Acta Oto-LaryngologicaPub Date : 2026-08-01Epub Date: 2026-05-04DOI: 10.1080/00016489.2026.2656280
Bingtong Lin, Junlin Fang, Genquan Huang, Xuyou Zhou, Danyang Meng, Juan Qu, Junjie Xu, Baoxiang Wang, Jin Hu
{"title":"Correlation between residual dizziness after repositioning of benign paroxysmal positional vertigo and motion sickness: an observational study.","authors":"Bingtong Lin, Junlin Fang, Genquan Huang, Xuyou Zhou, Danyang Meng, Juan Qu, Junjie Xu, Baoxiang Wang, Jin Hu","doi":"10.1080/00016489.2026.2656280","DOIUrl":"10.1080/00016489.2026.2656280","url":null,"abstract":"<p><strong>Background: </strong>During the onset of benign paroxysmal positional vertigo (BPPV), patients with motion sickness may experience more severe vestibular symptoms, which may affect the occurrence of residual dizziness (RD).</p><p><strong>Objectives: </strong>To study the correlation between RD after BPPV and motion sickness.</p><p><strong>Materials and methods: </strong>According to the history of motion sickness, the clinical characteristics of BPPV combined with motion sickness were analyzed. According to whether there was RD after successful repositioning, the patients were divided into RD group and non-RD group. The differences between the two groups were analyzed first, and then the influencing factors of RD were analyzed.</p><p><strong>Results: </strong>① The proportion of women, dizziness handicap inventory (DHI) score, Hamilton Anxiety Scale (HAMA) score and incidence of RD in the motion sickness group were higher than those in the non-motion sickness group. ② The age, course of diseases, history of BPPV, history of motion sickness, DHI score and HAMA score in the RD group were higher than those in the non-RD group. ③ History of motion sickness, age, course of disease, history of BPPV, DHI, and HAMA were the influencing factors of RD.</p><p><strong>Conclusions: </strong>Motion sickness is associated with RD, and may serve as a clinical indicator for risk stratification.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"997-1003"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147809581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2026-08-01Epub Date: 2026-04-24DOI: 10.1080/00016489.2026.2658632
Felat Toprak, Ayça Arslan, Bayram Barış Büyük, Emine Benzer, Nazan Bozdoğan
{"title":"The effect of tumor budding index on clinical parameters in early-stage oral cavity cancers.","authors":"Felat Toprak, Ayça Arslan, Bayram Barış Büyük, Emine Benzer, Nazan Bozdoğan","doi":"10.1080/00016489.2026.2658632","DOIUrl":"10.1080/00016489.2026.2658632","url":null,"abstract":"<p><strong>Background: </strong>Tumor budding is an established prognostic marker in colorectal cancer however, it is not routinely incorporated into risk assessment in oral cavity squamous cell carcinoma.</p><p><strong>Aims: </strong>To evaluate the impact of tumor budding on survival outcomes and lymph node metastasis in patients with oral cavity cancer undergoing surgical treatment.</p><p><strong>Material and methods: </strong>Between January 1, 2010 and January 1, 2021, 87 patients diagnosed with oral cavity cancer and who underwent surgery at our clinic were included in the study. Clinically T<sub>1-2</sub> was observed in 60 patients (69%), T<sub>3-4</sub> in 27 patients (31%), and neck dissection was not performed in 8 patients with T<sub>1</sub>N<sub>0</sub>M<sub>0</sub> due to comorbidities.</p><p><strong>Results: </strong>The most common site was the tongue in 61 cases (70.1%), followed by the buccal mucosa in 15 cases (17.2%). The median follow-up period was 46.5 months (0.3-160.9). Tumor budding was identified as an independent predictor of overall survival, disease-free survival, and lymph node metastasis in early-stage oral cavity squamous cell carcinoma.</p><p><strong>Conclusion: </strong>The presence of budding was associated with an increased risk of lymph node metastasis and shorter overall and disease-free survival.</p><p><strong>Significance: </strong>Routine assessment of tumor budding may contribute to postoperative risk classification and follow-up planning, beyond staging parameters.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1013-1018"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic endonasal surgery and radiotherapy in skull base chordomas: a 20-year retrospective analysis of long-term outcomes and prognostic factors.","authors":"Hongbing Li, Pengfei Guan, Huankang Zhang, Jimin Zhang, Ruiyue Liu, Dehui Wang, Weidong Zhao","doi":"10.1080/00016489.2026.2659351","DOIUrl":"10.1080/00016489.2026.2659351","url":null,"abstract":"<p><strong>Background: </strong>For skull base chordomas, two key aspects remain controversial: (1) the necessity of adjuvant RT following gross total resection (GTR) and (2) the comparative long-term efficacy of different RT modalities.</p><p><strong>Objective: </strong>This study aimed to evaluate the effects of endonasal endoscopic surgery, RT, and other variables on progression-free survival (PFS) and overall survival (OS) in patients with skull base chordomas.</p><p><strong>Method: </strong>A retrospective analysis was conducted on 83 patients (2006-2025) treated at the Affiliated Eye Ear Nose and Throat Hospital, Fudan University, to assess the prognosis of skull base chordoma between 2006 and 2025.</p><p><strong>Results: </strong>Between 2006 and 2014, GTR was achieved in 25.8% of patients. Between 2015 and 2022, GTR was achieved in 50.0% of patients. Multivariate Cox regression analysis revealed several independent prognostic factors. For PFS, GTR, the presence of complications, and a tumor volume <25 cm<sup>3</sup> were significantly associated with outcome. For OS, the independent predictors included STR, GTR and complications.</p><p><strong>Conclusions: </strong>Surgery remains the primary treatment for skull base chordoma. We therefore recommend pursuing maximal safe resection to achieve GTR whenever feasible. The efficacy of resection is also influenced by the endoscopic endonasal surgery learning curve. Our analysis also revealed tumor volume, and a complicated surgical course as independent prognostic factors. Furthermore, our data may not support the routine use of adjuvant RT following GTR.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1027-1036"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2026-08-01Epub Date: 2026-04-19DOI: 10.1080/00016489.2026.2659356
