Acta Parasitologica最新文献

{"title":"First Molecular and Phylogenetic Identification of Toxoplasma Gondii in Sheep Liver Intended for Human Consumption in Northern Tunisia","authors":"Yosra Amdouni,&nbsp;Ines Hammami,&nbsp;Nadia Farhat,&nbsp;Mourad Rekik,&nbsp;Mohamed Gharbi","doi":"10.1007/s11686-024-00894-z","DOIUrl":"10.1007/s11686-024-00894-z","url":null,"abstract":"<p>The aim of this study was to estimate the molecular infection prevalence of <i>Toxoplasma gondii</i> in sheep liver tissues destined for human consumption. A total number of 224 liver tissues were collected from slaughtered sheep in Sejnane slaughterhouse (Northwest Tunisia). PCR was used to detect <i>T. gondii</i> DNA in liver tissues followed by phylogenetic analysis of amplicons. The phylogenetic tree was then constructed to compare the partial sequences of the ITS1 gene with GenBank sequences.</p><p>The overall molecular prevalence of <i>T</i>. <i>gondii</i> in sheep livers was 25% (56/224). The highest molecular prevalence of <i>T. gondii</i> was recorded in sheep aged of less than one year old (27.3%; 52/190). Infection prevalence was significantly higher in Noire de Thibar breed (33%; 17/51) compared to other breeds (<i>p</i> = 0.023). There were no differences depicted according to sheep’s gender. The <i>T. gondii</i> sequences obtained in the present study (GenBank accession numbers: OR509829 and OR509830) were 98.40–100% homologous to <i>T. gondii</i> sequences published in the GenBank. These results highlight a high level of <i>T. gondii</i> contamination of tissues destined for human consumption. Further studies are needed to improve our knowledge on different genotypes of <i>T. gondii</i> that infect Tunisian sheep population.</p>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1682 - 1689"},"PeriodicalIF":1.2,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three New Species of Sciadicleithrum (Monogenoidea, Dactylogyridae) Parasitizing Cichlid Fishes (Cichliformes: Cichlidae) in the Northeastern Peru","authors":"Germán Augusto Murrieta Morey,&nbsp;Hilmer A. Dávila,&nbsp;Mariana Vásquez Arimuya,&nbsp;Alana Lislea de Sousa,&nbsp;Celso L. Cruces,&nbsp;Jhon D. Chero","doi":"10.1007/s11686-024-00895-y","DOIUrl":"10.1007/s11686-024-00895-y","url":null,"abstract":"<div><h3>Introduction</h3><p>The present study describes three new dactylogyrid species infecting the gill filaments of cichlid fishes (Cichliformes: Cichlidae) from the Amazon basin, Peru: <i>Sciadicleithrum amazoniensis</i> n. sp. on <i>Biotodoma cupido</i> (Heckel, 1840), and <i>Sciadicleithrum feliciajaramae</i> n. sp. and <i>Sciadicleithrum souzatecci</i> n. sp. on <i>Bujurquina peregrinabunda</i> Kullander, 1986.</p><h3>Materials and methods</h3><p>Some monogeneans were stained with Gomori’s trichrome and mounted in Canada Balsam to determine internal soft structures. Others were cleared in Hoyer’s medium for the study of sclerotized structures. Drawings were made using a drawing tube and a microprojector.</p><h3>Results</h3><p><i>Sciadicleithrum amazoniensis</i> n. sp. is characterized by the presence of a male copulatory organ (MCO) with a coil of approximately 2 counterclockwise rings, an accessory piece articulated to base of the MCO with an expanded proximal end and a bifurcated distal end, and a sinistral vaginal aperture. <i>Sciadicleithrum feliciajaramae</i> n. sp. can be differentiated from all its congeners by its J-shaped MCO with about half a counterclockwise loop and a rod-shaped accessory piece articulated to the base of the MCO, with the distal end bent. <i>Sciadicleithrum souzatecci</i> n. sp. differs from all other members of <i>Sciadicleithrum</i> by having an elongated MCO with about a clockwise loop and a funnel-shaped base. Additionally, <i>Sciadicleithrum souzatecci</i> n. sp. is characterized by its weakly sclerotized, C-shaped accessory piece with a robust middle process.</p><h3>Conclusions</h3><p>Present findings are added to the other 26 species previously known in <i>Sciadicleithrum</i>.This is the first data on the parasites of <i>B</i>. <i>peregrinabunda</i>.