Acta Ophthalmologica最新文献

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Choroidal vascular hyperpermeability patterns in central serous chorioretinopathy correlate with microperimetry: CERTAIN study report 4. 中央浆液性脉络膜视网膜病变的脉络膜血管高渗透性模式与显微视野检查相关:CERTAIN研究报告4。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-09-17 DOI: 10.1111/aos.17588
Jennifer M Chang-Wolf, Laurenz J B Pauleikhoff, Chabelie Ruiters, Annette C Moll, Reinier O Schlingemann, Elon H C van Dijk, Roselie M H Diederen, Camiel J F Boon
{"title":"Choroidal vascular hyperpermeability patterns in central serous chorioretinopathy correlate with microperimetry: CERTAIN study report 4.","authors":"Jennifer M Chang-Wolf, Laurenz J B Pauleikhoff, Chabelie Ruiters, Annette C Moll, Reinier O Schlingemann, Elon H C van Dijk, Roselie M H Diederen, Camiel J F Boon","doi":"10.1111/aos.17588","DOIUrl":"https://doi.org/10.1111/aos.17588","url":null,"abstract":"<p><strong>Purpose: </strong>This report evaluates the association of three distinct leakage patterns of choroidal vascular hyperpermeability (CVH) on indocyanine green angiography (ICGA), previously correlated with disease chronicity, with retinal sensitivity measured by microperimetry in central serous chorioretinopathy (CSC): unifocal indistinct signs of hyperpermeability (uni-FISH), multifocal (multi-FISH), and diffuse (DISH).</p><p><strong>Methods: </strong>The CERTAIN study is a retrospective analysis of consecutive CSC patients referred to a tertiary centre between 01/09/2021 and 30/11/2022. Patients underwent ultra-widefield (UWF) and 55° ICGA plus comprehensive multimodal imaging, including microperimetry. Two independent graders assessed CVH patterns on UWF and 55° ICGA. In case of disagreement, a third grader adjudicated. Eyes with CVH and mesopic microperimetry data were included.</p><p><strong>Results: </strong>In total, 154 eyes from 91 CSC patients were included. On UWF ICGA, DISH showed lower macular sensitivity than the uni-FISH reference (-2.61 dB, p = 0.047). Sensitivity was also lower (-2.24 dB, p = 0.03) when comparing DISH to a combined uni- and multi-FISH group (FISH). On 55° ICGA, DISH again showed lower sensitivity versus uni-FISH (-3.13 dB, p = 0.01) and the FISH group (-2.82 dB, p = 0.010).</p><p><strong>Conclusions: </strong>The CVH patterns of uni-FISH, multi-FISH, and DISH demonstrate a marked association with levels of retinal sensitivity in CSC patients, particularly macular sensitivity, which is lower in DISH compared to (uni-)FISH. Our findings highlight the potential role of ICGA patterns in assessing disease severity and functional prognostication.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Customizing AI-based screening with real-world data: Practical insights from diabetic retinopathy. 使用真实世界数据定制基于人工智能的筛查:来自糖尿病视网膜病变的实用见解。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-09-11 DOI: 10.1111/aos.17591
Broder Poschkamp, Liane Kantz, Petra Augstein, Allam Tayar, Lars Kaderali, Martin Busch, Beathe Bohl, Sebastian Paul, Lisa Lüdtke, Marie-Christine Bründer, Daniel Schulz, Hanna Grabow, Elke Gens Dipl, Antonia Müller, Emily Martin, Wolfgang Kerner, Jörg Reindel, Andreas Stahl
{"title":"Customizing AI-based screening with real-world data: Practical insights from diabetic retinopathy.","authors":"Broder Poschkamp, Liane Kantz, Petra Augstein, Allam Tayar, Lars Kaderali, Martin Busch, Beathe Bohl, Sebastian Paul, Lisa Lüdtke, Marie-Christine Bründer, Daniel Schulz, Hanna Grabow, Elke Gens Dipl, Antonia Müller, Emily Martin, Wolfgang Kerner, Jörg Reindel, Andreas Stahl","doi":"10.1111/aos.17591","DOIUrl":"https://doi.org/10.1111/aos.17591","url":null,"abstract":"<p><strong>Purpose: </strong>Diabetic retinopathy (DR) is a leading cause of vision loss in middle-aged adults globally. Although artificial intelligence (AI)-based screening tools like IDx-DR (classification) and Thirona RetCAD (regression) have shown high sensitivity in controlled settings, real-world screening faces challenges due to missing or low-quality images and inadequate adaptation to local healthcare needs. The objective was to compare the performance of two AI-based DR screening algorithms (IDx-DR and RetCAD) that analyse non-mydriatic images, against ophthalmologists' mydriatic fundoscopy with image analysis and the impact of customized referral threshold modification ('Greifswald modification') on screening outcomes.