{"title":"Forward-looking Intravascular Ultrasound Catheter with an Electromagnetic Micro-Motor","authors":"Yunfei Li, Hu Tang, Siping Chen, Jue Peng","doi":"10.1109/ULTSYM.2019.8925894","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925894","url":null,"abstract":"Current commercial side-looking intravascular ultrasound catheter utilizes long flexible shaft to rotate the transducer for intravascular imaging. However, due to the characteristic of the side-looking intravascular ultrasound catheter, it cannot be used for imaging of chronic total occlusion. Furthermore, using an external motor to drive the transducer will cause non-uniform imaging distortion. An effective way to solve these problems is directly driving a forward-looking transducer to work by using a distal micro-motor. In this study, a catheter consists of an electromagnetic motor and a high-frequency forward-looking transducer was developed. The ionic liquid was used as the wire to connect the transducer and the ground. The prototype of catheter that fabricated in this study has a 2 mm outer diameter, and the motor has a maximal speed of the 275 PRS.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"40 1","pages":"1805-1807"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81409844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Side Lobe Estimation Accuracy Using Side Lobe Free Image","authors":"M. Jeong, S. Kwon, M. Choi","doi":"10.1109/ULTSYM.2019.8925550","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925550","url":null,"abstract":"In order to effectively suppress side lobes in ultrasound imaging, it is necessary to quantify the signal amplitude due to side lobes at imaging points. The received channel data before receive beamforming are modeled as a sum of sinusoids having different spatial frequencies depending on the angle incident on a receiving array. In the signal constituting the channel data, the signal due to the main lobe has a DC frequency, whereas the signal due to the side lobe has a spatial frequency that is approximately proportional to the incident angle. Taking the Fourier transform of the received channel data after zero padding, we can accurately estimate side lobes. In computer simulation of ultrasound images, we generate ultrasonic echoes returned from random scatterers. Because we already know the position of all reflectors, we can separate the signals reflected due to the main and side lobes so that the true side lobe level at each imaging point can be computed accurately. The main lobe image can be used as a gold standard for assessing a side lobe suppression filter. The true and estimated side lobes can be used in side lobe suppression filtering of ultrasound images. We obtained the conventional, true side lobe, and estimated side lobe images for an object containing a wire and a cyst using computer simulation in a 64 channel focusing system with a 5 MHz linear array transducer. In the hypoechoic cyst, the estimated side lobe is almost the same as the true side lobe. We confirmed that the estimated side lobe can effectively be used in side lobe suppression filtering. Therefore, it is feasible to quantitatively estimate side lobes from the channel data, and improve the performance of the side lobe suppression filter in ultrasound imaging.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"43 1","pages":"1451-1454"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82546381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yayu Hao, Qin Wang, Yi Yang, Zhi Liu, Qiong He, Lai Wei, Jianwen Luo
{"title":"Non-rigid Motion Correction for Ultrasound Localization Microscopy of the Liver in vivo","authors":"Yayu Hao, Qin Wang, Yi Yang, Zhi Liu, Qiong He, Lai Wei, Jianwen Luo","doi":"10.1109/ULTSYM.2019.8925749","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925749","url":null,"abstract":"Chronic liver diseases (CLDs) are a major killer of humans, and more than 1 billion people suffer from CLDs worldwide, which are likely to develop significant liver fibrosis (LF) and even cirrhosis. However, current noninvasive diagnostic methods for liver diseases are insensitive to early lesions, so accurate assessment of LF at early stage is very important for the treatment arrangement and fibrosis reversal before cirrhosis. Ultrasound localization microscopy (ULM) with contrast microbubbles (MBs) have been proposed by several groups and may have potential in evaluating LF at early stage. Unfortunately, breathing and heart beating can introduce motion artifacts in liver ULM, which brings the challenge for LF evaluation with ULM. Recently, rigid motion correction (MoCo) has been proposed to improve the performance of ULM of the brain and kidney. Considering typical non-rigid motion in the liver, the performance of rigid MoCo may be limited. Therefore, we propose a non-rigid MoCo method based on speckle tracking to improve the performance of liver ULM more effectively. Results of in vivo experiments indicate that ULM with non-rigid MoCo obtains better resolution and more continuous microvessels (MVs) than rigid MoCo.