Journal of the Australian Ceramic Society最新文献_第3页

Optical properties, gamma attenuation and fast neutrons moderating performance of V2O5–Bi2O3–B2O3–PbO glasses V2O5-Bi2O3-B2O3-PbO玻璃的光学性质、γ衰减和快中子减缓性能

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-11-26 DOI: 10.1007/s41779-024-01122-7

Norah Alomayrah, M. S. Al-Buriahi

{"title":"Optical properties, gamma attenuation and fast neutrons moderating performance of V2O5–Bi2O3–B2O3–PbO glasses","authors":"Norah Alomayrah, M. S. Al-Buriahi","doi":"10.1007/s41779-024-01122-7","DOIUrl":"10.1007/s41779-024-01122-7","url":null,"abstract":"<div><p>This study investigated a new glass system containing various oxides, namely, V<sub>2</sub>O<sub>5</sub>, Bi<sub>2</sub>O<sub>3</sub>, B<sub>2</sub>O<sub>3</sub>, and PbO, with the aim of understanding their optical properties, gamma attenuation characteristics, and fast neutron moderation abilities. The optical properties were assessed through the refractive index and other parameters such as the reflectance loss (R<sup>loss</sup>), optical transmittance (T<sup>opt</sup>), molar polarizability, molar refractivity, metallization criterion (M), and static dielectric constant. Moreover, through a comprehensive theoretical analysis, the radiation shielding performance of the glass system was determined by computing their gamma and neutron attenuation factors. The PHITS Monte Carlo simulation code and the XCOM program were used to calculate the gamma radiation interaction parameters, while standard theoretical models were adopted for the estimation of neutron cross-sections. It was deduced from the obtained results that, as PbO concentration increased at the expense of V<sub>2</sub>O<sub>5</sub>, R<sup>loss</sup> decreased. Also, T<sup>opt</sup> increased with values of 0.6081, 0.6265, and 0.6514 for VBBP1, VBBP2, and VBBP3, respectively. The lowest half value layer (HVL) was observed at the lowest energy for the VBBP3 sample containing the highest PbO content. The synergistic effects arising from the combination of the various oxides offer unique opportunities for tailoring the optical and shielding attributes of the studied glasses to meet the demands of diverse optical, radiation shielding, and technological applications.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"517 - 527"},"PeriodicalIF":1.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of binder component and oxygen partial pressure on the high-temperature oxidation behaviors of WC cemented carbides 结合剂组分和氧分压对WC硬质合金高温氧化行为的影响

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-11-22 DOI: 10.1007/s41779-024-01107-6

Xingdong Su, Chengxin Li, Feng Liu, Minghui Li, Ruoyu Chen, Yulong Li, Danfeng Jiang, Zheng Kang

{"title":"The effect of binder component and oxygen partial pressure on the high-temperature oxidation behaviors of WC cemented carbides","authors":"Xingdong Su, Chengxin Li, Feng Liu, Minghui Li, Ruoyu Chen, Yulong Li, Danfeng Jiang, Zheng Kang","doi":"10.1007/s41779-024-01107-6","DOIUrl":"10.1007/s41779-024-01107-6","url":null,"abstract":"<div><p>The oxidation of the WC cemented carbides result in the formation of oxide phases, pores and cracks, ultimately reducing the performance and lifespan of the cemented carbide. Therefore, it is essential to study the oxidation behavior and mechanism of cemented carbide to improve its oxidation resistance and prolong its lifespan. The oxidation rate of cemented carbides is significantly affected by the components of the binder and oxygen partial pressures. When Ni and Zr are used as binders in preparing WC cemented carbides, improved oxidation resistance is attained because of the formation of a dense oxide layer on the cemented carbide surface under high oxygen partial pressures. When using 5% Ni & 15% Zr as the WC binder and oxidizing at 800 °C for 1 h, the oxidation rate reaches its peak at an oxygen partial pressure of 0.21, with an oxide layer thickness of 721 μm. Beyond this point, the oxidation rate decreases as the oxygen partial pressure increases. In contrast, using Fe and Zr as binders leads to an increase in surface flaws as the oxygen partial pressure increases. When using 10% Fe & 5% Zr as the WC binder and oxidizing at 800 °C for 1 h, the oxidation rate rises with increasing oxygen partial pressure, although the rate of increase progressively diminishes. Therefore, adjusting the binder components is an effective method for enhancing the oxidation resistance of WC cemented carbides.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"409 - 418"},"PeriodicalIF":1.8,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From waste to resource: energy-efficient production of glass-ceramic using blast furnace slag 从废物到资源：利用高炉渣节能生产玻璃陶瓷