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1674 - 1681"},"PeriodicalIF":1.2,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Averrhoa carambola Leaf Extract Induces Apoptosis-Like Death with Increased ROS Generation in Leishmania donovani","authors":"Priyanka Ghosh,&nbsp;Dibyapriya Roy Chowdhury,&nbsp;Pujayita Devgupta,&nbsp;Tapati Chakraborti","doi":"10.1007/s11686-024-00902-2","DOIUrl":"10.1007/s11686-024-00902-2","url":null,"abstract":"<div><h3>Purpose</h3><p>The parasitic disease leishmaniasis is responsible for high mortality and morbidity rates worldwide. The visceral form is the most severe form of leishmaniasis (or leishmaniosis), which is caused predominantly by <i>Leishmania donovani</i>. Currently, clinically recommended antileishmanial drugs are not convenient because of several medical complications and resistance issues. Phytocompounds are the best candidates in this regard. The present study aimed to evaluate the antileishmanial activity of <i>Averrhoa carambola</i> leaf extract.</p><h3>Methods</h3><p>The antipromastigote activity and cytotoxicity were assessed using the MTT assay. Morphological distortions were determined using phase contrast microscopy and scanning electron microscopy (SEM). Reactive oxygen species (ROS) production, nonprotein thiol depletion and apoptotic death in promastigotes were determined via flow cytometry. UV–visible spectroscopy and energy dispersive X-ray (EDX) spectroscopy was performed for elemental analysis. Fourier-transform infrared spectroscopy (FTIR) and liquid chromatography‒mass spectrometry (LCMS) were used to characterize the phytocomponent(s) present in the extract.</p><h3>Results</h3><p>The chloroform extract of <i>Averrhoa carambola</i> leaf (AC_CEX) (IC₅₀ = 50.76 ± 1.7 µg/mL) exhibited the highest activity, followed by the ethyl acetate, hexane, and methanol extracts. AC_CEX has also exhibited lower toxicity towards host macrophages. AC_CEX also induced morphological distortions in promastigotes, with significant generation of ROS and the concomitant apoptosis initiation followed by a decrease in the nonprotein thiol level. The major phytometabolites present in AC_CEX were identified from the National Institute of Standards and Technology (NIST) database and from a literature review.</p><h3>Conclusions</h3><p>This study suggested that <i>Averrhoa carambola</i> leaf extracts are rich in some classes of biologically active phytocompounds and exhibit good antileishmanial activity.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1501 - 1516"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11686-024-00902-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Blood Feeding Preference of Aedes aegypti (Diptera: Culicidae) when Offered Diabetic and Non-Diabetic Blood","authors":"Fatma Bursali","doi":"10.1007/s11686-024-00867-2","DOIUrl":"10.1007/s11686-024-00867-2","url":null,"abstract":"<div><h3>Purpose </h3><p><i>Aedes aegypti</i> (L.,1762) is a primary vector of arboviral infections like dengue, yellow fever, Zika. Female mosquitoes are influenced by various physical and chemical cues from host when blood feeding, e.g., they find some individuals with certain blood types or certain conditions more attractive than others. This study determined whether <i>Ae. aegypti</i> shows a preference when offered blood from a patient with diabetes mellitus (DM), an endocrine disorder associated with abnormal glucose metabolism, compared to healthy blood from non-DMs.</p><h3>Methods</h3><p>In the dual feeding experiments, forty newly emerged female mosquitoes were provided with two blood feeding systems with blood from a non-diabetic (healthy) and diabetic patient using artificial feeders. Blood from 12 diabetic and 12 non-diabetic patients was matched by ABO blood type (e.g., diabetic type O blood was compared with non-diabetic type O blood). The number of mosquitoes that landed and fed from each membrane was counted every 2 min for thirty minutes.</p><h3>Results</h3><p><i>Ae. aegypti</i> species significantly preferred for blood from non-diabetic individuals (50–65% among the different blood type groups) compared to blood from diabetic individuals. Using multiplex allele-specific PCR it was also determined that, <i>Ae. aegypti</i> significantly preferred the O blood group regardless of blood sugar level compared to others.</p><h3>Conclusion</h3><p><i>Ae. aegypti</i> has less preference for diabetic blood to non-diabetics. Regardless people affected with this condition need to take preventive measures to reduce mosquito bites as they tend to have weaker immune systems and can experience more severe cases of dengue.