p><strong>Results: </strong>Compared with before treatment, both groups showed significant reductions in waist circumference, hip circumference, body weight, body fat percentage, BMI, phlegm-dampness constitution conversion score and symptom score, IWQOL-Lite, and both anxiety and depression subscale scores of HADS after treatment and at follow-up (<i>P</i><0.001). These improvements were significantly greater in the moxibustion group than those in the sham moxibustion group (<i>P</i><0.001, <i>P</i><0.01, <i>P</i><0.05). One patient in the moxibustion group experienced a mild burn that resolved with routine care; the incidence of adverse reactions was 3.0% (1/33) in the moxibustion group and 0% (0/33) in the sham moxibustion group, with no statistically significant difference (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>On the basis of lifestyle intervention, moxibustion effectively improves obesity-related physical indicators, enhances quality of life, alleviates anxiety and depression, and improves the phlegm-dampness constitution in patients with central obesity. These benefits persist for at least 4 weeks after treatment.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1053-1060"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Heat-sensitive moxibustion robot for improving depressive state in methamphetamine addicts during withdrawal period: a randomized controlled trial].","authors":"Yuexia Jiang, Haiyan Li, Wei He, Jing Zhou, Chunliang Zou, Dingyi Xie, Rixin Chen","doi":"10.13703/j.0255-2930.20250402-k0001","DOIUrl":"10.13703/j.0255-2930.20250402-k0001","url":null,"abstract":"<p><strong>Objective: </strong>To observe the clinical efficacy of heat-sensitive moxibustion robot for improving the depressive state of methamphetamine addicts during withdrawal period.</p><p><strong>Methods: </strong>A total of 60 patients with methamphetamine addiction accompanied with depressive state were randomly divided into an observation group (40 cases, 4 cases dropped out) and a control group (20 cases, 2 cases dropped out). The control group received routine health education and addiction treatment in compulsory isolation drug rehabilitation center. On the basis of the treatment in the control group, in the observation group, the heat-sensitive moxibustion robot was used to locate sensitive points at the Shenque (CV8) and Danzhong (CV17), and dual-point sparrow-pecking moxibustion was delivered for 60 min per session. The moxibustion therapy was performed 4 times in the 1st week, 3 times in the 2nd and 3rd weeks respectively, and 2 times in the 4th week, for 12 times totally. The scores of Hamilton depression scale (HAMD), self-rating depression scale (SDS), visual analogue scale (VAS) for drug craving, Hamilton anxiety scale (HAMA), self-rating anxiety scale (SAS), and Pittsburgh sleep quality index (PSQI) were observed before treatment, at the end of the 2nd and 4th weeks of treatment, and 4 weeks after the treatment completion (follow-up) in the two groups.</p><p><strong>Results: </strong>At each time point after treatment, in the observation group, the HAMD, VAS, HAMA and PSQI scores were decreased compared with those before treatment (<i>P</i><0.01, <i>P</i><0.001); at the end of the 4th week of treatment and in follow-up, the SDS and SAS scores were decreased compared with those before treatment (<i>P</i><0.001, <i>P</i><0.01). Compared before treatment, there were no significant differences in the above scores at each time point after treatment in the control group (<i>P</i>>0.05). In the observation group, at each time point after treatment, the HAMD and VAS scores were lower than those in the control group (<i>P</i><0.01, <i>P</i><0.001, <i>P</i><0.05); at the end of the 4th week of treatment and in follow-up, the SDS and HAMA scores were lower than those in the control group (<i>P</i><0.05, <i>P</i><0.001); at the end of the 4th week of treatment, the PSQI score was lower than that in the control group (<i>P</i><0.01).</p><p><strong>Conclusion: </strong>Heat-sensitive moxibustion robot effectively improves depression, anxiety and sleep quality, and reduces drug craving in methamphetamine addicts during withdrawal period.