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-11-19 DOI: 10.1007/s41779-024-01123-6

Majid Bagheri

{"title":"From waste to resource: energy-efficient production of glass-ceramic using blast furnace slag","authors":"Majid Bagheri","doi":"10.1007/s41779-024-01123-6","DOIUrl":"10.1007/s41779-024-01123-6","url":null,"abstract":"<div><p>The research successfully demonstrated the viability of producing high-quality glass-ceramics using blast furnace slag (BFS) through the petrurgic method compared with other energy-intensive methods. The findings revealed that this method not only reduces energy consumption but also effectively utilizes waste materials to form products with superior properties. The resultant glass-ceramic exhibited outstanding hardness and low water absorption, indicative of its dense and well-crystallized structure. However, its acid resistance was somewhat lower compared to its alkali resistance, which could be attributed to the chemical stability of the cuspidine phase in different environmental conditions. Future studies could explore further optimization of the material composition and processing conditions to enhance its acid resistance, potentially expanding the applications of these sustainable materials in various industrial sectors. This study underscores the potential of BFS as a valuable resource for the production of high-performance glass-ceramics, contributing to waste minimization and resource efficiency in the steel and ceramics industries.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"529 - 539"},"PeriodicalIF":1.8,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tobacco stem extract-mediated green synthesis of Fe-doped ZnO nanoparticles towards enhanced photocatalytic degradation of methylene blue and solar cell efficiency 烟草茎提取物介导的绿色合成fe掺杂ZnO纳米颗粒对提高光催化降解亚甲基蓝和太阳能电池效率的作用

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-10-24 DOI: 10.1007/s41779-024-01101-y

Orhan Baytar, Arzu Ekinci, Sinan Kutluay, Gurbet Canpolat, Ömer Şahin, Sabit Horoz

{"title":"Tobacco stem extract-mediated green synthesis of Fe-doped ZnO nanoparticles towards enhanced photocatalytic degradation of methylene blue and solar cell efficiency","authors":"Orhan Baytar, Arzu Ekinci, Sinan Kutluay, Gurbet Canpolat, Ömer Şahin, Sabit Horoz","doi":"10.1007/s41779-024-01101-y","DOIUrl":"10.1007/s41779-024-01101-y","url":null,"abstract":"<div><p>This study presents an innovative method for the synthesis of zinc oxide (ZnO) and iron-doped zinc oxide (Fe-doped ZnO) nanoparticles (NPs), employing extracts derived from tobacco stems. The environmentally friendly green synthesis process here represents the novelty of production and applications. Various analytical techniques including FT-IR, XRD, EDX, SEM and TEM were used to characterise ZnO and Fe-doped ZnO NPs. The study reveals that 1% Fe-doped ZnO NPs demonstrate markedly improved photocatalytic performance, attributed to a narrower band gap and enhanced charge separation. These NPs effectively promote the photocatalytic degradation of methylene blue, a promising approach for wastewater treatment and pollution control. Furthermore, the investigation of Fe-doped ZnO NPs in solar cells demonstrates their potential to substantially improve solar energy conversion efficiency. This novel approach paves the way for sustainable and eco-friendly advancements in both photocatalysis and photovoltaic technologies.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"60 5","pages":"1697 - 1708"},"PeriodicalIF":1.8,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142778547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reviewing and exploring boron oxide’s role in bioactive glasses: a synthesis of modeling and applications 氧化硼在生物活性玻璃中的作用综述与探索：建模与应用综述

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-10-17 DOI: 10.1007/s41779-024-01103-w

Takwa E. Ellakwa, Ayman Ellakwa, Ahmad S. Abu-Khadra, Hosam M. Gomaa, Fakiha El-Taib Heakal, Doha El-Sayed Ellakwa

