小儿颈深部感染的临床特征和预后因素:一项回顾性研究。

IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY
Zehra Betül Paksoy, Melih Cayonu, Ali Demir
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引用次数: 0

摘要

背景:儿童深颈脓肿(PDNAs)是罕见的,但可引起严重的并发症。尽管在诊断和抗生素治疗方面取得了进展,但有效的PDNA管理仍然具有挑战性,需要及时诊断和靶向治疗。目的:本研究评估儿童pnas患者的临床特征、治疗方法和影响住院时间的因素。分析实验室标志物(血红蛋白、白蛋白、炎症指标)和脓肿特征与临床结果的关系。方法:对2019-2024年安卡拉比尔肯市医院72例PDNA病例进行回顾性分析。分析临床表现、实验室检查结果(血红蛋白、白蛋白)、脓肿大小和炎症指数(SII、NLR、SIRI)。结果:平均年龄6.69岁,6岁以下占51.38%。最常见的是喉周脓肿(40.3%),其次是咽后脓肿。抗生素治疗在33.3%的病例中成功,而66.7%的病例需要手术引流。延长住院时间与低血红蛋白(p = 0.003)和白蛋白(p = 0.034)、较大脓肿大小(p = 0.047)和炎症标志物升高(SIRI: p = 0.034)相关。007, SII: p = 0.015)。结论和意义:预后因素如血红蛋白、白蛋白和炎症指数在PDNA治疗中是必不可少的。手术干预在严重病例中起着关键作用,强调了标准化方案的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Features and prognostic factors in pediatric deep neck infections: a retrospective study.

Background: Pediatric deep neck abscesses (PDNAs) are uncommon but can cause serious complications. Despite advances in diagnostics and antibiotic therapies, effective PDNA management remains challenging, necessitating prompt diagnosis and targeted treatment.

Objectives: This study evaluated the clinical characteristics, treatment approaches, and factors affecting hospital stay in pediatric patients with PDNAs. Associations between laboratory markers (hemoglobin, albumin, inflammatory indices) and abscess characteristics with clinical outcomes were analyzed.

Methods: A retrospective review of 72 PDNA cases at Ankara Bilkent City Hospital (2019-2024) was performed. Clinical presentation, laboratory findings (hemoglobin, albumin), abscess size, and inflammatory indices (SII, NLR, SIRI) were analyzed.

Results: The mean age was 6.69 years, with 51.38% under six. Peritonsillar abscesses were the most common (40.3%), followed by retropharyngeal abscesses. Antibiotic therapy alone was successful in 33.3% of cases, while 66.7% required surgical drainage. Prolonged hospitalization was associated with low hemoglobin (p = .003) and albumin (p = .034), larger abscess size (p = .047), and elevated inflammatory markers (SIRI: p = .007, SII: p = .015).

Conclusions and significance: Prognostic factors such as hemoglobin, albumin, and inflammatory indices is essential in PDNA management. Surgical intervention plays a key role in severe cases, emphasizing the need for standardized protocols.

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来源期刊
Acta Oto-Laryngologica
Acta Oto-Laryngologica 医学-耳鼻喉科学
CiteScore
2.50
自引率
0.00%
发文量
99
审稿时长
3-6 weeks
期刊介绍: Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.
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