Acta medica Indonesiana最新文献_第3页

Early Enteral Feeding Versus Total Parenteral Feeding After Surgery in Severe Acute Pancreatitis: An Evidence-Based Case Report. 重症急性胰腺炎术后早期肠内喂养与全肠外喂养：一项基于证据的病例报告。

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Acta medica Indonesiana Pub Date : 2025-04-01

Roy Akur Pandapotan, Anissa Syafitri, Andre Setiawan, Burhan Gunawan, Nathalia Gracia Citra, Josephine Alicia Bierhuijs, Johana Titus

{"title":"Early Enteral Feeding Versus Total Parenteral Feeding After Surgery in Severe Acute Pancreatitis: An Evidence-Based Case Report.","authors":"Roy Akur Pandapotan, Anissa Syafitri, Andre Setiawan, Burhan Gunawan, Nathalia Gracia Citra, Josephine Alicia Bierhuijs, Johana Titus","doi":"","DOIUrl":"","url":null,"abstract":"Background: Acute pancreatitis is a self-limiting inflammatory disease that in some cases may lead to severe acute pancreatitis. To prevent this development, multimodal management, including nutritional management, is used in treating acute pancreatitis patients. The controversy between parenteral and enteral feeding has led to major debate. This case report aims to assess which method has better outcomes based on multiple cases of organ failure, inflammatory response, and length of hospital stay.Methods: A 46-year-old male presented to the Emergency Department of our hospital with acute abdominal pain, nausea, and vomiting, 12 h before admission. Based on physical and further examination, the patient was diagnosed with severe acute pancreatitis and underwent a necrotomy procedure. Articles from multiple databases were obtained and assessed using the Cochrane Collaboration Risk of Bias tool. The articles were analyzed using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and a forest plot model. Effect size quantification for continuous and categorical variables was analyzed using continuous and binary random effect models, respectively.Results: Seven articles were obtained after exclusion and review. A total of 491 patients with acute/severe acute pancreatitis were assessed. These seven articles conclude that enteral nutrition has advantages over parenteral nutrition.Conclusion: Our study concluded that early enteral feeding provides better clinical improvement, reduced lipase enzyme levels, and shortened length of hospital stay.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"275-283"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Ramadan Fasting on Malondialdehyde, Poly (ADP-Ribose) Polymerase, Sirtuin 1, Nuclear Receptor Subfamily 1 Group D Member 1, and Transforming Growth Factor Beta in Chronic Kidney Disease: A Prospective Cohort Study. 斋月禁食对慢性肾病患者丙二醛、聚（adp -核糖）聚合酶、Sirtuin 1、核受体亚家族1组D成员1和转化生长因子β的影响：一项前瞻性队列研究

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Acta medica Indonesiana Pub Date : 2025-04-01

Drajad Priyono, Eti Yerizel, Harnavi Harun, Netti Suharti

{"title":"Effect of Ramadan Fasting on Malondialdehyde, Poly (ADP-Ribose) Polymerase, Sirtuin 1, Nuclear Receptor Subfamily 1 Group D Member 1, and Transforming Growth Factor Beta in Chronic Kidney Disease: A Prospective Cohort Study.","authors":"Drajad Priyono, Eti Yerizel, Harnavi Harun, Netti Suharti","doi":"","DOIUrl":"","url":null,"abstract":"Background: Chronic kidney disease (CKD) is a global health problem with increasing prevalence. This study aims to analyze the effect of Ramadan fasting on important biomarkers in CKD patients.Methods: A prospective cohort study was conducted on 30 CKD patients with stages 1, 2, and 3A who underwent Ramadan fasting. Measurements of MDA, PARP, SIRT1, NR1D1, and TGF-β levels were carried out before fasting, 2 weeks during fasting, and after fasting using the Enzyme-linked immunosorbent assay (ELISA) method.Results: There were significant decreases in urea, fasting blood glucose, HbA1C, and uric acid levels (p<0.05). MDA and SIRT1 decreased significantly (p<0.001), while PARP and NR1D1 increased significantly (p<0.001). TGF-β also showed a decrease. There were no significant changes in lipid profiles, creatinine, and albumin.Conclusion: Ramadan fasting has significant effects on several biochemical parameters and biological markers in early-stage CKD patients. These changes indicate potential improvements in oxidative stress, cell autophagy, inflammation regulation, and circadian rhythm. Further studies are needed to evaluate the long-term effects and clinical implications of these findings in CKD management.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"228-236"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report. 粘粒蛋白自身抗体在寻常型天疱疮诊断中的作用1例。