{"title":"Reviewing and exploring boron oxide’s role in bioactive glasses: a synthesis of modeling and applications","authors":"Takwa E. Ellakwa, Ayman Ellakwa, Ahmad S. Abu-Khadra, Hosam M. Gomaa, Fakiha El-Taib Heakal, Doha El-Sayed Ellakwa","doi":"10.1007/s41779-024-01103-w","DOIUrl":"10.1007/s41779-024-01103-w","url":null,"abstract":"<div><p>Bioactive glasses, especially those based on borate, are characterized by their unique structural and mechanical properties, which are significantly influenced by boron content. Optimal boron levels enhance the thermal stability and bioactivity of these glasses, while excessive boron can degrade mechanical strength due to weaker -B-O-Si bonds. These materials are utilized in a range of applications, including bone regeneration, wound healing, and dental treatments. Advances in production methods, such as sol-gel techniques and melt-quenching, have led to improvements in their performance. Recent developments have produced bioglasses with enhanced antibacterial properties for blood-contact applications and those suitable for vascular tissue engineering. Comparatively, borate glasses convert to hydroxyapatite more rapidly than silicate glasses, providing advantages in medical applications. The bioactive potential of these materials is further enhanced by innovations like ion exchange and the creation of composite structures. Research continues to focus on optimizing these glasses to improve their bioactivity, mechanical properties, and adaptability to specific medical needs. The evolving field of bioactive glasses demonstrates significant promise for advancing tissue engineering and regenerative medicine, addressing both functional and biological requirements in various clinical settings.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"719 - 732"},"PeriodicalIF":1.8,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing micromechanical property characterization in ceramic multilayer coatings via hierarchical machine learning 基于分层机器学习的陶瓷多层涂层微力学性能表征

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-10-01 DOI: 10.1007/s41779-024-01098-4

Hachem Chaib, Shavan Askar, Harikumar Pallathadka, Sultan K. Salamah, M. K. Sharma, Marwan Kheimi

{"title":"Advancing micromechanical property characterization in ceramic multilayer coatings via hierarchical machine learning","authors":"Hachem Chaib, Shavan Askar, Harikumar Pallathadka, Sultan K. Salamah, M. K. Sharma, Marwan Kheimi","doi":"10.1007/s41779-024-01098-4","DOIUrl":"10.1007/s41779-024-01098-4","url":null,"abstract":"<div><p>This study focuses on a numerical data-driven machine learning (ML) approach applied to predict critical parameters, including hardness, Von Mises stress, and equivalent plastic strain in various ceramic multilayer coatings on a Ti alloy substrate, such as Ti/TiN, Ti/TiVN, Ti/TiZrN, Cr/CrN, Cr/CrAlN, and Ta/Ti-Zr-Ta, through the nanoindentation process. The regression analysis demonstrated the model’s effectiveness in predicting these parameters, with heightened accuracy in hardness and stress compared to plastic strain. The remarkable efficiency of the proposed hierarchical ML model derives from its ability to unravel complex interdependencies within the dataset, revealing subtle relationships that traditional models often overlook. The outcomes also revealed a direct correlation between increases in output targets, such as hardness and average Von Mises stress, and the amplification of weight factors associated with processing parameters. Conversely, heightened values of equivalent plastic strain demonstrated a proportional increase in weight factors associated with material properties. This observation underscores the individual contributions of processing parameters and material characteristics in modeling the mechanical behavior of multilayer coatings. Moreover, the ML model significantly enhanced the predictive performance for multilayer coatings by providing a detailed relevance score for the material properties of the layers. These properties included factors such as elastic modulus, hardness, Poisson ratio, and yield strength.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"553 - 568"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of BaO addition on the sintering properties and grain growth behavior of CaZrO3 ceramics 添加BaO对CaZrO3陶瓷烧结性能和晶粒生长行为的影响

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-09-30 DOI: 10.1007/s41779-024-01091-x