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1061-1067"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Academic characteristics of acupuncture and moxibustion of <i>Qilu</i> medical masters in Ming and Qing dynasties and its influence on later generations].","authors":"Hong Guan, Jian Wang","doi":"10.13703/j.0255-2930.20240925-k0003","DOIUrl":"10.13703/j.0255-2930.20240925-k0003","url":null,"abstract":"<p><p>The biography, medical writings and family lineages of <i>Qilu</i> medical masters in the Ming and Qing dynasties were collected and collated, so as to analyze their contributions to expounding acupuncture and moxibustion theories, practicing medical ethics and morals, and academic inheritance in later generations; as well as exploring the valuable guidance to clinical practice of modern acupuncture and moxibustion. <i>ZHAI Liang</i>, <i>YUE Hanzhen</i>, <i>HUANG Yuanyu</i> and <i>LIU Kui</i> were representatives of <i>Qilu</i> masters in the Ming and Qing dynasties. They showed their respects on classics with high inclusion, laid stress on elaboration and innovation in theories and practice of meridians, acupoints and acupuncture technique specially. Based on family heritage and apprenticeship, not only the academic school of acupuncture-moxibustion with regional characteristics had been cultivated, but also the important foundation been laid for the perfection of acupuncture-moxibustion diagnosis and treatment system in later generations. The integration of medical ethics and medical skills showed the spirit of \"the benevolence of a doctor\". These masters devoted themselves to the collation and research of medical books, collected the classics of medical masters, and wrote a number of easily-learned popular works for clinical application to benefit future generations.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1171-1179"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[International education of Chinese acupuncture-moxibustion in cross-cultural dialogue: integration of clinic, culture and language].","authors":"Qian Wang, Zhigang Lv","doi":"10.13703/j.0255-2930.20240711-0003","DOIUrl":"10.13703/j.0255-2930.20240711-0003","url":null,"abstract":"<p><p>This paper focuses on the necessity and feasibility of the multidimensional integration of clinic, culture and language in the international education of acupuncture-moxibustion within a cross-cultural context. In view of the current gap between theory and practice, and the barrier of culture and language in the international education of acupuncture-moxibustion, it proposes the specific integration approaches, such as the \"trinity teaching method\" and \"modularization of acupuncture courses\", which develops the framework of international education of acupuncture-moxibustion, guided by \"cultural exploration\" in macroscopic view and implemented through \"cultural experience\", aiming to achieve a seamless integration of clinic, culture, and language. This initiative not only inherits and promotes Chinese acupuncture-moxibustion, maintains its unique position in global healthcare, but also fosters dialogue and exchange between Eastern and Western medicine. Ultimately, it enhances the international recognition of Chinese acupuncture-moxibustion. By offering fresh perspectives and methodologies, this paper paves the way for a more comprehensive and systematic approaches to international education of acupuncture-moxibustion, presenting the theoretical and practical significance in advancing the globalization of traditional Chinese medicine.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1146-1152"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Dose-effect relationship between the number of acupuncture sessions and efficacy for cervical vertigo: a Meta-regression analysis based on randomized controlled trials].","authors":"Yixuan Zhang, Rui Yang, Chunchang Zhang, Lin Han","doi":"10.13703/j.0255-2930.20240711-0002","DOIUrl":"10.13703/j.0255-2930.20240711-0002","url":null,"abstract":"<p><strong>Objective: </strong>To explore the dose-effect relationship between the number of acupuncture sessions and the efficacy for cervical vertigo (CV).