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1630 - 1639"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quadriacanthus (Monogenea, Dactylogyridae) from Catfishes in the Democratic Republic of the Congo: Description of a New Species from Heterobranchus longifilis (Teleostei, Clariidae)","authors":"Archimède Mushagalusa Mulega,&nbsp;Imane Rahmouni,&nbsp;Nikol Kmentová,&nbsp;Gyrhaiss Kapepula Kasembele,&nbsp;Pascal Mulungula Masilya,&nbsp;Abdelaziz Benhoussa,&nbsp;Maarten Van Steenberge,&nbsp;Maarten P. M. Vanhove","doi":"10.1007/s11686-024-00900-4","DOIUrl":"10.1007/s11686-024-00900-4","url":null,"abstract":"<div><h3>Purpose</h3><p>Studies on monogeneans parasitizing representatives of Siluriformes in Africa remain scarce and fragmentary. In order to contribute to fill this gap, we screened <i>Heterobranchus longifilis</i> from the Lindi River in the Democratic Republic of the Congo.</p><h3>Methods</h3><p><i>Heterobranchus longifilis</i> was purchased from fishermen in DR Congo, province of Tshopo, in Kisangani town, the Lindi River. The monogeneans were individually isolated from the gill and transferred directly onto a slide in a drop of Hoyer’s medium.</p><h3>Results</h3><p><i>Quadriacanthus lindiensis</i> n. sp. is morphologically similar to <i>Quadriacanthus longifilisi.</i> However, it is distinguished from the latter by its non-sclerotized vagina, its dorsal cunei shape and the size of its bars.</p><h3>Conclusion</h3><p>Only <i>Q. lindiensis</i> n. sp. was found on the gills of the single individual of <i>H. longifilis</i> screened. In the future, a representative sampling should enable us to verify if <i>Q. lindiensis</i> n. sp. co-occurs with other species known to parasitize <i>H. longifilis</i>.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1530 - 1537"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11686-024-00900-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Histopathological and Molecular Characterization of Giant Thorny-headed Worm, Macracanthorhynchus hirudinaceus (Pallas, 1781) (Acanthocephala: Oligacanthorhynchidae) in Wild Boars, Sus scrofa Linnaeus, 1758 from Eastern Türkiye","authors":"Figen Celik,&nbsp;Seyma Gunyakti Kilinc,&nbsp;Songul Ceribasi,&nbsp;Harun Kaya Kesik,&nbsp;Sami Simsek","doi":"10.1007/s11686-024-00873-4","DOIUrl":"10.1007/s11686-024-00873-4","url":null,"abstract":"<div><h3>Background</h3><p><i>Macracanthorhynchus hirudinaceus</i> (Pallas, 1781) is a zoonotic acanthocephalan that parasitizes the small intestine of wild boars. It is a pathogenic that causes economic losses, and poses a public health threat due to increased emergence.</p><h3>Purpose</h3><p>The aims of this study is describes histopathologically the damage caused by <i>M. hirudinaceus</i> in the small intestine of wild boar <i>Sus scrofa</i> Linnaeus, 1758, and molecularly characterize this parasite (sequences, haplotypes, phylogeny) for the first time in Elazig city, Türkiye.</p><h3>Results</h3><p>A high prevalence of infection was obtained. Upon separating the worms, it was discovered that there were ulcers resembling craters in the center, of the small intestine mucosa, surrounded by edema. The intestine wall where the parasite attached was damaged, with the villi epithelium and lamina propria in the mucosa being destroyed. The genomic DNA was isolated from all <i>M. hirudinaceus</i> samples, and PCR amplified the 489 bp gene fragments were sequenced and confirmed that all 21 sequences were <i>M. hirudinaceus</i>. The haplotype analysis of the sequences revealed the presence of a central star-shaped haplotype, in addition to four other haplotypes.</p><h3>Conclusion</h3><p>After conducting sequence analysis, the genetic differences between the <i>M. hirudinaceus</i> sequences obtained in this study and those reported from Europe and Japan suggest that this parasite is endemic to Türkiye’s local wild boar population. Also, four haplotypes were identified, distinguishing it from other haplotypes by 1–5 mutation steps. It is essential to consider the worm’s sequences and the formation of haplotypes, since these intrinsic characteristics may impact in the epidemiology and pathology of the worm in the future.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1640 - 1647"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Entamoeba histolytica in Different Water Sources of Niğde Province of Turkey","authors":"Cemal Candan,&nbsp;Mustafa Karatepe,&nbsp;Bilge Karatepe","doi":"10.1007/s11686-024-00886-z","DOIUrl":"10.1007/s11686-024-00886-z","url":null,"abstract":"<p>This study was carried out to determine the presence of <i>Entamoeba histolytica</i> in water sources of Niğde province in Turkey, between June and November 2021.