</p><p><strong>Methods: </strong>This one-centre observational study included 1716 patients with diabetes mellitus (Clinical Trials Register: DRKS00035967). Sensitivity, specificity, the proportion of ungradable images and the reduction in ophthalmologic evaluations were assessed. Customized referral threshold modification was conducted using the Youden Index.</p><p><strong>Results: </strong>In 98 patients (5.7%), no images could be acquired, and 35 patients (2.1%) had incomplete image sets for IDx-DR. IDx-DR rejected 438 patients (25.5%) due to image quality, while RetCAD flagged 134 eyes from 120 patients (6.9%) but provided output for all. Among analysable images, sensitivities ranged from 70.4% (RetCAD) to 93.6% (RetCAD with Greifswald modification). Including all patients reduced sensitivity from 52.7% (IDx-DR) to 79.9% (RetCAD with Greifswald modification). AI screening reduced ophthalmologic exam needs by 47.5% to 78.5%.</p><p><strong>Conclusions: </strong>Real-world DR screening performance of AI algorithms, when including non-analysable patients, can be substantially lower than in controlled studies. The use of regression algorithms enabled the customization of referral thresholds, improving screening accuracy and reducing the clinical burden.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology and burden of mild/moderate versus high myopia in Germany: A claims data analysis. 德国轻度/中度与高度近视的流行病学和负担:一项索赔数据分析。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-09-08 DOI: 10.1111/aos.17589
Tarcyane Barata Garcia, Nils Kossack, Marc Pignot, Mohammed Dagher, Alexander K Schuster, Kun Shi-van Wielink
{"title":"Epidemiology and burden of mild/moderate versus high myopia in Germany: A claims data analysis.","authors":"Tarcyane Barata Garcia, Nils Kossack, Marc Pignot, Mohammed Dagher, Alexander K Schuster, Kun Shi-van Wielink","doi":"10.1111/aos.17589","DOIUrl":"https://doi.org/10.1111/aos.17589","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the prevalence, healthcare resource utilization (HCRU) and associated costs of myopia in Germany, comparing mild/moderate and high myopia across various age groups using real-world data.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted using data from the WIG2 benchmark database. Patients with a diagnosis of myopia (ICD-10-GM H52.1) were categorized into mild/moderate or high myopia. The study population was stratified into preschool (0-5 years), primary school (6-9 years), secondary school (10-17 years), adult (18-59 years), elderly (60-75 years) and very old (>75 years) age groups. Prevalence trends were evaluated across paediatric and adolescent subpopulations. Propensity score matching was applied to balance group differences. HCRU and associated costs were analysed for each cohort.</p><p><strong>Results: </strong>Between 2018 and 2022, mild/moderate myopia consistently exhibited higher prevalence across all age groups compared to high myopia. Prevalence of both myopia types increased significantly with age, particularly in females, with mild/moderate myopia reaching 19.86% (95% CI 19.08-20.66) at age 17, compared to 14.00% (95% CI 13.37-14.67) in males. In 2022, individuals with high myopia had significantly higher ophthalmic HCRU and associated costs compared to those with mild/moderate myopia. The economic burden was notably higher in older age groups, with increased hospitalizations and outpatient visits. High myopia incurred higher costs across all age groups, with the largest difference in the very old cohort (€234.20).</p><p><strong>Conclusion: </strong>This study highlights the significant clinical and economic burden of high myopia in Germany. Targeted interventions are needed to manage myopia progression and reduce healthcare costs, particularly in ageing individuals.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-world outcomes of aflibercept 8 mg in patients previously treated for neovascular age-related macular degeneration. 阿非利赛普8mg治疗新生血管性老年性黄斑变性患者的实际疗效。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-09-08 DOI: 10.1111/aos.17590