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Acta medica Indonesiana Pub Date : 2025-04-01

Diane Lukito Setiawan, Munawaroh Fitriah, Awalia Awalia

引用次数: 0

Successful Ultrasound-Guided Dry Needling for Treatment of Piriformis Syndrome. 超声引导干针成功治疗梨状肌综合征。

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Acta medica Indonesiana Pub Date : 2025-04-01

Guntur Darmawan, Anwar Samhari Bin Mat Arshad, Suryo Anggoro Kusumo Wibowo

{"title":"Successful Ultrasound-Guided Dry Needling for Treatment of Piriformis Syndrome.","authors":"Guntur Darmawan, Anwar Samhari Bin Mat Arshad, Suryo Anggoro Kusumo Wibowo","doi":"","DOIUrl":"","url":null,"abstract":"Piriformis syndrome is an often overlooked cause of chronic buttock or low back pain, sometimes radiating to the posterior thigh. Despite various treatment options, a definitive standard therapy has not been established. Dry needling has recently gained attention as a non-pharmacological intervention, especially when guided by ultrasound to enhance accuracy and safety. A 69-year-old woman presented with a 9-month history of fluctuating right gluteal pain, aggravated by prolonged sitting and movements. Physical examination revealed tenderness in the piriformis area and positive provocative tests, with no neurological deficits. After failure of previous pharmacological and physiotherapeutic interventions, the patient underwent ultrasound-guided dry needling of the piriformis muscle. The procedure was performed using an in-plane technique with a 0.3 x 75 mm needle and elicited a twitch response. After two sessions, the patient reported a significant reduction in pain intensity from 7/10 to 2/10. Ultrasound-guided dry needling offers several benefits, including precise targeting of the piriformis muscle, avoidance of chemical agents, and reduced risk of adverse effects. The analgesic effect is attributed to inactivation of myofascial trigger points and neuromodulation involving reduced levels of substance P and calcitonin gene-related peptide. We conclude that ultrasound-guided dry needling appears to be a safe, effective, and minimally invasive option in the management of piriformis syndrome, particularly when conventional therapies fail.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"273-274"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Gastric Acid Suppression Therapy in Erosive Esophagitis: From H2 Receptor Antagonists, Proton Pump Inhibitors, to Potassium-Competitive Acid Blockers. 胃酸抑制治疗在糜烂性食管炎中的作用：从H2受体拮抗剂、质子泵抑制剂到钾竞争性酸阻滞剂。

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Acta medica Indonesiana Pub Date : 2025-04-01

Ryan Herardi, Ari Fahrial Syam, Achmad Fauzi, Ikhwan Rinaldi, Sharon Sandra, Anisya Zakiyyahaya Arvant