</p><p>A total of 90 water samples were taken from 15 different water sources (drinking water, well water, spring water, wastewater and dam water) every month and the presence of <i>E. histolytica</i> antigens in the samples was examined by ELISA.</p><p>The positivity for <i>E. histolytica</i> was determined in 7 (7.7%) of 90 samples. While no antigens were found in any of the samples in June and September, <i>E. histolytica</i> was positive for three samples (20%) in July, one sample (6.6%) in August and October and two samples in November (13.3%). One of 24 dam samples (4.1%), 1 of 12 wastewater samples (8.3%), 1 of 12 well samples (8.3%), and 4 of 24 fountain samples (16.6%) that examined by ELISA were found positive. On the other hand, none of the examined 18 spring samples were positive. In addition, 4 (8.8%) of 45 samples that examined in summer and 3 (6.6%) of 45 samples that examined in autumn were detected positive by using ELISA. <i>Entamoeba histolytica</i> positivity in samples was statistically insignificant in terms of months, water resources and seasons (<i>P</i> &gt; 0.05).</p><p>As a result, the presence of <i>E. histolytica</i>, which is an important public health problem in water sources, was determined for the first time in Niğde province of Türkiye with this study.</p>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1517 - 1521"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Elimination Status of Visceral Leishmaniasis in Southeast Asia Region","authors":"Samiur Rahim,&nbsp;Muhammad Manjurul Karim","doi":"10.1007/s11686-024-00880-5","DOIUrl":"10.1007/s11686-024-00880-5","url":null,"abstract":"<div><h3>Purpose</h3><p>Visceral leishmaniasis (VL) is caused by an intracellular parasite that is transmitted to humans by sandfly bites. It is prevalent throughout Asia, Africa, the Americas, and the Mediterranean area, where 147 million people are at risk of contracting the illness. The manifestation of heterotrophic illness relies on both <i>Leishmania</i> implicated and the host’s immunological response, ranging from asymptomatic to severe leishmaniasis with potentially lethal effects.</p><h3>Method</h3><p>We reviewed the literature (published till 31st December 2023) on the worldwide situation of leishmaniasis, standard and novel detection techniques, and traditional and modern treatment strategies and endeavors to eliminate VL. Moreover, epidemiological data was collected from the World Health Organization’s publicly available databases. GraphPad Prism Version 8 was used to analyze and produce figures based on the epidemiological data.</p><h3>Results</h3><p>Diagnosis of parasites in tissues or serology is commonly employed. Diagnosis by identifying parasite DNA using molecular techniques is becoming more popular. Despite recent findings of <i>L. donovani</i> resistance to pentavalent antimoniate medications, it continues to be the cornerstone in the medical management of VL. Amphotericin B and its lipid formulations, injectable paromomycin, and oral miltefosine are among the new therapy options being researched. The number of reported VL cases has reduced remarkably over the last decade due to human interventions made to eliminate VL. Particularly countries from the South East Asian region have experienced momentous progress in reducing VL cases and eliminating this disease from this region. Owing to the robust elimination programs, countries such as Bangladesh has eliminated VL as a public health concern. India and Nepal are on the verge of its elimination.</p><h3>Conclusion</h3><p>Rapid diagnosis, effective and inexpensive treatment, simple access to newly discovered medications, appropriate vector control, and a well-designed vaccine are all required for the elimination of this disease burden in impoverished areas of the globe.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1704 - 1716"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metazoan Endoparasites of the Gecko Phyllopezus periosus (Squamata: Phyllodactylidae) Inhabiting the Rock Cliffs of a Waterfall Canyon in the Semi-Arid Region from Northeastern Brazil","authors":"José Guilherme Gonçalves-Sousa,&nbsp;Charles de Sousa Silva,&nbsp;Samuel Cardozo Ribeiro,&nbsp;Herivelto Faustino Oliveira,&nbsp;Robson Waldemar Ávila","doi":"10.1007/s11686-024-00868-1","DOIUrl":"10.1007/s11686-024-00868-1","url":null,"abstract":"<div><h3>Purpose</h3><p>This study describes the composition and infection patterns of macro endoparasites associated with the lizard <i>Phyllopezus periosus.