中国针灸Pub Date : 2025-09-12Epub Date: 2025-07-14DOI: 10.13703/j.0255-2930.20240823-k0003
Man Zhang, Zhifang Xu, Meidan Zhao, Xiumei Yin, Jiazhu Wu, Zhixin Liu, Yuanhao DU
{"title":"[Electroacupuncture at neuro-arterial stimulation points for post-stroke shoulder-hand syndrome: a randomized controlled trial].","authors":"Man Zhang, Zhifang Xu, Meidan Zhao, Xiumei Yin, Jiazhu Wu, Zhixin Liu, Yuanhao DU","doi":"10.13703/j.0255-2930.20240823-k0003","DOIUrl":"10.13703/j.0255-2930.20240823-k0003","url":null,"abstract":"<p><strong>Objective: </strong>To compare the clinical efficacy of electroacupuncture (EA) at neuro-arterial stimulation points with topical western medication in treating post-stroke shoulder-hand syndrome (SHS).</p><p><strong>Methods: </strong>A total of 72 patients with post-stroke SHS were randomly assigned to an observation group (<i>n</i>=36, 2 cases dropped out) and a control group (<i>n</i>=36, 3 cases dropped out). Both groups received standard neurological treatment, comprehensive rehabilitation, and physical therapy. The observation group received EA at neuro-arterial stimulation points, including the ipsilateral stellate ganglion point, vagus nerve trunk and auricular branch (left side), and stimulation points of the radial and ulnar arteries, radial nerve, ulnar nerve, and median nerve, once daily for 4 weeks. The control group was treated with topical diclofenac diethylamine emulgel, and mucopolysaccharide polysulfate cream was added for patients with pronounced early-stage edema, twice a day for 4 weeks. The VAS pain score and hand edema volume were recorded before treatment, at 2 and 4 weeks during treatment, and 2 weeks after treatment completion (follow-up). Musculoskeletal ultrasound was used to measure the thickness of the dorsal hand and middle finger skin on the affected side before and after 4 weeks of treatment.</p><p><strong>Results: </strong>Compared before treatment, the VAS pain scores and edema volume of the affected hand in both groups were decreased at week 2, week 4, and follow-up (<i>P</i><0.05). At week 4, both groups showed lower VAS pain scores and edema volume than those at week 2 (<i>P</i><0.05); during follow-up, both VAS pain scores and edema volume were further reduced compared to those at week 4 (<i>P</i><0.05). At week 2, week 4, and follow-up, the VAS scores and edema volume of the affected hand in the observation group were lower than those in the control group (<i>P</i><0.05). Compared before treatment, the dorsal hand skin thickness and middle finger skin thickness on the affected side were decreased in both groups after 4 weeks of treatment (<i>P</i><0.05). Compared with the control group, the observation group showed thinner dorsal hand and middle finger skin thickness after 4 weeks of treatment (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>EA at neuro-arterial stimulation points effectively alleviates pain and edema in patients with post-stroke SHS, and demonstrates superior efficacy compared to topical western medication.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1241-1247"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of electroacupuncture on learning and memory abilities in vascular dementia rats via the NCOA4/FTH1 signaling pathway-mediated ferritinophagy].","authors":"Wei Sun, Yinghua Chen, Tong Wu, Hongxu Zhao, Haoyu Wang, Ruiqi Qin, Xiaoqing Su, Junfeng Li, Yuanyu Song, Yue Miao, Xinran Li, Yusheng Han","doi":"10.13703/j.0255-2930.20250220-k0002","DOIUrl":"10.13703/j.0255-2930.20250220-k0002","url":null,"abstract":"<p><strong>Objective: </strong>To observe the effect of electroacupuncture at \"Sishencong\" (EX-HN1) and \"Fengchi\" (GB20) on hippocampal neuronal ferritinophagy mediated by the nuclear receptor coactivator 4 (NCOA4)/ferritin heavy chain 1 (FTH1) signaling pathway in vascular dementia (VD) rats, and to explore the potential mechanisms of electroacupuncture for VD.