Huan Xu, Wangnian Zhang, Mengxian Zhang, Ming Cao, Xitang Wang

{"title":"The effect of BaO addition on the sintering properties and grain growth behavior of CaZrO3 ceramics","authors":"Huan Xu, Wangnian Zhang, Mengxian Zhang, Ming Cao, Xitang Wang","doi":"10.1007/s41779-024-01091-x","DOIUrl":"10.1007/s41779-024-01091-x","url":null,"abstract":"<div><p>In the present work, dense CaZrO<sub>3</sub> ceramics were prepared by a conventional solid-state reaction using high-purity commercial ZrO<sub>2</sub> and Ca(OH)<sub>2</sub> as raw materials, and BaO as a sintering aid. The effect of BaO addition on the sinterability, phase composition, and microstructures of CaZrO<sub>3</sub> ceramics was investigated. The grain growth kinetics was also analyzed based on the classical Brook model. The results showed that an appropriate amount of BaO addition has a significant positive contribution to the densification and grain growth of CaZrO<sub>3</sub> ceramics. However, excess addition gives rise to the formation of BaZrO<sub>3</sub> at the grain boundary, which dramatically hinders the grain growth and thus degrades the sinterability of CaZrO<sub>3</sub> ceramics. The enhanced sintering mechanism is related to lattice distortion generated from the substitution of Ca<sup>2+</sup> sites by larger Ba<sup>2+</sup> ions. The grain growth kinetics analysis demonstrated that the grain growth activation energy is affected by the BaO addition, and the value is decreased from 65.5 to 55.4 kJ·mol<sup>−1</sup> as the BaO content increases from 0 to 1 wt%.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"475 - 484"},"PeriodicalIF":1.8,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41779-024-01091-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Probing higher valences of uranium in nuclear materials using diffuse reflectance spectroscopy 利用漫反射光谱探测核材料中的高价铀

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-09-18 DOI: 10.1007/s41779-024-01090-y

Kaito Callan, Maria K. Nicholas, Timothy A. Ablott, Jamie J. Kruzic, Yingjie Zhang

{"title":"Probing higher valences of uranium in nuclear materials using diffuse reflectance spectroscopy","authors":"Kaito Callan, Maria K. Nicholas, Timothy A. Ablott, Jamie J. Kruzic, Yingjie Zhang","doi":"10.1007/s41779-024-01090-y","DOIUrl":"10.1007/s41779-024-01090-y","url":null,"abstract":"<div><p>Understanding uranium valences in nuclear materials is critical as it is known to influence both their physical and chemical properties. As such, the synthesis of uranium-containing materials with varied uranium oxidation states was achieved and their uranium valences, as determined by diffuse reflectance spectroscopy (DRS), herein reported. It was revealed that DRS was well suited to differentiating between U(IV), U(V) and U(VI) in these materials. The U(IV), visible as broad vibronic absorptions in the UV-vis region, U(V), present as sharp peaks arising from f-f transitions and thus restricted to the near-infrared region and U(VI), featured by broad charge transfer bands in the ultra-violet range, were successfully identified in mono-valent and mixed-valence materials. A particular sensitivity to U(V) was revealed, even when present as a minor species. Of particular note was the capability for DRS to determine the coordination environment about the U(V) centres, with a shift of the diagnostic peak to higher wavelengths when the uranium coordination number was changed from 6-fold to 7- and 8-fold. Highlighted in this work is the potential for DRS to be applied to the analysis of nuclear materials across the entirety of the nuclear fuel cycle, towards better understanding and improving their applications.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div><div><p><b>TOC</b>: The application of diffuse reflectance spectroscopy for probing uranium valences in nuclear materials spanning the entirety of the nuclear fuel cycle is presented, with selected cases highlighting the pros and cons of the technique as well as potential future work. Featured in this study is the sensitivity of the technique to the presence of U(V) and its coordination environment</p></div></div></figure></div></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"371 - 383"},"PeriodicalIF":1.8,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid tetracycline degradation by S-scheme Se/g-C3N4 heterostructure 利用 S 型 Se/g-C3N4 异质结构快速降解四环素

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-09-17 DOI: 10.1007/s41779-024-01088-6

Haoran Li, Zhijun Guo, Hassanali Azimi, Mehdi Ebadi, Abbas Shirmardi, Ramin Yousefi