Rui Yang, Hui Li, Maoli Duan, Ling Lu
{"title":"Endoscopic myringoplasty of chronic suppurative otitis media: comparison in patients with dry ears to ones with wet ears.","authors":"Rui Yang, Hui Li, Maoli Duan, Ling Lu","doi":"10.1080/00016489.2026.2659356","DOIUrl":"10.1080/00016489.2026.2659356","url":null,"abstract":"<p><strong>Background: </strong>Chronic suppurative otitis media (CSOM) is characterized by recurrent otorrhea and tympanic membrane perforation. The selection of surgical technique and suitable time for myringoplasty remain variable and unclear.</p><p><strong>Objectives: </strong>This study aimed to compare the feasibility and effectiveness of the CSOM patients with dry and wet ears using endoscopic inlay and underlay myringoplasty.</p><p><strong>Methods: </strong>Sixty-four patients with CSOM who underwent endoscopic underlay or inlay myringoplasty were studied retrospectively. Cartilage-perichondrium grafts were used to repair tympanic membrane perforations. Pure-tone audiometry was performed at pre- and post-operation assessing hearing outcomes.</p><p><strong>Results: </strong>Successful closure of performed tympanic membrane with operations was achieved in all patients. Hearing improvement was observed in both the dry ear group and the wet ear group, with no statistically significant difference between the two groups (<i>p</i> > 0.05). Furthermore, there was no statistically significant difference in hearing improvement in the two groups by inlay and underlay technique. However, the operative time in wet ear group was statistically significant shorter in inlay myringoplasty group than in the underlay myringoplasty group (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>The closure rates of tympanic membrane perforation and post-operative hearing improvement were not affected in the wet ears. Endoscopic inlay myringoplasty might be a suitable option for patients with wet ears, offering shorter operative times, minimal trauma to middle ear structures.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1037-1043"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina Youssef, Christian Salameh, Souheil Hallit, Charlie Hanna
{"title":"Postoperative complications in children with clinically diagnosed sleep-disordered breathing undergoing tonsillectomy.","authors":"Christina Youssef, Christian Salameh, Souheil Hallit, Charlie Hanna","doi":"10.1080/00016489.2026.2705488","DOIUrl":"https://doi.org/10.1080/00016489.2026.2705488","url":null,"abstract":"<p><strong>Background: </strong>Children with clinically diagnosed sleep-disordered breathing (SDB)are at higher risk of respiratory complications following tonsillectomy. Decision to admit for surveillance post-operatively depends on variable patient-related factors. Further studies to find additional considerations can help refine the decision-making process, ultimately improving patient safety.</p><p><strong>Aims/objectives: </strong>To compare the rate of post-operative respiratory complications (PoRCs) between different surgical techniques and methods in children with clinically diagnosed SDB undergoing tonsillectomy.</p><p><strong>Material and methods: </strong>A retrospective study was conducted, including 139 children aged 6 months to 18 years who underwent tonsillectomy between January 2021 and June 2024 at three hospitals in Lebanon. Patients were compared according to postoperative respiratory complication status: 45 patients with PoRCs and 94 without PoRCs.</p><p><strong>Results: </strong>Undergoing the cautery method compared to coblation, undergoing total vs partial tonsillectomy, and higher ventilation rate had a significant association with higher odds of PoRCs.</p><p><strong>Conclusions and significance: </strong>In children with clinically diagnosed SDB undergoing tonsillectomy, the surgical technique, method, and airway management were significantly associated with the rate of PoRCs. Adequate choice of technique and method may be associated with reduced PoRCs in children with clinically diagnosed SDB undergoing tonsil surgery. These findings can assist clinicians in making informed decisions regarding post-operative care to reduce risks and improve clinical outcomes.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-10"},"PeriodicalIF":1.3,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148617868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral hearing levels in Meniere's disease may fluctuate simultaneously.","authors":"Yoshihiro Nitta, Hideaki Naganuma","doi":"10.1080/00016489.2026.2703418","DOIUrl":"https://doi.org/10.1080/00016489.2026.2703418","url":null,"abstract":"<p><strong>Background: </strong>We observe fluctuations in hearing thresholds in both ears of patients with unilateral Meniere's disease (MD), even during early stages. If hearing fluctuations on both sides are synchronized, this may be related to the pathophysiology of MD.