美国分子生物学期刊(英文)最新文献_第3页

Morphological, Cultural, Molecular and Pathogenic Variation of Bipolaris sorokiniana in Wheat 小麦褐飞蛾的形态、培养、分子和致病变异

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.124016

A. Sharmin, F. Aminuzzaman, T. H. Ansari, M. Ahmed

引用次数: 1

New Progress in Clinical Diagnosis, Treatment and Laboratory Testing of Acute Respiratory Infections in Children 儿童急性呼吸道感染的临床诊断、治疗和实验室检测新进展

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.121001

Huan Zhao, Xiaoyu Jiang, Ling-ling Lu, Qing Lin

引用次数: 0

M₃ Muscarinic Acetylcholine Receptor Antagonist Darifenacin Protects against Pulmonary Fibrosis through ERK/NF-κB/miR-21 Pathway M3毒蕈碱乙酰胆碱受体拮抗剂达利那新通过ERK/NF-κB/miR-21通路抑制肺纤维化

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.122002

Y. Liu, Yanan Jiang, Chao Wang, Haiying Zhang, Yan Liu

引用次数: 0

Identification of a Candida albicans Biofilm Inhibitor 白色念珠菌生物膜抑制剂的鉴定

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.122003

Keita Odanaka

{"title":"Identification of a <i>Candida albicans</i> Biofilm Inhibitor","authors":"Keita Odanaka","doi":"10.4236/ajmb.2022.122003","DOIUrl":"https://doi.org/10.4236/ajmb.2022.122003","url":null,"abstract":"Candida albicans proliferates in the skin and oral cavity and is the causative agent of candida dermatitis and oral candidiasis. C. albicans is known to form biofilms on oral mucosa and denture surfaces. Formation of biofilms deteri-orates the permeability of antifungal drugs, decreasing their effectiveness. Therefore, in this study, I identified a compound with inhibitory activity against C. albicans biofilm formation. Heat shock protein 90 was selected as the target protein, and a potential ligand for the same was extracted and identified as 2-(4-methylpiperazin-1-yl)cyclopentanol. C. albicans was then cultured with varying concentrations of this compound: 0 mmol/L, 0.63 mmol/l. 2.5 mmol/l, and 10 mmol/l, and biofilm formation was measured via crystal violet assay. The findings demonstrated that 2-(4-methylpiperazin-1-yl)cyclo-pentanol substantially inhibits biofilm formation when added at a concentration of 0.63 mmol/l or higher. It is suggested that C. albicans could be elimi-nated more efficiently using this compound in combination with the existing antifungal drug miconazole. Further, the compound may also be useful as a disinfectant for medical devices, such as catheters, to prevent the formation of C. albicans biofilms.","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of Oxa23 and Oxa51 Genes Associated with Bacterial Isolated from Patients with Urosepsis: Single Centre Prespective 尿脓毒症患者分离细菌相关Oxa23和Oxa51基因的发生率:单中心预测

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.123008

Salma Ibrahim, E. A. Mohammed, S. Taha, S. Yousif, H. Omer, O. Omer, Mirghani Seif-Elnasr, Seitelbanat Yassin, Y. Mohammed, O. A. Elhasan, Mohamed Taj-Eldin, A. Abakar, E. A. Ahmed, S. Elzaki

引用次数: 0

The Protective Effects of Preventive Atomisation Inhalation of Edaravone on the Lung Tissues of Rats with Smoke Inhalation Injury 预防性雾化吸入依达拉奉对烟雾吸入性损伤大鼠肺组织的保护作用

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.124013

Ruluo Qian, Changshuan Xiao, Yaping Liu, Jingzhe Yang

引用次数: 0

The Roles of pH in the Modification of Wild-Type Recombinant Phlebia radiata Manganese Peroxidase 3 Activities and Stability of Secondary Structures pH对重组放线菌锰过氧化物酶3活性及二级结构稳定性的影响

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.124014

U. Ufot, I. Okop, Mfoniso P. Uko, Imekan Isaac Akpan, Khasim Cali, M. Akpanabiatu

引用次数: 0

Effect of cAMP and cGMP on Connexin43 Expression in Isolated Human and Bovine Ciliary Epithelium cAMP和cGMP对人、牛睫状上皮连接蛋白43表达的影响

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.123009

Ning Ma, Xiaohong Li, Renyi Wu

引用次数: 0

Diversity and Distribution of Staphylococcal Chromosomal Cassettes Mec (SCCmec) Types I, II and III in Coagulase-Negative Staphylococcal Strains Isolated from Surfaces and Medico-Technical Materials of the University Hospital of Abomey-Calavi/Sô-Ava Abomey-Calavi大学医院表面和医疗技术材料中分离的凝固酶阴性葡萄球菌I型、II型和III型葡萄球菌染色体卡带Mec (SCCmec)的多样性和分布/Sô-Ava

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.123011

Nanoukon Chimène, C. Fresnel, Djèdatin Gustave, Sina Haziz, Socohou Akim, Dado Aurel, Kougblènou Enorck, Badé Farid, Agbangla Clémént, Baba-Moussa Lamine Saïd

{"title":"Diversity and Distribution of Staphylococcal Chromosomal Cassettes Mec (SCCmec) Types I, II and III in Coagulase-Negative Staphylococcal Strains Isolated from Surfaces and Medico-Technical Materials of the University Hospital of Abomey-Calavi/Sô-Ava","authors":"Nanoukon Chimène, C. Fresnel, Djèdatin Gustave, Sina Haziz, Socohou Akim, Dado Aurel, Kougblènou Enorck, Badé Farid, Agbangla Clémént, Baba-Moussa Lamine Saïd","doi":"10.4236/ajmb.2022.123011","DOIUrl":"https://doi.org/10.4236/ajmb.2022.123011","url":null,"abstract":"The coagulase-negative staphylococci (CoNS) have long been considered to be low pathogenicity. The possibility of a horizontal transfer of resistance and virulence genes from S. aureus to CoNS could increase the pathogenicity of these bacteria. showed resistance to methicillin. However, only 28.5% (20/70) carried the mecA gene. SCCmec was identified in only 17.14% (12/70) of these strains. Four strains carried mecA gene as well as one of the three types of SCCmec searched. SCCmec types I, II and III were identified in CoNS strains studied. SCCmec type I was the most frequent chromosomal cassette in mecA + strains, only or in association with another SCCmec. The study also revealed methicillin-resistant strains carrying SCCmec lacking the mecA gene. Finally, 60% (12/20) of the strains were found to be non-typeable. Our results show that CoNS strains present a high resistance to methicillin and the source of this resistance in the CoNS of our study is not only the mecA gene. There is also a high diversity of SCCmec, justified by a large number of non-typeable CoNS strains. The mecA − SCCmec + methicillin-resistant strains deserve to be sequenced for further studies.","PeriodicalId":65391,"journal":{"name":"美国分子生物学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70513349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on PVL, blaOXA-23 and blaOXA-51 Genes in Drug Resistant Staphylococcus aureus Causing Surgical-Sites and Traumatic Wounds Infections, Sudan 苏丹耐药金黄色葡萄球菌引起手术部位和创伤创面感染的PVL、blaOXA-23和blaOXA-51基因研究

美国分子生物学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ajmb.2022.122004

S. Yousif, A. Abakar, S. Elzaki, Salma Ibrahim, O. A. Elhasan, Mohamed Taj-Eldin, E. A. Ahmed

引用次数: 0