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund
{"title":"Real-world outcomes of aflibercept 8 mg in patients previously treated for neovascular age-related macular degeneration.","authors":"Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund","doi":"10.1111/aos.17590","DOIUrl":"https://doi.org/10.1111/aos.17590","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age-related macular degeneration (nAMD).</p><p><strong>Methods: </strong>This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti-VEGF therapies at Sahlgrenska University Hospital between February 2024 and February 2025. Data on best-corrected visual acuity (BCVA), central retinal thickness (CRT), pigment epithelial detachment (PED) height, fluid status, treatment intervals, time to fluid recurrence and adverse events were collected.</p><p><strong>Results: </strong>181 eyes (167 patients; mean age 80.4 ± 8.5 years; 67.7% female) were included, with a median follow-up of 12.9 weeks (range 4.1-48.1). A total of 415 injections were administered (mean 2.1 ± 1.5 per eye). BCVA remained stable (baseline 0.46 ± 0.31 logMAR; post-treatment 0.47 ± 0.37 logMAR; p = 0.18). CRT decreased significantly (-19.5 ± 47.2 μm; p < 0.001), as did PED height (-37.4 ± 68.4 μm; p < 0.001). Intraretinal fluid prevalence decreased from 34.3% to 19.3% (p < 0.001) and subretinal fluid from 53.0% to 33.7% (p < 0.001). The median maximal dry interval achieved was nine weeks, and analysis of interval extension showed a statistically significant mean increase of 1.27 ± 4.24 weeks overall (p = 0.0009), particularly in eyes dry at baseline. The median time to fluid recurrence among those with reactivation was ten weeks. Higher baseline CRT predicted greater CRT reduction (-44.1 μm per 100 μm increase; p < 0.001) but shorter dry intervals. Safety was favourable, with one case (0.6% per eye; 0.2% per injection) of mild anterior uveitis and no cases of intraocular pressure elevation.</p><p><strong>Conclusions: </strong>Switching to aflibercept 8 mg led to stable vision, significant anatomical improvements, extended treatment intervals and a favourable short-term safety profile. Longer follow-up is warranted.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital aniridia: European COST action ANIRIDIA-NET guidelines for diagnosis, management and care. 先天性无虹膜:欧洲成本行动无虹膜网诊断,管理和护理指南。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-09-02 DOI: 10.1111/aos.17587
Davide Romano, Vito Romano, Alejandra Daruich, Giulio Ferrari, Matthieu Robert, Francesco Semeraro, Neil Lagali, Dominique Bremond-Gignac
{"title":"Congenital aniridia: European COST action ANIRIDIA-NET guidelines for diagnosis, management and care.","authors":"Davide Romano, Vito Romano, Alejandra Daruich, Giulio Ferrari, Matthieu Robert, Francesco Semeraro, Neil Lagali, Dominique Bremond-Gignac","doi":"10.1111/aos.17587","DOIUrl":"https://doi.org/10.1111/aos.17587","url":null,"abstract":"<p><p>Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated with the disease, such as cataract, keratopathy and optic nerve hypoplasia. Mutation in the PAX6 gene is the most common cause of congenital aniridia, but other causative mutations exist. The main ocular symptoms experienced by those with congenital aniridia are photophobia, glare, low visual acuity, dryness/irritation of the ocular surface and nystagmus. Management and follow-up of patients with congenital aniridia can be challenging due to the lack of effective therapeutic options and the complexity of ocular manifestations and outcomes. These guidelines for the diagnosis, management and care of congenital aniridia have been developed at the European level, thanks to ANIRIDIA-NET, based on a review of the scientific literature on clinical and molecular characterization, therapeutic options as well as non-medical approaches.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A model for de novo pigmentation of amelanotic retinal pigment epithelial cells. 无色素变性视网膜色素上皮细胞新生色素沉着模型。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-09-02 DOI: 10.1111/aos.17572