{"title":"Role of Gastric Acid Suppression Therapy in Erosive Esophagitis: From H2 Receptor Antagonists, Proton Pump Inhibitors, to Potassium-Competitive Acid Blockers.","authors":"Ryan Herardi, Ari Fahrial Syam, Achmad Fauzi, Ikhwan Rinaldi, Sharon Sandra, Anisya Zakiyyahaya Arvant","doi":"","DOIUrl":"","url":null,"abstract":"Erosive esophagitis (EE) is an inflammation of the esophageal mucosa resulting from gastric and duodenal acid reflux, affecting approximately 55% of gastroesophageal reflux disease (GERD) patients in Indonesia. Effective acid suppression is essential for mucosal healing and symptomatic relief. Histamine-2 receptor antagonist (H2RA) was initially used for standard treatment for GERD, including EE, reducing gastric acid secretion by blocking H2 receptors. However, their efficacy is limited by inadequate acid suppression. Proton pump inhibitors (PPIs) became the mainstay therapy due to their stronger and longer-lasting acid suppression. Although PPIs have been proven to be quite effective, they have several limitations, including slow onset and inability to provide sustained acid suppression over a full 24-hour period. In recent years, Potassium-competitive acid blockers (PCAB) have become known as a category of drugs that effectively suppress gastric acid production, through a slightly different mechanism, and have advantages over PPIs, including faster onset and longer time of action. Both PPIs and PCABs can be used as therapy for patients with EE. PCABs are more recommended, especially in patients with severe grades of EE. H2RAs may still be considered in patients who have already received PPI therapy but continue to experience unresolved nocturnal acid symptoms.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"284-292"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subphenotypic Classification of Immune Response in Sepsis: Predicting Mortality and Guiding Future Personalized Immunotherapy. 脓毒症免疫反应的亚表型分类：预测死亡率和指导未来的个性化免疫治疗。

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Acta medica Indonesiana Pub Date : 2025-04-01

Velma Herwanto, Khie Chen Lie, Robert Sinto, Leonard Nainggolan

{"title":"Subphenotypic Classification of Immune Response in Sepsis: Predicting Mortality and Guiding Future Personalized Immunotherapy.","authors":"Velma Herwanto, Khie Chen Lie, Robert Sinto, Leonard Nainggolan","doi":"","DOIUrl":"","url":null,"abstract":"The most recent definition of sepsis highlights the dysregulation of the host's immune response to infection, which varies between individual hosts, with patients predominantly presenting with either hyperinflammation, immunoparalysis, or a combination of both states. Therefore, management strategies must be tailored to accommodate the heterogeneity of patients with sepsis, as these conditions are associated with distinct prognoses and therapeutic approaches. Identification of the immune response in patients with sepsis can be achieved through advanced techniques, such as gene expression profiling or, more simply, through a subphenotypic approach. This article introduces a subphenotypic classification of the sepsis immune response into macrophage activation-like syndrome (MALS), where pathological macrophage activation leads to excessive hyperinflammation, immunoparalysis, or neither. Patients are classified using serum ferritin levels and monocyte HLA-DR expression, which is assessed using peripheral blood. This classification demonstrates significant differences in survival across groups, which is attributed to their distinct underlying biological processes. Immunotherapeutic options also differ for these three groups. In the future, such immune response classifications will be valuable in sepsis management algorithms for personalized prognostication and therapy.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"264-272"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wernicke Encephalopathy Associated with Crohn's Disease. 与克罗恩病相关的韦尼克脑病

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Acta medica Indonesiana Pub Date : 2025-04-01

Marco Vidor, Wirdasari Wirdasari, Virly Nanda Muzellina, Simon Salim

{"title":"Wernicke Encephalopathy Associated with Crohn's Disease.","authors":"Marco Vidor, Wirdasari Wirdasari, Virly Nanda Muzellina, Simon Salim","doi":"","DOIUrl":"","url":null,"abstract":"Poorly controlled Crohn's disease is associated with several complications, including malabsorption of vitamins and minerals such as vitamin D, vitamin B12, and vitamin B1 (thiamine). Thiamine, among other vitamins, plays a crucial role in Adenosine Triphosphate formation as well as nerve propagation. Thiamine deficiency initially manifests as wet or dry beriberi but may lead to the devastating Wernicke-Korsakoff syndrome. In this report, we present a case of full-blown Wernicke encephalopathy associated with uncontrolled Crohn's disease. An 18-year-old young man was admitted with a chief complaint of hematemesis for 2 weeks before admission. He was previously diagnosed with Crohn's disease in the past year, with constipation as the predominant symptom, and has been taking mesalazine 500 mg twice daily. Esophagogastroduodenoscopy and colonoscopy re-evaluation showed a worsening picture of Crohn's disease pangastritis. The patient experienced swelling in both legs, the scrotum, and the upper extremities during hospital admission. On day 14 of hospitalization, the patient fell into a state of confusion with visual and auditory hallucinations, ophthalmoplegia, and ataxia. A Brain MRI showed a typical picture of Wernicke encephalopathy. Intravenous thiamine was administered, and the patient regained consciousness. His clinical symptoms improved every day until he was discharged. Uncontrolled Crohn's disease may have several complications that clinicians need to be aware of, including thiamine deficiency. Wernicke encephalopathy shows a devastating clinical picture, but with thiamine therapy, it may resolve before further deterioration leads to irreversible Korsakoff syndrome.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"251-256"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic Performance of INA-FRAIL and Study of Osteoporotic Fractures (SOF) Index Compared to Cardiovascular Health Study (CHS) in Diagnosing Frailty Syndrome in Older Adults with Heart Failure. ina -脆弱的诊断性能及骨质疏松性骨折（SOF）指数与心血管健康研究（CHS）在老年心力衰竭虚弱综合征诊断中的比较研究