</p><p><strong>Methods: </strong>A total of 60 male rats of SPF grade were randomly divided into a blank group (12 rats), a sham surgery group (12 rats) and a modeling group (36 rats). In the modeling group, the modified 4-vessel occlusion method was used to establish the VD model. The 24 successfully modeled rats were randomly divided into a model group and an electroacupuncture group, with 12 rats in each group. In the electroacupuncture group, electroacupuncture was applied at left and right \"Sishencong\" (EX-HN1), and bilateral \"Fengchi\" (GB20), with continuous wave, in frequency of 2 Hz and current intensity of 1 mA, 30 min a time, once daily for 21 consecutive days. The learning and memory abilities were assessed using the Morris water maze test before modeling, after modeling and after intervention, as well as the novel object recognition test after intervention. After intervention, the neuronal morphology in the hippocampus was observed by Nissl staining; the iron deposition was observed by Prussian blue staining; the reactive oxygen species (ROS) level was detected by dihydroethidium (DHE) fluorescence staining; the levels of iron, malondialdehyde (MDA) and superoxide dismutase (SOD) in the hippocampal tissue were measured by the colorimetric assay, TBA method, and WST-1 method, respectively; the positive expression of NCOA4, FTH1 and glutathione peroxidase 4 (GPX4) was detected by immunohistochemistry; the protein expression of NCOA4, FTH1, GPX4, and the ratio of microtubule-associated protein 1 light chain 3B (LC3B) Ⅱ/Ⅰ in the hippocampus were detected by Western blot.</p><p><strong>Results: </strong>Compared with the sham surgery group, in the model group, the escape latency was prolonged, and the number of platform crossings reduced (<i>P</i><0.01), the recognition index (RI) was decreased (<i>P</i><0.01); the hippocampal neurons displayed a blurred laminar structure, disorganized cellular arrangement, and the number of Nissl bodies was decreased (<i>P</i><0.01); the percentage of iron deposition area in the hippocampus was increased (<i>P</i><0.01); in the hippocampus, the levels of ROS, iron, MDA, and the protein expression of NCOA4, as well as the LC3B Ⅱ/Ⅰ ratio were increased (<i>P</i><0.01), the SOD level, and the protein expression of FTH1 and GPX4 were decreased (<i>P</i><0.01). Compared with the model group, in the electroacupuncture group, the escape latency was shortened and the number of platform crossings was increased (<i>P</i><0.01), the RI was increased (<i>P</i><0.01); the hippocampal neurons exhibited more regular morphology, better-organized cellular structure","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1271-1280"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-07-25DOI: 10.13703/j.0255-2930.20250117-0001
Jian Kang, Li Li, Shu Wang, Xiaonong Fan, Jie Chen, Jinniu Li, Wenqi Zhang, Yuhe Wei, Ziyi Chen, Jingqi Yang, Jingwen Yang, Chong Su
{"title":"[A machine learning-based trajectory predictive modeling method for manual acupuncture manipulation].","authors":"Jian Kang, Li Li, Shu Wang, Xiaonong Fan, Jie Chen, Jinniu Li, Wenqi Zhang, Yuhe Wei, Ziyi Chen, Jingqi Yang, Jingwen Yang, Chong Su","doi":"10.13703/j.0255-2930.20250117-0001","DOIUrl":"https://doi.org/10.13703/j.0255-2930.20250117-0001","url":null,"abstract":"<p><strong>Objective: </strong>To propose a machine learning-based method for predicting the trajectories during manual acupuncture manipulation (MAM), aiming to improve the precision and consistency of acupuncture practitioner' operation and provide the real-time suggestions on MAM error correction.</p><p><strong>Methods: </strong>Computer vision technology was used to analyze the hand micromotion when holding needle during acupuncture, and provide a three-dimensional coordinate description method of the index finger joints of the holding hand. Focusing on the 4 typical motions of MAM, a machine learning-based MAM trajectory predictive model was designed. By integrating the changes of phalangeal joint angle and hand skeletal information of acupuncture practitioner, the motion trajectory of the index finger joint was predicted accurately. Besides, the roles of machine learning-based MAM trajectory predictive model in the skill transmission of acupuncture manipulation were verified by stratified randomized controlled trial.</p><p><strong>Results: </strong>The performance of MAM trajectory predictive model, based on the long short-term memory network (LSTM), obtained the highest stability and precision, up to 98%. The learning effect was improved when the model applied to the skill transmission of acupuncture manipulation.</p><p><strong>Conclusion: </strong>The machine learning-based MAM predictive model provides acupuncture practitioner with precise action prediction and feedback. It is valuable and significant for the inheritance and error correction of manual operation of acupuncture.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1221-1232"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-06-23DOI: 10.13703/j.0255-2930.20250401-k0004