</p><p><strong>Objectives: </strong>To examine whether hearing fluctuations in the affected and non-affected ears occur synchronously in patients with MD.</p><p><strong>Methods: </strong>We retrospectively analyzed 2985 pure-tone audiometry tests performed in 217 patients with definite MD. Based on pure-tone audiometry test results, we calculated average thresholds for low-, middle-, and high-tone hearing ranges and the differences between them on one audiometry test and that in the next test. When the affected side improved or diminished by ≥10 dB at two or more frequencies, we examined whether the non-affected side showed corresponding changes in each range.</p><p><strong>Results: </strong>Hearing fluctuations in the affected ear were significantly associated with simultaneous changes in the non-affected ear across all frequency ranges (<i>p</i> < 0.01). Changes occurred in the same direction, whereas no change in the affected ear corresponded to no change in the non-affected ear.</p><p><strong>Conclusions and significance: </strong>Hearing fluctuations in MD may occur synchronously in affected and non-affected ears, suggesting systemic or central involvement and the need for monitoring.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148629128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tinnitus outcomes after unilateral and bilateral cochlear implantation.","authors":"Masatoshi Hasegawa, Tadao Yoshida, Masumi Kobayashi, Daisuke Hara, Michihiko Sone","doi":"10.1080/00016489.2026.2699324","DOIUrl":"https://doi.org/10.1080/00016489.2026.2699324","url":null,"abstract":"<p><strong>Background: </strong>The effect of cochlear implantation (CI) on tinnitus, particularly unilateral versus bilateral implantation, remains unclear.</p><p><strong>Aims: </strong>To evaluate the effect of CI on tinnitus by comparing unilateral and bilateral implantation using tinnitus scores and objective hearing performance data.</p><p><strong>Materials and methods: </strong>This retrospective observational study was conducted at a single tertiary center in Japan. Sixty-one patients with hearing loss underwent unilateral or bilateral CI and preoperative and postoperative tinnitus evaluations. Tinnitus was measured using the tinnitus handicap inventory (THI) and Visual Analog Scale (VAS).</p><p><strong>Results: </strong>Of 61 patients, 10 with THI scores of 0 both preoperatively and postoperatively were excluded from the tinnitus change analysis; none developed new-onset tinnitus. Among the remaining 51, 36 had preoperative THI scores ≥7; 32 showed clinically meaningful improvement and four showed no change. Of 15 with THI scores <7, 14 showed no change and one showed worsening. No significant differences were found for THI or loudness, whereas the improvement group showed significantly longer daily device use time for distress (<i>p</i> < 0.05). Listening-environment exposure did not differ consistently between groups.</p><p><strong>Conclusions: </strong>In the tinnitus change analysis, tinnitus improved significantly after CI, but neither bilateral implantation nor longer daily device use demonstrated a clear exposure-response relationship with tinnitus reduction.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-10"},"PeriodicalIF":1.3,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148629177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maham Parveen, Sebastian Paul Lund Clark, Armin Azari Jafari, Frederik Severin Gråe Harbo, Pia Iben Pietersen
{"title":"Retrospective study of vestibular schwannoma in patients referred to MRI: prevalence and referral criteria.","authors":"Maham Parveen, Sebastian Paul Lund Clark, Armin Azari Jafari, Frederik Severin Gråe Harbo, Pia Iben Pietersen","doi":"10.1080/00016489.2026.2701321","DOIUrl":"https://doi.org/10.1080/00016489.2026.2701321","url":null,"abstract":"<p><strong>Background: </strong>Vestibular schwannoma (VS) is a rare, benign tumor of the vestibulocochlear nerve. Diagnosis relies on MRI, but nonspecific clinical symptoms make early identification challenging.</p><p><strong>Objective: </strong>To evaluate the prevalence of VS among MRI referrals and assess the clinical symptoms and referral criteria leading to imaging.</p><p><strong>Material and methods: </strong>This retrospective observational study was conducted at a tertiary university hospital from July 2023 to August 2024. Data were extracted from institutional radiological imaging archive system. The total number of MRI referrals, confirmed VS cases, and associated clinical symptoms were recorded. Referral patterns were analysed using the European Academy of Otology and Neuro-Otology (EAONO) criteria.</p><p><strong>Results: </strong>Of 600 MRI scans analyzed, 11 cases (1.8%) confirmed VS. Referrals were primarily made by private ENT specialists (68.5%). Tumor sizes ranged from 6-23 mm, with two tumors exceeding 20 mm, requiring consideration for surgery. Asymmetrical hearing loss was the most frequently mentioned symptom (80.8%), but no single symptom or combination reliably predicted VS.</p><p><strong>Conclusion: </strong>VS was an uncommon finding among MRI referrals. Asymmetric hearing loss was the predominant symptom but did not reliably predict tumor presence. The findings highlight the need to refine referral criteria to improve diagnostic efficiency and reduce unnecessary imaging.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148583302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}