美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.124016
A. Sharmin, F. Aminuzzaman, T. H. Ansari, M. Ahmed
{"title":"Morphological, Cultural, Molecular and Pathogenic Variation of <i>Bipolaris sorokiniana</i> in Wheat","authors":"A. Sharmin, F. Aminuzzaman, T. H. Ansari, M. Ahmed","doi":"10.4236/ajmb.2022.124016","DOIUrl":"https://doi.org/10.4236/ajmb.2022.124016","url":null,"abstract":"","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.121001
Huan Zhao, Xiaoyu Jiang, Ling-ling Lu, Qing Lin
{"title":"New Progress in Clinical Diagnosis, Treatment and Laboratory Testing of Acute Respiratory Infections in Children","authors":"Huan Zhao, Xiaoyu Jiang, Ling-ling Lu, Qing Lin","doi":"10.4236/ajmb.2022.121001","DOIUrl":"https://doi.org/10.4236/ajmb.2022.121001","url":null,"abstract":"Acute respiratory infection in children (ARTI) is the most common childhood infectious disease, and its pathogens include bacteria, fungi, viruses, chlamydia, mycoplasma and rickettsia. In recent years, with the continuous development of pathogen detection methods, the diagnosis and treatment of acute respiratory infections has received more and more attention from clini-cians. The clinical diagnosis and treatment of acute respiratory infections in children and the research of laboratory detection methods have also been continuously developed. The manuscript presents a review of progress in the clinical diagnosis, treatment and laboratory testing of acute respiratory infections in children by collecting references.","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.122003
Keita Odanaka
{"title":"Identification of a <i>Candida albicans</i> Biofilm Inhibitor","authors":"Keita Odanaka","doi":"10.4236/ajmb.2022.122003","DOIUrl":"https://doi.org/10.4236/ajmb.2022.122003","url":null,"abstract":"Candida albicans proliferates in the skin and oral cavity and is the causative agent of candida dermatitis and oral candidiasis. C. albicans is known to form biofilms on oral mucosa and denture surfaces. Formation of biofilms deteri-orates the permeability of antifungal drugs, decreasing their effectiveness. Therefore, in this study, I identified a compound with inhibitory activity against C. albicans biofilm formation. Heat shock protein 90 was selected as the target protein, and a potential ligand for the same was extracted and identified as 2-(4-methylpiperazin-1-yl)cyclopentanol. C. albicans was then cultured with varying concentrations of this compound: 0 mmol/L, 0.63 mmol/l. 2.5 mmol/l, and 10 mmol/l, and biofilm formation was measured via crystal violet assay. The findings demonstrated that 2-(4-methylpiperazin-1-yl)cyclo-pentanol substantially inhibits biofilm formation when added at a concentration of 0.63 mmol/l or higher. It is suggested that C. albicans could be elimi-nated more efficiently using this compound in combination with the existing antifungal drug miconazole. Further, the compound may also be useful as a disinfectant for medical devices, such as catheters, to prevent the formation of C. albicans biofilms.","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.123008
Salma Ibrahim, E. A. Mohammed, S. Taha, S. Yousif, H. Omer, O. Omer, Mirghani Seif-Elnasr, Seitelbanat Yassin, Y. Mohammed, O. A. Elhasan, Mohamed Taj-Eldin, A. Abakar, E. A. Ahmed, S. Elzaki
{"title":"Incidence of Oxa23 and Oxa51 Genes Associated with Bacterial Isolated from Patients with Urosepsis: Single Centre Prespective","authors":"Salma Ibrahim, E. A. Mohammed, S. Taha, S. Yousif, H. Omer, O. Omer, Mirghani Seif-Elnasr, Seitelbanat Yassin, Y. Mohammed, O. A. Elhasan, Mohamed Taj-Eldin, A. Abakar, E. A. Ahmed, S. Elzaki","doi":"10.4236/ajmb.2022.123008","DOIUrl":"https://doi.org/10.4236/ajmb.2022.123008","url":null,"abstract":"","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.124013