Huilin Zeng, Bing Liu, Ruixia Wang
{"title":"[Interpretation on the multiple connotations of twelve-meridian differentiation].","authors":"Huilin Zeng, Bing Liu, Ruixia Wang","doi":"10.13703/j.0255-2930.20250401-k0004","DOIUrl":"10.13703/j.0255-2930.20250401-k0004","url":null,"abstract":"<p><p>It attempts to determine the theoretical connotation and clinical application of the twelve-meridian based syndrome/pattern differentiation of TCM through the systematic analysis and elaboration, so as to promote the completion of meridian differentiation system. The exploration is conducted on the main body of traditional meridian-syndrome differentiation, meaning the meridian differentiation in terms of location of illness and that in terms of symptoms. The existing problems and causes are analyzed, and the specific methods of meridian differentiation put forward in line with the characteristics of meridian distribution and symptoms. In reference with <i>Huangdi Neijing</i> (<i>Yellow Emperors</i>' <i>Canon of Medicine</i>) and other ancient literature, the theoretical evidences of meridian differentiation are deeply analyzed in view of physiological/pathological characteristics that has been neglected in the past, such as <i>qi</i> and blood of meridians, opening, closing and pivoting, and time. Additionally, the category issues related to twelve-meridian differentiation and their relationship with six-meridian differentiation are expounded. The summary on the multiple connotations of twelve-meridian differentiation is of great significance on re-understanding meridians, perfecting meridian-collateral differentiation system and improving the accuracy on meridian-based treatment. Besides, the reconstruction of meridian differentiation and its framework is considered profoundly.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1341-1346"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-07-04DOI: 10.13703/j.0255-2930.20240926-k0002
Yiren Bao, Yuanyuan Feng, Rui Wang
{"title":"[Case of red ear syndrome].","authors":"Yiren Bao, Yuanyuan Feng, Rui Wang","doi":"10.13703/j.0255-2930.20240926-k0002","DOIUrl":"10.13703/j.0255-2930.20240926-k0002","url":null,"abstract":"<p><p>This paper reports a case of red ear syndrome, a rare clinical condition, treated with acupuncture. At the initial consultation, the diagnosis was unclear from a western medical perspective. The advantage of traditional Chinese medicine in \"prioritizing symptoms and syndrome differentiation\" was fully utilized. Based on the patient's clinical manifestations, disease progression, tongue and pulse conditions, the treatment addressed the branch by targeting meridian <i>qi</i> stagnation based on the hand-<i>taiyang</i> sinew meridian theory, and treated the root by selecting acupoints according to syndrome differentiation for liver and kidney <i>yin</i> deficiency. A combined treatment of tendon needling and acupuncture produced immediate results after the first session. Subsequent sessions were administered every other day for a total of ten treatments. The patient's ear pain and redness symptoms had nearly disappeared, and a two-month follow-up showed good overall condition.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1338-1340"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-06-26DOI: 10.13703/j.0255-2930.20241009-k0003
Jiping Xu, Jiafu Ji, Lan Zhao, Yuanyuan Zhao, Fan Su
{"title":"[Comparison of the effects of acupuncture with Neiguan(PC6)-to-Waiguan(TE5) and esmolol on hemodynamics during anesthesia induction and postoperative nausea and vomiting].","authors":"Jiping Xu, Jiafu Ji, Lan Zhao, Yuanyuan Zhao, Fan Su","doi":"10.13703/j.0255-2930.20241009-k0003","DOIUrl":"10.13703/j.0255-2930.20241009-k0003","url":null,"abstract":"<p><strong>Objective: </strong>To compare the clinical efficacy of acupuncture with Neiguan (PC6)-to-Waiguan (TE5) and esmolol on hemodynamics during anesthesia induction and postoperative nausea and vomiting.