Santosh Gupta, Lyubomyr Lytvynchuk, Taras Ardan, Hana Studenovska, Georgina Faura, Lars Eide, Ljubo Znaor, Slaven Erceg, Knut Stieger, Jan Motlik, Goran Petrovski
{"title":"A model for de novo pigmentation of amelanotic retinal pigment epithelial cells.","authors":"Santosh Gupta, Lyubomyr Lytvynchuk, Taras Ardan, Hana Studenovska, Georgina Faura, Lars Eide, Ljubo Znaor, Slaven Erceg, Knut Stieger, Jan Motlik, Goran Petrovski","doi":"10.1111/aos.17572","DOIUrl":"https://doi.org/10.1111/aos.17572","url":null,"abstract":"<p><strong>Purpose: </strong>Retinal Pigment Epithelial (RPE) cells perform critical functions in the visual cycle. Their melanin pigmentation, which is organized into specialized compartments - melanosomes, is highly critical for proper vision. A chemical method to induce pigmentation in a non-pigmented model of ARPE-19 cells was applied using L-DOPA as a repurposed drug from the current treatment of Parkinson's disease.</p><p><strong>Methods: </strong>L-DOPA was optimized for its toxic effect on ARPE-19 cells along with pigmentation development. Gene expression and immunocytochemistry confirmed upregulation of melanogenesis-related genes and proteins. Melanosomes were characterized by TEM.</p><p><strong>Results: </strong>We found 1000 μM L-DOPA to induce pigmentation of ARPE-19 cells by Day 3, and achieve full pigmentation by Day 5. By Day 5, L-DOPA at 1000 μM induced mitochondrial and nuclear DNA damage. However, the gene expression of RPE-specific markers (tyrosinase, TYRP1, CRALBP, PEDF) was significantly different in L-DOPA-treated ARPE-19 cells compared to non-treated ones. Positive expression for Tyrosinase enzyme was confirmed by ICC on both Day 3 and Day 5 of L-DOPA treatment. Transmission electron microscopy showed the de novo melanosome formation with ultrastructural features of various stages of maturity (Stage I to IV), apical-basal polarity and melanosome localization on the apical side of the L-DOPA-treated ARPE-19 cells.</p><p><strong>Conclusion: </strong>Our study showed that L-DOPA treatment could induce de novo melanosome formation in amelanotic RPEs. We propose a newer approach of developing an ex vivo model for de novo pigmentation of RPE cells with cell-specific modification and culture condition optimization.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nationwide trends in macular hole, epiretinal membrane and floaters surgery, 2010-2023. 2010-2023年全国黄斑孔、视网膜前膜和飞蚊手术趋势。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-09-01 DOI: 10.1111/aos.17585
Birgitte Romme Nielsen, Martin Nissen Hermann, Jakob Grauslund, Morten la Cour, Mark Alberti
{"title":"Nationwide trends in macular hole, epiretinal membrane and floaters surgery, 2010-2023.","authors":"Birgitte Romme Nielsen, Martin Nissen Hermann, Jakob Grauslund, Morten la Cour, Mark Alberti","doi":"10.1111/aos.17585","DOIUrl":"https://doi.org/10.1111/aos.17585","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the incidence of pars plana vitrectomy (PPV) for full-thickness macular hole (FTMH), epiretinal membrane (ERM) and floaters over time and across regions in Denmark.</p><p><strong>Methods: </strong>This nationwide registry-based study included all patients undergoing PPV for FTMH, ERM, or floaters in Denmark from 2010 to 2023. Crude and age-standardized incidence rates were calculated using Poisson regression, stratified by sex, age, region and year.