Ruluo Qian, Changshuan Xiao, Yaping Liu, Jingzhe Yang
{"title":"The Protective Effects of Preventive Atomisation Inhalation of Edaravone on the Lung Tissues of Rats with Smoke Inhalation Injury","authors":"Ruluo Qian, Changshuan Xiao, Yaping Liu, Jingzhe Yang","doi":"10.4236/ajmb.2022.124013","DOIUrl":"https://doi.org/10.4236/ajmb.2022.124013","url":null,"abstract":"","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.124014
U. Ufot, I. Okop, Mfoniso P. Uko, Imekan Isaac Akpan, Khasim Cali, M. Akpanabiatu
{"title":"The Roles of pH in the Modification of Wild-Type Recombinant <i>Phlebia radiata</i> Manganese Peroxidase 3 Activities and Stability of Secondary Structures","authors":"U. Ufot, I. Okop, Mfoniso P. Uko, Imekan Isaac Akpan, Khasim Cali, M. Akpanabiatu","doi":"10.4236/ajmb.2022.124014","DOIUrl":"https://doi.org/10.4236/ajmb.2022.124014","url":null,"abstract":"","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.123009
Ning Ma, Xiaohong Li, Renyi Wu
{"title":"Effect of cAMP and cGMP on Connexin43 Expression in Isolated Human and Bovine Ciliary Epithelium","authors":"Ning Ma, Xiaohong Li, Renyi Wu","doi":"10.4236/ajmb.2022.123009","DOIUrl":"https://doi.org/10.4236/ajmb.2022.123009","url":null,"abstract":"","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diversity and Distribution of Staphylococcal Chromosomal Cassettes Mec (SCCmec) Types I, II and III in Coagulase-Negative Staphylococcal Strains Isolated from Surfaces and Medico-Technical Materials of the University Hospital of Abomey-Calavi/Sô-Ava","authors":"Nanoukon Chimène, C. Fresnel, Djèdatin Gustave, Sina Haziz, Socohou Akim, Dado Aurel, Kougblènou Enorck, Badé Farid, Agbangla Clémént, Baba-Moussa Lamine Saïd","doi":"10.4236/ajmb.2022.123011","DOIUrl":"https://doi.org/10.4236/ajmb.2022.123011","url":null,"abstract":"The coagulase-negative staphylococci (CoNS) have long been considered to be low pathogenicity. The possibility of a horizontal transfer of resistance and virulence genes from S. aureus to CoNS could increase the pathogenicity of these bacteria. showed resistance to methicillin. However, only 28.5% (20/70) carried the mecA gene. SCCmec was identified in only 17.14% (12/70) of these strains. Four strains carried mecA gene as well as one of the three types of SCCmec searched. SCCmec types I, II and III were identified in CoNS strains studied. SCCmec type I was the most frequent chromosomal cassette in mecA + strains, only or in association with another SCCmec. The study also revealed methicillin-resistant strains carrying SCCmec lacking the mecA gene. Finally, 60% (12/20) of the strains were found to be non-typeable. Our results show that CoNS strains present a high resistance to methicillin and the source of this resistance in the CoNS of our study is not only the mecA gene. There is also a high diversity of SCCmec, justified by a large number of non-typeable CoNS strains. The mecA − SCCmec + methicillin-resistant strains deserve to be sequenced for further studies.","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
美国分子生物学期刊(英文)Pub Date : 2022-01-01DOI: 10.4236/ajmb.2022.122004
S. Yousif, A. Abakar, S. Elzaki, Salma Ibrahim, O. A. Elhasan, Mohamed Taj-Eldin, E. A. Ahmed
{"title":"Study on PVL, blaOXA-23 and blaOXA-51 Genes in Drug Resistant <i>Staphylococcus aureus</i> Causing Surgical-Sites and Traumatic Wounds Infections, Sudan","authors":"S. Yousif, A. Abakar, S. Elzaki, Salma Ibrahim, O. A. Elhasan, Mohamed Taj-Eldin, E. A. Ahmed","doi":"10.4236/ajmb.2022.122004","DOIUrl":"https://doi.org/10.4236/ajmb.2022.122004","url":null,"abstract":"","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}