</p><p><strong>Methods: </strong>A total of 100 patients undergoing elective laparoscopic hernia repair or gynecological surgery under general anesthesia were randomly divided into an acupuncture group (50 cases, 3 cases were eliminated) and an esmolol group (50 cases, 2 cases were eliminated). In the acupuncture group, before anesthesia induction, patients were applied to acupuncture with Neiguan (PC6)-to-Waiguan (TE5), and the needles were retained for 15 min on the right side and 30 min on the left side. Patients in the esmolol group were intravenously injected with 20 mg esmolol hydrochloride injection 5 min before anesthesia induction. The systolic blood pressure (SBP) and heart rate (HR) of the two groups were recorded at 5 min after entering the operating room (T<sub>0</sub>), before anesthesia induction (T<sub>1</sub>), after anesthesia induction (T<sub>2</sub>), before tracheal intubation (T<sub>3</sub>) and 1 min after tracheal intubation (T<sub>4</sub>). The visual analogue scale (VAS) scores of pain and the incidence of nausea and vomiting in the two groups were observed at the time of entering postanesthesia care unit (PACU) (T<sub>5</sub>), leaving PACU (T<sub>6</sub>), 6 h after operation (T<sub>7</sub>) and 24 h after operation (T<sub>8</sub>). The dosage of anesthesia-related drugs in the two groups was counted.</p><p><strong>Results: </strong>The SBP and HR of the two groups at T<sub>2</sub>, T<sub>3</sub> and T<sub>4</sub> were lower than those at T<sub>1</sub> (<i>P</i><0.05). SBP and HR at T<sub>3</sub> in the acupuncture group were higher than those in the esmolol group (<i>P</i><0.05). Compared with the esmolol group, in the acupuncture group, the VAS scores of pain at T<sub>6</sub> and T<sub>7</sub> were decreased (<i>P</i><0.05), the incidence of nausea and vomiting at T<sub>7</sub> and T<sub>8</sub> and the nausea and vomiting visual analogue scale (NVAS) scores were decreased (<i>P</i><0.05). Compared with the esmolol group, the dosage of propofol in the acupuncture group was decreased (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Acupuncture with Neiguan (PC6)-to-Waiguan (TE5) can relieve hemodynamic fluctuations during anesthesia induction, reduce postoperative pain and nausea and vomiting, and reduce the dosage of propofol. The curative effect is better than that of esmolol.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1265-1270"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-06-16DOI: 10.13703/j.0255-2930.20250114-k0002
Shiyi Qi, Jinwen Lin, Shihao Wang, Jianguo Chen, Lili Lin, Youcong Ni, Xin DU, Dong Lin
{"title":"[Study on nonlinear spatiotemporal response characteristics of acupoint electrical signals to multi-mode acupuncture and moxibustion stimulation based on array multichannel data].","authors":"Shiyi Qi, Jinwen Lin, Shihao Wang, Jianguo Chen, Lili Lin, Youcong Ni, Xin DU, Dong Lin","doi":"10.13703/j.0255-2930.20250114-k0002","DOIUrl":"10.13703/j.0255-2930.20250114-k0002","url":null,"abstract":"<p><strong>Objective: </strong>To elucidate the rules of temporal and spatial variations in distal skin potential at Hegu (LI4) under different stimulation modes by extracting nonlinear characteristic parameters from array multichannel data and adopting multivariate statistical analysis.</p><p><strong>Methods: </strong>Seven healthy subjects were selected and the surface potential at the left Quchi (LI11) was collected using 14×9 array multichannel electrodes. Using Hegu (LI4) on the left as the stimulation point, four stimulation modes were applied, i.e. being quiescent, point pressing, moxibustion, and manual needling manipulation. Electrical signals were collected for 30 s in each mode, with a 5-min interval between operations, and a sampling frequency of 16 384 Hz. The data was denoised using ensemble empirical mode decomposition (EEMD), and sample entropy (SaEn) features were extracted. Statistical analysis was conducted on these data using factor analysis and multivariate analysis of variance.</p><p><strong>Results: </strong>The SaEn values of most electrode channels were higher under point pressing, moxibustion and manual needling manipulation compared with those under quiescent condition. Under manual needling manipulation, the SaEn value of the electrode channel reached the peak in the first time interval (1-5 s) and it was declining thereafter. Factor analysis showed that the specificity of activation channels was concentrated at the left Quchi (LI11) (loading capacity ≥0.90). Analysis of variance indicated that the significant differences were presented in average sample entropy (SaEn()) values of activation channels among different stimulation modes at Hegu (LI4) (<i>P</i><0.001), but there was no statistically significant interaction effect between groups and time intervals (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Through nonlinear characteristic parameter extraction and multivariate statistical analysis, we have uncovered the complex temporal and spatial dynamical rules of distal skin potential at Hegu (LI4) under various stimulation modes and successfully identified the specific activation characteristics at Quchi (LI11).</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1209-1217"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-05-29DOI: 10.13703/j.0255-2930.20250304-0001