</p><p><strong>Results: </strong>Among 11 693 patients undergoing PPV, the median age was 71 years (IQR, 66-76) and 83% (9744/11 693) were pseudophakic at surgery. Overall incidence rates per 100 000 person-years were 5.7 (95% CI, 5.5-5.8) for FTMH, 7.1 (6.9-7.2) for ERM, and 1.8 (1.7-1.9) for floaters. FTMH surgery was more common in females across all ages, while ERM and floater surgeries were more frequent in males aged ≥60 years. From 2010-2012 to 2021-2023, the incidence increased for FTMH and ERM, while floater surgery declined in females and remained stable in males. Regional variation was observed for all indications, most notably for ERM.</p><p><strong>Conclusion: </strong>The incidence of PPV for both FTMH and ERM rose significantly from 2010 to 2023. The regional variation in FTMH may indicate undertreatment, while differences in ERM and floater surgeries reflect the absence of standardized guidelines for ERM and floater surgery, underscoring the need for national guidelines to ensure equitable ophthalmic care.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of angle kappa and multifocal intraocular lenses and their effect on visual outcomes. 角度kappa和多焦人工晶状体及其对视力的影响。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-08-30 DOI: 10.1111/aos.17561
Thomas Kohnen, Viswanathan Ramasubramanian, Rajaraman Suryakumar
{"title":"A review of angle kappa and multifocal intraocular lenses and their effect on visual outcomes.","authors":"Thomas Kohnen, Viswanathan Ramasubramanian, Rajaraman Suryakumar","doi":"10.1111/aos.17561","DOIUrl":"https://doi.org/10.1111/aos.17561","url":null,"abstract":"<p><p>Although most patients are satisfied with their vision after multifocal intraocular lens (IOL) implantation, dissatisfaction has been reported for various reasons, including poor visual outcomes and visual disturbances. Many published reports hypothesise that preoperative angle kappa may be an associated factor in patient dissatisfaction. Therefore, there is considerable interest in understanding the connection between preoperative angle kappa and visual outcome after multifocal IOL implantation. This narrative review presents clinical data on angle kappa and its relationship to visual outcomes, visual quality, IOL position and visual disturbances after cataract surgery and multifocal IOL implantation. Although recent advances improved objective measurement of angle kappa, inconsistencies in reporting angle kappa make comparison across studies and patient populations difficult. The consensus among multiple studies was that angle kappa did not influence visual and refractive outcomes following multifocal IOL surgery. However, there were conflicting reports on the correlation between angle kappa and subjective visual quality and patient-reported visual disturbances. Differences in study design, patient characteristics and multifocal IOL characteristics may explain these discrepancies. IOL orientation, tilt and decentration may be affected by angle kappa and likely contribute to some visual disturbances. Additional modelling studies using multifocal IOLs and ocular biometry could improve our understanding of the relationship between angle kappa and IOL alignment. Accurate assessment of preoperative angle kappa in patients with cataracts is important for successful outcomes and patient satisfaction.</p>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The state of your journal: Acta Ophthalmologica in 2024. 你的期刊现状:2024年《眼科学报》。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-08-27 DOI: 10.1111/aos.17584
Kai Kaarniranta, Einar Stefánsson
{"title":"The state of your journal: Acta Ophthalmologica in 2024.","authors":"Kai Kaarniranta, Einar Stefánsson","doi":"10.1111/aos.17584","DOIUrl":"https://doi.org/10.1111/aos.17584","url":null,"abstract":"","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Threat to fixation and vision-related quality of life in patients with open-angle glaucoma. 对开角型青光眼患者固定及视力相关生活质量的威胁。
IF 2.8 3区 医学
Acta Ophthalmologica Pub Date : 2025-08-26 DOI: 10.1111/aos.17586
Charlotte Almer, Dorothea Peters
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