</p><p><strong>Methods: </strong>Literature regarding randomized controlled trials (RCTs) of acupuncture for CV was retrieved from CNKI, Wanfang, VIP, Web of Science, and PubMed databases from inception to June 28th, 2024. Studies were included if patients were treated solely with acupuncture and the core prescription included Baihui (GV20)-Fengchi (GB20)-neck-jiaji (EX-B2). Outcomes included the evaluation scale for cervical vertigo symptoms and function (ESCV) score and the mean blood flow velocity of vertebrobasilar arteries. The Cochrane risk of bias assessment tool 2.0 was used to evaluate study quality. Dose-effect Meta-regression analysis was performed using the robust-error Meta-regression (REMR) method in Stata 17.0 software.</p><p><strong>Results: </strong>Nineteen RCTs were included with a total of 747 patients in the experimental groups. After 10 sessions of acupuncture, the ESCV score increased to 20.29 (95% <i>CI</i>: 16.77, 23.80), with a pre-post ESCV difference of 4.60 (95% <i>CI</i>: 2.59, 6.60) and an improvement rate of 0.36 (95% <i>CI</i>: 0.26, 0.46). After 20 sessions of acupuncture, the ESCV score increased to 21.55 (95% <i>CI</i>: 18.87, 24.22), with a difference of 5.42 (95% <i>CI</i>: 3.87, 6.97) and an improvement rate of 0.39 (95% <i>CI</i>: 0.31, 0.48). After 10 sessions of acupuncture, the improvement rates for left vertebral artery (LVA), right vertebral artery (RVA), and basilar artery (BA) mean blood flow velocities were 0.08 (95% <i>CI</i>: 0.05, 0.12), 0.09 (95% <i>CI</i>: 0.05, 0.12), and 0.11 (95% <i>CI</i>: 0.06, 0.15), respectively. After 14 sessions of acupuncture, the improvement rates reached their peaks: LVA [0.09 (95% <i>CI</i>: 0.06, 0.12)], RVA [0.10 (95% <i>CI</i>: 0.07, 0.13)], and BA [0.12 (95% <i>CI</i>: 0.07, 0.16)].</p><p><strong>Conclusion: </strong>A nonlinear dose-effect relationship existed between the number of acupuncture sessions and the efficacy for CV. Fourteen sessions were recommended as the optimal number of acupuncture treatments.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1180-1186"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux for gastroesophageal reflux cough: a randomized controlled trial].","authors":"Mingjie Tang, Wen Lu, Xiaoni Zhang, Jiawei Gao, Xinchang Wei, Jin Lu, Jia Zhu, Yulu Feng, Lejing Jiao, Xiaofang Xia, Zhi Zhou, Zhaoming Chen","doi":"10.13703/j.0255-2930.20241225-k0001","DOIUrl":"10.13703/j.0255-2930.20241225-k0001","url":null,"abstract":"<p><strong>Objective: </strong>To observe the clinical efficacy of acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux for gastroesophageal reflux cough (GERC).</p><p><strong>Methods: </strong>A total of 120 GERC patients were randomly assigned to an observation group (60 cases, 1 case dropped out) and a control group (60 cases, 1 case was eliminated). The observation group received acupoint thread-embedding treatment at positive response points of governor vessel. If no such points were detected, the following acupoints were used: Dazhui (GV14), Fenghu (Extra), Shendao (GV11), Lingtai (GV10), and Zhiyang (GV9). Treatment was administered once every two weeks. The control group received oral rabeprazole enteric capsules at 20 mg twice daily. All the treatment was given for 6 weeks. Clinical outcomes were assessed using cough symptom score, reflux disease questionnaire (RDQ) score, and Leicester cough questionnaire (LCQ) score before and after treatment in the two groups. Clinical efficacy was also compared between the two groups.</p><p><strong>Results: </strong>After treatment, both groups showed decreased cough symptom scores and the each item scores and total scores of RDQ (<i>P</i><0.001), and increased LCQ scores (<i>P</i><0.001) compare with those before treatment. The observation group exhibited lower cough symptom score and chest pain, reflux and total score of RDQ, and higher LCQ score compared to those in the control group (<i>P</i><0.05). The total effective rate in the observation group was 94.9% (56/59), which was higher than 84.7% (50/59) in the control group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Acupoint thread-embedding therapy of regulating governor vessel, dispersing lung, and suppressing reflux could effectively alleviate cough and reflux symptoms in patients with GERC and improve their quality of life.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1047-1052"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effect of acupuncture at Jiaji (EX-B2) points on upper limb motor dysfunction after stroke].","authors":"Jingxiang Zhuang, Xiaotong Chen, Chuanliang Ruan, Huirong Lei, Guifen Chen, Pingping Zeng","doi":"10.13703/j.0255-2930.20240627-0001","DOIUrl":"10.13703/j.0255-2930.20240627-0001","url":null,"abstract":"<p><strong>Objective: </strong>To observe the effect of acupuncture at Jiaji (EX-B2) points on upper limb motor dysfunction in patients after stroke.