{"title":"Rapid tetracycline degradation by S-scheme Se/g-C3N4 heterostructure","authors":"Haoran Li, Zhijun Guo, Hassanali Azimi, Mehdi Ebadi, Abbas Shirmardi, Ramin Yousefi","doi":"10.1007/s41779-024-01088-6","DOIUrl":"10.1007/s41779-024-01088-6","url":null,"abstract":"<div><p>This research presents an efficient and stable photocatalyst for the removal of hospital pollutants, characterized by a rapid reaction rate and a cost-effective, straightforward synthesis process. The study focuses on enhancing the photocatalytic performance of graphitic carbon nitride (g-C<sub>3</sub>N<sub>4</sub>, abbreviated as g-CN) through selenium (Se), leading to the formation of Se/g-CN nanocomposites. These nanocomposites were synthesized via a sintering method in a tube furnace, with varying selenium concentrations (5%, 10%, and 15% of Se/g-CN ratio). X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy confirmed the formation of a heterostructure between Se and g-CN. Field emission scanning electron microscopy (FESEM) images revealed that selenium incorporation altered the porous morphology of pristine g-CN, transforming it into a flake-like structure in the Se/g-CN nanocomposites. Tetracycline (TC) antibiotic was used as the target pollutant, with the Se(10%)/g-CN nanocomposites achieving 96% degradation under 60 min of commercial, low-power light-emitting diode (LED) irradiation. Additionally, the Se/g-CN heterostructures demonstrated stable photocatalytic activity, maintaining their performance after four cycles of reuse. Band structure calculations indicated that Se/g-CN forms an S-scheme heterostructure, where photogenerated electrons in g-CN act as reducing agents, and photogenerated holes in Se function as oxidizing agents.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"569 - 580"},"PeriodicalIF":1.8,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the in vitro cytotoxicity and drug delivery of ytterbium (III)-doped versatile bioactive glasses for cancer treatment 用于癌症治疗的掺镱 (III) 多功能生物活性玻璃的体外细胞毒性和药物输送评估

IF 1.8 4区材料科学

Journal of the Australian Ceramic Society Pub Date : 2024-09-17 DOI: 10.1007/s41779-024-01089-5

Aylin M. Deliormanlı, Harika Atmaca

{"title":"Evaluation of the in vitro cytotoxicity and drug delivery of ytterbium (III)-doped versatile bioactive glasses for cancer treatment","authors":"Aylin M. Deliormanlı, Harika Atmaca","doi":"10.1007/s41779-024-01089-5","DOIUrl":"10.1007/s41779-024-01089-5","url":null,"abstract":"<div><p>In this study, the in vitro mineralization, as well as an antitumor drug (fluorouracil) delivery of sol-gel-derived bioactive glasses doped with a lanthanide (III) element (Yb<sup>3+</sup>), have been investigated. Additionally, the cytotoxicity of the related bioactive glasses was examined against osteosarcoma SaOS-2 and osteoblastic MC3T3-E1 cell lines under in vitro conditions. The results demonstrated that the bioactive glass samples containing rare earth element did not induce cytotoxic effects on the mentioned cell lines for up to 7 days. An increase in alkaline phosphatase enzyme activity was observed for all samples during the incubation period. Drug loading experiments showed that the anticancer drug amount adsorbed onto the bioactive glass powders at pH 7.4 ranged between 25% and 35%. Based on the drug delivery studies conducted in phosphate-buffered saline solution at pH 7.4 and 5.5, cumulative drug release from the bioactive glass powders after 500 h was between 60% and 70% at neutral pH. A higher drug delivery was observed at lower pH value. The drug release kinetics were found to be consistent with the Higuchi model. The findings of this study indicate that bioactive glasses containing trivalent ytterbium possess suitable biological properties for use in biomedical applications and they offer improved biocompatibility providing an ideal environment for bone regeneration.</p></div>","PeriodicalId":673,"journal":{"name":"Journal of the Australian Ceramic Society","volume":"61 2","pages":"501 - 515"},"PeriodicalIF":1.8,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41779-024-01089-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0