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Acta medica Indonesiana Pub Date : 2025-04-01

Eka Ginanjar, Aulia Rizka, Aulia Malik Ayub, Ikhwan Rinaldi, Rino Alvani Gani, Cosphiadi Irawan, Noto Dwimartutie

{"title":"Diagnostic Performance of INA-FRAIL and Study of Osteoporotic Fractures (SOF) Index Compared to Cardiovascular Health Study (CHS) in Diagnosing Frailty Syndrome in Older Adults with Heart Failure.","authors":"Eka Ginanjar, Aulia Rizka, Aulia Malik Ayub, Ikhwan Rinaldi, Rino Alvani Gani, Cosphiadi Irawan, Noto Dwimartutie","doi":"","DOIUrl":"","url":null,"abstract":"Background: There is currently no gold standard for assessing frailty syndrome in older adults with heart failure. The Cardiovascular Health Study (CHS) is a reference standard for evaluating frailty in older adults with heart failure. Still, it requires a dynamometer and a spacious space, rendering it impractical in daily practice. The INA-FRAIL and Study of Osteoporotic Fractures (SOF) Index can often be easy to use; however, it has not been evaluated for diagnostic performance on older adults with heart failure in Indonesia. This study aimed to assess the diagnostic performance of INA-FRAIL and SOF-Index in diagnosing frailty in older adults with heart failure.Methods: This cross-sectional study evaluated the diagnostic performances of INA-FRAIL and SOF-Index compared to CHS as the gold standard in this study. The population was heart failure patients aged > 60 at Cipto Mangunkusumo Hospital.Results: Analysis from 81 samples shows the prevalence of frailty based on CHS (35.5%), INA-FRAIL (23.5%), and SOF-Index (8,6%). Diagnostic performance analysis of INA-FRAIL showed a sensitivity of 55,17% (95% CI 35.69-73.55), specificity 94.23% (95% CI 84.05- 98.79), and AUC 0.805 (95% CI 0.698-0.912). Diagnostic performance analysis of SOF showed 20,69% sensitivity (95% CI 7.99 - 39.72), 98.08% specificity (95% CI 89.74 - 99.95), and AUC 0.719 (95% CI 0.595 - 0.843).Conclusion: INA-FRAIL and SOF-Index had a significant association with CHS. The cut-off point of INA-FRAIL ≥1 showed the highest sensitivity, while INA-FRAIL ≥2 showed the highest Youden index. The cut-off point of SOF ≥1 showed the highest sensitivity and the highest Youden index.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"200-211"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A 28-Year-Old Woman with Impending Thyroid Storm, Hyperbilirubinemia, and Total Atrioventricular Block. 28岁女性甲状腺风暴、高胆红素血症和房室传导阻滞。

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Acta medica Indonesiana Pub Date : 2025-04-01

K Heri Nugroho Hario Seno, Hesti Triwahyu Hutami, Friska Anggraini Helena Silitonga, Risa Ardiani