Kefan Li, Tiancheng Xu, Youbing Xia
{"title":"[Seizing the opportunities of the times, moving towards a new era of digital intelligence of acupuncture and moxibustion].","authors":"Kefan Li, Tiancheng Xu, Youbing Xia","doi":"10.13703/j.0255-2930.20250304-0001","DOIUrl":"10.13703/j.0255-2930.20250304-0001","url":null,"abstract":"<p><p>This paper summarizes the historical background of the combination of acupuncture and moxibustion and digital intelligence technology, and its relevant studies in recent years. From three aspects, i.e. meridian points, acupuncture and moxibustion techniques and clinical research, the research status and landing scenarios of such combination, as well as its application value and development prospects were explored. It was found that in the development of digital intelligence of acupuncture and moxibustion, the acupuncture and moxibustion practitioners encountered the insufficient preparation in the coming career situation, the high-level research platforms were few, the cross-interdisciplinary talents were of the shortage, the quantity and quality of data were out of perfection and the study depth and breadth was limited. Focusing on these problems, and associating with the development and research status of the industry, it was attempt to give the analysis and suggestion. In the future, supported by digital intelligence technology to empower acupuncture research, the effect mechanism of acupuncture and moxibustion can be explored in view of more dimensions and deeper levels, and more objective and higher-quality medical evidence can be generated. Eventually, the development of acupuncture and moxibustion industry can be boosted, the modernization of acupuncture and moxibustion and the internationalization of TCM be accelerated.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1195-1200"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-04-27DOI: 10.13703/j.0255-2930.20240903-k0006
Yan Wei, Yuhao Qu, Aihong Yuan, Lele Zhang, Min Ye, Qunwei Li, Hongyu Xie
{"title":"[Moxibustion at different temperatures for cognitive impairment in type 2 diabetes mellitus: a randomized controlled trial].","authors":"Yan Wei, Yuhao Qu, Aihong Yuan, Lele Zhang, Min Ye, Qunwei Li, Hongyu Xie","doi":"10.13703/j.0255-2930.20240903-k0006","DOIUrl":"10.13703/j.0255-2930.20240903-k0006","url":null,"abstract":"<p><strong>Objective: </strong>To observe the effects of moxibustion at different temperatures on cognitive function and blood glucose levels in patients with cognitive impairment associated with type 2 diabetes mellitus (T2DM).</p><p><strong>Methods: </strong>A total of 66 T2DM patients with cognitive impairment were randomly assigned to a high-temperature group (22 cases, 1 case dropped out, 1 case was eliminated), a medium-temperature group (22 cases, 2 cases were eliminated), and a low-temperature group (22 cases, 2 cases were eliminated). All groups received moxibustion at Baihui (GV20), Dazhui (GV14), and Shenting (GV24) based on their existing glycemic control treatment. Moxibustion temperatures were maintained at 44-46 ℃ (high-temperature group), 41-43 ℃ (medium-temperature group), and 38-40 ℃ (low-temperature group), respectively, for 20 min per session, every other day, 3 times a week for 3 months. The Montreal cognitive assessment (MoCA) score, mini-mental state examination (MMSE) score, short-term memory (STM) accuracy and average reaction time, Rey-Osterrieth complex figure (ROCF) score, fasting plasma glucose (FPG), and glycated hemoglobin (HbA1c) were assessed before and after treatment. Clinical efficacy was evaluated after treatment.