</p><p><strong>Methods: </strong>A total of 62 patients with upper limb motor dysfunction after stroke were randomly assigned to an observation group (<i>n</i>=31, 3 cases dropped out) and a control group (<i>n</i>=31, 2 cases dropped out). Both groups received routine medical treatment and rehabilitation training. The control group was treated with conventional acupuncture at the affected side's Jianyu (LI15), Quchi (LI11), Shousanli (LI10), Huantiao (GB30), Yanglingquan (GB34), and Zusanli (ST36) etc. On this basis, the observation group received additional acupuncture at the affected side's Jiaji points from C₄ to T₅. Treatment was administered once daily, five times a week, for four weeks. Motor evoked potential (MEP) latency and amplitude of the abductor pollicis brevis and abductor digiti minimi, Fugl-Meyer assessment for upper extremity (FMA-UE), and Wolf motor function test (WMFT) scores were compared before and after treatment in the two groups.</p><p><strong>Results: </strong>After treatment, both groups showed increased MEP amplitudes and decreased latencies of the abductor pollicis brevis and abductor digiti minimi (<i>P</i><0.05), as well as increased FMA-UE and WMFT scores (<i>P</i><0.05); the observation group had greater MEP amplitudes, shorter latencies, and higher FMA-UE and WMFT scores compared to the control group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Acupuncture at Jiaji (EX-B2) points could enhance the excitability of upper limb motor neural pathways in upper limb motor dysfunction after stroke patients, thereby promoting motor function recovery of the upper limb.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1037-1041"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Press needle exercise therapy for stable chronic obstructive pulmonary disease: a randomized controlled trial].","authors":"Ping Yang, Wei Xu, Tian Fu","doi":"10.13703/j.0255-2930.20240725-0001","DOIUrl":"10.13703/j.0255-2930.20240725-0001","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical efficacy of press needle exercise therapy for stable chronic obstructive pulmonary disease (COPD).</p><p><strong>Methods: </strong>Sixty patients with stable COPD were randomly assigned to an observation group (30 cases, 1 case dropped out) and a control group (30 cases, 2 cases dropped out). Basic treatment was applied to the two groups. The control group received pulmonary rehabilitation training, while the observation group received press needle exercise therapy. Press needle was applied at Dazhui (GV14), Danzhong (CV17), Qihai (CV6), Guanyuan (CV4), Zhiyang (GV9) and bilateral Feishu (BL13), Gaohuang (BL43), Jueyinshu (BL14), Xinshu (BL15), Geshu (BL17), Pishu (BL20), Shenshu (BL23). During the press needle intervention, patients also underwent pulmonary rehabilitation training. Treatments were administered once every other day, three times a week, for 8 weeks. Pulmonary function indexes including forced expiratory volume in the first second (FEV1), FEV1 to forced vital capacity ratio (FEV1/FVC), and percentage of predicted FEV1 (FEV1%) were measured before and after treatment in the two groups. Additional assessments included the 6-minute walk test (6 MWT) and COPD assessment test (CAT) score. Clinical efficacy was also compared between the two groups.</p><p><strong>Results: </strong>After treatment, both groups showed improvements in FEV1, FEV1/FVC, FEV1%, and 6 MWT (<i>P</i><0.05), and reductions in CAT scores (<i>P</i><0.05); the observation group showed higher FEV1, FEV1/FVC, FEV1%, and 6 MWT values, and lower CAT scores compared to those in the control group (<i>P</i><0.05). The total effective rate in the observation group was 86.2% (25/29), higher than 60.7% (17/28) in the control group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Press needle exercise therapy could effectively alleviate clinical symptoms, improve pulmonary function and exercise tolerance, and enhance quality of life in patients with stable COPD.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 8","pages":"1042-1046"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}