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"53 1","pages":"2263-2266"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78653702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonic structural health monitoring - current applications and potential","authors":"P. Cawley","doi":"10.1109/ULTSYM.2019.8926176","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8926176","url":null,"abstract":"The trend to the application of structural health monitoring (SHM) as an alternative to periodic nondestructive evaluation (NDE) is discussed and examples are referenced of the use of both ultrasonic guided waves and bulk waves. Dealing with the volumes of data generated to produce useful information is a significant issue and fruitful areas for future research are given.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"1 1","pages":"2107-2109"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78975566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanical Characterization of Biofilms by Optical Coherence Elastography (OCE) Measurements of Elastic Waves","authors":"Hong-Cin Liou, F. Sabba, G. Wells, O. Balogun","doi":"10.1109/ULTSYM.2019.8925714","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925714","url":null,"abstract":"Biofilms are biological materials composed of microbial communities encased in a self-produced extracellular polymeric substance (EPS). The viscoelastic properties of biofilms are related to the cross-link density in the EPS and ultimately the cohesiveness of biofilms. Accurate measurement of biofilm viscoelastic properties at the mesoscale remains a challenge. Rheological measurements, although being more common, provide only global properties, do not permit in-situ characterization, and are not amenable to complex sample geometries. To address these challenges, our work seeks to develop a nondestructive framework for characterizing biofilm viscoelastic properties using elastic wave propagation measured by the optical coherence elastography technique. The framework holds great potential to elucidate spatially varying mechanical properties and their correlation with sample morphology and composition.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"27 1","pages":"2194-2197"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87949768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Ghis, Matthieu Matringe, O. Ndjoye-Kogou, F. Blard, F. Frassati, L. Van-Jodin
{"title":"High Density Arrays of Carbon Nanomembrane Ultrasonic MEMS","authors":"A. Ghis, Matthieu Matringe, O. Ndjoye-Kogou, F. Blard, F. Frassati, L. Van-Jodin","doi":"10.1109/ULTSYM.2019.8925677","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925677","url":null,"abstract":"Ultrathin carbon membranes are proposed for implementation as vibrating part for ultrasonic transducers. The mechanical properties of these membranes allow a significant operation in forced oscillations mode. Unlike resonant systems, the frequency range of operation is very wide, and the design of the transducers more flexible. Dense arrays of small size transducers are suitable to phased array techniques. The first test devices were manufactured and characterized; the feasibility of emitting and receiving acoustic waves with such devices has been demonstrated.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"44 1","pages":"2148-2152"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86853964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ge Zhang, P. Weinberg, C. Dunsby, M. Tang, S. Harput, M. Toulemonde, Jacob Broughton-Venner, Jiaqi Zhu, K. Riemer, K. Christensen-Jeffries, Jemma Brown, R. Eckersley
{"title":"Acoustic Wave Sparsely-Activated Localization Microscopy (AWSALM): In Vivo Fast Ultrasound Super-Resolution Imaging using Nanodroplets","authors":"Ge Zhang, P. Weinberg, C. Dunsby, M. Tang, S. Harput, M. Toulemonde, Jacob Broughton-Venner, Jiaqi Zhu, K. Riemer, K. Christensen-Jeffries, Jemma Brown, R. Eckersley","doi":"10.1109/ULTSYM.2019.8926069","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8926069","url":null,"abstract":"Current localization-based super-resolution ultrasound imaging requires a low concentration of flowing microbubbles to visualize microvasculature beyond the diffraction limit and acquisition is slow. Nanodroplets offer a promising solution as they can be sparsely activated and deactivated on-demand. In this study, acoustic wave sparsely-activated localization microscopy (AWSALM) using activation and deactivation of nanodroplets, an acoustic counterpart of photo-activated localization microscopy (PALM) which is less dependent on agent concentration and the presence of flow, is demonstrated for super-resolution imaging in deep tissues in vivo. An in vivo super-resolution image of a rabbit kidney is obtained in 1.1 seconds using AWSALM, where micro-vessels with apparent sizes far below the half-wavelength of 220 µm were visualized. This preliminary result demonstrates the feasibility of applying AWSALM for in vivo super-resolution imaging.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"27 1","pages":"1930-1933"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86991861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brendan L. West, Jian Zhou, C. Chakrabarti, T. Wenisch