</i></p><h3>Methods</h3><p>We collected 115 <i>P. periosus</i> over 12 expeditions on the rocky cliffs of the Missão Velha waterfall canyon in northeastern Brazil. Specimens were collected by hand, during active searches conducted between 18:00 h and 23:30 h. The infection patterns were estimated using prevalence, total abundance, and mean intensity of infection for all parasites found.</p><h3>Results</h3><p>A total of 4256 parasites were collected from 104 hosts, resulting in an exceptionally high overall prevalence of 90.4%. No significant ontogenetic difference in the prevalence of infection was detected. Although juveniles exhibited a high parasite prevalence their parasite loads were significantly lower compared to adults. Six species of endoparasites were found; among these, the nematode <i>Spauligodon oxkutzcabiensis</i> was the most common endoparasite in the digestive tract, while the pentastomid <i>Raillietiella mottae</i> was the only species found in the respiratory tract.</p><h3>Conclusions</h3><p>Infection rates in Gekkota species appear to correlate with body size, with larger individuals generally exhibiting a higher prevalence. This pattern was also observed across separate populations of <i>P. periosus</i> and other geckos from distinct ecological domains. The dominance of the monoxenous <i>S. oxkutzcabiensis</i> highlights potential transmission mechanisms, suggesting that behaviors such as limb licking after feeding may contribute to its prevalence. The occurrence of <i>Physalopteroides venancioi</i>,<i> Oswaldocruzia</i> sp., <i>Parapharyngodon</i> sp., <i>Physaloptera</i> sp., infecting <i>P. periosus</i> are new records for this host. These findings significantly contribute to the knowledge of host-parasite dynamics in geckos.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1587 - 1591"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11686-024-00868-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sero-Prevalence of Visceral Leishmaniasis and Associated Risk Factors among Febrile Patients Attending Metema Hospital, West Gondar Zone, North West Ethiopia","authors":"Solomon Tesfaye,&nbsp;Tibebnesh Getu,&nbsp;Tilahun Yohannes,&nbsp;Damtew Bekele","doi":"10.1007/s11686-024-00882-3","DOIUrl":"10.1007/s11686-024-00882-3","url":null,"abstract":"<div><h3>Introduction</h3><p>In Ethiopia, visceral leishmaniasis (VL) is a public health concern that has been spreading to new endemic foci in recent years. An estimated 3.2 million people are at risk of infection, with 3700–7400 new cases yearly. Thus, the study aimed to determine the prevalence of VL and associated risk factors among febrile patients attending Metema Hospital, North West Ethiopia.</p><h3>Methods</h3><p>A hospital-based cross-sectional study was conducted on 404 febrile patients attending Metema Hospital from February 2021 to June 2021. The test for VL was done using an immune-chromatographic test (RK39) according to the manufacturer’s instructions (InBios International Inc., USA). An interviewer-administered, pretested questionnaire was used to collect data on risk factors associated with VL. Logistic regression and Chi-square assessed the association between VL and the associated risk factors.</p><h3>Reults</h3><p>The overall prevalence of visceral leishmaniasis was 18.8% (76/404), with a higher prevalence of VL in males, in the age category between 21 and 30, in study participants who completed elementary school, and in those who earned less than 500 birr monthly compared to their counterparts. Houses with thatched roofs (adjusted odd ratio (AOR) = 17.648, 95CI = 6.549,47.563), houses with mud walls (AOR = 2.538, 95% CI = 1.187–5.411), cattle ownership (AOR = 3.173, 95% CI = 1.286–7.826), dog ownership (AOR = 2,533, 95% CI = 1.256–5.111), presence of <i>Acacia</i> trees near houses (AOR = 1.975, 95% CI:1.004–3.886), presence of <i>Balanites</i> tree (AOR = 3.015, 95% CI = 1.610–5.992), and outdoor sleeping (AOR = 2.259, 95% CI: 1.107–14.607) were the predictors of VL in the present study.</p><h3>Conclusions</h3><p>In the study area, VL is still very common. Thus, preventing and controlling infection in the area is largely dependent on raising community awareness of VL prevention and control measures and implementing the necessary interventions on the determinants that have been identified.</p></div>","PeriodicalId":6932,"journal":{"name":"Acta Parasitologica","volume":"69 3","pages":"1621 - 1629"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}