{"title":"A 28-Year-Old Woman with Impending Thyroid Storm, Hyperbilirubinemia, and Total Atrioventricular Block.","authors":"K Heri Nugroho Hario Seno, Hesti Triwahyu Hutami, Friska Anggraini Helena Silitonga, Risa Ardiani","doi":"","DOIUrl":"","url":null,"abstract":"Thyrotoxicosis, a state of excess thyroid hormone, often presents with diverse clinical manifestations, including thyroid storm, a rare but critical condition. Here, we present a case of a 28-year-old woman with thyrotoxicosis, hyperbilirubinemia, and total atrioventricular (AV) block. The patient exhibited jaundice, chest discomfort, and a history of chronic diarrhea, weight loss, tremors, and exertional dyspnea. She was on propylthiouracil and propranolol for two weeks. Physical examination revealed jaundice, proptosis, a large goiter, and tremors. Laboratory tests on admission indicated elevated liver enzymes, hypokalemia, and markedly elevated thyroid hormones. ECG revealed total AV block. Treatment involved hydrocortisone, thiamazole, discontinuation of propranolol, and gradual correction of electrolyte imbalances. The patient improved clinically, and propranolol's discontinuation improved the rhythm disturbance. The Patient was discharged for outpatient Graves' disease management. Future assessments may include an electrophysiology study if needed. Total AV block in thyrotoxicosis is rare. This case highlights the complexity of managing thyrotoxicosis with concurrent hepatic and cardiac complications, emphasizing the importance of tailored treatment strategies and close monitoring.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"241-245"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144606986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of Short Chain Fatty Acid (SCFA) Levels with Transient Elastography Values and Controlled Attenuation Parameters in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD). 非酒精性脂肪性肝病（NAFLD）患者短链脂肪酸（SCFA）水平与瞬时弹性成像值和控制衰减参数的相关性

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Acta medica Indonesiana Pub Date : 2025-04-01

Desi Astari, Chyntia Olivia Maurine Jasirwan, Cosmas Rinaldi Adithya Lesmana, Marcellus Simadibrata, Juferdy Kurniawan, Evy Yunihastuti, Kuntjoro Harimurti, Pringgodigdo Nugroho

{"title":"Correlation of Short Chain Fatty Acid (SCFA) Levels with Transient Elastography Values and Controlled Attenuation Parameters in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD).","authors":"Desi Astari, Chyntia Olivia Maurine Jasirwan, Cosmas Rinaldi Adithya Lesmana, Marcellus Simadibrata, Juferdy Kurniawan, Evy Yunihastuti, Kuntjoro Harimurti, Pringgodigdo Nugroho","doi":"","DOIUrl":"","url":null,"abstract":"Background: The current hypothesis regarding the mechanism of Non-Alcoholic Fatty Liver Disease (NAFLD) is the multiple hit theory, where one of the factors involved is gut microbiota. Short-chain fatty acid (SCFA) is the main metabolite of gut microbiota and is suspected to play a role in the development of NAFLD. This study aims to determine the correlation between SCFA levels (acetate, propionate, butyrate) and the degree of fibrosis and steatosis in patients with NAFLD assessed by controlled attenuation parameter (CAP) and transient elastography (TE).Methods: A cross-sectional study that included 33 consecutively selected patients at Cipto Mangunkusumo Hospital was conducted from January to August 2023. Fecal sample collection was performed for SCFA examination using GC-MS (Gas Chromatography-Mass Spectrometry). Absolute fecal SCFAs were analyzed for correlation with steatosis and fibrosis based on controlled attenuation parameter (CAP) and transient elastography (TE) values.Results: Subjects were predominantly female (51.5%), with an average age of 49 years, an average CAP value of 296 dB/m, and a median transient elastography value of 6.1 kPa. The ratio of acetate, propionate, and butyrate values in the subjects was 59:24:17. A moderate negative correlation was observed between the absolute butyrate and CAP values (r=-0.522; p=0.002).Conclusion: There is no correlation was identified between short-chain fatty acid levels and transient elastography values.","PeriodicalId":6889,"journal":{"name":"Acta medica Indonesiana","volume":"57 2","pages":"167-174"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144606989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0