{"title":"Delay Compression: Reducing Delay Calculation Requirements for 3D Plane-Wave Ultrasound","authors":"Brendan L. West, Jian Zhou, C. Chakrabarti, T. Wenisch","doi":"10.1109/ULTSYM.2019.8925725","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925725","url":null,"abstract":"In 3D plane-wave ultrasound, computational requirements are directly proportional to the number of focal points in a volume. For a receive aperture of size of M<inf>x</inf>M<inf>y</inf> transducers, a beamforming aperture size of N<inf>x</inf>N<inf>y</inf>, and a depth of M<inf>z</inf> focal points, M<inf>x</inf> M<inf>y</inf> M<inf>z</inf> N<inf>x</inf> N<inf>y</inf> round-trip delays must be computed. To reduce this requirement, we decompose the planar transmit distance into two parts: (1) from the plane-wave’s origin to the first point in each focal line, and (2) from the plane when it is touching the first point in each focal line to each subsequent focal point along that line. The latter distance, as well as the reflection distances, are symmetric across beamforming apertures, and thus their computation can be shared. This decomposition results in up to a M<inf>x</inf> M<inf>y</inf> reduction in the number of unique delays while retaining full image quality. Using our technique, precomputing delays and storing them in look-up tables (LUTs) is now possible for 3D plane-wave ultrasound for the first time, opening new doors for computational architectures in this field. Our method works with 2D, 3D, and 3D-separable variants of plane-wave ultrasound.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"42 1","pages":"1278-1281"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87011641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Braz, P. M. Agnollitto, M. Nogueira-Barbosa, T. Pavan, Antonio A. O. Carneiro
{"title":"Diagnosis of osteoporosis using the low frequency acoustic response of mice femoral bones irradiated by a high frequency acoustic radiation pulse","authors":"G. Braz, P. M. Agnollitto, M. Nogueira-Barbosa, T. Pavan, Antonio A. O. Carneiro","doi":"10.1109/ULTSYM.2019.8925543","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925543","url":null,"abstract":"Quantitative characterization of the mechanical properties of bones is of great importance to diagnostic pathological processes. For example, osteoporotic bones have some differences in the mechanical properties if compared with the healthy ones. In this study a new technique based on acoustic radiation force has been used as an alternative to evaluate the differences in the mechanical properties of bones, that can lead to a new method to the diagnosis of bone diseases. The technique uses a single high-frequency ultrasound pulse (MHz) to excite the medium. Non-linear interactions of this acoustic wave in the tissue produces a lower frequency signal (kHz). Femoral bones where excised from 10 healthy mice and also from 10 mice where osteoporosis had been induced. Using µCT, the porosity, trabecular number, trabecular spacing, connectivity and the connectivity density of those bones where obtained. The following step was to irradiate those samples with a short focused acoustic radiation pulse (f=3.1 MHz, t=15 µs) and acquire the low frequency acoustic response using a dedicated hydrophone (ITC 6050) with acquisition band going from 1kHz to 70 kHz. A spectral analysis of the acquired signal has been done and the results compared with the µCT data in order to see if there where correlation between them. Also, a hypothesis test has been done to see if the technique can differentiate the samples coming from the healthy group and the osteoporotic. A strong correlation was obtained between the values from the spectral analysis of the low frequency acoustic response and from the trabecular number parameter µCT (spearman correlation coefficient of 0.72 and p-value of 0.02), also a moderate correlation has been found with the connectivity parameter ( spearman correlation coefficient of 0.69 and p-value of 0.03) showing that the technique is sensible to the mechanical parameters .","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"38 1","pages":"529-531"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87087154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonic Implant Localization for Wireless Power Transfer: Active Uplink and Harmonic Backscatter","authors":"Max L. Wang, T. Chang, A. Arbabian","doi":"10.1109/ULTSYM.2019.8926006","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8926006","url":null,"abstract":"Efficient ultrasonic power transfer to implantable devices requires precise transmitter beamforming to the receiver and can quickly degrade with small changes in implant location. Ultrasound localization can be used to find and track implants in the body to maintain an efficient link. We present a framework to calculate localization accuracy showing that sub-mm accuracy is obtainable using only three receive channels. A harmonic backscatter approach, which passively provides contrast in the frequency domain without active load modulation is compared to active uplink from the implant. The localization accuracy using both active uplink and harmonic backscatter from the implant power receiver is characterized using a linear array probe. The measured location standard deviation is nearly two orders of magnitude smaller than the half-power beamwidth of the array focal spot. Finally, beamforming using the measured location information increases the available power by over 20 × compared to an unfocused beam.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"1 1","pages":"818-821"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87095472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}