</p><p><strong>Results: </strong>After treatment, MMSE scores in all three groups were higher than those before treatment (<i>P</i><0.05). In the high-temperature group, the total MoCA score and the scores of visuospatial and executive function, memory and delayed recall, attention, naming, language, and abstraction were higher than those before treatment (<i>P</i><0.05); the scores of ROCF copy, immediate recall, and delayed recall were higher than those before treatment (<i>P</i><0.05); the HbA1c level was lower than that before treatment (<i>P</i><0.05). In the medium-temperature group, the total MoCA score and the scores of memory and delayed recall, attention, and language were higher than those before treatment (<i>P</i><0.05). STM accuracy was higher than before treatment (<i>P</i><0.05), and STM average reaction time was shorter than before treatment (<i>P</i><0.05) in both the high-temperature and medium-temperature groups. After treatment, the total MoCA score and the scores of visuospatial and executive function, memory and delayed recall, attention, and language in the high-temperature group were higher than those in the medium- and low-temperature groups (<i>P</i><0.05); MMSE score, STM accuracy, and ROCF immediate recall and delayed recall scores were higher than those in the medium- and low-temperature groups (<i>P</i><0.05); STM average reaction time was shorter than that in the medium- and low-temperature groups (<i>P</i><0.05); HbA1c level was lower than that in the low-temperature group (<i>P</i><0.05). The total MoCA score, attention score, and MMSE score in the medium-temperature group were higher than those in the low-temperature group (<i>P</i><0.05), and STM average reaction ti","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1233-1240"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国针灸Pub Date : 2025-09-12Epub Date: 2025-02-21DOI: 10.13703/j.0255-2930.20240911-k0001
Na Zhang, Youhong Xiong, Kejuan Ge, Yimei Liu
{"title":"[Clinical observation of <i>Jin</i>'s three-needle therapy combined with game therapy in the treatment of autism spectrum disorder].","authors":"Na Zhang, Youhong Xiong, Kejuan Ge, Yimei Liu","doi":"10.13703/j.0255-2930.20240911-k0001","DOIUrl":"10.13703/j.0255-2930.20240911-k0001","url":null,"abstract":"<p><strong>Objective: </strong>To observe the clinical effect of <i>Jin</i>'s three-needle therapy combined with game therapy on children with autism spectrum disorder (ASD).</p><p><strong>Methods: </strong>Sixty children with ASD were randomly divided into an observation group and a control group, with 30 cases in each. The children in the observation group received <i>Jin</i>'s three-needle therapy combined with game therapy. The acupoints used in <i>Jin</i>'s three-needle therapy included Zhisanzhen, Niesanzhen, Sishenzhen and Naosanzhen, and matches acupoints with syndromes. The acupoints included Shenting (GV24), Naohu (GV17) and bilateral Benshen (GB13), Naokong (GB19), Xinshu (BL15), Zusanli (ST36), etc. The needles were retained for 1 h for scalp acupuncture and not retained for body acupuncture. Game therapy included social interaction, music and dance, language stimulation, etc. The children in the control group were treated with the same game therapy in the observation group. Treatments were administered once daily, five times a week, with a three-month course considered as one treatment cycle, and a total of two cycles were provided. The scores of childhood autism rating scale (CARS), autism behavior scale (ABC) and 0-6-year-old Children's neuropsychological development assessment scale (children's psychological scale) were compared between the two groups before treatment and after 3 and 6 months of treatment.</p><p><strong>Results: </strong>After 3 and 6 months of treatment, the CARS and ABC scores of both groups were lower than those before treatment (<i>P</i><0.01). After 6 months of treatment, the CARS and ABC scores of the observation group were lower than those of the control group (<i>P</i><0.05). After 3 and 6 months of treatment, the scores of gross motor, fine motor, adaptive ability, language, and social behaviors in both groups were higher than those before treatment (<i>P</i><0.01). After 3 months of treatment, the observation group showed a greater improvement in gross motor, fine motor, adaptive ability, and social behaviors compared to the control group (<i>P</i><0.05). After 6 months of treatment, the observation group showed a greater improvement in gross motor, fine motor, adaptive ability, language, and social behaviors compared to the control group (<i>P</i><0.01, <i>P</i><0.05).</p><p><strong>Conclusion: </strong><i>Jin</i>'s three-needle therapy combined with game therapy is an effective method for the treatment of ASD, which shows more obvious advantages than simple game therapy in promoting the improvement of children's ability and reducing related behavior.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 9","pages":"1259-1264"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}